Browse by Basel Contributors ID
Zou, Zhi and Wu, Shuke and Ward, Thomas R. and Chen, Dongping and Tachibana, Ryo and Gerngross, Daniel and Lozhkin, Boris. (2024) Combining an artificial metathase with a fatty acid decarboxylase in a whole cell for cycloalkene synthesis. Nature Synthesis, 3. pp. 1113-1123. Igareta, Nico V. and Tachibana, Ryo and Spiess, Daniel C. and Peterson, Ryan L. and Ward, Thomas R.. (2023) Spiers Memorial Lecture: Shielding the active site: a streptavidin superoxide-dismutase chimera as a host protein for asymmetric transfer hydrogenation. FARADAY DISCUSSIONS, 244. pp. 9-20. Ward, Thomas R. and Copéret, Christophe. (2023) Introduction: Bridging the Gaps: Learning from Catalysis across Boundaries. Chemical Reviews, 123 (9). pp. 5221-5224. Beweries, Torsten and Buchmeiser, Michael R. and Bugden, Frances E. and Champness, Neil R. and Chanbasha, Basheer and Costas, Miquel and Echeverria, Jorge and Eisenstein, Odile and Ferguson, Calum and Goodall, Joe C. and Gramage-Doria, Rafael and Greenhalgh, Mark and Gyton, Matthew and Ham, Rens and Kennepohl, Pierre and Lewandowski, Bartosz and Liu, Wei-Chun and Macgregor, Stuart A. and Mahmudov, Kamran T. and Meeus, Eva and Morris, Josh and Ntola, Pinkie and Parac-Vogt, Tatjana N. and Perutz, Robin N. and Poater, Albert and Powers, David and Raithby, Paul R. and Reek, Joost N. H. and Riddell, Imogen and Ward, Thomas R. and Weller, Andrew S. and Wennemers, Helma. (2023) Make - underpinning concepts of the synthesis of systems where non-covalent interactions are important: general discussion. Faraday Discussions, 244. pp. 434-454. Beweries, Torsten and Buchmeiser, Michael R. R. and Champness, Neil R. R. and Costas, Miquel and Duhme-Klair, Anne and Echeverria, Jorge and Eisenstein, Odile and Ferguson, Calum T. J. and Goodall, Joe C. C. and Gramage-Doria, Rafael and Gyton, Matthew and Ham, Rens and Herres-Pawlis, Sonja and Johnson, Chloe L. L. and Kennepohl, Pierre and Lewandowski, Bartosz and Linnebank, Pim R. R. and Macgregor, Stuart A. A. and Mahmudov, Kamran T. T. and Meeus, Eva and Navarro, Miquel and Ntola, Pinkie and Parac-Vogt, Tatjana N. N. and Perutz, Robin N. N. and Poater, Albert and Powers, David C. C. and Pullen, Sonja and Raithby, Paul R. R. and Reek, Joost N. H. and Ward, Thomas R. R. and Weller, Andrew S. S. and Wennemers, Helma. (2023) Manipulate - techniques to manipulate the surroundings of a synthetic catalyst to control activity and selectivity: general discussion. Faraday Discussions, 244. pp. 96-118. Chanbasha, Basheer and Costas, Miquel and Echeverria, Jorge and Eisenstein, Odile and Greenhalgh, Mark and Kennepohl, Pierre and Kirrander, Adam and Linnebank, Pim R. R. and Macgregor, Stuart A. A. and Mahmudov, Kamran T. T. and Martin-Fernandez, Carlos and Meeus, Eva and Perutz, Robin N. and Poater, Albert N. and Morris, Josh and Reek, Joost N. H. and Rouse, Ian and Toste, Dean and Trujillo, Cristina and Ward, Thomas R. and Weinstein, Julia A. A. and Weller, Andrew S. S.. (2023) Model - state-of-the-art modelling and computational analysis of reactive sites: general discussion. Faraday Discussions, 244. pp. 336-355. Wang, Weijin and Tachibana, Ryo and Zou, Zhi and Chen, Dongping and Zhang, Xiang and Lau, Kelvin and Pojer, Florence and Ward, Thomas R. and Hu, Xile. (2023) Manganese Transfer Hydrogenases Based on the Biotin-Streptavidin Technology. Angewandte Chemie International Edition. e202311896. Waser, Valerie and Mukherjee, Manjistha and Tachibana, Ryo and Igareta, Nico V. and Ward, Thomas R.. (2023) An Artificial [Fe₄S₄]-Containing Metalloenzyme for the Reduction of CO₂ to Hydrocarbons. Journal of the American Chemical Society, 145 (27). pp. 14823-14830. Yu, Kun and Zou, Zhi and Igareta, Nico V. and Tachibana, Ryo and Bechter, Julia and Köhler, Valentin and Chen, Dongping and Ward, Thomas R.. (2023) Artificial Metalloenzyme-Catalyzed Enantioselective Amidation via Nitrene Insertion in Unactivated C(sp³)–H Bonds. Journal of the American Chemical Society, 145 (30). pp. 16621-16629. Waser, Valerie and Ward, Thomas R.. (2023) Aqueous stability and redox chemistry of synthetic [Fe₄S₄] clusters. Coordination chemistry reviews, 495. p. 215377. Vornholt, Tobias and Jončev, Zlatko and Sabatino, Valerio and Panke, Sven and Sparr, Christof and Ward, Thomas R. and Jeschek, Markus. (2023) An Artificial Metalloenzyme for Atroposelective Metathesis. ChemCatChem, 15 (23). e202301113. Zhang, Xiang and Ward, Thomas R. and Burgener, Simon and Dačević, Bratislav. (2023) Binding Interactions and Inhibition Mechanisms of Gold Complexes in Thiamine Diphosphate-Dependent Enzymes. Biochemistry, 62 (22). pp. 3303-3311. Stein, Alina and Liang, Alexandria Deliz and Sahin, Reyhan and Ward, Thomas R.. (2022) Incorporation of metal-chelating unnatural amino acids into halotag for allylic deamination. Journal of Organometallic Chemistry, 962. p. 122272. Schreier, Mirjam R. and Guo, Xingwei and Pfund, Björn and Okamoto, Yasunori and Ward, Thomas R. and Kerzig, Christoph and Wenger, Oliver S.. (2022) Water-Soluble Tris(cyclometalated) Iridium(III) Complexes for Aqueous Electron and Energy Transfer Photochemistry. Accounts of Chemical Research, 55 (9). pp. 1290-1300. Rumo, Corentin and Stein, Alina and Klehr, Juliane and Tachibana, Ryo and Prescimone, Alessandro and Haussinger, Daniel and Ward, Thomas R.. (2022) An Artificial Metalloenzyme Based on a Copper Heteroscorpionate Enables sp³ C-H Functionalization via Intramolecular Carbene Insertion. Journal of the American Chemical Society, 144 (26). pp. 11676-11684. Vallapurackal, Jaicy and Stucki, Ariane and Liang, Alexandria Deliz and Klehr, Juliane and Dittrich, Petra S. and Ward, Thomas R.. (2022) Ultrahigh-Throughput Screening of an Artificial Metalloenzyme using Double Emulsions. Angewandte Chemie International Edition, 61 (48). e202207328. Hirschi, Stephan and Ward, Thomas R. and Meier, Wolfgang P. and Müller, Daniel J. and Fotiadis, Dimitrios. (2022) Synthetic Biology: Bottom-Up Assembly of Molecular Systems. Chemical Reviews, 122 (21). pp. 16294-16328. Burgener, Simon and Ward, Thomas R.. (2022) Dihydrogen-dependent carbon dioxide reductase: Hardwired for CO₂ reduction. Chem Catalysis, 2 (10). pp. 2427-2429. Stucki, Ariane and Vallapurackal, Jaicy and Ward, Thomas R. and Dittrich, Petra S.. (2021) Droplet Microfluidics and Directed Evolution of Enzymes: an Intertwined Journey. Angewandte Chemie International Edition. n/a. Vornholt, Tobias and Christoffel, Fadri and Pellizzoni, Michela M. and Panke, Sven and Ward, Thomas R. and Jeschek, Markus. (2021) Systematic engineering of artificial metalloenzymes for new-to-nature reactions. Science Advances, 7 (4). eabe4208. Lozhkin, Boris and Ward, Thomas R.. (2021) A Close-to-Aromatize Approach for the Late-Stage Functionalization through Ring Closing Metathesis. Helvetica Chimica Acta, 104 (5). e2100024. Fischer, Sandro and Ward, Thomas R. and Liang, Alexandria D.. (2021) Engineering a Metathesis-Catalyzing Artificial Metalloenzyme Based on HaloTag. ACS Catalysis, 11 (10). pp. 6343-6347. Di Leone, Stefano and Vallapurackal, Jaicy and Yorulmaz Avsar, Saziye and Kyropolou, Myrto and Ward, Thomas R. and Palivan, Cornelia G. and Meier, Wolfgang. (2021) Expanding the Potential of the Solvent-Assisted Method to Create Bio-Interfaces from Amphiphilic Block Copolymers. Biomacromolecules, 22 (7). pp. 3005-3016. Lozhkin, Boris and Ward, Thomas R.. (2021) Bioorthogonal strategies for the in vivo synthesis or release of drugs. Bioorganic & medicinal chemistry, 45. p. 116310. Christoffel, Fadri and Igareta, Nico and Pellizzoni, Michela M. and Tiessler-Sala, Laura and Lozhkin, Boris and Spiess, Daniel C. and Lledos, Agusti and Marechal, Jean-Didier and Peterson, Ryan L. and Ward, Thomas R.. (2021) Design and evolution of chimeric streptavidin for protein-enabled dual gold catalysis. Nature Catalysis , 4 (8). pp. 643-653. Baiyoumy, Alain and Vallapurackal, Jaicy and Schwizer, Fabian and Heinisch, Tillmann and Kardashliev, Tsvetan and Held, Martin and Panke, Sven and Ward, Thomas R.. (2021) Directed Evolution of a Surface-Displayed Artificial Allylic Deallylase Relying on a GFP Reporter Protein. ACS Catalysis, 11 (17). pp. 10705-10712. Miró-Vinyals, Carla and Stein, Alina and Fischer, Sandro and Ward, Thomas R. and Deliz Liang, Alexandria. (2021) HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridium Dye. ChemBioChem, 22 (24). pp. 3398-3401. Stein, Alina and Chen, Dongping and Igareta, Nico V. and Cotelle, Yoann and Rebelein, Johannes G. and Ward, Thomas R.. (2021) A Dual Anchoring Strategy for the Directed Evolution of Improved Artificial Transfer Hydrogenases Based on Carbonic Anhydrase. ACS Central Science, 7 (11). pp. 1874-1884. Miller, Kelsey R. and Paretsky, Jonathan D. and Follmer, Alec H. and Heinisch, Tillmann and Mittra, Kaustuv and Gul, Sheraz and Kim, In-Sik and Fuller, Franklin D. and Batyuk, Alexander and Sutherlin, Kyle D. and Brewster, Aaron S. and Bhowmick, Asmit and Sauter, Nicholas K. and Kern, Jan and Yano, Junko and Green, Michael T. and Ward, Thomas R. and Borovik, A. S.. (2020) Artificial Iron Proteins: Modeling the Active Sites in Non-Heme Dioxygenases. Inorganic Chemistry, 59 (9). pp. 6000-6009. Serrano-Plana, Joan and Rumo, Corentin and Rebelein, Johannes G. and Peterson, Ryan L. and Barnet, Maxime and Ward, Thomas R.. (2020) Enantioselective Hydroxylation of Benzylic C(sp; 3; )-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology. Journal of the American Chemical Society, 142 (24). pp. 10617-10623. Sabatino, Valerio and Staub, Dario and Ward, Thomas R.. (2020) Synthesis of N-Substituted Indoles via Aqueous Ring-Closing Metathesis. Catalysis Letters, 151 (1). pp. 17-7. Davis, Holly Jane and Häussinger, Daniel and Ward, Thomas R. and Okamoto, Yasunori. (2020) A visible-light promoted amine oxidation catalyzed by a Cp*Ir complex. ChemCatChem, 12 (18). pp. 4512-4516. Bullock, R. Morris and Chen, Jingguang G. and Gagliardi, Laura and Chirik, Paul J. and Farha, Omar K. and Hendon, Christopher H. and Jones, Christopher W. and Keith, John A. and Klosin, Jerzy and Minteer, Shelley D. and Morris, Robert H. and Radosevich, Alexander T. and Rauchfuss, Thomas B. and Strotman, Neil A. and Vojvodic, Aleksandra and Ward, Thomas R. and Yang, Jenny Y. and Surendranath, Yogesh. (2020) Using nature's blueprint to expand catalysis with Earth-abundant metals. Science, 369 (6505). p. 3183. Samanta, Avik and Sabatino, Valerio and Ward, Thomas R. and Walther, Andreas. (2020) Functional and morphological adaptation in DNA protocells via signal processing prompted by artificial metalloenzymes. Nature Nanotechnology, 15 (11). pp. 914-921. Klehr, Juliane and Zhao, Jingming and Kron, Amanda Santos and Ward, Thomas R. and Köhler, Valentin. (2020) Streptavidin (Sav)-Based Artificial Metalloenzymes: Cofactor Design Considerations and Large-Scale Expression of Host Protein Variants. In: Peptide and Protein Engineering. New York, pp. 213-235. Liang, Alexandria Deliz and Serrano-Plana, Joan and Peterson, Ryan L. and Ward, Thomas R.. (2019) Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology: Enzymatic Cascades and Directed Evolution. Accounts of Chemical Research, 52 (3). pp. 585-595. Rebelein, Johannes G. and Cotelle, Yoann and Garabedian, Brett and Ward, Thomas R.. (2019) Chemical Optimization of Whole-Cell Transfer Hydrogenation Using Carbonic Anhydrase as Host Protein. ACS Catalysis, 9 (5). pp. 4173-4178. Guo, Xingwei and Okamoto, Yasunori and Schreier, Mirjam R. and Ward, Thomas R. and Wenger, Oliver S.. (2019) Reductive Amination and Enantioselective Amine Synthesis by Photoredox Catalysis. European Journal of Organic Chemistry. Davis, Holly J. and Ward, Thomas R.. (2019) Artificial Metalloenzymes: Challenges and Opportunities. ACS Central Science, 5 (7). pp. 1120-1136. Cheng, Yangyang and Zong, Lili and Lopez-Andarias, Javier and Bartolami, Eline and Okamoto, Yasunori and Ward, Thomas R. and Sakai, Naomi and Matile, Stefan. (2019) Cell-Penetrating Dynamic-Covalent Benzopolysulfane Networks. Angewandte Chemie International Edition, 58 (28). pp. 9522-9526. Bartolami, Eline and Basagiannis, Dimitris and Zong, Lili and Martinent, Remi and Okamoto, Yasunori and Laurent, Quentin and Ward, Thomas R. and Gonzalez-Gaitan, Marcos and Sakai, Naomi and Matile, Stefan. (2019) Diselenolane-Mediated Cellular Uptake: Efficient Cytosolic Delivery of Probes, Peptides, Proteins, Artificial Metalloenzymes and Protein-Coated Quantum Dots. Chemistry - A European Journal, 25 (16). pp. 4047-4051. Sabatino, Valerio and Ward, Thomas R.. (2019) Aqueous olefin metathesis: recent developments and applications. Beilstein Journal of Organic Chemistry, 15. pp. 445-468. Sabatino, Valerio and Rebelein, Johannes G. and Ward, Thomas R.. (2019) "Close-to-Release": Spontaneous Bioorthogonal Uncaging Resulting from Ring-Closing Metathesis. Journal of the American Chemical Society, 141 (43). pp. 17048-17052. Wu, Shuke and Zhou, Yi and Rebelein, Johannes G. and Kuhn, Miriam and Mallin, Hendrik and Zhao, Jingming and Igareta, Nico V. and Ward, Thomas R.. (2019) Breaking Symmetry: Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes. Journal of the American Chemical Society, 141 (40). pp. 15869-15878. Wu, Shuke and Zhou, Yi and Gerngross, Daniel and Jeschek, Markus and Ward, Thomas R.. (2019) Chemo-enzymatic cascades to produce cycloalkenes from bio-based resources. Nature Communications, 10. p. 5060. Ward, Thomas R.. (2019) ACS Central Science Virtual Issue on Bioinspired Catalysis. ACS Central Science, 5 (11). pp. 1732-1735. Hartwig, John F. and Ward, Thomas R.. (2019) New "Cats" in the House: Chemistry Meets Biology in Artificial Metalloenzymes and Repurposed