Browse by Basel Contributors ID

No

Keiser, J. and Speich, B. and Utzinger, J.. (2014) The authors reply : Yasukawa K. comment to "Oxantel pamoate-albendazole for Trichuris trichiura infection". The New England journal of medicine, Vol. 370, H. 20. p. 1953.

Jones, M. K. and Keiser, J. and McManus, D. P.. (2011) Trematodes. In: Manual of clinical microbiology, 2. Washington, pp. 2230-2242.

Keiser, Jennifer and Utzinger, Jürg. (2011) Foodborne trematodiasis and schistosomiasis. In: Rudolph's Pediatrics. New York, pp. 1200-1203.

Keiser, Jennifer. Pharmacological investigations on current and new drugs for treatment of human African trypanosomiasis. 1999, Doctoral Thesis, University of Basel, Faculty of Science.

Yes

Coulibaly, J. T. and Silue, K. D. and Armstrong, M. and Díaz de León Derby, M. and D'Ambrosio, M. V. and Fletcher, D. A. and Keiser, J. and Fisher, K. and Andrews, J. R. and Bogoch, I. I.. (2023) High sensitivity of mobile phone microscopy screening for Schistosoma haematobium in Azaguié, Côte d'Ivoire. The American journal of tropical medicine and hygiene, 108 (1). pp. 41-43.

Welsche, S. and Mrimi, E. C. and Hattendorf, J. and Hürlimann, E. and Ali, S. M. and Keiser, J.. (2023) Efficacy and safety of moxidectin and albendazole compared with ivermectin and albendazole coadministration in adolescents infected with Trichuris trichiura in Tanzania: an open-label, non-inferiority, randomised, controlled, phase 2/3 trial. The Lancet infectious diseases, 23 (3). pp. 331-340.

Biendl, S. and Häberli, C. and Chen, G. and Wang, W. and Zhong, L. and Saunders, J. and Pham, T. and Wang, X. and Wu, J. and Charman, S. A. and Vennerstrom, J. L. and Keiser, J.. (2023) In vitro; and; in vivo; antischistosomal activity profiling and pharmacokinetics of ozonide carboxylic acids. ACS Infect Dis, 9 (3). pp. 643-652.

Cappuccino, C. and Spoletti, E. and Renni, F. and Muntoni, E. and Keiser, J. and Voinovich, D. and Perissutti, B. and Lusi, M.. (2023) Co-crystalline solid solution affords a high-soluble and fast-absorbing form of praziquantel. Mol Pharm, 20 (4). pp. 2009-2016.

Hürlimann, E. and Hofmann, D. and Keiser, J.. (2023) Ivermectin and moxidectin against soil-transmitted helminth infections. Trends in parasitology, 39 (4). pp. 272-284.

Mrimi, E. C. and Palmeirim, M. S. and Minja, E. G. and Long, K. Z. and Keiser, J.. (2023) Correlation of cytokines with parasitic infections, undernutrition and micronutrient deficiency among schoolchildren in rural Tanzania: a cross-sectional study. Nutrients, 15 (8). p. 1916.

Coffeng, L. E. and Vlaminck, J. and Cools, P. and Denwood, M. and Albonico, M. and Ame, S. M. and Ayana, M. and Dana, D. and Cringoli, G. and de Vlas, S. J. and Fenwick, A. and French, M. and Kazienga, A. and Keiser, J. and Knopp, S. and Leta, G. and Matoso, L. F. and Maurelli, M. P. and Montresor, A. and Mirams, G. and Mekonnen, Z. and Corrêa-Oliveira, R. and Pinto, S. A. and Rinaldi, L. and Sayasone, S. and Steinmann, P. and Thomas, E. and Vercruysse, J. and Levecke, B.. (2023) A general framework to support cost-efficient fecal egg count methods and study design choices for large-scale STH deworming programs-monitoring of therapeutic drug efficacy as a case study. PLoS Negl Trop Dis, 17 (5). e0011071.

Easland, E. and Biendl, S. and Keiser, J.. (2023) Development of a hookworm egg hatching assay to determine the ovicidal effects of anthelminthics. Parasit Vectors, 16. p. 157.

Mrimi, E. C. and Welsche, S. and Ali, S. M. and Hattendorf, J. and Keiser, J.. (2023) Emodepside for Trichuris trichiura and hookworm infection. The New England journal of medicine, 388 (20). pp. 1863-1875.

Muya, K. and Kalonji, M. and Ilunga, N. W. and Maseho, M. and Kitambala, M. and Kalonda, M. and Ndoumba, K. and Byanga, K. and Wright, C. W. and Häberli, C. and Keiser, J. and Simbi, L.. (2023) Evaluation of 43 species of Congolese medicinal plants used traditionally for the treatment of schistosomiasis leading to the isolation of an anti-schistosomal phaeophytin from Pseudolachnostylis maprouneifolia Pax. J Ethnopharmacol, 315. p. 116688.

Specht, S. and Keiser, J.. (2023) Helminth infections: enabling the World Health Organization road map. Int J Parasitol, 53 (8). pp. 411-414.

D'Abbrunzo, I. and Bianco, E. and Gigli, L. and Demitri, N. and Birolo, R. and Chierotti, M. R. and Keiser, J. and Häberli, C. and Voinovich, D. and Hasa, D. and Perissutti, B.. (2023) Praziquantel meets Niclosamide: a dual-drug antiparasitic cocrystal. International journal of pharmaceutics, 644. p. 123315.

Friedrich, L. and Park, S. K. and Ballard, P. and Ho Baeurle, T. H. and Maillard, D. and Bödding, M. and Keiser, J. and Marchant, J. S. and Spangenberg, T.. (2023) Metabolism of (R)-Praziquantel versus the activation of a Parasite Transient Receptor Potential Melastatin ion channel. ChemMedChem, 18 (18). e202300140.

Kasago, F. M. and Häberli, C. and Keiser, J. and Masamba, W.. (2023) Design, synthesis and evaluation of praziquantel analogues and new molecular hybrids as potential antimalarial and anti-schistosomal agents. Molecules, 28 (13). p. 5184.

Angeli, A. and Ferraroni, M. and Carta, F. and Häberli, C. and Keiser, J. and Costantino, G. and Supuran, C. T.. (2022) Development of Praziquantel sulphonamide derivatives as antischistosomal drugs. J Enzyme Inhib Med Chem, 37 (1). pp. 1479-1494.

Biendl, S. and Häberli, C. and Keiser, J.. (2022) Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box. Expert Rev Anti Infect Ther, 20 (4). pp. 621-629.

Cantara, A. and Luo, Y. and Dobrovolna, M. and Bohalova, N. and Fojta, M. and Verga, D. and Guittat, L. and Cucchiarini, A. and Savrimoutou, S. and Häberli, C. and Guillon, J. and Keiser, J. and Brazda, V. and Mergny, J. L.. (2022) G-quadruplexes in helminth parasites. Nucleic Acids Res, 50 (5). pp. 2719-2735.

Coulibaly, J. T. and Hürlimann, E. and Patel, C. and Silué, D. K. and Avenié, D. J. and Kouamé, N. A. and Silué, U. M. and Keiser, J.. (2022) Optimizing implementation of preventive chemotherapy against soil-transmitted helminthiasis and intestinal schistosomiasis using high-resolution data: Field-based experiences from Côte d'Ivoire. Diseases, 10 (4). p. 66.

Di Bello, E. and Noce, B. and Fioravanti, R. and Zwergel, C. and Valente, S. and Rotili, D. and Fianco, G. and Trisciuoglio, D. and Mourão, M. M. and Sales, P. and Jr., and Lamotte, S. and Prina, E. and Späth, G. F. and Häberli, C. and Keiser, J. and Mai, A.. (2022) Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni. ACS Infect Dis, 8 (7). pp. 1356-1366.

Dube, M. and Llanes, D. and Saoud, M. and Rennert, R. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N.. (2022) Albatrellus confluens (Alb. & Schwein.) Kotl. & Pouz.: natural fungal compounds and synthetic derivatives with in vitro anthelmintic activities and antiproliferative effects against two human cancer cell lines. Molecules, 27 (9). p. 2950.

Dube, M. and Raphane, B. and Sethebe, B. and Seputhe, N. and Tiroyakgosi, T. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N. and Andrae-Marobela, K.. (2022) Medicinal plant preparations administered by botswana traditional health practitioners for treatment of worm infections show anthelmintic activities. Plants (Basel), 11 (21). p. 2945.

Falcoz, C. and Guzy, S. and Kovač, J. and Meister, I. and Coulibaly, J. and Sayasone, S. and Wesche, D. and Lin, Y. W. and Keiser, J.. (2022) R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with; Schistosoma mansoni; and; S. haematobium; and Lao adults infected with; Opisthorchis viverrini. J Pharmacokinet Pharmacodyn, 49 (3). pp. 293-310.

Grolimund, C. and Bärenbold, O. and Utzinger, J. and Keiser, J. and Vounatsou, P.. (2022) Modeling the effect of different drugs and treatment regimen for hookworm on cure and egg reduction rates taking into account diagnostic error. PLoS Negl Trop Dis, 16 (10). e0010810.

Harrington, S. and Knox, J. J. and Burns, A. R. and Choo, K. L. and Au, A. and Kitner, M. and Haeberli, C. and Pyche, J. and D'Amata, C. and Kim, Y. H. and Volpatti, J. R. and Guiliani, M. and Snider, J. and Wong, V. and Palmeira, B. M. and Redman, E. M. and Vaidya, A. S. and Gilleard, J. S. and Stagljar, I. and Cutler, S. R. and Kulke, D. and Dowling, J. J. and Yip, C. M. and Keiser, J. and Zasada, I. and Lautens, M. and Roy, P. J.. (2022) Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release. Commun Biol, 5. p. 865.

Hassan, M. M. and Sedighi, A. and Olaoye, O. O. and Haberli, C. and Merz, A. and Ramos-Morales, E. and de Araujo, E. D. and Romier, C. and Jung, M. and Keiser, J. and Gunning, P. T.. (2022) Phenotypic screening of histone deacetylase (HDAC) inhibitors against Schistosoma mansoni. ChemMedChem. e202100622.

Herath, H. M. P. D. and Taki, A. C. and Rostami, A. and Jabbar, A. and Keiser, J. and Geary, T. G. and Gasser, R. B.. (2022) Whole-organism phenotypic screening methods used in early-phase anthelmintic drug discovery. Biotechnol Adv, 57. p. 107937.

Hofmann, D. and Brussee, J. M. and Schulz, J. D. and Coulibaly, J. T. and Pfister, M. and Keiser, J.. (2022) Pharmacokinetic modelling and simulation to optimize albendazole dosing in hookworm- or Trichuris trichiura-infected infants to adults. J Antimicrob Chemother, 77 (4). pp. 1082-1093.

Hofmann, D. and Smit, C. and Sayasone, S. and Pfister, M. and Keiser, J.. (2022) Optimizing moxidectin dosing for Strongyloides stercoralis infections: insights from pharmacometric modeling. Clin Transl Sci, 15 (3). pp. 700-708.

Hürlimann, E. and Keller, L. and Patel, C. and Welsche, S. and Hattendorf, J. and Ali, S. M. and Ame, S. M. and Sayasone, S. and Coulibaly, J. T. and Keiser, J.. (2022) Efficacy and safety of co-administered ivermectin and albendazole in school-aged children and adults infected with; Trichuris trichiura; in Côte d'Ivoire, Laos, and Pemba Island, Tanzania: a double-blind, parallel-group, phase 3, randomised controlled trial. The Lancet infectious diseases, 22 (1). pp. 123-135.

Kersting, L. and Kuhn, L. and Anokhin, M. and Schuster, F. and Häberli, C. and Sambyal, S. and Kumar, H. M. S. and Keiser, J. and Alabugin, I. and Tsogoeva, S. B.. (2022) Visible-light-driven metal-free C-H functionalization: access to new bioactive tetrahydroisoquinoline-butenolide hybrids via domino amine oxidation/vinylogous mannich reaction. ChemPhotoChem, 6 (8). e202200109.

Mrimi, E. C. and Palmeirim, M. S. and Minja, E. G. and Long, K. Z. and Keiser, J.. (2022) Malnutrition, anemia, micronutrient deficiency and parasitic infections among schoolchildren in rural Tanzania. PLoS Negl Trop Dis, 16 (3). e0010261.

Olliaro, P. L. and Vaillant, M. T. and Diawara, A. and Speich, B. and Albonico, M. and Utzinger, J. and Keiser, J.. (2022) Egg excretion indicators for the measurement of soil-transmitted helminth response to treatment. PLoS Negl Trop Dis, 16 (8). e0010593.

Probst, A. and Biendl, S. and Keiser, J.. (2022) Improving translational power in antischistosomal drug discovery. Advances in parasitology, 117. pp. 47-73.

Probst, A. and Hofmann, D. and Fedorova, O. S. and Mazeina, S. V. and Sokolova, T. S. and Golovach, E. and Keiser, J.. (2022) Pharmacokinetics of ascending doses of praziquantel in adults infected with Opisthorchis felineus in Western Siberia, Russian Federation. Antimicrobial agents and chemotherapy, 66 (10). e00526-22.

Qian, M. B. and Patel, C. and Palmeirim, M. S. and Wang, X. and Schindler, C. and Utzinger, J. and Zhou, X. N. and Keiser, J.. (2022) Efficacy of drugs against clonorchiasis and opisthorchiasis: a systematic review and network meta-analysis. Lancet Microbe, 3 (8). e616-e624.

Ravaynia, P. S. and Biendl, S. and Grassi, F. and Keiser, J. and Hierlemann, A. and Modena, M. M.. (2022) Real-time and automated monitoring of antischistosomal drug activity profiles for screening of compound libraries. iScience, 25 (4). p. 104087.

Ren, R. and Wang, X. and Leas, D. A. and Häberli, C. and Cal, M. and Dong, Y. and Kaiser, M. and Keiser, J. and Vennerstrom, J. L.. (2022) Antischistosomal tetrahydro-γ-carboline sulfonamides. Bioorganic & medicinal chemistry letters, 59. p. 128546.

Schneeberger, P. H. H. and Gueuning, M. and Welsche, S. and Hürlimann, E. and Dommann, J. and Haberli, C. and Frey, J. E. and Sayasone, S. and Keiser, J.. (2022) Different gut microbial communities correlate with efficacy of albendazole-ivermectin against soil-transmitted helminthiases. Nat Commun, 13. p. 1063.

Smit, C. and Hofmann, D. and Sayasone, S. and Keiser, J. and Pfister, M.. (2022) Characterization of the population pharmacokinetics of moxidectin in adults infected with strongyloides stercoralis: support for a fixed-dose treatment regimen. Clinical pharmacokinetics, 61. pp. 123-132.

Taki, A. C. and Wang, T. and Nguyen, N. N. and Ang, C. S. and Leeming, M. G. and Nie, S. and Byrne, J. J. and Young, N. D. and Zheng, Y. and Ma, G. and Korhonen, P. K. and Koehler, A. V. and Williamson, N. A. and Hofmann, A. and Chang, B. C. H. and Haberli, C. and Keiser, J. and Jabbar, A. and Sleebs, B. E. and Gasser, R. B.. (2022) Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868. Front Pharmacol, 13. p. 1014804.

Taljaard, L. and Probst, A. and Tornow, R. and Keiser, J. and Haynes, R. K. and van der Kooy, F.. (2022) In vitro antischistosomal activity of Artemisia annua and Artemisia afra extracts. Phytomed Plus, 2 (3). p. 100279.

Noce, B. and Di Bello, E. and Zwergel, C. and Fioravanti, R. and Valente, S. and Rotili, D. and Masotti, A. and Ansari, M. S. Z. and Trisciuoglio, D. and Chakrabarti, A. and Romier, C. and Robaa, D. and Sippl, W. and Jung, M. and Häberli, C. and Keiser, J. and Mai, A.. (2022) Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages. ChemMedChem. In press.

Valderas-García, E. and Häberli, C. and Álvarez-Bardón, M. and Escala, N. and Castilla-Gómez de Agüero, V. and de la Vega, J. and Del Olmo, E. and Balaña-Fouce, R. and Keiser, J. and Martínez-Valladares, M.. (2022) Benzimidazole and aminoalcohol derivatives show in vitro anthelmintic activity against Trichuris muris and Heligmosomoides polygyrus. Parasit Vectors, 15. p. 243.

