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Items where Author is "Schier , Alexander F."

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Number of items: 130.

2022

Sfeir, Agnel and Fishell, Gord and Schier, Alexander F. and Dustin, Michael L. and Gan, Wen-Biao and Joyner, Alexandra and Lehmann, Ruth and Ron, David and Roth, David and Talbot, William S. and Yelon, Deborah and Zychlinsky, Arturo. (2022) Basic science under threat: Lessons from the Skirball Institute. Cell, 185 (5). pp. 755-758.

Shafer, Shafer, Maxwell Eric Robert and Sawh, Ahilya N. and Schier, Alexander F.. (2022) Gene family evolution underlies cell type diversification in the hypothalamus of teleosts. Nature ecology & evolution, 6 (1). pp. 63-76.

25 April 2021

Dingal, P. C. Dave P. and Carte, Adam N. and Montague, Tessa C. and Schier, Alexander F.. (2021) Regulation of Vg1 biogenesis during mesendoderm induction.

16 April 2021

Abitua, Philipp B. and Aksel, Deniz C. and Schier, Alexander F.. (2021) Axis formation in annual killifish: Nodal coordinates morphogenesis in absence of Huluwa prepatterning.

11 January 2021

Shafer, Maxwell E. R. and Sawh, Ahilya N. and Schier, Alexander F.. (2021) Gene family evolution underlies cell type diversification in the hypothalamus of teleosts.

2021

Lord, Nathan D. and Carte, Adam N. and Abitua, Philip B. and Schier, Alexander F.. (2021) The pattern of nodal morphogen signaling is shaped by co-receptor expression. eLife, 10. p. 54894.

2020

Raj, Bushra and Farrell, Jeffrey A. and Liu, Jialin and El Kholtei, Jakob and Carte, Adam N. and Navajas Acedo, Joaquin and Du, Lucia Y. and McKenna, Aaron and Relić, Đorđe and Leslie, Jessica M. and Schier, Alexander F.. (2020) Emergence of Neuronal Diversity during Vertebrate Brain Development. Neuron, 108 (6). pp. 1058-1074.e6.

Schier, Alexander F.. (2020) Single-cell biology: beyond the sum of its parts. Nature Methods, 17 (1). pp. 17-20.

Ma, Manxiu and Ramirez, Alexandro D. and Wang, Tong and Roberts, Rachel L. and Harmon, Katherine E. and Schoppik, David and Sharma, Avirale and Kuang, Christopher and Goei, Stephanie L. and Gagnon, James A. and Zimmerman, Steve and Tsai, Shengdar Q. and Reyon, Deepak and Joung, J. Keith and Aksay, Emre R. F. and Schier, Alexander F. and Pan, Y. Albert. (2020) Zebrafish dscaml1 Deficiency Impairs Retinal Patterning and Oculomotor Function. Journal of Neuroscience, 40 (1). pp. 143-158.

2019

Haesemeyer, Martin and Schier, Alexander F. and Engert, Florian. (2019) Convergent Temperature Representations in Artificial and Biological Neural Networks. Neuron, 103 (6). pp. 1123-1134.e6.

Randlett, Owen and Haesemeyer, Martin and Forkin, Greg and Shoenhard, Hannah and Schier, Alexander F. and Engert, Florian and Granato, Michael. (2019) Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish. Current biology : CB, 29 (8). pp. 1337-1345.e4.

Goudarzi, Mehdi and Berg, Kathryn and Pieper, Lindsey M. and Schier, Alexander F.. (2019) Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility. eLife, 8. 8:e40815.

Thyme, Summer B. and Pieper, Lindsey M. and Li, Eric H. and Pandey, Shristi and Wang, Yiqun and Morris, Nathan S. and Sha, Carrie and Choi, Joo Won and Herrera, Kristian J. and Soucy, Edward R. and Zimmerman, Steve and Randlett, Owen and Greenwood, Joel and McCarroll, Steven A. and Schier, Alexander F.. (2019) Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Cell, 177 (2). pp. 478-491.e20.

Lord, Nathan D. and Carte, Adam N. and Abitua, Philip B. and Schier, Alexander F.. (2019) The pattern of nodal morphogen signaling is shaped by co-receptor expression.

Wee, Caroline L. and Nikitchenko, Maxim and Wang, Wei-Chun and Luks-Morgan, Sasha J. and Song, Erin and Gagnon, James A. and Randlett, Owen and Bianco, Isaac H. and Lacoste, Alix M. B. and Glushenkova, Elena and Barrios, Joshua P. and Schier, Alexander F. and Kunes, Samuel and Engert, Florian and Douglass, Adam D.. (2019) Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets. Nature neuroscience, 22 (9). pp. 1477-1492.

