Knaut, Holger and Schier, Alexander F.. (2008) Clearing the path for germ cells. Cell, 132 (3). pp. 337-339.
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Official URL: https://edoc.unibas.ch/74734/
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Abstract
The chemokine SDF-1a and its receptor CXCR4b guide germ cell migration in zebrafish by activating downstream signaling events. Boldajipour et al. (2008) now report that a second SDF-1a receptor, CXCR7, is also required for guided migration but does not function as a signaling receptor, and instead sequesters SDF-1a. These results highlight the importance of ligand clearance during guided cell migration.
| Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Growth & Development > Cell and Developmental Biology (Schier) |
|---|---|
| UniBasel Contributors: | Schier, Alexander F |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Cell Press |
| ISSN: | 0092-8674 |
| e-ISSN: | 1097-4172 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 18 Dec 2020 14:35 |
| Deposited On: | 18 Dec 2020 14:35 |
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