Walker, M. and Freitas, L. T. and Halder, J. B. and Brack, M. and Keiser, J. and King, C. H. and Levecke, B. and Ai-Lian Lim, Y. and Pieri, O. and Sow, D. and Stothard, J. R. and Webster, J. P. and Zhou, X. N. and Terry, R. F. and Guérin, P. J. and Basáñez, M. G.. (2022) Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data. Wellcome Open Res, 7. p. 5.

Falcoz, C. and Guzy, S. and Kovac, J. and Meister, I. and Coulibaly, J. and Sayasone, S. and WEsche, D. and Lin, Y. W. and Keiser, J.. (2022) Correction to: R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini. J Pharmacokinet Pharmacodyn, 49 (3). p. 395.

Hamway, Y. and Zimmermann, K. and Blommers, M. J. J. and Sousa, M. and Häberli, C. and Kulkarni, S. and Skalicky, S. and Hackl, M. and Götte, M. and Keiser, J. and da Costa, C. P. and Spangenberg, T. and Azzaoui, K.. (2022) Modulation of host-parasite interactions with small molecules targeting Schistosoma mansoni microRNAs. ACS Infect Dis, 8. 2028−2034.

Bosch, Felix and Palmeirim, Marta S. and Ali, Said M. and Ame, Shaali M. and Hattendorf, Jan and Keiser, Jennifer. (2021) Diagnosis of soil-transmitted helminths using the Kato-Katz technique: what is the influence of stirring, storage time and storage temperature on stool sample egg counts? PLoS neglected tropical diseases, 15. e0009032.

Brussee, Janneke M. and Hiroshige, Noemi and Neodo, Anna and Coulibaly, Jean T. and Pfister, Marc and Keiser, Jennifer. (2021) Population pharmacokinetics and exposure-response analysis of tribendimidine to improve treatment for children with hookworm infection. Antimicrobial agents and chemotherapy, 65 (2). e01778-20.

Brussee, Janneke M. and Neodo, Anna and Schulz, Jessica D. and Coulibaly, Jean T. and Pfister, Marc and Keiser, Jennifer. (2021) Pharmacometric analysis of tribendimidine mono- and combination therapies to achieve high cure rates in patients with hookworm infections. Antimicrobial agents and chemotherapy, 65 (2). e00714-20.

Buchter, V. and Schneeberger, P. H. H. and Keiser, J.. (2021) Validation of a human-serum-based in vitro growth method for drug screening on juvenile development stages of Schistosoma mansoni. PLoS Negl Trop Dis, 15 (3). e0009313.

Buchter, V. and Hofmann, D. and Häberli, C. and Keiser, J.. (2021) Characterization of moxidectin against; Strongyloides ratti:; in vitro; and; in vivo; activity and pharmacokinetics in the rat model. ACS Infect Dis, 7 (5). pp. 1069-1076.

Dube, M. and Saoud, M. and Rennert, R. and Fotso, G. W. and Andrae-Marobela, K. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N.. (2021) Anthelmintic activity and cytotoxic effects of compounds isolated from the fruits of Ozoroa insignis del. (Anacardiaceae). Biomolecules, 11 (12). p. 1893.

Debbert, S. L. and Hintz, M. J. and Bell, C. J. and Earl, K. R. and Forsythe, G. E. and Häberli, C. and Keiser, J.. (2021) Activities of quinoxaline, nitroquinoxaline and [1,2,4]triazolo[4,3-a]quinoxaline analogs of MMV007204 against; Schistosoma mansoni. Antimicrobial agents and chemotherapy, 65 (3). e01370-20.

Keller, L. and Welsche, S. and Patel, C. and Sayasone, S. and Ali, S. M. and Ame, S. M. and Hattendorf, J. and Hürlimann, E. and Keiser, J.. (2021) Long-term outcomes of ivermectin-albendazole versus albendazole alone against soil-transmitted helminths: results from randomized controlled trials in Lao PDR and Pemba Island, Tanzania. PLoS Negl Trop Dis, 15 (6). e0009561.

Keller, L. and Hürlimann, E. and Patel, C. and Welsche, S. and Sayasone, S. and Ali, S. M. and Ame, S. M. and Coulibaly, J. T. and Keiser, J.. (2021) Insights gained from conductinga randomised controlled trial onIvermectin-albendazole against Trichuris trichiura in Côte d'Ivoire, Lao PDR and Pemba Island. Advances in parasitology, 111. pp. 253-276.

Keiser, J. and Häberli, C.. (2021) Assessment of FDA-approved drugs against Strongyloides ratti in vitro and in vivo to identify potentially active drugs against strongyloidiasis. Parasit Vectors, 14. p. 615.

Keiser, J. and Häberli, C.. (2021) Evaluation of commercially available anthelminthics in laboratory models of human intestinal nematode infections. ACS Infect Dis, 7 (5). pp. 1177-1185.

Jittamala, P. and Monteiro, W. and Smit, M. R. and Pedrique, B. and Specht, S. and Chaccour, C. J. and Dard, C. and Del Giudice, P. and Khieu, V. and Maruani, A. and Failoc-Rojas, V. E. and Saez-de-Ocariz, M. and Soriano-Arandes, A. and Piquero-Casals, J. and Faisant, A. and Brenier-Pinchart, M. P. and Wimmersberger, D. and Coulibaly, J. T. and Keiser, J. and Boralevi, F. and Sokana, O. and Marks, M. and Engelman, D. and Romani, L. and Steer, A. C. and von Seidlein, L. and White, N. J. and Harriss, E. and Stepniewska, K. and Humphreys, G. S. and Kennon, K. and Guerin, P. J. and Kobylinski, K. C.. (2021) A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: is it time to reconsider the current contraindication? PLoS Negl Trop Dis, 15 (3). e0009144.

Hofmann, D. and Sayasone, S. and Sengngam, K. and Chongvilay, B. and Hattendorf, J. and Keiser, J.. (2021) Efficacy and safety of ascending doses of moxidectin against; Strongyloides stercoralis; infections in adults: a randomised, parallel-group, single-blinded, placebo-controlled, dose-ranging, phase 2a trial. Lancet Infect Dis, 21 (8). pp. 1151-1160.

Hofmann, D. and Sayasone, S. and Keiser, J.. (2021) Development and validation of an LC-MS/MS method for the quantification of the anthelmintic drug moxidectin in a volumetric absorptive microsample, blood, and plasma: application to a pharmacokinetic study of adults infected with Strongyloides stercoralis in Laos. J Chromatogr B Analyt Technol Biomed Life Sci, 1166. p. 122556.

Lombardo, F. C. and Ravaynia, P. S. and Modena, M. M. and Hierlemann, A. and Keiser, J.. (2021) Evaluation of human liver microtissues for drug screening on Schistosoma mansoni schistosomula. ACS Infect Dis, 7 (7). pp. 1894-1900.

Krücken, J. and Holden-Dye, L. and Keiser, J. and Prichard, R. K. and Townson, S. and Makepeace, B. L. and Hubner, M. P. and Hahnel, S. R. and Scandale, I. and Harder, A. and Kulke, D.. (2021) Development of emodepside as a possible adulticidal treatment for human onchocerciasis-the fruit of a successful industrial-academic collaboration. PLoS Pathog, 17 (7). e1009682.

Probst, A. and Pujol, E. and Häberli, C. and Keiser, J. and Vázquez, S.. (2021) In vitro, in vivo, and ADME evaluation of SF5-containing N,N'-diarylureas as antischistosomal agents. Antimicrobial agents and chemotherapy, 65 (10). e0061521.

Probst, A. and Chisanga, K. and Dziwornu, G. A. and Häberli, C. and Keiser, J. and Chibale, K.. (2021) Expanding the activity profile of pyrido[1,2-a]benzimidazoles: synthesis and evaluation of novel n(1)-1-phenylethanamine derivatives against Schistosoma mansoni. ACS Infect Dis, 7 (5). pp. 1032-1043.

Patel, C. and Keller, L. and Welsche, S. and Hattendorf, J. and Sayasone, S. and Ali, S. M. and Ame, S. M. and Coulibaly, J. T. and Hürlimann, E. and Keiser, J.. (2021) Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a case-control substudy conducted in Côte d'Ivoire, Lao PDR and Pemba Island, Tanzania. EClinicalMedicine, 32. p. 100724.

Patel, C. and Coulibaly, J. T. and Hofmann, D. and N'Gbesso, Y. and Hattendorf, J. and Keiser, J.. (2021) Efficacy and safety of albendazole in hookworm-infected preschool-aged children, school-aged children and adults in Côte d'Ivoire: a phase II randomized controlled dose-finding trial. Clinical infectious diseases, 73 (2). e494-e502.

Partridge, F. A. and Bataille, C. J. R. and Forman, R. and Marriott, A. E. and Forde-Thomas, J. and Häberli, C. and Dinsdale, R. L. and O'Sullivan, J. D. B. and Willis, N. J. and Wynne, G. M. and Whiteland, H. and Archer, J. and Steven, A. and Keiser, J. and Turner, J. D. and Hoffmann, K. F. and Taylor, M. J. and Else, K. J. and Russell, A. J. and Sattelle, D. B.. (2021) Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni. ACS Infect Dis, 7 (5). pp. 1260-1274.

Palmeirim, M. S. and Specht, S. and Scandale, I. and Gander-Meisterernst, I. and Chabicovsky, M. and Keiser, J.. (2021) Preclinical and clinical characteristics of the trichuricidal drug oxantel pamoate and clinical development plans: a review. Drugs, 81 (8). pp. 907-921.

Palmeirim, M. S. and Mrimi, E. C. and Minja, E. G. and Samson, A. J. and Keiser, J.. (2021) A cross-sectional survey on parasitic infections in schoolchildren in a rural Tanzanian community. Acta Trop, 213. p. 105737.

Palmeirim, M. S. and Mohammed, U. A. and Ross, A. and Ame, S. M. and Ali, S. M. and Keiser, J.. (2021) Evaluation of two communication tools, slideshow and theater, to improve participants' understanding of a clinical trial in the informed consent procedure on Pemba Island, Tanzania. PLoS Negl Trop Dis, 15 (5). e0009409.

Nguyen, W. and Lee, E. F. and Evangelista, M. and Lee, M. and Harris, T. J. and Colman, P. M. and Smith, N. A. and Williams, L. B. and Jarman, K. E. and Lowes, K. N. and Häberli, C. and Keiser, J. and Smith, B. J. and Fairlie, W. D. and Sleebs, B. E.. (2021) Optimization of benzothiazole and thiazole hydrazones as inhibitors of schistosome bcl-2a. ACS Infect Dis, 7 (5). pp. 1143-1163.

Sirak, B. and Asres, K. and Hailu, A. and Dube, M. and Arnold, N. and Häberli, C. and Keiser, J. and Imming, P.. (2021) In vitro antileishmanial and antischistosomal activities of anemonin isolated from the fresh leaves of Ranunculus multifidus forsk. Molecules, 26 (24). p. 7473.

Sy, I. and Margardt, L. and Ngbede, E. O. and Adah, M. I. and Yusuf, S. T. and Keiser, J. and Rehner, J. and Utzinger, J. and Poppert, S. and Becker, S. L.. (2021) Identification of adult Fasciola spp. using matrix-assisted laser/desorption ionization time-of-flight (MALDI-TOF) mass spectrometry. Microorganisms, 9. p. 82.

Welsche, S. and Mrimi, E. C. and Keller, L. and Hürlimann, E. and Hofmann, D. and Hattendorf, J. and Ali, S. M. and Keiser, J.. (2021) Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with Trichuris trichiura: a randomized controlled trial protocol. Gates Open Res, 5. p. 106.

Walker, M. and Cools, P. and Albonico, M. and Ame, S. M. and Ayana, M. and Dana, D. and Keiser, J. and Matoso, L. F. and Montresor, A. and Mekonnen, Z. and Corrêa-Oliveira, R. and Pinto, S. A. and Sayasone, S. and Vercruysse, J. and Vlaminck, J. and Levecke, B.. (2021) Individual responses to a single oral dose of albendazole indicate reduced efficacy against soil-transmitted helminths in an area with high drug pressure. PLoS Negl Trop Dis, 15 (10). e0009888.

Wagner-Hattler , Leonie and Québatte, Gabriela and Keiser, Jennifer and Schoelkopf, Joachim and Schleputz, Christian M. and Huwyler, Jörg and Puchkov, Maxim. (2020) Study of drug particle distributions within mini-tablets using synchrotron X-ray microtomography and superpixel image clustering. International Journal of Pharmaceutics, 573. p. 118827.

Palmeirim, M. S. and Ross, A. and Obrist, B. and Mohammed, U. A. and Ame, S. M. and Ali, S. M. and Keiser, J.. (2020) Informed consent procedure in a double blind randomized anthelminthic trial on Pemba Island, Tanzania: do pamphlet and information session increase caregivers knowledge? BMC medical ethics, 21. p. 1.

De Rycker, Manu and Horn, David and Aldridge, Bree and Amewu, Richard K. and Barry, Clifton E. and Buckner, Frederick S. and Cook, Sarah and Ferguson, Michael A. J. and Gobeau, Nathalie and Herrmann, Jennifer and Herrling, Paul and Hope, William and Keiser, Jennifer and Lafuente-Monasterio, Maria Jose and Leeson, Paul D. and Leroy, Didier and Manjunatha, Ujjini H. and McCarthy, James and Miles, Timothy J. and Mizrahi, Valerie and Moshynets, Olena and Niles, Jacquin and Overington, John P. and Pottage, John and Rao, Srinivasa P. S. and Read, Kevin D. and Ribeiro, Isabela and Silver, Lynn L. and Southern, Jen and Spangenberg, Thomas and Sundar, Shyam and Taylor, Caitlin and Van Voorhis, Wes and White, Nicholas J. and Wyllie, Susan and Wyatt, Paul G. and Gilbert, Ian H.. (2020) Setting our sights on infectious diseases. ACS infectious diseases, 6 (1). pp. 3-13.

Keller, Ladina and Palmeirim, Marta S. and Ame, Shaali M. and Ali, Said M. and Puchkov, Maxim and Huwyler, Jörg and Hattendorf, Jan and Keiser, Jennifer. (2020) Efficacy and safety of ascending dosages of moxidectin and moxidectin-albendazole against Trichuris trichiura in adolescents: a randomized controlled trial. Clinical Infectious Diseases, 70 (6). pp. 1193-1201.

Zanolla, Debora and Hasa, Dritan and Arhangelskis, Mihails and Schneider-Rauber, Gabriela and Chierotti, Michele R. and Keiser, Jennifer and Voinovich, Dario and Jones, William and Perissutti, Beatrice. (2020) Mechanochemical formation of racemic praziquantel hemihydrate with improved biopharmaceutical properties. Biopharmaceutics & drug disposition, 12 (3). p. 289.

Vlaminck, Johnny and Cools, Piet and Albonico, Marco and Ame, Shaali and Chanthapaseuth, Thipphavanh and Viengxay, Vanisaveth and Do Trung, Dung and Osei-Atweneboana, Mike Y. and Asuming-Brempong, Elias and Jahirul Karim, Mohammad and Al Kawsar, Abdullah and Keiser, Jennifer and Khieu, Virak and Faye, Babacar and Turate, Innocent and Mbonigaba, Jean Bosco and Ruijeni, Nadine and Shema, Eliah and Luciañez, Ana and Santiago Nicholls, Ruben and Jamsheed, Mohamed and Mikhailova, Alexei and Montresor, Antonio and Mupfasoni, Denise and Yajima, Aya and Ngina Mwinzi, Pauline and Gilleard, John and Prichard, Roger K. and Verweij, Jaco J. and Vercruysse, Jozef and Levecke, Bruno. (2020) Piloting a surveillance system to monitor the global patterns of drug efficacy and the emergence of anthelmintic resistance in soil-transmitted helminth control programs: a Starworms study protocol. Gates open research, 4. p. 28.

Moser, Wendelin and Keiser, Jennifer and Speich, Benjamin and Sayasone, Somphou and Knopp, Stefanie and Hattendorf, Jan. (2020) One mean to rule them all? The arithmetic mean based egg reduction rate can be misleading when estimating anthelminthic drug efficacy in clinical trials. PLoS Neglected Tropical Diseases, 14 (4). e0008185.