2018

Haesemeyer, Martin and Robson, Drew N. and Li, Jennifer M. and Schier, Alexander F. and Engert, Florian. (2018) A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish. Neuron, 98 (4). pp. 817-831.e6.

Pandey, Shristi and Shekhar, Karthik and Regev, Aviv and Schier, Alexander F.. (2018) Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq. Current biology : CB, 28 (7). pp. 1052-1065.e7.

Montague, Tessa G. and Gagnon, James A. and Schier, Alexander F.. (2018) Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse. Development (Cambridge, England), 145 (24). p. 9.

Raj, Bushra and Gagnon, James A. and Schier, Alexander F.. (2018) Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR-Cas9 barcodes by scGESTALT. Nature protocols, 13 (11). pp. 2685-2713.

Almuedo-Castillo, María and Bläßle, Alexander and Mörsdorf, David and Marcon, Luciano and Soh, Gary H. and Rogers, Katherine W. and Schier, Alexander F. and Müller, Patrick. (2018) Scale-invariant patterning by size-dependent inhibition of Nodal signalling. Nature cell biology, 20 (9). pp. 1032-1042.

Raj, Bushra and Wagner, Daniel E. and McKenna, Aaron and Pandey, Shristi and Klein, Allon M. and Shendure, Jay and Gagnon, James A. and Schier, Alexander F.. (2018) Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain. Nature biotechnology, 36 (5). pp. 442-450.

Farrell, Jeffrey A. and Wang, Yiqun and Riesenfeld, Samantha J. and Shekhar, Karthik and Regev, Aviv and Schier, Alexander F.. (2018) Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis. Science (New York, N.Y.), 360 (6392). p. 6.

Gagnon, James A. and Obbad, Kamal and Schier, Alexander F.. (2018) The primary role of zebrafish nanog is in extra-embryonic tissue. Development (Cambridge, England), 145 (1). p. 9.

2017

Rabani, Michal and Pieper, Lindsey and Chew, Guo-Liang and Schier, Alexander F.. (2017) A Massively Parallel Reporter Assay of 3' UTR Sequences Identifies In Vivo Rules for mRNA Degradation. Molecular Cell, 68 (6). pp. 1083-1094.e5.

Schoppik, David and Bianco, Isaac H. and Prober, David A. and Douglass, Adam D. and Robson, Drew N. and Li, Jennifer M. B. and Greenwood, Joel S. F. and Soucy, Edward and Engert, Florian and Schier, Alexander F.. (2017) Gaze-Stabilizing Central Vestibular Neurons Project Asymmetrically to Extraocular Motoneuron Pools. The Journal of Neuroscience, 37 (47). pp. 11353-11365.

Escamilla, Christine Ochoa and Filonova, Irina and Walker, Angela K. and Xuan, Zhong X. and Holehonnur, Roopashri and Espinosa, Felipe and Liu, Shunan and Thyme, Summer B. and López-García, Isabel A. and Mendoza, Dorian B. and Usui, Noriyoshi and Ellegood, Jacob and Eisch, Amelia J. and Konopka, Genevieve and Lerch, Jason P. and Schier, Alexander F. and Speed, Haley E. and Powell, Craig M.. (2017) Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature, 551 (7679). pp. 227-231.

Freyer, Laina and Hsu, Chih-Wei and Nowotschin, Sonja and Pauli, Andrea and Ishida, Junji and Kuba, Keiji and Fukamizu, Akiyoshi and Schier, Alexander F. and Hoodless, Pamela A. and Dickinson, Mary E. and Hadjantonakis, Anna-Katerina. (2017) Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell reports, 20 (9). pp. 2116-2130.

Rogers, Katherine W. and Lord, Nathan D. and Gagnon, James A. and Pauli, Andrea and Zimmerman, Steven and Aksel, Deniz C. and Reyon, Deepak and Tsai, Shengdar Q. and Joung, J. Keith and Schier, Alexander F.. (2017) Nodal patterning without Lefty inhibitory feedback is functional but fragile. eLife, 6. 6:e28785.

Norris, Megan L. and Pauli, Andrea and Gagnon, James A. and Lord, Nathan D. and Rogers, Katherine W. and Mosimann, Christian and Zon, Leonard I. and Schier, Alexander F.. (2017) Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. eLife, 6. 6:e22626.

Montague, Tessa G. and Schier, Alexander F.. (2017) Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm. eLife, 6. 6:e28183.