Metalloenzymes. Accounts of Chemical Research, 52 (5). p. 1145. Jeschek, Markus and Panke, Sven and Ward, Thomas R.. (2018) Artificial Metalloenzymes on the Verge of New-to-Nature Metabolism. Trends in Biotechnology, 36 (1). pp. 60-72. Rebelein, Johannes G. and Ward, Thomas R.. (2018) In vivo catalyzed new-to-nature reactions. Current Opinion in Biotechnology, 53. pp. 106-114. Schwizer, Fabian and Okamoto, Yasunori and Heinisch, Tillmann and Gu, Yifan and Pellizzoni, Michela M. and Lebrun, Vincent and Reuter, Raphael and Köhler, Valentin and Lewis, Jared C. and Ward, Thomas R.. (2018) Artificial Metalloenzymes: Reaction Scope and Optimization Strategies. Chemical Reviews, 118 (1). pp. 142-231. Guo, Xingwei and Okamoto, Yasunori and Schreier, Mirjam R. and Ward, Thomas R. and Wenger, Oliver S.. (2018) Enantioselective Synthesis of Amines by Combining Photoredox and Enzymatic Catalysis in a Cyclic Reaction Network. Chemical Science, 9. pp. 5052-5056. Zhao, Jingming and Bachmann, Daniel G. and Lenz, Markus and Gillingham, Dennis G. and Ward, Thomas R.. (2018) An artificial metalloenzyme for carbene transfer based on a biotinylated dirhodium anchored within streptavidin. Catalysis science & technology, 8 (9). pp. 2294-2298. Hestericova, Martina and Heinisch, Tillmann and Lenz, Markus and Ward, Thomas R.. (2018) Ferritin encapsulation of artificial metalloenzymes: engineering a tertiary coordination sphere for an artificial transfer hydrogenase. Dalton transactions, 47 (32). pp. 10837-10841. Hestericová, Martina and Heinisch, Tillman and Alonso-Cotchico, Lur and Maréchal, Jean-Didier and Vidossich, Pietro and Ward, Thomas R.. (2018) Directed Evolution of an Artificial Imine Reductase. Angewandte Chemie - International Edition, 57 (7). pp. 1863-1868. Pellizzoni, Michela M. and Schwizer, Fabian and Wood, Christopher W. and Sabatino, Valerio and Cotelle, Yoann and Matile, Stefan and Woolfson , Derek N. and Ward, Thomas R.. (2018) Chimeric Streptavidins as Host Proteins for Artificial Metalloenzymes. ACS Catalysis, 8 (2). pp. 1476-1484. Christoffel, Fadri and Ward, Thomas R.. (2018) Palladium-Catalyzed Heck Cross-Coupling Reactions in Water: A Comprehensive Review. Catalysis letters, 148 (2). pp. 489-511. Szponarski, Mathieu and Schwizer, Fabian and Ward, Thomas R. and Gademann, Karl. (2018) On-cell catalysis by surface engineering of live cells with an artificial metalloenzyme. Communications Chemistry, 1 (84). pp. 1-10. Heinisch, Tillmann and Schwizer, Fabian and Garabedian, Brett and Csibra, Eszter and Jeschek, Markus and Vallapurackal, Jaicy and Pinheiro, Vitor B. and Marlière, Philippe and Panke, Sven and Ward, Thomas R.. (2018) E. coli surface display of streptavidin for directed evolution of an allylic deallylase. Chemical Science, 9 (24). pp. 5383-5388. Okamoto, Yasunori and Kojima, Ryosuke and Schwizer, Fabian and Bartolami, Eline and Heinisch, Tillmann and Matile, Stefan and Fussenegger, Martin and Ward, Thomas R.. (2018) A cell-penetrating artificial metalloenzyme regulates a gene switch in a designer mammalian cell. Nature Communications, 9. p. 1943. Zhao, Jingming and Rebelein, Johannes G. and Mallin, Hendrik and Trindler, Christian and Pellizzoni, Michela M. and Ward, Thomas R.. (2018) Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in Escherichia coli's Periplasm. Journal of American Chemical Society, 140 (41). pp. 13171-13175. Mallin, Hendrik and Ward, Thomas R.. (2018) Streptavidin-Enzyme Linked Aggregates for the One-Step Assembly and Purification of Enzyme Cascades. ChemCatChem, 10 (13). pp. 2810-2816. Mann, Samuel and Heinisch, Tillmann and Ward, Thomas R. and Borovik, A. S.. (2018) Coordination chemistry within a protein host: regulation of the secondary coordination sphere. Chemical Communications, 54 (35). pp. 4413-4416. Keller, Sascha G. and Probst, Benjamin and Heinisch, Tillmann and Alberto, Roger and Ward, Thomas R.. (2018) Photo-Driven Hydrogen Evolution by an Artificial Hydrogenase Utilizing the Biotin-Streptavidin Technology. Helvetica Chimica Acta, 101 (4). e1800036. Jeschek, Markus and Bahls, Maximilian O. and Schneider, Veronika and Marlière, Philippe and Ward, Thomas R. and Panke, Sven. (2017) Biotin-independent strains of Escherichia coli for enhanced streptavidin production. Metabolic Engineering, 40. pp. 33-40. Liu, Le and Cotelle, Yoann and Klehr, Juliane and Sakai, Naomi and Ward, Thomas R. and Matile, Stefan. (2017) Anion-π catalysis: Bicyclic products with four contiguous stereogenic centers from otherwise elusive diastereospecific domino reactions on π-acidic surfaces. Chemical Science, 8 (5). pp. 3770-3774. Trindler, Christian and Ward, Thomas R.. (2017) Artificial Metalloenzymes. In: Effects of Nanoconfinement on Catalysis, Fundamental and Applied Catalysis. Cham, Switzerland, pp. 49-82. Okamoto, Yasunori and Ward, Thomas R.. (2017) Cross-Regulation of an Artificial Metalloenzyme. Angewandte Chemie International Edition, 56 (34). pp. 10156-10160. Seck, Charlotte and Mbaye, Diagne M. and Coufourier, Sébastien and Lator, Alexis and Lohier, Jean-François and Poater, Albert and Ward, Thomas R. and Gaillard, Sylvain and Renaud, Jean-Luc. (2017) Alkylation of Ketones Catalyzed by Bifunctional Iron Complexes: From Mechanistic Understanding to Application. ChemCatChem, 9 (23). pp. 4410-4416. Okamoto, Yasunori and Ward, Thomas R.. (2017) Supramolecular Enzyme Mimics. In: Comprehensive Supramolecular Chemistry II, 4. Oxford, pp. 459-510. Okamoto, Yasunori and Ward, Thomas R.. (2017) Transfer Hydrogenation Catalyzed by Organometallic Complexes using NADH as Reductant in a Biochemical Context. Biochemistry, 56. pp. 5223-5224. Mann, Samuel and Heinisch, Tillmann and Ward, Thomas R. and Borovik, A. S.. (2017) Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins. Journal of the American Chemical Society, 139 (48). pp. 17289-17292. Keller, Sascha G. and Pannwitz, Andrea and Mallin, Hendrik and Wenger, Oliver S. and Ward, Thomas R.. (2017) Streptavidin as a Scaffold for Light-Induced Long-Lived Charge Separation. Chemistry - A European Journal, 23 (71). pp. 18019-18024. Cotelle, Yoann and Chuard, Nicolas and Lascano, Santiago and Lebrun, Vincent and Wehlauch, Robin and Bohni, Nadine and Loercher, Samuel and Postupalenko, Viktoriia and Reddy, Sai T. and Meier, Wolfgang and Palivan, Cornelia G. and Gademann, Karl and Ward, Thomas R. and Matile, Stefan. (2016) Interfacing Functional Systems. Chimia, 70 (6). pp. 418-423. Okamoto, Yasunori and Ward, Thomas R. and Wenger, Oliver S.. (2016) From Photodriven Charge Accumulation to Fueling Enzyme Cascades in Molecular Factories. Chimia, 70 (6). pp. 395-397. Keller, Sascha G. and Pannwitz, Andrea and Schwizer, Fabian and Klehr, Juliane and Wenger, Oliver S. and Ward, Thomas R.. (2016) Light-driven electron injection from a biotinylated triarylamine donor to [Ru(diimine)3]2+-labeled