Wu, Jianbo and Wang, Xiaofang and Chiu, Francis C. K. and Häberli, Cécile and Shackleford, David M. and Ryan, Eileen and Kamaraj, Sriraghavan and Bulbule, Vivek J. and Wallick, Alexander I. and Dong, Yuxiang and White, Karen L. and Davis, Paul H. and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2020) Structure-activity relationship of antischistosomal ozonide carboxylic acids. Journal of medicinal chemistry, 63 (7). pp. 3723-3736.

Else, Kathryn J. and Keiser, Jennifer and Holland, Celia V. and Grencis, Richard K. and Sattelle, David B. and Fujiwara, Ricardo T. and Bueno, Lilian L. and Asaolu, Samuel O. and Sowemimo, Oluyomi A. and Cooper, Philip J.. (2020) Whipworm and roundworm infections. Nature Reviews. Disease Primers, 6 (1). p. 44.

Buchter, Valentin and Priotti, Josefina and Leonardi, Darío and Lamas, María C. and Keiser, Jennifer. (2020) Preparation, physicochemical characterization and In vitro and In vivo activity against Heligmosomoides polygyrus of novel oral formulations of albendazole and mebendazole. Journal of Pharmaceutical Sciences, 109 (5). pp. 1819-1826.

Patel, Chandni and Coulibaly, Jean T. and Schulz, Jessica D. and N'Gbesso, Yves and Hattendorf, Jan and Keiser, Jennifer. (2020) Efficacy and safety of ascending dosages of albendazole against Trichuris trichiura in preschool-aged children, school-aged children and adults: a multi-cohort randomized controlled trial. EClinicalMedicine, 22. p. 100335.

Lin, Yan and Ong, Yih Ching and Keller, Sarah and Karges, Johannes and Bouchene, Rafika and Manoury, Eric and Blacque, Olivier and Müller, Joachim and Anghel, Nicoleta and Hemphill, Andrew and Häberli, Cécile and Taki, Aya C. and Gasser, Robin B. and Cariou, Kevin and Keiser, Jennifer and Gasser, Gilles. (2020) Synthesis, characterization and antiparasitic activity of organometallic derivatives of the anthelmintic drug albendazole. Dalton Transactions, 49 (20). pp. 6616-6626.

Olliaro, Piero L. and Coulibaly, Jean T. and Garba, Amadou and Halleux, Christine and Keiser, Jennifer and King, Charles H. and Mutapi, Francisca and N'Goran, Eliézer K. and Raso, Giovanna and Scherrer, Alexandra U. and Sousa-Figueiredo, José Carlos and Stete, Katarina and Utzinger, Jürg and Vaillant, Michel T.. (2020) Efficacy and safety of single 40 mg/kg oral praziquantel in the treatment of schistosomiasis in preschool-age versus school-age children: an individual participant data meta-analysis. PLoS Neglected Tropical Diseases, 14 (6). e0008277.

Probst, Alexandra and Häberli, Cécile and Siegel, Dionicio and Huang, Jianbo and Vigneron, Seth and Ta, Anh P. and Skinner, Danielle E. and El-Sakkary, Nelly and Momper, Jeremiah D. and Gangoiti, Jon and Dong, Yuxiang and Vennerstrom, Jonathan L. and Charman, Susan A. and Caffrey, Conor R. and Keiser, Jennifer. (2020) Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone. The journal of antimicrobial chemotherapy. dkaa247.

Levecke, Bruno and Cools, Piet and Albonico, Marco and Ame, Shaali and Angebault, Cécile and Ayana, Mio and Behnke, Jerzy M. and Bethony, Jeffrey M. and Cringoli, Giuseppe and Dana, Daniel and Guillard, Bertrand and Viet Hoa, Nguyen Thi and Kang, Gagandeep and Kattula, Deepthi and Keiser, Jennifer and Kotze, Andrew C. and Matoso, Leonardo F. and Maurelli, Maria P. and McCarthy, James S. and Mekonnen, Zeleke and Mirams, Greg and Montresor, Antonio and Oliveira, Rodrigo Corrêa and Periago, Maria V. and Pinto, Simone A. and Rinaldi, Laura and Sayasone, Somphou and Sumo, Laurentine and Tchuem-Tchuenté, Louis-Albert and Cam Thach, Dang Thi and Thomas, Eurion and Zeynudin, Ahmed and Verweij, Jaco J. and Vlaminck, Johnny and Vercruysse, Jozef. (2020) Identifying thresholds to classify moderate-to-heavy soil-transmitted helminth intensity infections for FECPAKG2, McMaster, Mini-FLOTAC and qPCR. PLoS Neglected Tropical Diseases, 14 (7). e0008296.

Keiser, Jennifer and Koch, Vanessa and Deckers, Anke and Cheung, H. T. Andrew and Jung, Nicole and Bräse, Stefan. (2020) Naturally occurring cardenolides affecting Schistosoma mansoni. ACS infectious diseases, 6 (7). pp. 1922-1927.

Ravaynia, Paolo S. and Lombardo, Flavio C. and Biendl, Stefan and Dupuch, Matthias A. and Keiser, Jennifer and Hierlemann, Andreas and Modena, Mario M.. (2020) Parallelized impedance-based platform for continuous dose-response characterization of antischistosomal drugs. Advanced biosystems, 4 (7). e1900304.

Vlaminck, Johnny and Cools, Piet and Albonico, Marco and Ame, Shaali and Ayana, Mio and Dana, Daniel and Keiser, Jennifer and Matoso, Leonardo F. and Montresor, Antonio and Mekonnen, Zeleke and Corrêa-Oliveira, Rodrigo and Pinto, Simone A. and Sayasone, Somphou and Vercruysse, Jozef and Levecke, Bruno. (2020) An in-depth report of quality control on Kato-Katz and data entry in four clinical trials evaluating the efficacy of albendazole against soil-transmitted helminth infections. PLoS neglected tropical diseases, 14 (9). e0008625.

Barda, Beatrice and Schindler, Christian and Wampfler, Rahel and Ame, Shaali and Ali, Said M. and Keiser, Jennifer. (2020) Comparison of real-time PCR and the Kato-Katz method for the diagnosis of soil-transmitted helminthiasis and assessment of cure in a randomized controlled trial. BMC microbiology, 20. p. 298.

Buchter, Valentin and Ong, Yih Ching and Mouvet, François and Ladaycia, Abdallah and Lepeltier, Elise and Rothlisberger, Ursula and Keiser, Jennifer and Gasser, Gilles. (2020) Multidisciplinary preclinical investigations on three oxamniquine analogues as novel drug candidates for schistosomiasis. Chemistry (Weinheim an der Bergstrasse, Germany), 26 (66). pp. 15232-15241.

Keller, L. and Patel, C. and Welsche, S. and Schindler, T. and Hürlimann, E. and Keiser, J.. (2020) Performance of the Kato-Katz method and real time polymerase chain reaction for the diagnosis of soil-transmitted helminthiasis in the framework of a randomised controlled trial: treatment efficacy and day-to-day variation. Parasit Vectors, 13. p. 517.

Palmeirim, M. S. and Bosch, F. and Ame, S. M. and Ali, S. M. and Hattendorf, J. and Keiser, J.. (2020) Efficacy, safety and acceptability of a new chewable formulationversusthe solid tablet of mebendazole against hookworm infections in children: an open-label, randomized controlled trial. EClinicalMedicine, 27. p. 100556.

Twumasi, E. B. and Akazue, P. I. and Kyeremeh, K. and Gwira, T. M. and Keiser, J. and Cho-Ngwa, F. and Flint, A. and Anibea, B. and Bonsu, E. Y. and Amewu, R. K. and Amoah, L. E. and Appiah-Opong, R. and Osei-Safo, D.. (2020) Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents. PLoS Negl Trop Dis, 14 (12). e0008919.

Neodo, Anna and Schulz, Jessica D. and Huwyler, Jörg and Keiser, Jennifer. (2019) In vitro and In vivo drug-drug interaction study of the effects of ivermectin and oxantel pamoate on tribendimidine. Antimicrobial agents and chemotherapy, 63 (1). e00762-18.

Lombardo, Flavio C. and Pasche, Valérian and Panic, Gordana and Endriss, Yvette and Keiser, Jennifer. (2019) Life cycle maintenance and drug-sensitivity assays for early drug discovery in Schistosoma mansoni. Nature Protocols, 14 (2). pp. 461-481.

Le, Thuy and Kundu, Abhijit and Ghoshal, Atanu and Nguyen, Nghi and Preston, Sarah and Jiao, Yaqing and Ruan, Banfeng and Xue, Lian and Huang, Fei and Keiser, Jennifer and Hofmann, Andreas and Chang, Bill and Garcia-Bustos, Jose and Wells, Timothy N. C. and Palmer, Michael J. and Jabbar, Abdul and Gasser, Robin B. and Baell, Jonathan B.. (2019) Structure-activity relationship studies of tolfenpyrad reveal sub-nanomolar inhibitors of Haemonchus contortus development. Journal of medicinal chemistry, 62 (2). pp. 1036-1053.

Mayoka, Godfrey and Keiser, Jennifer and Häberli, Cécile and Chibale, Kelly. (2019) Structure-activity relationship and in vitro absorption, distribution, metabolism, excretion, and toxicity (ADMET) studies of N-aryl 3-trifluoromethyl pyrido[1,2-a]benzimidazoles that are efficacious in a mouse model of Schistosomiasis. ACS infectious diseases, 5 (3). pp. 418-429.

Moser, Wendelin and Schindler, Christian and Keiser, Jennifer. (2019) Drug combinations against soil-transmitted helminth infections. Advances in Parasitology, 103. pp. 91-115.

Albertini, Beatrice and Perissutti, Beatrice and Bertoni, Serena and Zanolla, Debora and Franceschinis, Erica and Voinovich, Dario and Lombardo, Flavio and Keiser, Jennifer and Passerini, Nadia. (2019) Combining mechanochemistry and spray congealing for new praziquantel pediatric formulations in schistosomiasis treatment. International journal of molecular sciences, 20 (5). p. 1233.

Patel, Chandni and Hürlimann, Eveline and Keller, Ladina and Hattendorf, Jan and Sayasone, Somphou and Ali, Said M. and Ame, Shaali M. and Coulibaly, Jean T. and Keiser, Jennifer. (2019) Efficacy and safety of ivermectin and albendazole co-administration in school-aged children and adults infected with Trichuris trichiura : study protocol for a multi-country randomized controlled double-blind trial. BMC infectious diseases, 19. p. 262.

Le, Thuy G. and Kundu, Abhijit and Ghoshal, Atanu and Nguyen, Nghi H. and Preston, Sarah and Jiao, Yaqing and Ruan, Banfeng and Xue, Lian and Huang, Fei and Keiser, Jennifer and Hofmann, Andreas and Chang, Bill C. H. and Garcia-Bustos, Jose and Wells, Timothy N. C. and Palmer, Michael J. and Jabbar, Abdul and Gasser, Robin B. and Baell, Jonathan B.. (2019) Novel 1-methyl-1 H-pyrazole-5-carboxamide derivatives with potent anthelmintic activity. Journal of medicinal chemistry, 62 (7). pp. 3367-3380.

Schulz, Jessica D. and Neodo, Anna and Coulibaly, Jean T. and Keiser, Jennifer. (2019) Pharmacokinetics of albendazole, albendazole sulfoxide and albendazole sulfone determined from plasma, blood, dried blood spots and Mitra® samples of hookworm-infected adolescents. Antimicrobial agents and chemotherapy, 63 (4). e02489-18.

Meister, Isabel and Assawasuwannakit, Piyanan and Vanobberghen, Fiona and Penny, Melissa A. and Odermatt, Peter and Sayasone, Somphou and Huwyler, Jörg and Tarning, Joel and Keiser, Jennifer. (2019) Pooled population pharmacokinetic analysis of tribendimidine for the treatment of Opisthorchis viverrini infections. Antimicrobial Agents and Chemotherapy, 63 (4). e01391-18.

Karpstein, Tanja and Pasche, Valérian and Häberli, Cécile and Scandale, Ivan and Neodo, Anna and Keiser, Jennifer. (2019) Evaluation of emodepside in laboratory models of human intestinal nematode and schistosome infections. Parasites and Vectors, 12. p. 226.

Schulz, Jessica D. and Coulibaly, Jean T. and Schindler, Christian and Wimmersberger, David and Keiser, Jennifer. (2019) Pharmacokinetics of ascending doses of ivermectin in Trichuris trichiura-infected children aged 2-12 years. The journal of antimicrobial chemotherapy, 74 (6). pp. 1642-1647.

Keiser, J. and Utzinger, J.. (2019) Community-wide soil-transmitted helminth treatment is equity-effective. Lancet, 393 (10185). pp. 2011-2012.

Panic, Gordana and Barda, Beatrice and Kovač, Jana and Coulibaly, Jean T. and Keiser, Jennifer. (2019) Evaluation of the Clinitek®, a point-of-care urinalysis system for the measurement of clinically significant urinary metabolites and detection of haematuria in Schistosoma haematobium infected children in southern Côte d'Ivoire. Parasites and vectors, 12. p. 298.

Bogoch, Isaac I. and Speich, Benjamin and Lo, Nathan C. and Moser, Wendelin and Croll, David and Ali, Said M. and Ame, Shaali M. and Utzinger, Jürg and Andrews, Jason R. and Keiser, Jennifer. (2019) Clinical evaluation for morbidity associated with soil-transmitted helminth infection in school-age children on Pemba Island, Tanzania. PLoS Neglected Tropical Diseases, 13 (7). e0007581.

Cools, Piet and Vlaminck, Johnny and Albonico, Marco and Ame, Shaali and Ayana, Mio and José Antonio, Barrios Perez and Cringoli, Giuseppe and Dana, Daniel and Keiser, Jennifer and Maurelli, Maria P. and Maya, Catalina and Matoso, Leonardo F. and Montresor, Antonio and Mekonnen, Zeleke and Mirams, Greg and Corrêa-Oliveira, Rodrigo and Pinto, Simone A. and Rinaldi, Laura and Sayasone, Somphou and Thomas, Eurion and Verweij, Jaco J. and Vercruysse, Jozef and Levecke, Bruno. (2019) Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted helminths in three endemic countries. PLoS Neglected Tropical Diseases, 13 (8). e0007446.

Vlaminck, Johnny and Cools, Piet and Albonico, Marco and Ame, Shaali and Ayana, Mio and Cringoli, Giuseppe and Dana, Daniel and Keiser, Jennifer and Maurelli, Maria P. and Matoso, Leonardo F. and Montresor, Antonio and Mekonnen, Zeleke and Mirams, Greg and Corrêa-Oliveira, Rodrigo and Pinto, Simone A. and Rinaldi, Laura and Sayasone, Somphou and Thomas, Eurion and Vercruysse, Jozef and Verweij, Jaco J. and Levecke, Bruno. (2019) Therapeutic efficacy of albendazole against soil-transmitted helminthiasis in children measured by five diagnostic methods. PLoS Neglected Tropical Diseases, 13 (8). e0007471.

Brussee, Janneke M. and Schulz, Jessica D. and Coulibaly, Jean T. and Keiser, Jennifer and Pfister, Marc. (2019) Ivermectin dosing strategy to achieve equivalent exposure coverage in children and adults. Clinical pharmacology and therapeutics, 106 (3). pp. 661-667.

Coulibaly, Jean T. and Hiroshige, Noemi and N'Gbesso, Yves K. and Hattendorf, Jan and Keiser, Jennifer. (2019) Efficacy and safety of ascending dosages of tribendimidine against hookworm infections in children : a randomized controlled trial. Clinical Infectious Diseases, 69 (5). pp. 845-852.

Lombardo, Flavio C. and Perissutti, Beatrice and Keiser, Jennifer. (2019) Activity and pharmacokinetics of a praziquantel crystalline polymorph in the Schistosoma mansoni mouse model. European Journal of Pharmaceutics and Biopharmaceutics, 142. pp. 240-246.

Wimmersberger, D. and Schulz, J. D. and Keiser, J.. (2019) Antihelminthic efficacy against trichuriasis reply. Clinical infectious diseases, 69 (2). pp. 376-377.

Brecht, Karin and Kirchhofer, Carla and Bouitbir, Jamal and Trapani, Francesca and Keiser, Jennifer and Krähenbühl, Stephan. (2019) Exogenous iron increases fasciocidal activity and hepatocellular toxicity of the synthetic endoperoxides OZ78 and MT04. International Journal of Molecular Sciences, 20 (19). p. 4880.