2016

Chiu, Cindy N. and Rihel, Jason and Lee, Daniel A. and Singh, Chanpreet and Mosser, Eric A. and Chen, Shijia and Sapin, Viveca and Pham, Uyen and Engle, Jae and Niles, Brett J. and Montz, Christin J. and Chakravarthy, Sridhara and Zimmerman, Steven and Salehi-Ashtiani, Kourosh and Vidal, Marc and Schier, Alexander F. and Prober, David A.. (2016) A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron, 89 (4). pp. 842-856.

Dunn, Timothy W. and Mu, Yu and Narayan, Sujatha and Randlett, Owen and Naumann, Eva A. and Yang, Chao-Tsung and Schier, Alexander F. and Freeman, Jeremy and Engert, Florian and Ahrens, Misha B.. (2016) Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion. eLife, 5. e12741.

Chew, Guo-Liang and Pauli, Andrea and Schier, Alexander F.. (2016) Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish. Nature communications, 7. p. 11663.

Li-Villarreal, Nanbing and Forbes, Meredyth M. and Loza, Andrew J. and Chen, Jiakun and Ma, Taylur and Helde, Kathryn and Moens, Cecilia B. and Shin, Jimann and Sawada, Atsushi and Hindes, Anna E. and Dubrulle, Julien and Schier, Alexander F. and Longmore, Gregory D. and Marlow, Florence L. and Solnica-Krezel, Lilianna. (2016) Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development, 143 (10). p. 1832.

Thyme, Summer B. and Akhmetova, Laila and Montague, Tessa G. and Valen, Eivind and Schier, Alexander F.. (2016) Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature communications, 7. p. 11750.

Thyme, Summer B. and Schier, Alexander F.. (2016) Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell reports, 15 (4). pp. 707-714.

McKenna, Aaron and Findlay, Gregory M. and Gagnon, James A. and Horwitz, Marshall S. and Schier, Alexander F. and Shendure, Jay. (2016) Whole-organism lineage tracing by combinatorial and cumulative genome editing. Science (New York, N.Y.), 353 (6298). aaf7907.

2015

Lacoste, Alix M. B. and Schoppik, David and Robson, Drew N. and Haesemeyer, Martin and Portugues, Ruben and Li, Jennifer M. and Randlett, Owen and Wee, Caroline L. and Engert, Florian and Schier, Alexander F.. (2015) A convergent and essential interneuron pathway for Mauthner-cell-mediated escapes. Current biology : CB, 25 (11). pp. 1526-1534.

Pauli, Andrea and Montague, Tessa G. and Lennox, Kim A. and Behlke, Mark A. and Schier, Alexander F.. (2015) Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PloS one, 10 (10). e0139504.

Li-Villarreal, Nanbing and Forbes, Meredyth M. and Loza, Andrew J. and Chen, Jiakun and Ma, Taylur and Helde, Kathryn and Moens, Cecilia B. and Shin, Jimann and Sawada, Atsushi and Hindes, Anna E. and Dubrulle, Julien and Schier, Alexander F. and Longmore, Gregory D. and Marlow, Florence L. and Solnica-Krezel, Lilianna. (2015) Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development, 142 (15). pp. 2704-2718.

Merkle, Florian T. and Neuhausser, Werner M. and Santos, David and Valen, Eivind and Gagnon, James A. and Maas, Kristi and Sandoe, Jackson and Schier, Alexander F. and Eggan, Kevin. (2015) Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus. Cell Reports , 11 (6). pp. 875-883.

Liu, Justin and Merkle, Florian T. and Gandhi, Avni V. and Gagnon, James A. and Woods, Ian G. and Chiu, Cindy N. and Shimogori, Tomomi and Schier, Alexander F. and Prober, David A.. (2015) Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development, 142 (6). pp. 1113-1124.

Merkle, Florian T. and Maroof, Asif and Wataya, Takafumi and Sasai, Yoshiki and Studer, Lorenz and Eggan, Kevin and Schier, Alexander F.. (2015) Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development (Cambridge, England), 142 (4). pp. 633-643.

Pauli, Andrea and Valen, Eivind and Schier, Alexander F.. (2015) Identifying (non-)coding RNAs and small peptides: challenges and opportunities. BioEssays : news and reviews in molecular, cellular and developmental biology, 37 (1). pp. 103-112.

Rogers, Katherine W. and Blässle, Alexander and Schier, Alexander F. and Müller, Patrick. (2015) Measuring protein stability in living zebrafish embryos using fluorescence decay after photoconversion (FDAP). Journal of visualized experiments (95). e52266.

