The study of psychiatric disease genes and drugs in zebrafish

Haesemeyer, Martin and Schier, Alexander F.. (2015) The study of psychiatric disease genes and drugs in zebrafish. Current Opinion in Neurobiology, 30. pp. 122-130.

Full text not available from this repository.

Official URL: https://edoc.unibas.ch/74134/

Downloads: Statistics Overview


Mutations associated with psychiatric disease are being identified, but it remains unclear how the affected genes contribute to disease. Zebrafish is an emerging model to study psychiatric disease genes with a rich repertoire of phenotyping tools. Recent zebrafish research has uncovered potential developmental phenotypes for genes associated with psychiatric disorders, while drug screens have behaviorally characterized small molecules and identified new classes of drugs. Behavioral studies have led to promising models for endophenotypes of psychiatric diseases. While further research is needed to firmly link these models to psychiatric disorders, they are valuable tools for phenotyping genetic mutations and drugs. Recently developed tools in genome editing and in vivo imaging promise additional insights into the processes disrupted by mutations in psychiatric disease genes.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Cell and Developmental Biology (Schier)
UniBasel Contributors:Schier, Alexander
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:26 May 2020 15:47
Deposited On:26 May 2020 15:47

Repository Staff Only: item control page