Wimmersberger, D. and Schulz, J. D. and Keiser, J.. (2019) Reply to Nalin. Clinical infectious diseases, 69 (2). pp. 376-377.

Hürlimann, E. and Keiser, J.. (2019) A single dose of ivermectin is sufficient for strongyloidiasis. The Lancet infectious diseases, 19 (11). pp. 1150-1151.

Maccesi, Martina and Aguiar, Pedro H. N. and Pasche, Valérian and Padilla, Melody and Suzuki, Brian M. and Montefusco, Sandro and Abagyan, Ruben and Keiser, Jennifer and Mourão, Marina M. and Caffrey, Conor R.. (2019) Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery. Parasites and Vectors, 12 (1). p. 493.

Zanolla, Debora and Perissutti, Beatrice and Vioglio, Paolo Cerreia and Chierotti, Michele R. and Gigli, Lara and Demitri, Nicola and Passerini, Nadia and Albertini, Beatrice and Franceschinis, Erica and Keiser, Jennifer and Voinovich, Dario. (2019) Exploring mechanochemical parameters using a DoE approach: Crystal structure solution from synchrotron XRPD and characterization of a new praziquantel polymorph. European Journal of Pharmaceutical Sciences, 140. p. 105084.

Kyne, G. M. and Curtis, M. P. and Keiser, J. and Woods, D. J.. (2019) Soil-transmitted helminthiasis - challenges with discovery of novel anthelmintics. In: Neglected tropical diseases: drug discovery and development. Weinheim, pp. 227-251.

Levecke, Bruno and Easton, Alice V. and Cools, Piet and Albonico, Marco and Ame, Shaali and Gilleard, John S. and Keiser, Jennifer and Montresor, Antonio and Prichard, Roger and Vlaminck, Johnny and Vercruysse, Jozef. (2018) The optimal timing of post-treatment sampling for the assessment of anthelminthic drug efficacy against Ascaris infections in humans. International Journal for Parasitology: Drugs and Drug Resistance, 8 (1). pp. 67-69.

Sayasone, Somphou and Keiser, Jennifer and Meister, Isabel and Vonghachack, Youthanavanh and Xayavong, Syda and Senggnam, Kanpaseuth and Phongluxa, Khampheng and Hattendorf, Jan and Odermatt, Peter. (2018) Efficacy and safety of tribendimidine versus praziquantel against Opisthorchis viverrini in Laos : an open-label, randomised, non-inferiority, phase 2 trial. The Lancet infectious diseases, 18 (2). pp. 155-161.

Schneeberger, Pierre H. H. and Coulibaly, Jean T. and Panic, Gordana and Daubenberger, Claudia and Gueuning, Morgan and Frey, Jürg E. and Keiser, Jennifer. (2018) Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome. Parasites and Vectors, 11. p. 168.

Speich, Benjamin and von Niederhäusern, Belinda and Blum, Claudine Angela and Keiser, Jennifer and Schur, Nadine and Fürst, Thomas and Kasenda, Benjamin and Christ-Crain, Mirjam and Hemkens, Lars G. and Pauli-Magnus, Christiane and Schwenkglenks, Matthias and Briel, Matthias and Making Randomized Trials Affordable Group, . (2018) Retrospective assessment of resource use and costs in two investigator-initiated randomized trials exemplified a comprehensive cost item list. Journal of clinical epidemiology, 96. pp. 73-83.

Barda, Beatrice and Ame, Shaali M. and Ali, Said M. and Albonico, Marco and Puchkov, Maxim and Huwyler, Jörg and Hattendorf, Jan and Keiser, Jennifer. (2018) Efficacy and tolerability of moxidectin alone and in co-administration with albendazole and tribendimidine versus albendazole plus oxantel pamoate against Trichuris trichiura infections : a randomised, non-inferiority, single-blind trial. The Lancet infectious diseases, 18 (8). pp. 864-873.

Barda, Beatrice and Wampfler, Rahel and Sayasone, Somphou and Phongluxa, Khampheng and Xayavong, Syda and Keoduangsy, Khonsavanh and Schindler, Christian and Keiser, Jennifer. (2018) Evaluation of two DNA extraction methods for detection of Strongyloides stercoralis infection. Journal of clinical microbiology, 56 (4). e01941-17.

Coulibaly, Jean T. and Panic, Gordana and Yapi, Richard B. and Kovač, Jana and Barda, Beatrice and N'Gbesso, Yves K. and Hattendorf, Jan and Keiser, Jennifer. (2018) Efficacy and safety of ascending doses of praziquantel against Schistosoma haematobium infection in preschool-aged and school-aged children : a single-blind randomised controlled trial. BMC Medicine, 16. p. 81.

Zanolla, Debora and Perissutti, Beatrice and Passerini, Nadia and Chierotti, Michele R. and Hasa, Dritan and Voinovich, Dario and Gigli, Lara and Demitri, Nicola and Geremia, Silvano and Keiser, Jennifer and Cerreia Vioglio, Paolo and Albertini, Beatrice. (2018) A new soluble and bioactive polymorph of praziquantel. European Journal of Pharmaceutics and Biopharmaceutics, 127. pp. 19-28.

Panic, Gordana and Coulibaly, Jean T. and Harvey, Nikita and Keiser, Jennifer and Swann, Jonathan. (2018) Characterizing the biochemical response to Schistosoma mansoni infection and treatment with praziquantel in preschool and school aged children. Journal of Proteome Research, 17 (6). pp. 2028-2033.

Moser, Wendelin and Sayasone, Somphou and Xayavong, Syda and Bounheuang, Bangon and Puchkov, Maxim and Huwyler, Jörg and Hattendorf, Jan and Keiser, Jennifer. (2018) Efficacy and tolerability of triple drug therapy with albendazole, pyrantel pamoate, and oxantel pamoate compared with albendazole plus oxantel pamoate, pyrantel pamoate plus oxantel pamoate, and mebendazole plus pyrantel pamoate and oxantel pamoate against hookworm infections in school-aged children in Laos : a randomised, single-blind trial. The Lancet infectious diseases, 18 (7). pp. 729-737.

Schulz, Jessica D. and Moser, Wendelin and Hürlimann, Eveline and Keiser, Jennifer. (2018) Preventive chemotherapy in the fight against soil-transmitted Helminthiasis : achievements and limitations. Trends in parasitology, 34 (7). pp. 590-602.

Schulz, J. D. and Neodo, A. and Coulibaly, J. T. and Keiser, J.. (2018) Development and validation of a LC-MS/MS method for ivermectin quantification in dried blood spots : application to a pharmacokinetic study in Trichuris trichiura-infected adults. Analytical Methods, 10. pp. 2901-2909.

Schneeberger, Pierre H. H. and Coulibaly, Jean T. and Gueuning, Morgan and Moser, Wendelin and Coburn, Bryan and Frey, Jürg E. and Keiser, Jennifer. (2018) Off-target effects of tribendimidine, tribendimidine plus ivermectin, tribendimidine plus oxantel-pamoate, and albendazole plus oxantel-pamoate on the human gut microbiota. International journal for parasitology. Drugs and drug resistance, 8 (3). pp. 372-378.

Kovač, Jana and Panic, Gordana and Neodo, Anna and Meister, Isabel and Coulibaly, Jean T. and Schulz, Jessica D. and Keiser, Jennifer. (2018) Evaluation of a novel micro-sampling device, Mitratm, in comparison to dried blood spots, for analysis of praziquantel in Schistosoma haematobium-infected children in rural Côte d'Ivoire. Journal of Pharmaceutical and Biomedical Analysis, 151. pp. 339-346.

Kovač, Jana and Meister, Isabel and Neodo, Anna and Panic, Gordana and Coulibaly, Jean T. and Falcoz, Christine and Keiser, Jennifer. (2018) Pharmacokinetics of praziquantel in Schistosoma mansoni and Schistosoma haematobium infected school- and preschool- aged children. Antimicrobial agents and chemotherapy, 62 (8). e02253-17.

Panic, Gordana and Keiser, Jennifer. (2018) Acting beyond 2020 : better characterization of praziquantel and promising antischistosomal leads. Current Opinion in Pharmacology, 42. pp. 27-33.

Becker, Sören L. and Liwanag, Harvy Joy and Snyder, Jedidiah S. and Akogun, Oladele and Belizario, Vicente and Freeman, Matthew C. and Gyorkos, Theresa W. and Imtiaz, Rubina and Keiser, Jennifer and Krolewiecki, Alejandro and Levecke, Bruno and Mwandawiro, Charles and Pullan, Rachel L. and Addiss, David G. and Utzinger, Jürg. (2018) Toward the 2020 goal of soil-transmitted helminthiasis control and elimination. PLoS Neglected Tropical Diseases, 12 (8). e0006606.

Wimmersberger, David and Coulibaly, Jean T. and Schulz, Jessica D. and Puchkow, Maxim and Huwyler, Jörg and N'Gbesso, Yves and Hattendorf, Jan and Keiser, Jennifer. (2018) Efficacy and safety of ivermectin against Trichuris trichiura in preschool- and school-aged children : a randomized controlled dose-finding trial. Clinical Infectious Diseases, 67 (8). pp. 1247-1255.

Hiroshige, Noemi and Coulibaly, Jean and Huwyler, Jörg and Bonate, Peter L. and Keiser, Jennifer. (2018) Pharmacokinetics of a Pediatric Tribendimidine Dose-Finding Study To Treat Hookworm Infection in African Children. Antimicrobial agents and chemotherapy, 62 (9). e00959.

Coulibaly, Jean T. and Ouattara, Mamadou and Barda, Beatrice and Utzinger, Jürg and N'Goran, Eliézer K. and Keiser, Jennifer. (2018) A rapid appraisal of factors influencing praziquantel treatment compliance in two communities endemic for schistosomiasis in Côte d'Ivoire. Tropical medicine and infectious disease, 3 (2). p. 69.

Ayana, Mio and Vlaminck, Johnny and Cools, Piet and Ame, Shaali and Albonico, Marco and Dana, Daniel and Keiser, Jennifer and Manly, Helen and Matoso, Leonardo F. and Mekonnen, Zeleke and Montresor, Antonio and Correa-Oliveira, Rodrigo and Rinaldi, Laura and Sayasone, Somphou and Tesfaye, Lensa and Vercruysse, Jozef and Mirams, Greg and Levecke, Bruno. (2018) Modification and optimization of the FECPAKG2 protocol for the detection and quantification of soil-transmitted helminth eggs in human stool. PLoS Neglected Tropical Diseases, 12 (10). e0006655.

Liu, Zhigang and Xia, Bing and Saric, Jasmina and Utzinger, Jürg and Holmes, Elaine and Keiser, Jennifer and Li, Jia V.. (2018) Effects of vancomycin and ciprofloxacin on the NMRI mouse metabolism. Journal of Proteome Research, 17 (10). pp. 3565-3573.

Vlaminck, Johnny and Cools, Piet and Albonico, Marco and Ame, Shaali and Ayana, Mio and Bethony, Jeffrey and Cringoli, Giuseppe and Dana, Daniel and Keiser, Jennifer and Maurelli, Maria P. and Montresor, Antonio and Mekonnen, Zeleke and Mirams, Greg and Corrêa-Oliveira, Rodrigo and Prichard, Roger and Rashwan, Nour and Rinaldi, Laura and Sayasone, Somphou and Thomas, Eurion and Verweij, Jaco J. and Vercruysse, Jozef and Levecke, Bruno. (2018) Comprehensive evaluation of stool-based diagnostic methods and benzimidazole resistance markers to assess drug efficacy and detect the emergence of anthelmintic resistance : a Starworms study protocol. PLoS Neglected Tropical Diseases, 12 (11). e0006912.

Buchter, Valentin and Hess, Jeannine and Gasser, Gilles and Keiser, Jennifer. (2018) Assessment of tegumental damage to Schistosoma mansoni and S. haematobium after in vitro exposure to ferrocenyl, ruthenocenyl and benzyl derivatives of oxamniquine using scanning electron microscopy. Parasites and Vectors, 11. p. 580.

D'Orchymont, F. Hess and J. Panic, G. Jakubaszek and M. Gemperle, L. Keiser and J. Gasser, G.. (2018) Synthesis, characterization and biological activity of organometallic derivatives of the antimalarial drug mefloquine as new antischistosomal drug candidate. MedChemComm , 9 (44). pp. 1905-1909.

Wu, Jianbo and Wang, Chunkai and Häberli, Cécile and White, Karen L. and Shackleford, David M. and Chen, Gong and Dong, Yuxiang and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2018) SAR of a new antischistosomal urea carboxylic acid. Bioorganic & medicinal chemistry letters, 28 (23-24). pp. 3648-3651.

Bonate, Peter L. and Wang, Tianli and Passier, Paul and Bagchus, Wilhelmina and Burt, Howard and Lüpfert, Christian and Abla, Nada and Kovac, Jana and Keiser, Jennifer. (2018) Extrapolation of praziquantel pharmacokinetics to a pediatric population : a cautionary tale. Journal of pharmacokinetics and pharmacodynamics, 45 (5). pp. 747-762.

Wu, Jianbo and Wang, Chunkai and Leas, Derek and Vargas, Mireille and White, Karen L. and Shackleford, David M. and Chen, Gong and Sanford, Austin G. and Hemsley, Ryan M. and Davis, Paul H. and Dong, Yuxiang and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2018) Progress in antischistosomal N,N'-diaryl urea SAR. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, 28 (3). pp. 244-248.

Le, Thuy G. and Kundu, Abhijit and Ghoshal, Atanu and Nguyen, Nghi H. and Preston, Sarah and Jiao, Yaqing and Ruan, Banfeng and Xue, Lian and Huang, Fei and Keiser, Jennifer and Hofmann, Andreas and Chang, Bill C. H. and Garcia-Bustos, Jose and Jabbar, Abdul and Wells, Timothy N. C. and Palmer, Michael J. and Gasser, Robin B. and Baell, Jonathan B.. (2018) Optimization of novel 1-methyl-1 h-pyrazole-5-carboxamides leads to high potency larval development inhibitors of the barber's pole worm. Journal of medicinal chemistry, 61 (23). pp. 10875-10894.

Chawla, Ketki and Modena, Mario M. and Ravaynia, Paolo S. and Lombardo, Flavio C. and Leonhardt, Martin and Panic, Gordana and Bürgel, Sebastian C. and Keiser, Jennifer and Hierlemann, Andreas. (2018) Impedance-based microfluidic assay for automated antischistosomal drug screening. ACS Sensors, 3 (12). pp. 2613-2620.

Palmeirim, M. S. and Ame, S. M. and Ali, S. M. and Hattendorf, J. and Keiser, J.. (2018) Efficacy and safety of a single dose versus a multiple dose regimen of mebendazole against hookworm infections in children : a randomised, double-blind trial. EClinicalMedicine, 1. pp. 7-13.

Pasche, Valérian and Laleu, Benoît and Keiser, Jennifer. (2018) Early antischistosomal leads identified from in vitro and in vivo screening of the medicines for malaria venture pathogen box. ACS infectious diseases, 5 (1). pp. 102-110.

Pasche, V. and Laleu, B. and Keiser, J.. (2018) Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni. Parasites and Vectors, 11. p. 298.

Moser, W. and Barenbold, O. and Mirams, G. J. and Cools, P. and Vlaminck, J. and Ali, S. M. and Ame, S. M. and Hattendorf, J. and Vounatsou, P. and Levecke, B. and Keiser, J.. (2018) Diagnostic comparison between FECPAKG2 and the Kato-Katz method for analyzing soil-transmitted helminth eggs in stool. PLoS neglected tropical diseases, 12 (6). e0006562.

Coulibaly, Jean T. and Andrews, Jason R. and Lo, Nathan C. and N'Goran, Eliézer K. and Utzinger, Jürg and Keiser, Jennifer and Bogoch, Isaac I.. (2018) Schistosoma haematobium egg excretion does not increase after exercise : implications for diagnostic testing. American journal of tropical medicine and hygiene, 98 (3). pp. 772-775.

Barda, Beatrice and Coulibaly, Jean T. and Hatz, Christoph and Keiser, Jennifer. (2017) Ultrasonographic evaluation of urinary tract morbidity in school-aged and preschool-aged children infected with Schistosoma haematobium and its evolution after praziquantel treatment : a randomized controlled trial. PLoS Neglected Tropical Diseases, 11 (2). e0005400.