streptavidin. Organic and Biomolecular Chemistry, 14 (30). pp. 7197-7201. Liu, Zhe and Lebrun, Vincent and Kitanosono, Taku and Mallin, Hendrik and Köhler, Valentin and Häussinger, Daniel and Hilvert, Donald and Kobayashi, Shu and Ward, Thomas R.. (2016) Upregulation of an Artificial Zymogen by Proteolysis. Angewandte Chemie International Edition, 55 (38). pp. 11587-11590. Milopolska, Ewa and Kuss-Petermann, Martin and Neuburger, Markus and Wenger, Oliver and Ward, Thomas R.. (2016) N-Heterocyclic Carbene Ligands Bearing a Naphthoquinone Appendage: Synthesis and Coordination Chemistry. Polyhedron, 103. pp. 261-266. Mallin, Hendrik and Reuter, Raphael and Hestericova, Martina and Ward, Thomas R.. (2016) Library design and screening protocol for artificial metalloenzymes based on the biotin-streptavidin technology. Nature Protocols, 11. pp. 835-852. Mérel, Delphine S. and Gaillard, Sylvain and Ward, Thomas R. and Renaud , Jean-Luc. (2016) Achiral Cyclopentadienone Iron Tricarbonyl Complexes Embedded in Streptavidin: An Access to Artificial Iron Hydrogenases and Application in Asymmetric Hydrogenation. Catalysis Letters, 146 (3). pp. 564-569. Chatterjee, Anamitra and Ward, Thomas R.. (2016) Recent Advances in the Palladium Catalyzed Suzuki–Miyaura Cross-Coupling Reaction in Water. Catalysis Letters, 146 (4). pp. 820-840. Cotelle, Yoann and Benz, Sebastian and Avestro, Alyssa-Jennifer and Ward, Thomas R. and Sakai, Naomi and Matile, Stefan. (2016) Anion-π Catalysis of Enolate Chemistry: Rigidified Leonard Turns as a General Tool to Run Reactions on Aromatic Surfaces. Angewandte Chemie International Edition, 128 (13). pp. 4347-4351. Hyster, Todd K. and Ward, Thomas R.. (2016) Genetic Optimization of Metalloenzymes: Enhancing Enzymes for Non-Natural Reactions. Angewandte Chemie International Edition, 55 (26). pp. 7344-7357. Chatterjee, Anamitra and Mallin, Hendrik and Klehr, Juliane and Vallapurackal, Jaicy and Finke, Aaron D. and Vera, Laura and Marsh, May and Ward, Thomas R.. (2016) An Enantioselective Artificial Suzukiase Based on the Biotin–Streptavidin Technology. Chemical Science, 7 (1). pp. 673-677. Heinisch, Tillmann and Ward, Thomas R.. (2016) Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology: Challenges and Opportunities. Accounts of Chemical Research, 49 (9). pp. 1711-1721. Okamoto, Yasunori and Köhler, Valentin and Paul, Caroline E. and Hollmann, Frank and Ward, Thomas R.. (2016) Efficient In Situ Regeneration of NADH Mimics by an Artificial Metalloenzyme. ACS Catalysis, 6 (6). pp. 3553-3557. Ward, Thomas R.. (2016) Directed Evolution of Iridium-Substituted Myoglobin Affords Versatile Artificial Metalloenzymes for Enantioselective C−C Bond-Forming Reactions. Angewandte Chemie International Edition, 55 (48). pp. 14909-14911. Hestericova, Martina and Correro, M. Rita and Lenz, Markus and Corvini, Philippe F.-X. and Shahgaldian, Patrick and Ward, Thomas R.. (2016) Immobilization of an Artificial Imine Reductase within Silica Nanoparticles Improves its Performance. Chemical Communications , 52. pp. 9462-9465. Mann, Sam and Heinisch, Tillmann and Weitz, A. C. and Hendrich, M. R. and Ward, Thomas R. and Borovik, A. S. . (2016) Modular Artificial Cupredoxins. Journal of the American Chemical Society, 138 (29). pp. 9073-9076. Jeschek, Markus and Reuter, Raphael and Heinisch, Tillmann and Trindler, Christian and Klehr, Juliane and Panke, Sven and Ward, Thomas R.. (2016) Directed evolution of artificial metalloenzymes for in vivo metathesis. Nature, 537 (7622). pp. 661-665. Cotelle, Yoann and Lebrun, Vincent and Sakai, Naomi and Ward, Thomas R. and Matile, Stefan. (2016) Anion–π Enzymes. ACS Central Science, 2 (6). pp. 388-393. Okamoto, Yasunori and Köhler, Valentin and Ward, Thomas R.. (2016) An NAD(P)H-Dependent Artificial Transfer Hydrogenase for Multienzymatic Cascades. Journal of the American Chemical Society, 138 (18). pp. 5782-5784. Jeschek, Markus and Panke, Sven and Ward, Thomas R.. (2016) Periplasmic Screening for Artificial Metalloenzymes. Methods in enzymology, 580. pp. 539-556. Rottmann, Philipp and Ward, Thomas R. and Panke, Sven. (2016) Compartmentalization - A Prerequisite for Maintaining and Changing an Identity. Chimia, 70 (6). pp. 428-431. Fujieda, Nobutaka and Schätti, Jonas and Stuttfeld, Edward and Ohkubo, Kei and Maier, Timm and Fukuzumi, Shunichi and Ward, Thomas R.. (2015) Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding. Chemical Science, 6 (7). pp. 4060-4065. Heinisch, Tillmann and Pellizzoni, Michaela and Dürrenberger, Marc and Tinberg, Christine E. and Köhler, Valentin and Häussinger, Daniel and Klehr, Juliane and Baker, David and Ward, Thomas R.. (2015) Improving the catalytic performance of an artificial metalloenzyme by computational design. Journal of the American Chemical Society, 137 (32). pp. 10414-10419. Reuter, Raphael and Ward, Thomas R.. (2015) Profluorescent substrates for the screening of olefin metathesis catalysts. Beilstein journal of organic chemistry, 11. pp. 1886-1892. Heinisch, Tillmann and Ward, Thomas R.. (2015) Latest Developments in Metalloenzyme Design and Repurposing. European Journal of Inorganic Chemistry (21). pp. 3406-3418. Zhao, Jingming and Kajetanowicz, Anna and Ward, Thomas R.. (2015) Carbonic anhydrase II as host protein for the creation of a biocompatible artificial metathesase. Organic and Biomolecular Chemistry, 13 (20). pp. 5652-5655. Quinto, Tommaso and Köhler, Valentin and Häussinger, Daniel and Ward, Thomas R.. (2015) Artificial metalloenzymes for the diastereoselective reduction of NAD+ to NAD2H. Organic and Biomolecular Chemistry, 13. pp. 357-360. Wilson, Yvonne M. and Dürrenberger, Marc and Nogueira, Elisa S. and Ward, Thomas R.. (2014) Neutralizing the Detrimental Effect of Glutathione on Precious Metal Catalysts. Journal of the American Chemical Society, 136 (25). pp. 8928-8932. Munoz-Robles, Victor and Vidossich, Pietro and Lledos, Agustí and Ward, Thomas R. and Maréchal, Jean-Didier. (2014) Computational Insights on an Artificial Imine Reductase Based on the Biotin–Streptavidin Technology. ACS Catalysis, 4 (3). pp. 833-842. Munoz-Robles, Victor and Dürrenberger, Marc and Tillmann, Heinisch and Lledos, Agustí and Schirmer, Tilman and Ward, Thomas R. and Maréchal, Jean-Didier. (2014) Structural, Kinetic, and Docking Studies of Artificial Imine Reductases Based on Biotin–Streptavidin Technology: An Induced Lock-and-Key Hypothesis. Journal of the American Chemical Society, 136 (44). pp. 15676-15683. Quinto, Tommaso and Köhler, Valentin and Ward, Thomas R.. (2014) Recent Trends in Biomimetic NADH Regeneration. Topics in catalysis, 57 (5). p. 321. Quinto, Tommaso and Schwizer, Fabian and Zimbron, Jeremy M. and Morina, Albert and Köhler, Valentin and Ward, Thomas R.. (2014) Expanding the Chemical Diversity in Artificial Imine Reductases Based