Dubrulle, Julien and Jordan, Benjamin M. and Akhmetova, Laila and Farrell, Jeffrey A. and Kim, Seok-Hyung and Solnica-Krezel, Lilianna and Schier, Alexander F.. (2015) Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. eLife, 4. e05042.

Satija, Rahul and Farrell, Jeffrey A. and Gennert, David and Schier, Alexander F. and Regev, Aviv. (2015) Spatial reconstruction of single-cell gene expression data. Nature biotechnology, 33 (5). pp. 495-502.

Haesemeyer, Martin and Robson, Drew N. and Li, Jennifer M. and Schier, Alexander F. and Engert, Florian. (2015) The structure and timescales of heat perception in larval zebrafish. Cell Systems, 1 (5). pp. 338-348.

Haesemeyer, Martin and Schier, Alexander F.. (2015) The study of psychiatric disease genes and drugs in zebrafish. Current Opinion in Neurobiology, 30. pp. 122-130.

Mundell, Nathan A. and Beier, Kevin T. and Pan, Y. Albert and Lapan, Sylvain W. and Göz Aytürk, Didem and Berezovskii, Vladimir K. and Wark, Abigail R. and Drokhlyansky, Eugene and Bielecki, Jan and Born, Richard T. and Schier, Alexander F. and Cepko, Constance L.. (2015) Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms. Journal of Comparative Neurology, 523 (11). pp. 1639-1663.

Randlett, Owen and Wee, Caroline L. and Naumann, Eva A. and Nnaemeka, Onyeka and Schoppik, David and Fitzgerald, James E. and Portugues, Ruben and Lacoste, Alix M. B. and Riegler, Clemens and Engert, Florian and Schier, Alexander F.. (2015) Whole-brain activity mapping onto a zebrafish brain atlas. Nature Methods, 12 (11). pp. 1039-1046.

2014

Zhang, Yong and Vastenhouw, Nadine L. and Feng, Jianxing and Fu, Kai and Wang, Chenfei and Ge, Ying and Pauli, Andrea and van Hummelen, Paul and Schier, Alexander F. and Liu, X. Shirley. (2014) Canonical nucleosome organization at promoters forms during genome activation. Genome Research, 24 (2). pp. 260-266.

Gagnon, James A. and Valen, Eivind and Thyme, Summer B. and Huang, Peng and Akhmetova, Laila and Pauli, Andrea and Montague, Tessa G. and Zimmerman, Steven and Richter, Constance and Schier, Alexander F.. (2014) Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. PLoS ONE, 9 (5). e98186.

Rabani, Michal and Raychowdhury, Raktima and Jovanovic, Marko and Rooney, Michael and Stumpo, Deborah J. and Pauli, Andrea and Hacohen, Nir and Schier, Alexander F. and Blackshear, Perry J. and Friedman, Nir and Amit, Ido and Regev, Aviv. (2014) High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies. Cell, 159 (7). pp. 1698-1710.

Richter, Constance and Woods, Ian G. and Schier, Alexander F.. (2014) Neuropeptidergic control of sleep and wakefulness. Annual Review of Neuroscience, 37. pp. 503-531.

Woods, Ian G. and Schoppik, David and Shi, Veronica J. and Zimmerman, Steven and Coleman, Haley A. and Greenwood, Joel and Soucy, Edward R. and Schier, Alexander F.. (2014) Neuropeptidergic signaling partitions arousal behaviors in zebrafish. Journal of Neuroscience, 34 (9). pp. 3142-3160.

Schier, Alexander F.. (2014) Obituary: Walter J. Gehring (1939-2014). Development, 141 (17). pp. 3289-3291.

Pauli, Andrea and Norris, Megan L. and Valen, Eivind and Chew, Guo-Liang and Gagnon, James A. and Zimmerman, Steven and Mitchell, Andrew and Ma, Jiao and Dubrulle, Julien and Reyon, Deepak and Tsai, Shengdar Q. and Joung, J. Keith and Saghatelian, Alan and Schier, Alexander F.. (2014) Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science, 343 (6172). p. 1248636.

2013

Varshney, Gaurav K. and Lu, Jing and Gildea, Derek E. and Huang, Haigen and Pei, Wuhong and Yang, Zhongan and Huang, Sunny C. and Schoenfeld, David and Pho, Nam H. and Casero, David and Hirase, Takashi and Mosbrook-Davis, Deborah and Zhang, Suiyuan and Jao, Li-En and Zhang, Bo and Woods, Ian G. and Zimmerman, Steven and Schier, Alexander F. and Wolfsberg, Tyra G. and Pellegrini, Matteo and Burgess, Shawn M. and Lin, Shuo. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Research, 23 (4). pp. 727-735.