Keiser, J.. (2017) Jennifer Keiser - tackling drug resistance before it arises. Trends in parasitology, 33 (3). pp. 153-154.

Moser, Wendelin and Labhardt, Niklaus Daniel and Cheleboi, Molisana and Muhairwe, Josephine and Keiser, Jennifer. (2017) Unexpected low soil-transmitted helminth prevalence in the Butha-Buthe district in Lesotho, results from a cross-sectional survey. Parasites and Vectors, 10. p. 72.

Bergquist, Robert and Utzinger, Jürg and Keiser, Jennifer. (2017) Controlling schistosomiasis with praziquantel : how much longer without a viable alternative? Infectious Diseases of Poverty, 6. p. 74.

Cowan, Noemi and Meier, Charles and Neodo, Anna and Keiser, Jennifer. (2017) Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes. International journal for parasitology. Drugs and drug resistance, 7 (2). pp. 159-173.

Sayasone, Somphou and Meister, Isabel and Andrews, Jason R. and Odermatt, Peter and Vonghachack, Youthanavanh and Xayavong, Syda and Senggnam, Kanpaseuth and Phongluxa, Khampheng and Hattendorf, Jan and Bogoch, Isaac I. and Keiser, Jennifer. (2017) Efficacy and safety of praziquantel against light infections of Opisthorchis viverrini : a randomised parallel single blind dose-ranging trial. Clinical infectious diseases, 64 (4). pp. 451-458.

Coulibaly, Jean T. and Panic, Gordana and Silué, Kigbafori D. and Kovac, Jana and Hattendorf, Hattendorf and Keiser, Jennifer. (2017) Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose-ranging, phase 2 trial. Lancet Glob Health, 5 (7). e688-e698.

Tritten, Lucienne and Tam, Mifong and Vargas, Mireille and Jardim, Armando and Stevenson, Mary M. and Keiser, Jennifer and Geary, Timothy G.. (2017) Excretory/secretory products from the gastrointestinal nematode Trichuris muris. Experimental parasitology, 178. pp. 30-36.

Okombo, John and Singh, Kawaljit and Mayoka, Godfrey and Ndubi, Ferdinand and Barnard, Linley and Njogu, Peter M. and Njoroge, Mathew and Gibhard, Liezl and Brunschwig, Christel and Vargas, Mireille and Keiser, Jennifer and Egan, Timothy J. and Chibale, Kelly. (2017) Antischistosomal activity of pyrido[1,2-a]benzimidazole derivatives and correlation with inhibition of beta-hematin formation. ACS Infectious Diseases, 3 (6). pp. 411-420.

Rajchgot, Jason and Coulibaly, Jean T. and Keiser, Jennifer and Utzinger, Jürg and Lo, Nathan C. and Mondry, Michael K. and Andrews, Jason R. and Bogoch, Isaac I.. (2017) Mobile-phone and handheld microscopy for neglected tropical diseases. PLoS neglected tropical diseases, 11 (7). e0005550.

Kovač, Jana and Vargas, Mireille and Keiser, Jennifer. (2017) In vitro and in vivo activity of R- and S- praziquantel enantiomers and the main human metabolite trans-4-hydroxy-praziquantel against Schistosoma haematobium. Parasites and Vectors, 10. p. 365.

Preston, Sarah and Jiao, Yaqing and Baell, Jonathan B. and Keiser, Jennifer and Crawford, Simon and Koehler, Anson V. and Wang, Tao and Simpson, Moana M. and Kaplan, Ray M. and Cowley, Karla J. and Simpson, Kaylene J. and Hofmann, Andreas and Jabbar, Abdul and Gasser, Robin B.. (2017) Screening of the 'Open Scaffolds' collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the barber's pole worm and other parasitic nematodes. International Journal for Parasitology: Drugs and Drug Resistance, 7 (3). pp. 286-294.

Greter, Helena and Cowan, Noemi and Ngandolo, Bongo N. and Kessely, Hamit and Alfaroukh, Idriss O. and Utzinger, Jürg and Keiser, Jennifer and Zinsstag, Jakob. (2017) Treatment of human and livestock helminth infections in a mobile pastoralist setting at Lake Chad: attitudes to health and analysis of active pharmaceutical ingredients of locally available anthelminthic drugs. Acta Tropica, 175. pp. 91-99.

Abla, Nada and Keiser, Jennifer and Vargas, Mireille and Reimers, Natalie and Haas, Helmut and Spangenberg, Thomas. (2017) Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model. PLoS neglected tropical diseases, 11 (9). e0005942.

Barda, Beatrice and Albonico, Marco and Buonfrate, Dora and Ame, Shaali M. and Ali, Said and Speich, Benjamin and Keiser, Jennifer. (2017) Side benefits of mass drug administration for lymphatic filariasis on Strongyloides stercoralis prevalence on Pemba Island, Tanzania. American journal of tropical medicine and hygiene, 97 (3). pp. 681-683.

Barda, Beatrice and Sayasone, Somphou and Phongluxa, Khampheng and Xayavong, Syda and Keoduangsy, Khonsavanh and Odermatt, Peter and Puchkov, Maxim and Huwyler, Jörg and Hattendorf, Jan and Keiser, Jennifer. (2017) Efficacy of moxidectin versus ivermectin against Strongyloides stercoralis infections: a randomized controlled noninferiority trial. Clinical Infectious Diseases, 65 (2). pp. 276-281.

Panic, Gordana and Ruf, Marie-Thérèse and Keiser, Jennifer. (2017) Immunohistochemical investigations of treatment with Ro 13-3978, praziquantel, oxamniquine, and mefloquine in Schistosoma mansoni-infected mice. Antimicrobial agents and chemotherapy, 61 (12). e01142-17.

Hess, Jeannine and Panic, Gordana and Patra, Malay and Mastrobuoni, Luciano and Spingler, Bernhard and Roy, Saonli and Keiser, Jennifer and Gasser, Gilles. (2017) Ferrocenyl, ruthenocenyl, and benzyl oxamniquine derivatives with cross-species activity against Schistosoma mansoni and Schistosoma haematobium. ACS infectious diseases, 3 (9). pp. 645-652.

Moser, Wendelin and Schindler, Christian and Keiser, Jennifer. (2017) Efficacy of recommended drugs against soil transmitted helminths: systematic review and network meta-analysis. BMJ, 358. j4307.

Perissutti, Beatrice and Passerini, Nadia and Trastullo, Ramona and Keiser, Jennifer and Zanolla, Debora and Zingone, Guglielmo and Voinovich, Dario and Albertini, Beatrice. (2017) An explorative analysis of process and formulation variables affecting comilling in a vibrational mill: the case of praziquantel. International journal of pharmaceutics, 533 (2). pp. 402-412.

Bogoch, Isaac I. and Sayasone, Somphou and Vonghachack, Youthanavanh and Meister, Isabel and Utzinger, Jürg and Odermatt, Peter and Andrews, Jason R. and Keiser, Jennifer. (2016) Diagnosis of Opisthorchis viverrini infection with handheld microscopy in Lao People's Democratic Republic. American journal of tropical medicine and hygiene, 94 (1). pp. 158-160.

Flores, Dayana and Panic, Gordana and Braissant, Olivier and Keiser, Jennifer. (2016) A novel isothermal microcalorimetry tool to assess drug effects on Ancylostoma ceylanicum and Necator americanus. Applied microbiology and biotechnology, 100 (2). pp. 837-846.

Meister, Isabel and Leonidova, Anna and Kovač, Jana and Duthaler, Urs and Keiser, Jennifer and Huwyler, Jörg. (2016) Development and validation of an enantioselective LC-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in human plasma, blood and dried blood spots. Journal of pharmaceutical and biomedical analysis, 118. pp. 81-88.

Speich, Benjamin and Moser, Wendelin and Ali, Said M. and Ame, Shaali M. and Albonico, Marco and Hattendorf, Jan and Keiser, Jennifer. (2016) Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole, albendazole-oxantel pamoate and mebendazole. Parasites and Vectors, 9. p. 123.

Qian, Men-Bao and Utzinger, Jürg and Keiser, Jennifer and Zhou, Xiao-Nong. (2016) Clonorchiasis. Lancet, 387 (10020). pp. 800-810.

Meister, Isabel and Kovac, Jana and Duthaler, Urs and Odermatt, Peter and Huwyler, Jörg and Vanobberghen, Fiona and Sayasone, Somphou and Keiser, Jennifer. (2016) Pharmacokinetic study of praziquantel enantiomers and its main metabolite R-trans-4-OH-PZQ in plasma, blood and dried blood spots in Opisthorchis viverrini-infected patients. PLoS Neglected Tropical Diseases, 10 (5). e0004700.

Cordey, S. and Brito, F. and Vu, D. L. and Turin, L. and Kilowoko, M. and Kyungu, E. and Genton, B. and Zdobnov, E. M. and D'Acremont, V. and Kaiser, L.. (2016) Astrovirus VA1 identified by next-generation sequencing in a nasopharyngeal specimen of a febrile Tanzanian child with acute respiratory disease of unknown etiology. Emerging microbes and infections, 5 (7). e67.

Coulibaly, Jean T. and Ouattara, Mamadou and D'Ambrosio, Michael V. and Fletcher, Daniel A. and Keiser, Jennifer and Utzinger, Jürg and N'Goran, Eliézer K. and Andrews, Jason R. and Bogoch, Isaac I.. (2016) Accuracy of Mobile Phone and Handheld Light Microscopy for the Diagnosis of Schistosomiasis and Intestinal Protozoa Infections in Côte d’Ivoire. PLoS Neglected Tropical Diseases, 10 (6). e0004768.

Keiser, Jennifer and Panic, Gordana and Adelfio, Roberto and Cowan, Noemi and Vargas, Mireille and Scandale, Ivan. (2016) Evaluation of an FDA approved library against laboratory models of human intestinal nematode infections. Parasites and Vectors, 9. p. 376.

Barda, Beatrice and Coulibaly, Jean T. and Puchkov, Maxim and Huwyler, Jörg and Hattendorf, Jan and Keiser, Jennifer. (2016) Efficacy and safety of moxidectin, synriam, synriam-praziquantel versus praziquantel against schistosoma haematobium and S. mansoni infections: a randomized, exploratory phase 2 trial. PLoS Neglected Tropical Diseases, 10 (9). e0005008.

Coulibaly, Jean T. and Ouattara, Mamadou and Becker, Sören L. and Lo, Nathan C. and Keiser, Jennifer and N'Goran, Eliézer K. and Ianniello, Davide and Rinaldi, Laura and Cringoli, Giuseppe and Utzinger, Jürg. (2016) Comparison of sensitivity and faecal egg counts of Mini-FLOTAC using fixed stool samples and Kato-Katz technique for the diagnosis of Schistosoma mansoni and soil-transmitted helminths. Acta tropica, 164. pp. 107-116.

Albonico, Marco and Becker, Sören L. and Odermatt, Peter and Angheben, Andrea and Anselmi, Mariella and Amor, Arancha and Barda, Beatrice and Buonfrate, Dora and Cooper, Philip and Gétaz, Laurent and Keiser, Jennifer and Khieu, Virak and Montresor, Antonio and Muñoz, José and Requena-Méndez, Ana and Savioli, Lorenzo and Speare, Richard and Steinmann, Peter and van Lieshout, Lisette and Utzinger, Jürg and Bisoffi, Zeno. (2016) StrongNet: An International Network to Improve Diagnostics and Access to Treatment for Strongyloidiasis Control. PLoS Neglected Tropical Diseases, 10 (9). e0004898.

Vanobberghen, Fiona and Penny, Melissa A. and Duthaler, Urs and Odermatt, Peter and Sayasone, Somphou and Keiser, Jennifer and Tarning, Joel. (2016) Population pharmacokinetic modeling of tribendimidine metabolites in opisthorchis viverrini-Infected adults. Antimicrobial agents and chemotherapy, 60 (10). pp. 5695-5704.

Sayasone, Somphou and Odermatt, Peter and Vonghachack, Youthanavanh and Xayavong, Syda and Senggnam, Kanpaseuth and Duthaler, Urs and Akkhavong, Kongsap and Hattendorf, Jan and Keiser, Jennifer. (2016) Efficacy and safety of tribendimidine against Opisthorchis viverrini : two randomised, parallel-group, single-blind, dose-ranging, phase 2 trials. Lancet Infectious Diseases, 16 (10). pp. 1145-1453.

Coulibaly, Jean T. and Ouattara, Mamadou and Keiser, Jennifer and Bonfoh, Bassirou and N'Goran, Eliézer K. and Andrews, Jason R. and Bogoch, Isaac I.. (2016) Evaluation of malaria diagnoses using a handheld light microscope in a community-based setting in rural Côte d'Ivoire. American journal of tropical medicine and hygiene, 95 (4). pp. 831-834.

Cowan, Noemi and Raimondo, Alessia and Keiser, Jennifer. (2016) Approved oncology drugs lack in vivo activity against Trichuris muris despite in vitro activity. Parasitology research, 115 (11). pp. 4443-4446.

Lo, Nathan C. and Coulibaly, Jean T. and Bendavid, Eran and N'Goran, Eliézer K. and Utzinger, Jürg and Keiser, Jennifer and Bogoch, Isaac I. and Andrews, Jason R.. (2016) Evaluation of a urine pooling strategy for the rapid and cost-efficient prevalence classification of schistosomiasis. PLoS Neglected Tropical Diseases, 10 (8). e0004894.

Van Voorhis, Wesley C. and Adams, John H. and Adelfio, Roberto and Ahyong, Vida and Akabas, Myles H. and Alano, Pietro and Alday, Aintzane and Alemán Resto, Yesmalie and Alsibaee, Aishah and Alzualde, Ainhoa and Andrews, Katherine T. and Avery, Simon V. and Avery, Vicky M. and Ayong, Lawrence and Baker, Mark and Baker, Stephen and Ben Mamoun, Choukri and Bhatia, Sangeeta and Bickle, Quentin and Bounaadja, Lotfi and Bowling, Tana and Bosch, Jürgen and Boucher, Lauren E. and Boyom, Fabrice F. and Brea, Jose and Brennan, Marian and Burton, Audrey and Caffrey, Conor R. and Camarda, Grazia and Carrasquilla, Manuela and Carter, Dee and Belen Cassera, Maria and Chih-Chien Cheng, Ken and Chindaudomsate, Worathad and Chubb, Anthony and Colon, Beatrice L. and Colón-López, Daisy D. and Corbett, Yolanda and Crowther, Gregory J. and Cowan, Noemi and D'Alessandro, Sarah and Le Dang, Na and Delves, Michael and DeRisi, Joseph L. and Du, Alan Y. and Duffy, Sandra and Abd El-Salam El-Sayed, Shimaa and Ferdig, Michael T. and Fernández Robledo, José A. and Fidock, David A. and Florent, Isabelle and Fokou, Patrick V. T. and Galstian, Ani and Gamo, Francisco Javier and Gokool, Suzanne and Gold, Ben and Golub, Todd and Goldgof, Gregory M. and Guha, Rajarshi and Guiguemde, W. Armand and Gural, Nil and Guy, R. Kiplin and Hansen, Michael A. E. and Hanson, Kirsten K. and Hemphill, Andrew and Hooft van Huijsduijnen, Rob and Horii, Takaaki and Horrocks, Paul and Hughes, Tyler B. and Huston, Christopher and Igarashi, Ikuo and Ingram-Sieber, Katrin and Itoe, Maurice A. and Jadhav, Ajit and Naranuntarat Jensen, Amornrat and Jensen, Laran T. and Jiang, Rays H. Y. and Kaiser, Annette and Keiser, Jennifer and Ketas, Thomas and Kicka, Sebastien and Kim, Sunyoung and Kirk, Kiaran and Kumar, Vidya P. and Kyle, Dennis E. and Lafuente, Maria Jose and Landfear, Scott and Lee, Nathan and Lee, Sukjun and Lehane, Adele M. and Li, Fengwu and Little, David and Liu, Liqiong and Llinás, Manuel and Loza, Maria I. and Lubar, Aristea and Lucantoni, Leonardo and Lucet, Isabelle and Maes, Louis and Mancama, Dalu and Mansour, Nuha R. and March, Sandra and McGowan, Sheena and Medina Vera, Iset and Meister, Stephan and Mercer, Luke and Mestres, Jordi and Mfopa, Alvine N. and Misra, Raj N. and Moon, Seunghyun and Moore, John P. and Morais Rodrigues da Costa, Francielly and Müller, Joachim and Muriana, Arantza and Nakazawa Hewitt, Stephen and Nare, Bakela and Nathan, Carl and Narraidoo, Nathalie and Nawaratna, Sujeevi and Ojo, Kayode K. and Ortiz, Diana and Panic, Gordana and Papadatos, George and Parapini, Silvia and Patra, Kailash and Pham, Ngoc and Prats, Sarah and Plouffe, David M. and Poulsen, Sally-Ann and Pradhan, Anupam and Quevedo, Celia and Quinn, Ronald J. and Rice, Christopher A. and Abdo Rizk, Mohamed and Ruecker, Andrea and St Onge, Robert and Salgado Ferreira, Rafaela and Samra, Jasmeet and Robinett, Natalie G. and Schlecht, Ulrich and Schmitt, Marjorie and Silva Villela, Filipe and Silvestrini, Francesco and Sinden, Robert and Smith, Dennis A. and Soldati, Thierry and Spitzmüller, Andreas and Stamm, Serge Maximilian and Sullivan, David J. and Sullivan, William and Suresh, Sundari and Suzuki, Brian M. and Suzuki, Yo and Swamidass, S. Joshua and Taramelli, Donatella and Tchokouaha, Lauve R. Y. and Theron, Anjo and Thomas, David and Tonissen, Kathryn F. and Townson, Simon and Tripathi, Abhai K. and Trofimov, Valentin and Udenze, Kenneth O. and Ullah, Imran and Vallieres, Cindy and Vigil, Edgar and Vinetz, Joseph M. and Voong Vinh, Phat and Vu, Hoan and Watanabe, Nao-Aki and Weatherby, Kate and White, Pamela M. and Wilks, Andrew F. and Winzeler, Elizabeth A. and Wojcik, Edward and Wree, Melanie and Wu, Wesley and Yokoyama, Naoaki and Zollo, Paul H. A. and Abla, Nada and Blasco, Benjamin and Burrows, Jeremy and Laleu, Benoît and Leroy, Didier and Spangenberg, Thomas and Wells, Timothy and Willis, Paul A.. (2016) Open source drug discovery with the malaria box compound collection for neglected diseases and beyond. PLoS Pathogens, 12 (7). e1005763.