on the Biotin-Streptavidin Technology. ChemCatChem, 6 (4). pp. 1010-1014. Nogueira, Elisa S. and Schleier, Thomas and Dürrenberger, Marc and Ballmer-Hofer, Kurt and Ward, Thomas R. and Jaussi, Rolf. (2014) High-level secretion of recombinant full-length streptavidin in Pichia pastoris and its application to enantioselective catalysis. Protein Expression and Purification, 93. pp. 54-63. Genz, Maika and Köhler, Valentin and Krauss, Michael and Singer, David and Hoffmann, Ralf and Ward, Thomas R. and Sträter, Norbert. (2014) An Artificial Imine Reductase Based on the RNAse S Scaffold. ChemCatChem, 6 (3). pp. 736-740. Dürrenberger, Marc and Ward, Thomas R.. (2014) Recent Achievments in the Design and Engineering of Artificial Metalloenzymes. Current Opinion in Chemical Biology, 19. pp. 99-106. Kajetanowicz, Anna and Chatterjee, Anamitra and Reuter, Raphael and Ward, Thomas R.. (2014) Biotinylated Metathesis Catalysts: Synthesis and Performance in Ring Closing Metathesis. Catalysis Letters, 144 (3). pp. 373-379. Keller, Sascha G. and Ringenberg, Mark R. and Häussinger, Daniel and Ward, Thomas R.. (2014) Evaluation of the Formate Dehydrogenase Activity of Three-Legged Pianostool Complexes in Dilute Aqueous Solution. European Journal of Inorganic Chemistry, 2014 (34). pp. 5860-5864. Reuter, Raphael and Ward, Thomas R.. (2014) D(+)-Biotin. In: e-EROS Encyclopedia of Reagents for Organic Synthesis. London, UK, pp. 1-4. Koehler, V. and Wilson, Y. M. and Duerrenberger, M. and Ghislieri, D. and Churakova, E. and Quinto, T. and Knoerr, L. and Haeussinger, D. and Hollmann, F. and Turner, N. J. and Ward, Thomas R.. (2013) Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes. Nature Chemistry, 5. pp. 93-99. Zimbron, Jeremy M. and Heinisch, Tillmann and Schmid, Maurus and Hamels, Didier and Nogueira, Elisa S. and Schirmer, Tilman and Ward, Thomas R.. (2013) A Dual Anchoring Strategy for the Localization and Activation of Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology. Journal of the American Chemical Society, 135 (14). pp. 5384-5388. Heinisch, Tillmann and Langowska, Karolina and Tanner, Pascal and Reymond, Jean-Louis and Meier, Wolfgang and Palivan, Cornelia and Ward, Thomas R.. (2013) Fluorescence-Based Assay for the Optimization of the Activity of Artificial Transfer Hydrogenase within a Biocompatible Compartment. ChemCatChem, 5 (3). pp. 720-723. Monnard, Fabien W. and Nogueira, Elisa S. and Heinisch, Tillmann and Schirmer, Tilman and Ward, Thomas R.. (2013) Human Carbonic Anhydrase II as Host Protein for the Creation of Artificial Metalloenzymes : the Asymmetric Transfer Hydrogenation of Imines. Chemical Science, 4 (6). p. 3269. Bereau, Tristan and Kramer, Christian and Monnard, Fabien W. and Nogueira, Elisa S. and Ward, Thomas R. and Meuwly, Markus. (2013) Scoring Multipole Electrostatics in Condensed-Phase Atomistic Simulations. Journal of Physical Chemistry B, 117 (18). pp. 5460-5471. Schwizer, Fabian and Köhler, Valentin and Dürrenberger, Marc and Knörr, Livia and Ward, Thomas R.. (2013) Genetic Optimization of the Catalytic Efficiency of Artificial Imine Reductases Based on the Biotin-Streptavidin Technology. ACS Catalysis, 3 (8). pp. 1752-1755. Schmid, Maurus H. and Ward, Thomas R. and Meuwly, Markus. (2013) Towards a Broadly Applicable Force Field for d6-piano Stool Complexes. Journal of Chemical Theory and Computation, 9 (5). pp. 2313-2323. Praneeth, Vijayendran Koombil Kummaya and Ward, Thomas R.. (2013) Metal-Catalyzed Organic Transformations Inside a Protein Scaffold Using Artificial Metalloenzymes. In: Coordination Chemistry in Protein Cages: Principles, Design, and Applications, 8. pp. 203-220. Hamels, Didier R. and Ward, Thomas R.. (2013) Biomacromolecules as Ligands for Artificial Metalloenzymes. In: Comprehensive Inorganic Chemistry II , 6: Homogeneous Catalytic Applications. pp. 737-761. Ward, Thomas R.. (2013) Author Profile: Thomas Ward. Angewandte Chemie International Edition, 52 (18). p. 4722. Schmid, Maurus and Nogueira, Elisa S. and Monnard, Fabien W. and Ward, Thomas R. and Meuwly, Markus. (2012) Arylsulfonamides as Inhibitors for Carbonic Anhydrase : Prediction & Validation. Chemical Science, 3 (3). pp. 690-700. Praneeth, Vijayendran K. K. and Ringenberg, Mark R. and Ward, Thomas R.. (2012) Redox-Active Ligands in Catalysis. Angewandte Chemie International Edition, 51 (41). pp. 10228-10234. Amrein, Beat and Schmid, Maurus and Collet, Guillaume and Cuniasse, Philippe and Gilardoni, Francois and Seebeck, Florian P. and Ward, Thomas R.. (2012) Identification of two-histidines one-carboxylate binding motifs in proteins amenable to facial coordination to metals. Metallomics, 4 (4). pp. 379-388. Oohora, Koji and Burazerovic, Sabina and Onoda, Akira and Wilson, Yvonne M. and Ward, Thomas R. and Hayashi, Takashi. (2012) Chemically Programmed Supramolecular Assembly of Hemoprotein and Streptavidin with Alternating Alignment. Angewandte Chemie International Edition, 51 (16). pp. 3818-3821. Hyster, Todd K. and Knoerr, Livia and Ward, Thomas R. and Rovis, Tomislav. (2012) Biotinylated Rh(III) complexes in engineered streptavidin for accelerated asymmetric C-H activation. Science, 338 (6106). pp. 500-503. Ward, Thomas R. and Pordea, Anca. (2012) Enantioselective Hybrid Catalysts. In: Comprehensive Chirality: Synthetic Methods , VI Enzymatic and Semi-Enzymatic. Amsterdam, pp. 516-552. Monnard, Fabien W. and Heinisch, Tillmann and Nogueira, Elisa S. and Schirmer, Tilman and Ward, Thomas R.. (2011) Human Carbonic Anhydrase II as a host for piano-stool complexes bearing a sulfonamide anchor. Chemical Communications, 47 (29). pp. 8238-8240. Sardo, Alessia and Wohlschlager, Therese and Lo, Cheikh and Zoller, Heinz and Ward, Thomas R. and Creus, Marc. (2011) Burkavidin: A novel secreted biotin-binding protein from the human pathogen Burkholderia pseudomallei. Protein Expression and Purification, 77 (2). pp. 131-139. Ringenberg, Mark and Ward, Thomas R.. (2011) Merging the Best of Two Worlds : Artificial Metalloenzymes for Enantioselective Catalysis. Chemical Communications, 47, (30). pp. 8470-8476. Köhler, Valentin and Mao, Jincheng and Heinisch, Tillmann and Pordea, Anca and Sardo, Alessia and Wilson, Yvonne and Knörr, Livia and Creus, Marc and Prost, Jean-Christophe and Schirmer, Tilman and Ward, Thomas R.. (2011) OsO4⋅Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis-Dihydroxylation of Olefins. Angewandte Chemie International Edition, 50 (46). pp. 10863-10866. Clemens, M. and Gillingham, Dennis and Ward, Thomas R. and Hilvert, Donald. (2011) An Artificial Metalloenzyme for Olefin Metathesis. Journal of the Chemical Society, Chemical Communications, 47 (44). pp. 12068-12070. Ward, Thomas R.. (2011) Artificial Metalloenzymes Based on the Biotin-Avidin Technology : Enantio-selective Catalysis and Beyond. Accounts of Chemical