Schier, Alexander F.. (2013) Genomics: Zebrafish earns its stripes. Nature, 496 (7446). pp. 443-444.

Müller, Patrick and Rogers, Katherine W. and Yu, Shuizi R. and Brand, Michael and Schier, Alexander F.. (2013) Morphogen transport. Development (Cambridge, England), 140 (8). pp. 1621-1638.

Levitz, Joshua and Pantoja, Carlos and Gaub, Benjamin and Janovjak, Harald and Reiner, Andreas and Hoagland, Adam and Schoppik, David and Kane, Brian and Stawski, Philipp and Schier, Alexander F. and Trauner, Dirk and Isacoff, Ehud Y.. (2013) Optical control of metabotropic glutamate receptors. Nature neuroscience, 16 (4). pp. 507-516.

Chew, Guo-Liang and Pauli, Andrea and Rinn, John L. and Regev, Aviv and Schier, Alexander F. and Valen, Eivind. (2013) Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs. Development, 140 (13). pp. 2828-2834.

Schier, Alexander F.. (2013) Should I stay or should I go: neuromodulators of behavioral states. Cell, 154 (5). pp. 955-956.

Rihel, Jason and Schier, Alexander F.. (2013) Sites of action of sleep and wake drugs: insights from model organisms. Current Opinion in Neurobiology, 23 (5). pp. 831-840.

Xiong, Fengzhu and Tentner, Andrea R. and Huang, Peng and Gelas, Arnaud and Mosaliganti, Kishore R. and Souhait, Lydie and Rannou, Nicolas and Swinburne, Ian A. and Obholzer, Nikolaus D. and Cowgill, Paul D. and Schier, Alexander F. and Megason, Sean G.. (2013) Specified neural progenitors sort to form sharp domains after noisy Shh signaling. Cell, 153 (3). pp. 550-561.

Pan, Y. Albert and Freundlich, Tom and Weissman, Tamily A. and Schoppik, David and Wang, X. Cindy and Zimmerman, Steve and Ciruna, Brian and Sanes, Joshua R. and Lichtman, Jeff W. and Schier, Alexander F.. (2013) Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development, 140 (13). pp. 2835-2846.

2012

Huang, Peng and Xiong, Fengzhu and Megason, Sean G. and Schier, Alexander F.. (2012) Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord. PLoS Genetics, 8 (6). e1002762.

Pan, Y. Albert and Caron, Sophie J. C. and Schier, Alexander F.. (2012) BAPTI and BAPTISM birthdating of neurons in zebrafish. Cold Spring Harbor Protocols, 2012 (1). pp. 87-92.

Rihel, Jason and Schier, Alexander F.. (2012) Behavioral screening for neuroactive drugs in zebrafish. Developmental Neurobiology, 72 (3). pp. 373-385.

Vastenhouw, Nadine L. and Schier, Alexander F.. (2012) Bivalent histone modifications in early embryogenesis. Current Opinion in Cell Biology, 24 (3). pp. 374-386.

Ahrens, Misha B. and Li, Jennifer M. and Orger, Michael B. and Robson, Drew N. and Schier, Alexander F. and Engert, Florian and Portugues, Ruben. (2012) Brain-wide neuronal dynamics during motor adaptation in zebrafish. Nature, 485 (7399). pp. 471-477.

Panizzi, Jennifer R. and Becker-Heck, Anita and Castleman, Victoria H. and Al-Mutairi, Dalal A. and Liu, Yan and Loges, Niki T. and Pathak, Narendra and Austin-Tse, Christina and Sheridan, Eamonn and Schmidts, Miriam and Olbrich, Heike and Werner, Claudius and Häffner, Karsten and Hellman, Nathan and Chodhari, Rahul and Gupta, Amar and Kramer-Zucker, Albrecht and Olale, Felix and Burdine, Rebecca D. and Schier, Alexander F. and O'Callaghan, Christopher and Chung, Eddie M. K. and Reinhardt, Richard and Mitchison, Hannah M. and King, Stephen M. and Omran, Heymut and Drummond, Iain A.. (2012) CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nature Genetics, 44 (6). pp. 714-719.

Müller, Patrick and Rogers, Katherine W. and Jordan, Ben M. and Lee, Joon S. and Robson, Drew and Ramanathan, Sharad and Schier, Alexander F.. (2012) Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science, 336 (6082). pp. 721-724.