Duthaler, Urs and Sayasone, Somphou and Vanobbergen, Fiona and Penny, Melissa A. and Odermatt, Peter and Huwyler, Jörg and Keiser, Jennifer. (2016) Single ascending dose pharmacokinetic study of tribendimidine in Opisthorchis viverrini-infected patients. Antimicrobial agents and chemotherapy, 60 (10). pp. 5705-5715.

Khan, M. O. Faruk and Keiser, Jennifer and Amoyaw, P. N. A. and Hossain, Mohammad F. and Vargas, Mireille and Le, Justin G. and Simpson, Natalie C. and Roewe, Kimberly D. and Freeman, TaRynn N. Carder and Hasley, Travis R. and Maples, Randall D. and Archibald, Stephen J. and Hubin, Timothy J.. (2016) Discovery of antischistosomal drug leads based on tetraazamacrocyclic derivatives and their metal complexes. Antimicrobial agents and chemotherapy, 60 (9). pp. 5331-5336.

Clède, Sylvain and Cowan, Noemi and Lambert, François and Bertrand, Hélène C. and Rubbiani, Riccardo and Patra, Malay and Hess, Jeannine and Sandt, Christophe and Trcera, Nicolas and Gasser, Gilles and Keiser, Jennifer and Policar, Clotilde. (2016) Bimodal x-ray and infrared imaging of an organometallic derivative of praziquantel in Schistosoma mansoni. ChemBioChem, 17 (11). pp. 1004-1007.

Wang, Chunkai and Zhao, Qingjie and Vargas, Mireille and Jones, Jeremy O. and White, Karen L. and Shackleford, David M. and Chen, Gong and Saunders, Jessica and Ng, Alice C. F. and Chiu, Francis C. K. and Dong, Yuxiang and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2016) Revisiting the SAR of the antischistosomal aryl hydantoin (Ro 13-3978). Journal of medicinal chemistry, 59 (23). pp. 10705-10718.

Greter, Helena and Batil, Annour A. and Alfaroukh, Idriss O. and Grimm, Felix and Ngandolo, Bongo N. and Keiser, Jennifer and Utzinger, Jürg and Zinsstag, Jakob and Hattendorf, Jan. (2016) Re-infection with Fasciola gigantica 6-months post-treatment with triclabendazole in cattle from mobile pastoralist husbandry systems at Lake Chad. Veterinary parasitology, 230. pp. 43-48.

Leonidova, Anna and Vargas, Mireille and Huwyler, Jörg and Keiser, Jennifer. (2016) Pharmacokinetics of the antischistosomal lead OZ418 in uninfected mice determined by LC-MS/MS. Antimicrobial agents and chemotherapy, 60 (12). pp. 7364-7371.

Keiser, Jenifer and [et al.], . (2015) Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infection : a four-arm, randomised controlled trial. The Lancet infectious diseases, Vol. 15, H. 3. pp. 277-284.

Braissant, Olivier and Keiser, Jennifer and Meister, Isabel and Bachmann, Alexander and Wirz, Dieter and Göpfert, Beat and Bonkat, Gernot and Wadsö, Ingemar. (2015) Isothermal microcalorimetry accurately detects bacteria, tumorous microtissues, and parasitic worms in a label-free well-plate assay. Biotechnology journal, 10 (3). pp. 460-468.

Speich, Benjamin and Ali, Said M. and Ame, Shaali M. and Albonico, Marco and Utzinger, Jürg and Keiser, Jennifer. (2015) Quality control in the diagnosis of Trichuris trichiura and Ascaris lumbricoides using the Kato-Katz technique : experience from three randomised controlled trials. Parasites and Vectors, 8 (82).

Ogorodova, Ludmila M. and Fedorova, Olga S. and Sripa, Banchob and Mordvinov, Viatcheslav A. and Katokhin, Aleksei V. and Keiser, Jennifer and Odermatt, Peter and Brindley, Paul J. and Mayboroda, Oleg A. and Velavan, Thirumalaisamy P. and Freidin, Maxim B. and Sazonov, Alexey E. and Saltykova, Irina V. and Pakharukova, Mariya Y. and Kovshirina, Yulia V. and Kaloulis, Kostas and Krylova, Olga Y. and Yazdanbakhsh, Maria and Topic Consortium, . (2015) Opisthorchiasis: an overlooked danger. PLoS neglected tropical diseases, Vol. 9, H. 4 , e0003563.

Barda, Beatrice and Albonico, Marco and Ianniello, Davide and Ame, Shaali M. and Keiser, Jennifer and Speich, Benjamin and Rinaldi, Laura and Cringoli, Giuseppe and Burioni, Roberto and Montresor, Antonio and Utzinger, Jürg. (2015) How long can stool samples be fixed for an accurate diagnosis of soil-transmitted helminth infection using mini-FLOTAC? PLoS neglected tropical diseases, Vol. 9, H. 4 , e0003698.

Hess, Jeannine and Keiser, Jennifer and Gasser, Gilles. (2015) Toward organometallic antischistosomal drug candidates. Future medicinal chemistry, Vol. 7, H. 6. pp. 821-830.

Keiser, Jennifer and Panic, Gordana and Vargas, Mireille and Wang, Chunkai and Dong, Yuxiang and Gautam, Nagsen and Vennerstrom, Jonathan L.. (2015) Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal. The journal of antimicrobial chemotherapy, Vol. 70, H. 6. pp. 1788-1797.

Olliaro, Piero L. and Vaillant, Michel and Diawara, Aïssatou and Coulibaly, Jean T. and Garba, Amadou and Keiser, Jennifer and King, Charles H. and Knopp, Stefanie and Landouré, Aly and N'Goran, Eliézer K. and Raso, Giovanna and Scherrer, Alexandra U. and Sousa-Figueiredo, José Carlos and Stete, Katarina and Zhou, Xiao-Nong and Utzinger, Jürg. (2015) Toward measuring Schistosoma response to praziquantel treatment with appropriate descriptors of egg excretion. PLoS neglected tropical diseases, Vol. 9, H. 6 , e0003821.

Vejzagić, Nermina and Adelfio, Roberto and Keiser, Jennifer and Kringel, Helene and Thamsborg, Stig Milan and Kapel, Christian M. O.. (2015) Bacteria-induced egg hatching differs for Trichuris muris and Trichuris suis. Parasites and Vectors, 8 (371).

Ephraim, Richard K. D. and Duah, Evans and Cybulski, James S. and Prakash, Manu and D'Ambrosio, Michael V. and Fletcher, Daniel A. and Keiser, Jennifer and Andrews, Jason R. and Bogoch, Isaac I.. (2015) Diagnosis of Schistosoma haematobium infection with a mobile phone-mounted foldscope and a reversed-lens CellScope in Ghana. American journal of tropical medicine and hygiene, Vol. 92, H. 6. pp. 1253-1256.

Cowan, Noemi and Keiser, Jennifer. (2015) Repurposing of anticancer drugs: in vitro and in vivo activities against Schistosoma mansoni. Parasites and Vectors, 8. p. 417.

Panic, Gordana and Vargas, Mireille and Scandale, Ivan and Keiser, Jennifer. (2015) Activity profile of an FDA-approved compound library against Schistosoma mansoni. PLoS neglected tropical diseases, Vol. 9, H. 7 , e0003962.

Cowan, Noemi and Yaremenko, Ivan A. and Krylov, Igor B. and Terent'ev, Alexander O. and Keiser, Jennifer. (2015) Elucidation of the in vitro and in vivo activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic monoperoxides, silyl peroxides, and hydroxylamine derivatives against Schistosoma mansoni. Bioorganic & medicinal chemistry, 23 (16). pp. 5175-5181.

Keiser, Jennifer. (2015) Is caenorhabditis elegans the magic bullet for anthelminthic drug discovery? Trends in parasitology, Vol. 31, H. 10. pp. 455-456.

Duthaler, Urs and Keiser, Jennifer and Huwyler, Jörg. (2015) LC-MS/MS method for the determination of two metabolites of tribendimidine, deacylated amidantel and its acetylated metabolite in plasma, blood and dried blood spots. Journal of Pharmaceutical and Biomedical Analysis, 105. pp. 163-173.

Moser, Wendelin and Ali, Said M. and Ame, Shaali M. and Speich, Benjamin and Puchkov, Maxim and Huwyler, Jörg and Albonico, Marco and Hattendorf, Jan and Keiser, Jennifer. (2015) Efficacy and safety of oxantel pamoate in school-aged children infected with Trichuris trichiura on Pemba Island, Tanzania: a parallel, randomised, controlled, dose-ranging study. The Lancet infectious diseases, 16 (1). pp. 53-60.

Panic, Gordana and Flores, Dayana and Ingram-Sieber, Katrin and Keiser, Jennifer. (2015) Fluorescence/luminescence-based markers for the assessment of Schistosoma mansoni schistosomula drug assays. Parasites and Vectors, 8. p. 624.

Barda, B. D. and Keiser, J. and Albonico, M.. (2015) Human trichuriasis : diagnostics update. Current tropical medicine reports, 2. pp. 201-208.

Speich, Benjamin and Ame, Shaali M. and Ali, Said M. and Alles, Rainer and Huwyler, Jörg and Hattendorf, Jan and Utzinger, Jürg and Albonico, Marco and Keiser, Jennifer. (2014) Oxantel pamoate-albendazole for Trichuris trichiura infection. The New England journal of medicine, Vol. 370, H. 7. pp. 610-620.

Küster, Tatiana and Kriegel, Nadja and Stadelmann, Britta and Wang, Xiaofang and Dong, Yuxiang and Vennerstrom, Jonathan L. and Keiser, Jennifer and Hemphill, Andrew. (2014) Amino ozonides exhibit in vitro activity against Echinococcus multilocularis metacestodes. International journal of antimicrobial agents, Vol. 43, H. 1. pp. 40-46.

Olliaro, Piero and Delgado-Romero, Petra and Keiser, Jennifer. (2014) The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer). The journal of antimicrobial chemotherapy, Vol. 69, H. 4. pp. 863-870.

Ingram-Sieber, Katrin and Cowan, Noemi and Panic, Gordana and Vargas, Mireille and Mansour, Nuha R. and Bickle, Quentin D. and Wells, Timothy N. C. and Spangenberg, Thomas and Keiser, Jennifer. (2014) Orally active antischistosomal early leads identified from the open access malaria box. PLoS neglected tropical diseases, Vol. 8, H. 1 , e2610.

Speich, B. and Utzinger, J. and Marti, H. and Ame, S. M. and Ali, S. M. and Albonico, M. and Keiser, J.. (2014) Comparison of the Kato-Katz method and ether-concentration technique for the diagnosis of soil-transmitted helminth infections in the framework of a randomised controlled trial. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Vol. 33, H. 5. pp. 815-822.

Keiser, Jennifer and Silué, Kigbafori D. and Adiossan, Lukas K. and N'Guessan, Nicaise A. and Monsan, N'Chou and Utzinger, Jürg and N'Goran, Eliézer K.. (2014) Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium : a randomized, exploratory, open-label trial. PLoS neglected tropical diseases, Vol. 8, H. 7 , e2975.

Tritten, Lucienne and Keiser, Jennifer and Karwa, Tasneem and Utzinger, Jürg and Holmes, Elaine and Saric, Jasmina. (2014) Comparing systemic metabolic responses in mice to single or dual infection with Plasmodium berghei and Heligmosomoides bakeri. Molecular biosystems, Vol. 10, H. 9. pp. 2358-2367.

Keiser, Jennifer and Vargas, Mireille and Rubbiani, Riccardo and Gasser, Gilles and Biot, Christophe. (2014) In vitro and in vivo antischistosomal activity of ferroquine derivatives. Parasites and Vectors, 7 (424).

Meister, Isabel and Ingram-Sieber, Katrin and Cowan, Noemi and Todd, Matthew and Robertson, Murray N. and Meli, Claudia and Patra, Malay and Gasser, Gilles and Keiser, Jennifer. (2014) Activity of praziquantel enantiomers and main metabolites against Schistosoma mansoni. Antimicrobial agents and chemotherapy, Vol. 58, H. 9. pp. 5466-5472.

Wang, Chunkai and Zhao, Qingjie and Min, Jaeki and Muniyan, Sakthivel and Vargas, Mireille and Wang, Xiaofang and Dong, Yuxiang and Guy, R. Kiplin and Lin, Ming-Fong and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2014) Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978. American journal of tropical medicine and hygiene, Vol. 90, H. 6. pp. 1156-1158.

Panic, Gordana and Duthaler, Urs and Speich, Benjamin and Keiser, Jennifer. (2014) Repurposing drugs for the treatment and control of helminth infections. International journal of parasitology : drugs and drug resistance, Vol. 4. pp. 185-200.

Bogoch, Isaac I. and Coulibaly, Jean T. and Andrews, Jason R. and Speich, Benjamin and Keiser, Jennifer and Stothard, J. Russell and N'goran, Eliézer K. and Utzinger, Jürg. (2014) Evaluation of portable microscopic devices for the diagnosis of Schistosoma and soil-transmitted helminth infection. Parasitology, Vol. 141, H. 14. pp. 1811-1818.

Bogoch, Isaac I. and Andrews, Jason R. and Speich, Benjamin and Ame, Shaali M. and Ali, Said M. and Stothard, J. Russell and Utzinger, Jürg and Keiser, Jennifer. (2014) Quantitative evaluation of a handheld light microscope for field diagnosis of soil-transmitted helminth infection. American journal of tropical medicine and hygiene, Vol. 91, H. 6. pp. 1138-1141.

Spivak, Anna Yu and Keiser, Jennifer and Vargas, Mireille and Gubaidullin, Rinat R. and Nedopekina, Darya A. and Shakurova, Elvira R. and Khalitova, Rezeda R. and Odinokov, Victor N.. (2014) Synthesis and activity of new triphenylphosphonium derivatives of betulin and betulinic acid against Schistosoma mansoni in vitro and in vivo. Bioorganic & medicinal chemistry, 22 (21). pp. 6297-6304.