Research, 44 (1). pp. 47-57. Dürrenberger, Marc and Heinisch, Tillmann and Wilson, Yvonne and Rossel, Thibaud and Nogueira, Elisa and Knörr, Livia and Mutschler, Annette and Kersten, Karoline and Zimbron, Mallcom and Pierron, Julien and Schirmer, Tilman and Ward, Thomas R.. (2011) Artificial Transfer Hydrogenases for the Enantioselective Reduction of Cyclic Imines. Angewandte Chemie International Edition, 50 (13). pp. 3026-3029. Creus, Marc and Ward, Thomas R.. (2011) Design and Evolution of Artificial Metalloenzymes: Biomimetic Aspects. Progress In Inorganic Chemistry, 57. pp. 203-254. Lo, Cheikh and Ringenberg, Mark and Gnandt, David and Wilson, Yvonne and Ward, Thomas R.. (2011) Artificial metalloenzymes for olefin metathesis based on the biotin-(strept)avidin technology. Chemical Communications, 47 (44). pp. 12065-12067. Zimbron, Jeremy M. and Sardo, Alessia and Heinisch, Tillmann and Wohlschlager, Therese and Gradinaru, Julieta and Massa, Claudia and Schirmer, Tilman and Creus, Marc and Ward, Thomas R.. (2010) Chemo-Genetic Optimization of DNA Recognition by Metallodrugs using a Presenter-Protein Strategy. Chemistry - A European Journal, 16 (43). pp. 12883-12889. Pordea, Anca and Creus, Marc and Letondor, Christophe and Ivanova, Anita and Ward, Thomas R.. (2010) Improving the enantioselectivity of artificial transfer hydrogenases based on the biotin-streptavidin technology by combinations of point mutations. Inorganica Chimica Acta, 363 (3). pp. 601-604. Köhler, Valentin and Ward, Thomas R.. (2010) Design of a Functional Nitric Oxide Reductase within a Myoglobin Scaffold. Chembiochem : a European journal of chemical biology, 118 (8). pp. 81049-81051. Heinisch, Tillmann and Ward, Thomas R.. (2010) Design strategies for the creation of artificial metalloenzymes. Current Opinion in Chemical Biology, 14 (2). pp. 184-199. Panek, Jaroslaw J. and Ward, Thomas R. and Jezierska-Mazzarello, Aneta and Novic, Marjana. (2010) Flexibility of a biotinylated ligand in artificial metalloenzymes based on streptavidin-an insight from molecular dynamics simulations with classical and ab initio force fields. Journal of Computer-Aided Molecular Design, 24 (9). pp. 719-732. Mao, Jincheng and Ward, Thomas R.. (2010) Proteins as Host for Enantioselective Catalysis: Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology. In: Molecular Encapsulation: Organic Reactions in Constrained Systems. Chichester, pp. 361-376. Köhler, Valentin and Wilson, Yvonne M. and Lo, Cheikh and Sardo, Alessia and Ward, Thomas R.. (2010) Protein-based hybrid catalysts—design and evolution. Current Opinion in Biotechnology, 21 (6). pp. 744-752. Panek, Jaroslaw J. and Ward, Thomas R. and Jezierska, Aneta and Novic, Marjana. (2009) Effects of tryptophan residue fluorination on streptavidin stability and biotin-streptavidin interactions via molecular dynamics simulations. Journal of Molecular Modeling, 15 (3). pp. 257-266. Pordea, A. and Mathis, D. and Ward, Thomas R.. (2009) IIncorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation. Journal of Organometallic Chemistry, 694 (6). pp. 930-936. Fuerstenberg, Alexandre and Kel, Oksana and Gradinaru, Julieta and Ward, Thomas R. and Emery, Daniel and Bollot, Guillaume and Mareda, Jiri and Vauthey, Eric. (2009) Site-Dependent Excited-State Dynamics of a Fluorescent Probe Bound to Avidin and Streptavidin. ChemPhysChem, 10 (9/10). pp. 1517-1532. Pordea, Anca and Ward, Thomas R.. (2009) Artificial metalloenzymes : combining the best features of homogeneous and enzymatic catalysis. Synlett, 2009 (16). pp. 3225-3236. Pordea, Anca and Creus, Marc and Panek, Jaroslaw and Duboc, Carole and Mathis, Deborah and Novic, Marjana and Ward, Thomas R.. (2008) Artificial metalloenzyme for enantioselective sulfoxidation based on vanadyl-loaded streptavidin. Journal of the American Chemical Society, 130 (25). pp. 8085-8088. Mao, Jincheng and Ward, Thomas R.. (2008) Artificial metalloenzymes for enantioselective catalysis based on the biotin-avidin technology. Chimia, 62 (12). pp. 956-961. Steinreiber, Johannes and Ward, Thomas R.. (2008) Artificial metalloenzymes as selective catalysts in aqueous media. Coordination Chemistry Reviews, 252 (5-7). pp. 751-766. Creus, Marc and Pordea, Anca and Rossel, Thibaud and Sardo, Alessia and Letondor, Christophe and Ivanova, Anita and LeTrong, Isolde and Stenkamp, Ronald E. and Ward, Thomas R.. (2008) X-ray structure and designed evolution of an artificial transfer hydrogenase. Angewandte Chemie International Edition, 47 (8). pp. 1400-1404. Han, Anpan and Creus, Marc and Schuermann, Gregor and Linder, Vincent and Ward, Thomas R. and de Rooij, Nico F. and Staufer, Urs. (2008) Label-free detection of single protein molecules and protein-protein interactions using synthetic nanopores. Analytical Chemistry, 80 (12). pp. 4651-4658. Ward, Thomas R.. (2008) Artificial enzymes made to order : combination of computational design and directed evolution. Angewandte Chemie International Edition, 47 (41). pp. 7802-7803. Pierron, Julien and Malan, Christophe and Creus, Marc and Gradinaru, Julieta and Hafner, Ines and Ivanova, Anita and Sardo, Alessia and Ward, Thomas R.. (2008) Artificial metalloenzymes for asymmetric allylic alkylation on the basis of the biotin-avidin technology. Angewandte Chemie International Edition, 47 (4). pp. 701-705. Pordea, Anca and Ward, Thomas R.. (2008) Chemogenetic protein engineering : an efficient tool for the optimization of artificial metalloenzymes. Chemical Communications, 44 (36). pp. 4239-4249. Humbert, Nicolas and Ward, Thomas R.. (2008) Functionality screen of streptavidin mutants by non-denaturing SDS-PAGE using biotin-4-fluorescein. In: Avidin-Biotin Interactions: Methods and Applications, 418. Totowa, NJ 07512 USA, pp. 63-71. Humbert, Nicolas and Schormann, Peter and Zocchi, Andrea and Neuhaus, Jean-Marc and Ward, Thomas R.. (2008) High-yield production and purification of recombinant T7-tag mature streptavidin in glucose-stressed E-coli. In: Avidin-Biotin Interactions: Methods and Applications, 418. Totowa, NJ, pp. 101-110. Rusbandi, Untung E. and Skander, Myriem and Ivanova, Anita and Malan, Christophe and Ward, Thomas R.. (2007) Second-generation artificial hydrogenases based on the biotin–avidin technology: Improving selectivity and organic solvent tolerance by introduction of an (R)-proline spacer. Comptes Rendus Chimie, 10 (8). pp. 678-683. Mazurek, Sylwester and Ward, Thomas R. and Novic, Marjana. (2007) Counter propagation artificial neural networks modeling of an enantioselectivity of artificial metalloenzymes. Molecular Diversity, 11 (3-4). pp. 141-152. Rusbandi, Untung E. and Lo, Cheikh and Skander, Myriem and Ivanova, Anita and Creus, Marc and Humbert, Nicolas and Ward, Thomas R.. (2007) Second Generation Artificial Hydrogenases Based on the Biotin-Avidin Technology: Improving Activity, Stability and Selectivity by Introduction of Enantiopure Amino Acid Spacers. Advanced Synthesis and Catalysis, 349 (11/12). pp. 1923-1930. Burazerovic, Sabina and Gradinaru, Julieta and Pierron, Julien and Ward, Thomas R.. (2007) Hierarchical self-assembly of one-dimensional streptavidin bundles as a collagen mimetic for the biomineralization of calcite. Angewandte Chemie International Edition, 46 (29). pp. 5510-5514. Creus, Marc and Ward, Thomas R.. (2007) Designed evolution of artificial metalloenzymes: Protein catalysts made to order. Organic and Biomolecular Chemistry, 5 (12). pp. 1835-1844. Le Trong, Isolde and Humbert, Nicolas and Ward, Thomas R. and Stenkamp, Ronald E.. (2006) Crystallographic Analysis of a Full-length Streptavidin with Its C-terminal Polypeptide Bound in the Biotin Binding Site. Journal of Molecular Biology, 356 (3). pp. 738-745. Loosli, Andreas and Rusbandi, Untung Edy and Gradinaru, Julieta and Bernauer, Klaus and Schlaepfer, Carl Wilhelm and Meyer, Michel and Mazurek, Sylwester and Novic, Marjana and Ward, Thomas R.. (2006) (Strept)avidin as Host for Biotinylated Coordination Complexes: Stability, Chiral Discrimination, and Cooperativity. Inorganic Chemistry, 45 (2). pp. 660-668. Delahaye, Sandra and Loosli, Claudia and Liu, Shi-Xia and Decurtins, Silvio and Labat, Gael and Neels, Antonia and Loosli, Andreas and Ward, Thomas R. and Hauser, Andreas. (2006) Inter- and Intramolecular Interactions in Some Supramolecular Photochemical Systems. Advanced Functional Materials, 16 (2). pp. 286-295. Letondor, Christophe and Ward, Thomas R.. (2006) Artificial Metalloenzymes for Enantioselective Catalysis: Recent Advances. ChemBioChem, 7 (12). pp. 1845-1852. Letondor, Christophe and Pordea, Anca and Humbert, Nicolas and Ivanova, Anita and Mazurek, Sylwester and Novic, Marjana and Ward, Thomas R.. (2006) Artificial transfer hydrogenases based on the biotin-(strept)avidin technology : fine tuning the selectivity by saturation mutagenesis of the host protein. Journal of the American Chemical Society, 128 (25). pp. 8320-8328. Humbert, Nicolas and Zocchi, Andrea and Ward, Thomas R.. (2005) Electrophoretic behavior of streptavidin complexed to a biotinylated probe: A functional screening assay for biotin-binding proteins. Electrophoresis, 26 (1). pp. 47-52. Vieille-Petit, Ludovic and Suess-Fink, Georg and Therrien, Bruno and Ward, Thomas R. and Stoeckli-Evans, Helen and Labat, Gaeel and Karmazin-Brelot, Lydia and Neels, Antonia and Buergi, Thomas and Finke, Richard G. and Hagen, Collin M.. (2005) Synthesis and Characterization of Tetrahedral Ru3O Clusters with Intrinsic Framework Chirality: A Chiral Probe of the Intact Cluster Catalysis Concept. Organometallics, 24 (25). pp. 6104-6119. Klein, Gerard and Humbert, Nicolas and Gradinaru, Julieta and Ivanova, Anita and Gilardoni, Francois and Rusbandi, Untung E. and Ward, Thomas R.. (2005) Tailoring the Active Site of Chemzymes by Using a Chemogenetic-Optimization Procedure: Towards Substrate-Specific Artificial Hydrogenases Based on the Biotin–Avidin Technology. Angewandte Chemie International Edition, 44 (47). pp. 7764-7767. Thomas, Christophe M. and Letondor, Christophe and Humbert, Nicolas and Ward, Thomas R.. (2005) Aqueous oxidation of alcohols catalyzed by artificial metalloenzymes based on the biotin-avidin technology. Journal of Organometallic Chemistry, 690 (20). pp. 4488-4491. Thomas, Christophe M. and Ward, Thomas R.. (2005) Design of artificial metalloenzymes. Applied Organometallic Chemistry, 19 (1). pp. 35-39. Ward, Thomas R.. (2005) Artificial Metalloenzymes for Enantioselective Catalysis Based on the Noncovalent Incorporation of Organometallic Moieties in a Host Protein. Chemistry - A European Journal, 11 (13). pp. 3798-3804. Skander, Myriem and Malan, Christophe and Ivanova, Anita and Ward, Thomas R.. (2005) Chemical optimization of artificial metalloenzymes based on the biotin-avidin technology : (S)-selective and solvent-tolerant hydrogenation catalysts via the introduction of chiral amino acid spacers. Chemical Communications, 41 (38). pp. 4815-4817. Letondor, Christophe and Humbert, Nicolas and Ward, Thomas R.. (2005) Artificial metalloenzymes based on biotin-avidin technology for the enantioselective reduction of ketones by transfer hydrogenation. Proceedings of the National Academy of Sciences, 102 (13). pp. 4683-4687. Thomas, Christophe M. and Ward, Thomas R.. (2005) Artificial metalloenzymes: proteins as hosts for enantioselective catalysis. Chemical Society Reviews, 34 (4). pp. 337-346. Skander, Myriem and Humbert, Nicolas and Collot, Jerome and Gradinaru, Julieta and Klein, Gerard and Loosli, Andreas and Sauser, Jerome and Zocchi, Andrea and Gilardoni, Francois and Ward, Thomas R.. (2004) Artificial Metalloenzymes: (Strept)avidin as Host for Enantioselective Hydrogenation by Achiral Biotinylated Rhodium−Diphosphine Complexes. Journal of the American Chemical Society, 126 (44). pp. 14411-14418. Collot, Jerome and Humbert, Nicolas and Skander, Myriem and Klein, Gerard and Ward, Thomas R.. (2004) Artificial metalloenzymes for enantioselective catalysis : the phenomenon of protein accelerated catalysis. Journal of Organometallic Chemistry, 689 (25). pp. 4868-4871. Suss-Fink, Georg and Therrien, Bruno and Vieille-Petit, Ludovic and Tschan, Mathieu and Romakh, Vladimir B. and Ward, Thomas R. and Dadras, Massoud and Laurenczy, Gabor. (2004) Supramolecular cluster catalysis: facts and problems. Journal of Organometallic Chemistry, 689 (8). pp. 1362-1369. Vieille-Petit, Ludovic and Therrien, Bruno and Suss-Fink, Georg and Ward, Thomas R.. (2004) Erratum to “Isolation and single-crystal X-ray structure analysis of the catalyst-substrate host–guest complexes [C6H6⊂H3Ru3{C6H5(CH2)nOH}(C6Me6)2(O)]+ (n=2,3)” [J. Organomet. Chem. 684 (2003) 117–123]. Journal of Organometallic Chemistry, 689 (1). p. 271. Ward, Thomas R. and Collot, Jerome and Gradinaru, Julieta and Loosli, Andreas and Skander, Myriem and Letondor, Christophe and Joseph, Edith and Klein, Gerard. (2003) Exploiting the second coordination sphere : proteins as host for enantioselective catalysis. Chimia, 57 (10). pp. 586-588. Zocchi, Andrea and Humbert, Nicolas and Berta, Temugin and Ward, Thomas R.. (2003) Efficient expression and mutation of avidin and streptavidin as host proteins for enantioselective catalysis. Chimia, 57 (10). pp. 589-592. Collot, Jerome and Gradinaru, Julieta and Humbert, Nicolas and Skander, Myriem and Zocchi, Andrea and Ward, Thomas R.. (2003) Artificial metalloenzymes for enantioselective catalysis based on biotin-avidin. Journal of the American Chemical Society, 125 (30). pp. 9030-9031. Vieille-Petit, Ludovic and Therrien, Bruno and Suss-Fink, Georg and Ward, Thomas R.. (2003) Isolation and single-crystal X-ray structure analysis of the catalyst–substrate