Xu, Cong and Fan, Zi Peng and Müller, Patrick and Fogley, Rachel and DiBiase, Anthony and Trompouki, Eirini and Unternaehrer, Juli and Xiong, Fengzhu and Torregroza, Ingrid and Evans, Todd and Megason, Sean G. and Daley, George Q. and Schier, Alexander F. and Young, Richard A. and Zon, Leonard I.. (2012) Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental Cell, 22 (3). pp. 625-638.

Pan, Y. Albert and Choy, Margaret and Prober, David A. and Schier, Alexander F.. (2012) Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons. Development, 139 (3). pp. 591-600.

Pauli, Andrea and Valen, Eivind and Lin, Michael F. and Garber, Manuel and Vastenhouw, Nadine L. and Levin, Joshua Z. and Fan, Lin and Sandelin, Albin and Rinn, John L. and Regev, Aviv and Schier, Alexander F.. (2012) Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis. Genome research, 22 (3). pp. 577-591.

Stooke-Vaughan, Georgina A. and Huang, Peng and Hammond, Katherine L. and Schier, Alexander F. and Whitfield, Tanya T.. (2012) The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development, 139 (10). pp. 1777-1787.

Bianco, Isaac H. and Ma, Leung-Hang and Schoppik, David and Robson, Drew N. and Orger, Michael B. and Beck, James C. and Li, Jennifer M. and Schier, Alexander F. and Engert, Florian and Baker, Robert. (2012) The tangential nucleus controls a gravito-inertial vestibulo-ocular reflex. Current Biology, 22 (14). pp. 1285-1295.

Low, Sean E. and Woods, Ian G. and Lachance, Mathieu and Ryan, Joel and Schier, Alexander F. and Saint-Amant, Louis. (2012) Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. Journal of Neurophysiology, 108 (1). pp. 148-159.

2011

Müller, Patrick and Schier, Alexander F.. (2011) Extracellular movement of signaling molecules. Developmental Cell, 21 (1). pp. 145-158.

Rogers, Katherine W. and Schier, Alexander F.. (2011) Morphogen gradients: from generation to interpretation. Annual Review of Cell and Developmental Biology, 27. pp. 377-407.

Pan, Y. Albert and Livet, Jean and Sanes, Joshua R. and Lichtman, Jeff W. and Schier, Alexander F.. (2011) Multicolor Brainbow imaging in zebrafish. Cold Spring Harbor Protocols, 2011 (1). db.prot5546.

Pauli, Andrea and Rinn, John L. and Schier, Alexander F.. (2011) Non-coding RNAs as regulators of embryogenesis. Nature reviews. Genetics, 12 (2). pp. 136-149.

2010

Vastenhouw, Nadine L. and Zhang, Yong and Woods, Ian G. and Imam, Farhad and Regev, Aviv and Liu, X. Shirley and Rinn, John and Schier, Alexander F.. (2010) Chromatin signature of embryonic pluripotency is established during genome activation. Nature, 464 (7290). pp. 922-926.

Naumann, Eva A. and Kampff, Adam R. and Prober, David A. and Schier, Alexander F. and Engert, Florian. (2010) Monitoring neural activity with bioluminescence during natural behavior. Nature Neuroscience, 13 (4). pp. 513-520.

Rihel, Jason and Prober, David A. and Schier, Alexander F.. (2010) Monitoring sleep and arousal in zebrafish. Methods in cell biology, 100. pp. 281-294.

Rihel, Jason and Prober, David A. and Arvanites, Anthony and Lam, Kelvin and Zimmerman, Steven and Jang, Sumin and Haggarty, Stephen J. and Kokel, David and Rubin, Lee L. and Peterson, Randall T. and Schier, Alexander F.. (2010) Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science, 327 (5963). pp. 348-351.

Harvey, Steven A. and Tümpel, Stefan and Dubrulle, Julien and Schier, Alexander F. and Smith, James C.. (2010) no tail integrates two modes of mesoderm induction. Development, 137 (7). pp. 1127-1135.

2009

Huang, Peng and Schier, Alexander F.. (2009) Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development, 136 (18). pp. 3089-3098.

Schier, Alexander F. and Needleman, Daniel. (2009) Developmental biology: Rise of the source-sink model. Nature, 461 (7263). pp. 480-481.

Schier, Alexander F.. (2009) Nodal morphogens. Cold Spring Harbor Perspectives in Biology, 1 (5). a003459.

2008

Knaut, Holger and Schier, Alexander F.. (2008) Clearing the path for germ cells. Cell, 132 (3). pp. 337-339.