Kulke, Daniel and von Samson-Himmelstjerna, Georg and Miltsch, Sandra M. and Wolstenholme, Adrian J. and Jex, Aaron R. and Gasser, Robin B. and Ballesteros, Cristina and Geary, Timothy G. and Keiser, Jennifer and Townson, Simon and Harder, Achim and Krücken, Jürgen. (2014) Characterization of the Ca2+-gated and voltage-dependent k+-channel slo-1 of nematodes and its interaction with emodepside. PLoS neglected tropical diseases, Vol. 8, H. 12 , e3401.

Kljun, J. and Scott, A. J. and Rizner, T. L. and Keiser, J. and Turel, I.. (2014) Synthesis and biological evaluation of organoruthenium complexes with azole antifungal agents : first crystal structure of a tioconazole metal complex. Organometallics, Vol. 33, H. 7. pp. 1594-1601.

Keiser, J. and Tritten, L. and Silbereisen, A. and Speich, B. and Adelfio, R. and Vargas, M.. (2013) Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug. PLoS neglected tropical diseases, Vol. 7, H. 3 , e2119.

Patra, M. and Ingram, K. and Pierroz, V. and Ferrari, S. and Spingler, B. and Gasser, R. B. and Keiser, J. and Gasser, G.. (2013) [(η(6) -praziquantel)Cr(CO)(3)] derivatives with remarkable in vitro anti-schistosomal activity. Chemistry : a European journal, Vol. 19, H. 7. pp. 2232-2235.

de Moraes, J. and Keiser, J. and Ingram, K. and Nascimento, C. and Yamaguchi, L. F. and Bittencourt, C. R. and Bemquerer, M. P. and Leite, J. R. and Kato, M. J. and Nakano, E.. (2013) In vitro synergistic interaction between amide piplartine and antimicrobial peptide dermaseptin against Schistosoma mansoni schistosomula and adult worms. Current medicinal chemistry, Vol. 20, H. 2. pp. 301-309.

Speich, B. and Marti, H. and Ame, S. M. and Ali, S. M. and Bogoch, I. I. and Utzinger, J. and Albonico, M. and Keiser, J.. (2013) Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide. Parasites and Vectors, 6 (3).

Keiser, J. and Manneck, T. and Kirchhofer, C. and Braissant, O.. (2013) Isothermal microcalorimetry to study the activity of triclabendazole and its metabolites on juvenile and adult Fasciola hepatica. Experimental parasitology : EP, Vol. 133, H. 3. pp. 265-268.

Wimmersberger, David and Tritten, Lucienne and Keiser, Jennifer. (2013) Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae. Parasites and Vectors, 6 (42).

Xiao, Shu-Hua and Utzinger, Jürg and Tanner, Marcel and Keiser, Jennifer and Xue, Jian. (2013) Advances with the Chinese anthelminthic drug tribendimidine in clinical trials and laboratory investigations. Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin, 126 (2). pp. 115-126.

Bogoch, Isaac I. and Andrews, Jason R. and Speich, Benjamin and Utzinger, Jürg and Ame, Shaali M. and Ali, Said M. and Keiser, Jennifer. (2013) Mobile phone microscopy for the diagnosis of soil-transmitted helminth infections : a Proof-of-Concept Study. American journal of tropical medicine and hygiene, Vol. 88, H. 4. pp. 626-629.

Qian, M. B. and Yap, P. and Yang, Y. C. and Liang, H. and Jiang, Z. H. and Li, W. and Tan, Y. G. and Zhou, H. and Utzinger, J. and Zhou, X. N. and Keiser, J.. (2013) Efficacy and safety of tribendimidine against Clonorchis sinensis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol. 56, H. 7 , e76-e82.

Vukcevic, M. and Zorzato, F. and Keck, S. and Tsakiris, D. A. and Keiser, J. and Maizels, R. M. and Treves, S.. (2013) Gain of function in the immune system caused by a ryanodine receptor 1 mutation. Journal of cell science, 126 (15). pp. 3485-3492.

Keiser, J. and Adelfio, R. and Vargas, M. and Odermatt, P. and Tesana, S.. (2013) Activity of tribendimidine and praziquantel combination therapy against the liver fluke Opisthorchis viverrini in vitro and in vivo. Journal of helminthology, Vol. 87, H. 2. pp. 252-256.

Ingram, Katrin and Duthaler, Urs and Vargas, Mireille and Ellis, William and Keiser, Jennifer. (2013) Disposition of mefloquine and enpiroline is highly influenced by a chronic Schistosoma mansoni infection. Antimicrobial agents and chemotherapy, Vol. 57, H. 9. pp. 4506-4511.

Meister, Isabel and Duthaler, Urs and Huwyler, Jörg and Rinaldi, Laura and Bosco, Antonio and Cringoli, Giuseppe and Keiser, Jennifer. (2013) Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with Fasciola hepatica in sheep. Veterinary parasitology, Vol. 198, H. 1-2. pp. 102-110.

Tsang, A. S. and Ingram, K. and Keiser, J. and Hibbert, D. B. and Todd, M. H.. (2013) Enhancing the usefulness of cross dehydrogenative coupling reactions with a removable protecting group. Organic & biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry, Vol. 11, H. 30. pp. 4921-4924.

Knopp, Stefanie and Becker, Sören L. and Ingram, Katrin J. and Keiser, Jennifer and Utzinger, Jürg. (2013) Diagnosis and treatment of schistosomiasis in children in the era of intensified control. Expert review of anti-infective therapy, Vol. 11, H. 11. pp. 1237-1258.

Tritten, Lucienne and Keiser, Jennifer and Godejohann, Markus and Utzinger, Jürg and Vargas, Mireille and Beckonert, Olaf and Holmes, Elaine and Saric, Jasmina. (2013) Metabolic profiling framework for discovery of candidate diagnostic markers of malaria. Scientific Reports, 3. p. 2769.

Patra, Malay and Ingram, Katrin and Leonidova, Anna and Pierroz, Vanessa and Ferrari, Stefano and Robertson, Murray N. and Todd, Matthew H. and Keiser, Jennifer and Gasser, Gilles. (2013) In vitro metabolic profile and in vivo antischistosomal activity studies of (η(6)-praziquantel)Cr(CO)3 derivatives. Journal of medicinal chemistry, 56 (22). pp. 9192-9198.

Alles, R. and Puchkov, M. and Jablonski, C. and Speich, B. and Keiser, J. and Huwyler, J.. (2013) Development of oxantel tablets for pediatric clinical studies : a technical note. Journal of drug delivery science and technology, Vol. 23, H. 6. pp. 623-625.

Panic, Gordana and Ingram, Katrin and Keiser, Jennifer. (2013) Development of an in vitro drug sensitivity assay based on newly excysted larvae of Echinostoma caproni. Parasites and Vectors, 6 (237).

Patra, Malay and Joshi, Tanmaya and Pierroz, Vanessa and Ingram, Katrin and Kaiser, Marcel and Ferrari, Stefano and Spingler, Bernhard and Keiser, Jennifer and Gasser, Gilles. (2013) DMSO-mediated ligand dissociation : renaissance for biological activity of N-heterocyclic-[Ru(η(6) -arene)Cl2 ] drug candidates. Chemistry : a European journal, Vol. 19, H. 44. pp. 14768-14772.

Qian, M. B. and Yap, P. and Yang, Y. C. and Liang, H. and Jiang, Z. H. and Li, W. and Utzinger, J. and Zhou, X. N. and Keiser, J.. (2013) Accuracy of the Kato-Katz method and formalin-ether concentration technique for the diagnosis of Clonorchis sinensis, and implication for assessing drug efficacy. Parasites and Vectors, 6 (314).

Utzinger, Jürg and Keiser, Jennifer. (2013) Research and development for neglected diseases : more is still needed, and faster. Lancet global health, Vol. 1, H. 6 , e317-e318.

Duthaler, U. and Huwyler, J. and Rinaldi, L. and Cringoli, G. and Keiser, J.. (2012) Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with Fasciola hepatica. Veterinary parasitology, Vol. 186, H. 3-4. pp. 270-280.

Kirchhofer, C. and Vargas, M. and Huwyler, J. and Keiser, J.. (2012) Pharmacokinetics of the fasciocidal drug candidates MT04 and OZ78 in uninfected rats and in vitro pharmacodynamic studies. International journal for parasitology: drugs and drug resistance, Vol. 2. pp. 121-125.

Knopp, Stefanie and Steinmann, Peter and Hatz, Christoph and Keiser, Jennifer and Utzinger, Jürg. (2012) Nematode infections : filariases. Infectious disease clinics of North America, Vol. 26, H. 2. pp. 359-381.

Toyang, N. J. and Ateh, E. N. and Keiser, J. and Vargas, M. and Bach, H. and Tane, P. and Sondengam, L. B. and Davis, H. and Bryant, J. and Verpoorte, R.. (2012) Toxicity, antimicrobial and anthelmintic activities of Vernonia guineensis Benth. (Asteraceae) crude extracts. Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs, Vol. 144, H. 3. pp. 700-704.

Speich, B. and Ame, S. M. and Ali, S. M. and Alles, R. and Hattendorf, J. and Utzinger, J. and Albonico, M. and Keiser, J.. (2012) Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection : a randomized controlled trial. PLoS neglected tropical diseases, Vol. 6, H. 6 , e1685.

Lochmatter, C. and Schneider, C. L. and Ingram, K. and Keiser, J. and Schifferli, J. A.. (2012) Schistosoma mansoni tetraspanning orphan receptor (SmTOR) : a new vaccine candidate against Schistosomiasis. Clinical and experimental immunology, Vol. 170, H. 3. pp. 342-357.

Ingram, K. and Yaremenko, I. A. and Krylov, I. and Hofer, L. and Terent'ev, A. O. and Keiser, J.. (2012) Identification of antischistosomal leads by evaluating peroxides of beta-dicarbonyl compounds and their heteroanalogs : bridged 1,2,4,5-tetraoxanes and alphaperoxides, and beta,delta-triketones: tricyclic monoperoxides. Journal of medicinal chemistry, 55 (20). pp. 8700-8711.

Knopp, Stefanie and Steinmann, Peter and Keiser, Jennifer and Utzinger, Jürg. (2012) Nematode infections : soil-transmitted helminths and Trichinella. Infectious disease clinics of North America, Vol. 26, H. 2. pp. 341-358.

Utzinger, J. and Becker, S. L. and Knopp, S. and Blum, J. and Neumayr, A. L. and Keiser, J. and Hatz, C. F.. (2012) Neglected tropical diseases : diagnosis, clinical management, treatment and control. Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology, Vol. 142 , w13726.

Keiser, J. and Vargas, M. and Winter, R.. (2012) Anthelminthic properties of mangostin and mangostin diacetate. Parasitology international, Vol. 61, H. 2. pp. 369-371.

Patra, M. and Ingram, K. and Pierroz, V. and Ferrari, S. and Spingler, B. and Keiser, J. and Gasser, G.. (2012) Ferrocenyl derivatives of the anthelmintic praziquantel : design, synthesis and biological evaluation. Journal of medicinal chemistry, 55 (20). pp. 8790-8798.

Tritten, L. and Nwosu, U. and Vargas, M. and Keiser, J.. (2012) In vitro and in vivo efficacy of tribendimidine and its metabolites alone and in combination against the hookworms Heligmosomoides bakeri and Ancylostoma ceylanicum. Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin, 122 (1). pp. 101-107.

Ingram, K. and Schiaffo, C. E. and Sittiwong, W. and Benner, E. and Dussault, P. H. and Keiser, J.. (2012) In vitro and in vivo activity of 3-alkoxy-1,2-dioxolanes against Schistosoma mansoni. The journal of antimicrobial chemotherapy, Vol. 67, H. 8. pp. 1979-1986.

Keiser, J. and Tritten, L. and Adelfio, R. and Vargas, M.. (2012) Effect of combinations of marketed human anthelmintic drugs against Trichuris muris in vitro and in vivo. Parasites and Vectors, 5 (292).

Marxer, M. and Ingram, K. and Keiser, J.. (2012) Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula. Parasites and Vectors, 5 (164).

Tritten, L. and Braissant, O. and Keiser, J.. (2012) Comparison of novel and existing tools for studying drug sensitivity against the hookworm Ancylostoma ceylanicum in vitro. Parasitology, Vol. 139, H. 3. pp. 348-357.

Thomsen, H. and Reider, K. and Franke, K. and Wessjohann, L. A. and Keiser, J. and Dagne, E. and Arnold, N.. (2012) Characterization of constituents and anthelmintic properties of Hagenia abyssinica. Scientia Pharmaceutica, 80 (2). pp. 433-446.

Coulibaly, J. T. and N'Gbesso, Y. K. and Knopp, S. and Keiser, J. and N'Goran, E. K. and Utzinger, J.. (2012) Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium. PLoS neglected tropical diseases, Vol. 6, H. 12 , e1917.

Saric, J. and Want, E. J. and Duthaler, U. and Lewis, M. and Keiser, J. and Schockcor, J. P. and Ross, G. A. and Nicholson, J. K. and Holmes, E. and Tavares, M. F.. (2012) Systematic evaluation of extraction methods for multi-platform based metabotyping : application to the Fasciola hepatica metabolome. Analytical chemistry, Vol. 84, H. 16. pp. 6963-6972.

Zumla, A. and Keiser, J.. (2012) Tropical diseases. Infectious disease clinics of North America, Vol. 26, H. 2 , xv-xvii.

Manneck, T. and Keiser, J. and Müller, J.. (2012) Mefloquine interferes with glycolysis in schistosomula of Schistosoma mansoni via inhibition of enolase. Parasitology, Vol. 139, H. 4. pp. 497-505.

Ingram, K. and Ellis, W. and Keiser, J.. (2012) Antischistosomal activities of mefloquine-related arylmethanols. Antimicrobial agents and chemotherapy, Vol. 56, H. 6. pp. 3207-3215.

Tritten, Lucienne and Silbereisen, Angelika and Keiser, Jennifer. (2012) Nitazoxanide : in vitro and in vivo drug effects against Trichuris muris and Ancylostoma ceylanicum, alone or in combination. International journal for parasitology: drugs and drug resistance, Vol. 2. pp. 98-105.

Keiser, Jennifer and Utzinger, Jurg. (2012) Antimalarials in the treatment of schistosomiasis. Current pharmaceutical design, Vol. 18, H. 24. pp. 3531-3538.

Koné, W. M. and Vargas, M. and Keiser, J.. (2012) Anthelmintic activity of medicinal plants used in Côte d'Ivoire for treating parasitic diseases. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 110, H. 6. pp. 2351-2362.

Lovis, L. and Mak, T. K. and Phongluxa, K. and Soukhathammavong, P. A. and Vonghachack, Y. and Keiser, J. and Vounatsou, P. and Tanner, M. and Hatz, C. and Utzinger, J. and Odermatt, P. and Akkhavong, K.. (2012) Efficacy of praziquantel against Schistosoma mekongi and Opisthorchis viverrini : a randomized, single-blinded dose-comparison trial. PLoS neglected tropical diseases, Vol. 6, H. 7 , e1726.

Caffrey, C. R. and Utzinger, J. and Keiser, J.. (2012) Drug discovery for trematodiases : challenges and progress. In: Parasitic helminths : targets, screens, drugs and vaccines. Weinheim, pp. 323-337.

Soukhathammavong, P. A. and Sayasone, S. and Phongluxa, K. and Xayaseng, V. and Utzinger, J. and Vounatsou, P. and Hatz, C. and Akkhavong, K. and Keiser, J. and Odermatt, P.. (2012) Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR. PLoS neglected tropical diseases, Vol. 6, H. 1 , e1417.

Ziegelbauer, K. and Speich, B. and Mäusezahl, D. and Bos, R. and Keiser, J. and Utzinger, J.. (2012) Effect of sanitation on soil-transmitted helminth infection : systematic review and meta-analysis. PLoS medicine, Vol. 9, H. 1, e1001162.

Duthaler, Urs and Keiser, Jennifer and Huwyler, Jörg. (2011) Development and validation of a liquid chromatography and ion spray tandem mass spectrometry method for the quantification of artesunate, artemether, and their major metabolites dihydroartemisinin and dihydroartemisininglucuronide in sheep plasma. Journal of Mass Spectrometry, 46 (2). pp. 172-181.

Soukhathammavong, P. and Odermatt, P. and Sayasone, S. and Vonghachack, Y. and Vounatsou, P. and Hatz, C. and Akkhavong, K. and Keiser, J.. (2011) Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with Opisthorchis viverrini : a randomised, exploratory, open-label, phase 2 trial. The Lancet infectious diseases, 11 (2). pp. 110-118.