host–guest complexes [C6H6⊂H3Ru3{C6H5(CH2)nOH}(C6Me6)2(O)]+ (n=2, 3). Journal of Organometallic Chemistry, 684 (1/2). pp. 117-123. Zocchi, Andrea and Marya Jobe, Anna and Neuhaus, Jean-Marc and Ward, Thomas R.. (2003) Expression and purification of a recombinant avidin with a lowered isoelectric point in Pichia pastoris. Protein Expression and Purification, 32 (2). pp. 167-174. Suss-Fink, Georg and Faure, Matthieu and Ward, Thomas R.. (2002) Supramolecular Cluster Catalysis: Benzene Hydrogenation Catalyzed by a Cationic Triruthenium Cluster under Biphasic Conditions. Angewandte Chemie International Edition, 41 (1). pp. 99-101. Laurenczy, Gabor and Faure, Matthieu and Vieille-Petit, Ludovic and Suss-Fink, Georg and Ward, Thomas R.. (2002) Mechanistic in situ High-Pressure NMR Studies of Benzene Hydrogenation by Supramolecular Cluster Catalysis with [(η6-C6H6)(η6-C6Me6)2Ru3(μ3-O)(μ2-OH)(μ2-H)2][BF4]. Advanced Synthesis and Catalysis, 344 (10). pp. 1073-1077. Duclos, Severine and Stoeckli-Evans, Helen and Ward, Thomas R.. (2001) Design and Synthesis of Compartmental Ligands and their Complexes for the Production of Catalytic Antibodies. Helvetica Chimica Acta, 84 (10). pp. 3148-3161. Braendli, Christof and Ward, Thomas R.. (2000) A Versatile Approach to the Solution-Phase Combinatorial Synthesis of Substituted Pyridines: The Cobalt-Catalyzed Cyclotrimerization of Alkynes with a Nitrile. Journal of Combinatorial Chemistry, 2 (1). pp. 42-47. Ward, Thomas R.. (1999) From catalyst design to molecular devices : theory and experiments. Chimia, 53 (1/2). pp. 19-28. Ward, Thomas R. and Lutz, Andreas and Parel, Serge P. and Ensling, Juergen and Guetlich, Philipp and Buglyo, Peter and Orvig, Chris. (1999) An Iron-Based Molecular Redox Switch as a Model for Iron Release from Enterobactin via the Salicylate Binding Mode. Inorganic Chemistry, 38 (22). pp. 5007-5017. Therrien, Bruno and Koenig, Adrian and Ward, Thomas R.. (1999) Synthesis of a Configurationally Stable Three-Legged Piano-Stool Complex. Organometallics, 18 (8). pp. 1565-1568. Therrien, Bruno and Ward, Thomas R.. (1999) Synthesis of a Configurationally Stable Three-Legged Piano-Stool Complex. Angewandte Chemie International Edition, 38 (3). pp. 405-408. Gilardoni, F. and Weber, J. and Chermette, H. and Ward, Thomas R.. (1998) Reactivity Indices in Density Functional Theory: A New Evaluation of the Condensed Fukui Function by Numerical Integration. Journal of Physical Chemistry B, 102 (20). pp. 3607-3613. Braendli, Christof and Ward, Thomas R.. (1998) Libraries via Metathesis of Internal Olefins. Helvetica Chimica Acta, 81 (9). pp. 1616-1621. Lutz, Andreas and Ward, Thomas R.. (1998) Tripodal dodecadentate ligands with salicylamide and bipyridine binding sites for iron(II) and iron(III) coordination. Helvetica Chimica Acta, 81 (2). pp. 207-218. Therrien, Bruno and Ward, Thomas R. and Pilkington, Melanie and Hoffmann, Christina and Gilardoni, Francois and Weber, Jacques. (1998) Synthesis and Reactivity of Tethered η1:η6-(Phosphinoarene)ruthenium Dichlorides. Organometallics, 17 (3). pp. 330-337. Ward, Thomas R. and Duclos, Severine and Therrien, Bruno and Schenk, Kurt. (1998) Coordination Properties of Klaeui's Tripodal Oxygen Donor toward Zirconium(IV). Organometallics, 17 (12). pp. 2490-2494. Ward, Thomas R.. (1997) Electronic asymmetry : theoretical background, ligand design, and applications. Chimia, 51 (5). pp. 238-240. Ward, Thomas R. and Buergi, Hans-Beat and Gilardoni, Francois and Weber, Jacques. (1997) Edge-Bridged Tetrahedral Geometry of Five-Coordinate d0 Complexes, Relatives of the Bent [MCp2L3] Family: A Theoretical and Structure-Correlation Study. Journal of the American Chemical Society, 119 (49). pp. 11974-11985. Ward, Thomas R. and Schafer, Olivier and Daul, Claude and Hofmann, Peter. (1997) Geometry of Coordinatively Unsaturated Two-Legged Piano Stool Complexes with 16 Valence Electrons: A Theoretical Study. Organometallics, 16 (14). pp. 3207-3215. Lutz, Andreas and Ward, Thomas R. and Albrecht, Martin. (1996) Synthesis of salicylamide and bipyridine containing ligands for iron(II) and iron(III) coordination. Tetrahedron, 52 (37). pp. 12197-12208. Ward, Thomas R.. (1996) Regioselectivity of Nucleophilic Attack on [Pd(allyl)(phosphine)(imine)] Complexes: A Theoretical Study. Organometallics, 15 (12). pp. 2836-2838. Giannini, Luca and Solari, Euro and De Angelis, Stefania and Ward, Thomas R. and Floriani, Carlo and Chiesi-Villa, Angiola and Rizzoli, Corrado. (1995) Migratory aptitude of the Zr-C functionalities bonded to a macrocyclic structure : thermally- and solvent-assisted intra- and intermolecular migrations in dialkyl(dibenzotetramethyltetraazaannulene)zirconium(IV). Journal of the American Chemical Society, Vol. 117, H. 21. pp. 5801-5811. Ward, Thomas R. and Alemany, Pere and Hoffmann, Roald. (1994) Adhesion of Rh, Pd, and Pt to Alumina and NO Reactions on Resulting Surfaces. ACS Symposium Series, 552. pp. 140-156. Ward, Thomas R. and Alemany, Pere and Hoffmann, Roald. (1993) Adhesion of rhodium, palladium, and platinum to alumina and the reduction of nitric oxide on the resulting surfaces: a theoretical analysis. The Journal of physical chemistry, 97 (29). pp. 7691-7699. Ward, Thomas R. and Hoffmann, Roald and Shelef, Mordecai. (1993) Coupling nitrosyls as the first step in the reduction of NO on metal surfaces : the special role of rhodium. Surface science, Vol. 289, H. 1/2. pp. 85-99. Ward, Thomas R. and Venanzi, Luigi M. and Albinati, Alberto and Lianza, Francesca and Gerfin, Tobias and Gramlich, Volker and Ramos Tombo, Gerardo M.. (1991) Synthesis and x-ray crystal structure of an optically pure tripodal C3-symmetric tritertiary phosphine bearing chirality on phosphorus. Helvetica Chimica Acta, Vol. 74, fasc. 5. pp. 983-988. Imhof, Daniel and Rueegger, Heinz and Venanzi, Luigi M. and Ward, Thomas R.. (1991) Solution structure of [(triphos*)RhH2(AuPPh3)3][PF6]2 deduced by one- and two-dimensional 1H{31P} and 1H{103Rh} double-resonance techniques. Magnetic resonance in chemistry, Vol. 29, Spec. Issue. pp. 73-79. Ott, J. and Schmid, B. and Venanzi, L. M. and Wang, G. and Ward, T. R. and Tombo, G. M. R.. (1990) Rhodium Phosphine Complexes as Acetalization Catalysts. New Journal of Chemistry, 14 (6-7). pp. 495-498. Ott, J. and Ramos Tombo, G. M. and Schmid, B. and Venanzi, L. M. and Wang, G. and Ward, Thomas R.. (1989) A versatile rhodium catalyst for acetalization reactions under mild conditions. Tetrahedron Letters, 30 (45). pp. 6151-6154. Cornioley-Deuschel, Christine and Ward, Thomas R. and Von Zelewsky, Alex. (1988) Complexes with pincers : 2,6-Diphenylpyridine as twofold-deprotonated terdentate ligand in C,C-trans-, and as mono-deprotonated chelate ligand in chiral C,C-cis-complexes of platinum(II) and palladium(II). Helvetica Chimica Acta, 71 (1). pp. 130-133. |