Douglass, Adam D. and Kraves, Sebastian and Deisseroth, Karl and Schier, Alexander F. and Engert, Florian. (2008) Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Current Biology, 18 (15). pp. 1133-1137.

Caron, Sophie J. C. and Prober, David and Choy, Margaret and Schier, Alexander F.. (2008) In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development, 135 (19). pp. 3259-3269.

Choi, Philip S. and Zakhary, Lisa and Choi, Wen-Yee and Caron, Sophie and Alvarez-Saavedra, Ezequiel and Miska, Eric A. and McManus, Mike and Harfe, Brian and Giraldez, Antonio J. and Horvitz, H. Robert and Schier, Alexander F. and Dulac, Catherine. (2008) Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron, 57 (1). pp. 41-55.

de Campos-Baptista, Maria Ines Medeiros and Holtzman, Nathalia Glickman and Yelon, Deborah and Schier, Alexander F.. (2008) Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish. Developmental Dynamics, 237 (12). pp. 3624-3633.

Woods, Ian G. and Schier, Alexander F.. (2008) Targeted mutagenesis in zebrafish. Nature Biotechnology, 26 (6). pp. 650-651.

Prober, David A. and Zimmerman, Steven and Myers, Benjamin R. and McDermott, Brian M. and Kim, Seok-Hyung and Caron, Sophie and Rihel, Jason and Solnica-Krezel, Lilianna and Julius, David and Hudspeth, A. J. and Schier, Alexander F.. (2008) Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. Journal of Neuroscience, 28 (40). pp. 10102-10110.

2007

Bennett, James T. and Stickney, Heather L. and Choi, Wen-Yee and Ciruna, Brian and Talbot, William S. and Schier, Alexander F.. (2007) Maternal nodal and zebrafish embryogenesis. Nature, 450 (7167). E1-2; discussion E2-E4.

Bennett, James T. and Joubin, Katherine and Cheng, Simon and Aanstad, Pia and Herwig, Ralf and Clark, Matthew and Lehrach, Hans and Schier, Alexander F.. (2007) Nodal signaling activates differentiation genes during zebrafish gastrulation. Developmental Biology, 304 (2). pp. 525-540.

Choi, Wen-Yee and Giraldez, Antonio J. and Schier, Alexander F.. (2007) Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science, 318 (5848). pp. 271-274.

Schier, Alexander F.. (2007) The maternal-zygotic transition: death and birth of RNAs. Science, 316 (5823). pp. 406-407.

2006

Mishima, Yuichiro and Giraldez, Antonio J. and Takeda, Yasuaki and Fujiwara, Toshinobu and Sakamoto, Hiroshi and Schier, Alexander F. and Inoue, Kunio. (2006) Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430. Current Biology, 16 (21). pp. 2135-2142.

Prober, David A. and Rihel, Jason and Onah, Anthony A. and Sung, Rou-Jia and Schier, Alexander F.. (2006) Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. Journal of Neuroscience, 26 (51). pp. 13400-13410.

Ciruna, Brian and Jenny, Andreas and Lee, Diana and Mlodzik, Marek and Schier, Alexander F.. (2006) Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature, 439 (7073). pp. 220-224.

Obara, Tomoko and Mangos, Steven and Liu, Yan and Zhao, Jinhua and Wiessner, Stephanie and Kramer-Zucker, Albrecht G. and Olale, Felix and Schier, Alexander F. and Drummond, Iain A.. (2006) Polycystin-2 immunolocalization and function in zebrafish. Journal of the American Society of Nephrology, 17 (10). pp. 2706-2718.

Giraldez, Antonio J. and Mishima, Yuichiro and Rihel, Jason and Grocock, Russell J. and Van Dongen, Stijn and Inoue, Kunio and Enright, Anton J. and Schier, Alexander F.. (2006) Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science, 312 (5770). pp. 75-79.

2005

Knaut, Holger and Blader, Patrick and Strähle, Uwe and Schier, Alexander F.. (2005) Assembly of trigeminal sensory ganglia by chemokine signaling. Neuron, 47 (5). pp. 653-666.

Schier, Alexander F.. (2005) Axis formation: squint comes into focus. Current Biology, 15 (24). R1002-R1005.

Kramer-Zucker, Albrecht G. and Olale, Felix and Haycraft, Courtney J. and Yoder, Bradley K. and Schier, Alexander F. and Drummond, Iain A.. (2005) Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development, 132 (8). pp. 1907-1921.

