Maternal nodal and zebrafish embryogenesis

Bennett, James T. and Stickney, Heather L. and Choi, Wen-Yee and Ciruna, Brian and Talbot, William S. and Schier, Alexander F.. (2007) Maternal nodal and zebrafish embryogenesis. Nature, 450 (7167). E1-2; discussion E2-E4.

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Official URL: https://edoc.unibas.ch/74859/

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In fish and amphibians, the dorsal axis is specified by the asymmetric localization of maternally provided components of the Wnt signalling pathway. Gore et al. suggest that the Nodal signal Squint (Sqt) is required as a maternally provided dorsal determinant in zebrafish. Here we test their proposal and show that the maternal activities of sqt and the related Nodal gene cyclops (cyc) are not required for dorsoventral patterning.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Cell and Developmental Biology (Schier)
UniBasel Contributors:Schier, Alexander F
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Nature Research
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:06 Nov 2020 13:47
Deposited On:06 Nov 2020 13:47

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