A visible-light promoted amine oxidation catalyzed by a Cp*Ir complex

Davis, Holly Jane and Häussinger, Daniel and Ward, Thomas R. and Okamoto, Yasunori. (2020) A visible-light promoted amine oxidation catalyzed by a Cp*Ir complex. ChemCatChem, 12 (18). pp. 4512-4516.

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Through a rapid screening of Cp*Ir complexes based on a turn-on type fluorescence readout, a [Cp*Ir(dipyrido[3,2-a:2',3'-c]phenazine)Cl] + complex was found to catalyze the blue-light promoted dehydrogenation of N -heterocycles under physiological conditions. In the dehydrogenation of tetrahydroisoquinolines, the catalyst preferentially yielded the monodehydrogenated product, accompanying H 2 O 2 generation. We surmise that this mechanism may be reminiscent of flavin-dependent oxidases.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Bioanorganische Chemie (Ward)
UniBasel Contributors:Ward, Thomas R. R. and Häussinger, Daniel
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:12 Apr 2021 07:03
Deposited On:23 Sep 2020 08:37

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