Giraldez, Antonio J. and Cinalli, Ryan M. and Glasner, Margaret E. and Enright, Anton J. and Thomson, J. Michael and Baskerville, Scott and Hammond, Scott M. and Bartel, David P. and Schier, Alexander F.. (2005) MicroRNAs regulate brain morphogenesis in zebrafish. Science, 308 (5723). pp. 833-838.

Schier, Alexander F. and Talbot, William S.. (2005) Molecular genetics of axis formation in zebrafish. Annual Review of Genetics, 39. pp. 561-613.

Le Good, J. Ann and Joubin, Katherine and Giraldez, Antonio J. and Ben-Haim, Nadav and Beck, Séverine and Chen, Yu and Schier, Alexander F. and Constam, Daniel B.. (2005) Nodal stability determines signaling range. Current Biology, 15 (1). pp. 31-36.

Sagasti, Alvaro and Guido, Matthew R. and Raible, David W. and Schier, Alexander F.. (2005) Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors. Current Biology, 15 (9). pp. 804-814.

Tyurina, Oksana V. and Guner, Burcu and Popova, Evgenya and Feng, Jianchi and Schier, Alexander F. and Kohtz, Jhumku D. and Karlstrom, Rolf O.. (2005) Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Developmental Biology, 277 (2). pp. 537-556.

2004

Schier, Alexander F.. (2004) Developmental biology: tail of decay. Nature, 427 (6973). pp. 403-404.

Cheng, Simon K. and Olale, Felix and Brivanlou, Ali H. and Schier, Alexander F.. (2004) Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. PLoS biology, 2 (2). E30.

2003

Schier, Alexander F.. (2003) Chemokine signaling: rules of attraction. Current Biology, 13 (5). R192-R194.

Cheng, Simon K. and Olale, Felix and Bennett, James T. and Brivanlou, Ali H. and Schier, Alexander F.. (2003) EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes and Development, 17 (1). pp. 31-36.

Karlstrom, Rolf O. and Tyurina, Oksana V. and Kawakami, Atsushi and Nishioka, Noriyuki and Talbot, William S. and Sasaki, Hiroshi and Schier, Alexander F.. (2003) Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development, 130 (8). pp. 1549-1564.

Kunwar, Prabhat S. and Zimmerman, Steven and Bennett, James T. and Chen, Yu and Whitman, Malcolm and Schier, Alexander F.. (2003) Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development, 130 (23). pp. 5589-5599.

Schier, Alexander F.. (2003) Nodal signaling in vertebrate development. Annual review of cell and developmental biology, 19. pp. 589-621.

Dougan, Scott T. and Warga, Rachel M. and Kane, Donald A. and Schier, Alexander F. and Talbot, William S.. (2003) The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development, 130 (9). pp. 1837-1851.

2002

de la Cruz, June M. and Bamford, Richard N. and Burdine, Rebecca D. and Roessler, Erich and Barkovich, James A. and Donnai, Dian and Schier, Alexander F. and Muenke, Maximilian. (2002) A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects. Human genetics, 110 (5). pp. 422-428.

Moon, Ho-Sang and Jacobson, Eric M. and Khersonsky, Sonya M. and Luzung, Michael R. and Walsh, Daniel P. and Xiong, Wennan and Lee, Jae Wook and Parikh, Puja B. and Lam, Jennifer C. and Kang, Tae-Wook and Rosania, Gustavo R. and Schier, Alexander F. and Chang, Young-Tae. (2002) A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. Journal of the American Chemical Society, 124 (39). pp. 11608-11609.

Chen, Yu and Schier, Alexander F.. (2002) Lefty proteins are long-range inhibitors of squint-mediated nodal signaling. Current Biology, 12 (24). pp. 2124-2128.

Kimelman, David and Schier , Alexander F.. (2002) Mesoderm Induction and Patterning. In: Pattern Formation in Zebrafish. Heidelberg, pp. 15-27.

Ciruna, Brian and Weidinger, Gilbert and Knaut, Holger and Thisse, Bernard and Thisse, Christine and Raz, Erez and Schier, Alexander F.. (2002) Production of maternal-zygotic mutant zebrafish by germ-line replacement. Proceedings of the National Academy of Sciences of the United States of America, 99 (23). pp. 14919-14924.

Yamashita, Susumu and Miyagi, Chiemi and Carmany-Rampey, Amanda and Shimizu, Takashi and Fujii, Ritsuko and Schier, Alexander F. and Hirano, Toshio. (2002) Stat3 Controls Cell Movements during Zebrafish Gastrulation. Developmental Cell, 2 (3). pp. 363-375.

This list was generated on Thu Mar 28 10:43:53 2024 CET.