Li, J. V. and Saric, J. and Wang, Y. and Keiser, J. and Utzinger, J. and Holmes, E.. (2011) Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni. Parasites and Vectors, 4 (179).

Ferreira, J. F. and Peaden, P. and Keiser, J.. (2011) In vitro trematocidal effects of crude alcoholic extracts of Artemisia annua, A. absinthium, Asimina triloba, and Fumaria officinalis : trematocidal plant alcoholic extracts. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 109, H. 6. pp. 1585-1592.

Tritten, Lucienne and Silbereisen, Angelika and Keiser, Jennifer. (2011) In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS neglected tropical diseases, Vol. 5, H. 12 , e1457.

Nwosu, Uzoma and Vargas, Mireille and Harder, Achim and Keiser, Jennifer. (2011) Efficacy of the cyclooctadepsipeptide PF1022A against Heligmosomoides bakeri in vitro and in vivo. Parasitology, Vol. 138, H. 9. pp. 1193-1201.

Keiser, J. and Manneck, T. and Vargas, M.. (2011) Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro. The journal of antimicrobial chemotherapy, Vol. 66, H. 8. pp. 1791-1797.

Olliaro, P. and Seiler, J. and Kuesel, A. and Horton, J. and Clark, J. N. and Don, R. and Keiser, J.. (2011) Potential drug development candidates for human soil-transmitted helminthiases. PLoS neglected tropical diseases, Vol. 5, H. 6 , e1138.

Silbereisen, Angelika and Tritten, Lucienne and Keiser, Jennifer. (2011) Exploration of novel in vitro assays to study drugs against Trichuris spp. Journal of microbiological methods, Vol. 87, H. 2. pp. 169-175.

Wang, Xiaofang and Zhao, Qingjie and Vargas, Mireille and Dong, Yuxiang and Sriraghavan, Kamaraj and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2011) The activity of dispiro peroxides against Fasciola hepatica. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 21, H. 18. pp. 5320-5330.

Keiser, Jennifer and Ingram, Katrin and Utzinger, Jürg. (2011) Antiparasitic drugs for paediatrics : systematic review, formulations, pharmacokinetics, safety, efficacy and implications for control. Parasitology, Vol. 138, H. 12. pp. 1620-1632.

Küster, T. and Stadelmann, B. and Hermann, C. and Scholl, S. and Keiser, J. and Hemphill, A.. (2011) In vitro and in vivo efficacy of mefloquine-based treatment against alveolar echinococcosis. Antimicrobial agents and chemotherapy : AAC, Vol. 55, H. 2. pp. 713-721.

Manneck, T. and Braissant, O. and Ellis, W. and Keiser, J.. (2011) Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. Experimental parasitology : EP, Vol. 127, H. 1. pp. 260-269.

Manneck, T. and Braissant, O. and Haggenmüller, Y. and Keiser, J.. (2011) Isothermal microcalorimetry to study drugs against Schistosoma mansoni. Journal of clinical microbiology, Vol. 49, H. 4. pp. 1217-1225.

Kirchhofer, C. and Vargas, M. and Braissant, O. and Dong, Y. and Wang, X. and Vennerstrom, J. L. and Keiser, J.. (2011) Activity of OZ78 analogues against Fasciola hepatica and Echinostoma caproni. Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin, 118 (1). pp. 56-62.

Keiser, J. and Sayed, H. and El-Ghanam M., and Sabry, H. and Anani, S. and El-Wakeel A., and Hatz, C. and Utzinger, J. and El-Din S. S., and El-Maadawy W., and Botros, S.. (2011) Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials. PLoS neglected tropical diseases, Vol. 5, H. 9 , e1285.

Utzinger, J. and N'Goran E. K., and Caffrey, C. R. and Keiser, J.. (2011) From innovation to application: social-ecological context, diagnostics, drugs and integrated control of schistosomiasis. Acta tropica, 120 (1). S121-S137.

Stadelmann, Britta and Küster, Tatiana and Scholl, Sabrina and Barna, Fabienne and Kropf, Christian and Keiser, Jennifer and Boykin, David W. and Stephens, Chad E. and Hemphill, Andrew. (2011) In vitro efficacy of dicationic compounds and mefloquine enantiomers against Echinococcus multilocularis metacestodes. Antimicrobial agents and chemotherapy : AAC, Vol. 55, H. 10. pp. 4866-4872.

Keiser, J. and Ingram, K. and Vargas, M. and Chollet, J. and Wang, X. and Dong, Y. and Vennerstrom, J. L.. (2011) In Vivo Activity of Aryl Ozonides against Schistosoma Species. Antimicrobial agents and chemotherapy, 56 (2). pp. 1090-1092.

Keiser, J. and N'Guessan N. A., and Adoubryn, K. D. and Silué, K. D. and Vounatsou, P. and Hatz, C. and Utzinger, J. and N'Goran E. K., . (2010) Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: randomized, exploratory open-label trial. Clinical Infectious Diseases, Vol. 50, H. 9. pp. 1205-1213.

Utzinger, Jürg and Tanner, Marcel and Keiser, Jennifer. (2010) ACTs for schistosomiasis: do they act? The Lancet infectious diseases, Vol. 10, H. 9. pp. 579-581.

Xiao, S. H. and Keiser, J. and Chen, M. G. and Tanner, M. and Utzinger, J.. (2010) Research and development of antischistosomal drugs in the People's Republic of China a 60-year review. Advances in parasitology, Vol. 73. pp. 231-295.

Keiser, Jennifer and Kirchhofer, Carla and Haschke, Manuel and Huwyler, Jörg and Dong, Yuxiang and Vennerstrom, Jonathan L. and Vanhoff, Kathleen and Kaminsky, Ronald and Malikides, Nick. (2010) Efficacy, safety and pharmacokinetics of 1,2,4-trioxolane OZ78 against an experimental infection with Fasciola hepatica in sheep. Veterinary parasitology, Vol. 173, H. 3-4. pp. 228-235.

Kirchhofer, C. and Keiser, J. and Huwyler, J.. (2010) Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate. Journal of chromatography B, 878 (28). pp. 2770-2774.

Keiser, Jennifer and Vargas, Mireille and Doenhoff, Michael J.. (2010) Activity of artemether and mefloquine against juvenile and adult Schistosoma mansoni in athymic and immunocompetent NMRI mice. American Journal of Tropical Medicine and Hygiene, Vol. 82, H. 1. pp. 112-114.

Keiser, Jennifer and Veneziano, Vincenzo and Rinaldi, Laura and Mezzino, Laura and Duthaler, Urs and Cringoli, Giuseppe. (2010) Anthelmintic activity of artesunate against Fasciola hepatica in naturally infected sheep. Research in Veterinary Science, Vol. 88, H. 1. pp. 107-110.

Dong, Y. and Chollet, J. and Vargas, M. and Mansour, N. R. and Bickle, Q. and Alnouti, Y. and Huang, J. and Keiser, J. and Vennerstrom, J. L.. (2010) Praziquantel analogs with activity against juvenile Schistosoma mansoni. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 20, H. 8. pp. 2481-2484.

Keiser, J. and Vargas, M. and Vennerstrom, J. L.. (2010) Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice. The journal of antimicrobial chemotherapy, Vol. 65, H. 9. pp. 1991-1995.

Rufener, L. and Keiser, J. and Kaminsky, R. and Mäser, P. and Nilsson, D.. (2010) Phylogenomics of ligand-gated ion channels predicts monepantel effect. PLoS Pathogens, Vol. 6, H. 9 , e1001091.

Duthaler, U. and Smith, T. A. and Keiser, J.. (2010) In vivo and in vitro sensitivity of Fasciola hepatica to combinations of triclabendazole and artesunate, artemether or OZ78. Antimicrobial agents and chemotherapy : AAC, Vol. 54, H. 11. pp. 4596-4604.

Wang, Y. and Li, J. V. and Saric, J. and Keiser, J. and Wu, J. and Utzinger, J. and Holmes, E.. (2010) Advances in metabolic profiling of experimental nematode and trematode infections. Advances in parasitology, Vol. 73. pp. 373-404.

Manneck, T. and Haggenmüller, Y. and Keiser, J.. (2010) Morphological effects and tegumental alterations induced by mefloquine on schistosomula and adult flukes of Schistosoma mansoni. Parasitology, Vol. 137, H. 1. pp. 85-98.

Keiser, Jennifer and Vargas, Mireille. (2010) Effect of artemether, artesunate, OZ78, praziquantel, and tribendimidine alone or in combination chemotherapy on the tegument of Clonorchis sinensis. Parasitology international, Vol. 59, H. 3. pp. 472-476.

Zhao, Qingjie and Vargas, Mireille and Dong, Yuxiang and Zhou, Lin and Wang, Xiaofang and Sriraghavan, Kamaraj and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2010) Structure-activity relationship of an ozonide carboxylic acid (OZ78) against Fasciola hepatica. Journal of medicinal chemistry, 53 (10). pp. 4223-4233.

Duthaler, U. and Rinaldi, L. and Maurelli, M. P. and Vargas, M. and Utzinger, J. and Cringoli, G. and Keiser, J.. (2010) Fasciola hepatica: comparison of the sedimentation and FLOTAC techniques for the detection and quantification of faecal egg counts in rats. Experimental parasitology : EP, Vol. 126, H. 2. pp. 161-166.

Saric, Jasmina and Li, Jia V. and Utzinger, Jürg and Wang, Yulan and Keiser, Jennifer and Dirnhofer, Stephan and Beckonert, Olaf and Sharabiani, Mansour T. A. and Fonville, Judith M. and Nicholson, Jeremy K. and Holmes, Elaine. (2010) Systems parasitology: effects of Fasciola hepatica on the neurochemical profile in the rat brain. Molecular systems biology, Vol. 6 , 396.

Utzinger, J. and Keiser, J. and Albonico, M.. (2010) This wormy world : here and there and everywhere. Parassitologia : organo ufficiale della Società Italiana di Parassitologia, Vol. 52. pp. 47-50.

Utzinger, J. and Steinmann, P. and Keiser, J. and Bos, R.. (2010) Impacts santaires du développement des larges réserves d'eau, barrages et irrigation. In: Écologie de la santé et biodiversité : cours. Bruxelles, pp. 116-125.

Keiser, J.. (2010) In vitro and in vivo trematode models for chemotherapeutic studies. Parasitology, 137 (3). pp. 589-603.

Keiser, Jennifer and Duthaler, Urs and Utzinger, Jürg. (2010) Update on the diagnosis and treatment of food-borne trematode infections. Current opinion in infectious diseases, 23 (5). pp. 513-520.

Keiser, Jennifer and Utzinger, Jürg. (2010) The drugs we have and the drugs we need against major helminth infections. Advances in parasitology, Vol. 73. pp. 197-230.

Caffrey, C. R. and Williams, D. L. and Todd, M. J. and Nelson, D. L. and Keiser, J. and Utzinger, J. and Selzer, P. M.. (2009) Chemotherapeutic development strategies for schistosomiasis. In: Antiparasitic and Antibacterial drug discovery. Weinheim, pp. 301-321.

Hodel, E. M. and Zanolari, B. and Mercier, T. and Biollaz, J. and Keiser, J. and Olliaro, P. and Genton, B. and Decosterd, L. A.. (2009) A single LC-tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Vol. 877, H. 10. pp. 867-886.

Keiser, J. and Odermatt, P. and Tesana, S.. (2009) Dose-response relationships and tegumental surface alterations in Opisthorchis viverrini following treatment with mefloquine in vivo and in vitro. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 105, H. 1. pp. 261-266.

Lovis, L. and Mak, T. K. and Phongluxa, K. and Soukhathammavong, P. and Sayasone, S. and Akkhavong, K. and Odermatt, P. and Keiser, J. and Felger, I.. (2009) PCR diagnosis of Opisthorchis viverrini and Haplorchis taichui infections in a Lao community in an area of endemicity and comparison of diagnostic methods for parasitological field surveys. Journal of Clinical Microbiology, Vol. 47, H. 5. pp. 1517-1523.

O'Neill J. F., and Johnston, R. C. and Halferty, L. and Brennan, G. P. and Keiser, J. and Fairweather, I.. (2009) Adult triclabendazole-resistant Fasciola hepatica: morphological changes in the tegument and gut following in vivo treatment with artemether in the rat model. Journal of Helminthology, Vol. 83, H. 2. pp. 151-163.

Halferty, L. and O'Neill, J. F. and Brennan, G. P. and Keiser, J. and Fairweather, I.. (2009) Electron microscopical study to assess the in vitro effects of the synthetic trioxolane OZ78 against the liver fluke, Fasciola hepatica. Parasitology, Vol. 136, H. 11. pp. 1325-1337.

Keiser, Jennifer and Gruyer, Marie-Stella and Perrottet, Nancy and Zanolari, Boris and Mercier, Thomas and Decosterd, Laurent. (2009) Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with Fasciola hepatica. Journal of Antimicrobial Chemotherapy, Vol. 63, H. 3. pp. 543-549.

Li, Jia V. and Holmes, Elaine and Saric, Jasmina and Keiser, Jennifer and Dirnhofer, Stephan and Utzinger, Jürg and Wang, Yulan. (2009) Metabolic profiling of a Schistosoma mansoni infection in mouse tissues using magic angle spinning-nuclear magnetic resonance spectroscopy. International journal for parasitology, Vol. 39. pp. 547-558.

Saric, J. and Li, J. V. and Wang, Y. and Keiser, J. and Veselkov, K. A. and Dirnhofer, S. and Yap, I. K. and Nicholson, J. K. and Holmes, E. and Utzinger, J.. (2009) Panorganismal metabolic response modelling of an experimental Echinostoma caproni infection in the mouse. Journal of Proteome Research, Vol. 8, H. 8. pp. 3899-3911.

Erlanger, T. E. and Weiss, S. and Keiser, J. and Utzinger, J. and Wiedenmayer, K.. (2009) Past, present, and future of Japanese encephalitis. Emerging Infectious Diseases, Vol. 15, no. 1 , 7 S..

Keiser, J. and Utzinger, J.. (2009) Food-borne trematodiases. Clinical microbiology reviews, Vol. 22. pp. 466-483.

Keiser, Jennifer and Xiao, Shu-Hua and Smith, Thomas A. and Utzinger, Jürg. (2009) Combination chemotherapy against Clonorchis sinensis : experiments with artemether, artesunate, OZ78, praziquantel, and tribendimidine in the rat model. Antimicrobial agents and chemotherapy, Vol. 53, H. 9. pp. 3770-3776.

Xiao, Shu-Hua and Keiser, Jennifer and Xue, Jian and Tanner, Marcel and Morson, Gianni and Utzinger, Jürg. (2009) Effect of single-dose oral artemether and tribendimidine on the tegument of adult Clonorchis sinensis in rats. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 104, H. 3. pp. 533-541.

Xiao, Shu-Hua and Chollet, Jacques and Utzinger, Jürg and Mei, Jin-Yan and Jiao, Pei-Yin and Keiser, Jennifer and Tanner, Marcel. (2009) Effect of single-dose oral mefloquine on the morphology of adult Schistosoma japonicum in mice. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 105, H. 3. pp. 853-861.

Zhang, Chao-Wei and Xiao, Shu-Hua and Utzinger, Jürg and Chollet, Jacques and Keiser, Jennifer and Tanner, Marcel. (2009) Histopathological changes in adult Schistosoma japonicum harbored in mice treated with a single dose of mefloquine. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 104, H. 6. pp. 1407-1416.

Keiser, J. and Chollet, J. and Xiao, S. H. and Mei, J. Y. and Jiao, P. Y. and Utzinger, J. and Tanner, M.. (2009) Mefloquine - an aminoalcohol with promising antischistosomal properties in mice. PLoS neglected tropical diseases, Vol. 3, H. 1 , e350.

Tchicaya, E. S. and Koudou, B. G. and Keiser, J. and Adja, A. M. and Cissé, G. and Tanner, M. and Tano, Y. and Utzinger, J.. (2009) Effect of repeated application of microbial larvicides on malaria transmission in central Côte d'Ivoire. Journal of the American mosquito control association : mosquito news, Vol. 25, H. 3. pp. 382-385.

Koudou, Benjamin G. and Tano, Yao and Keiser, Jennifer and Vounatsou, Penelope and Girardin, Olivier and Klero, Kouassi and Koné, Mamadou and N'goran, Eliézer K. and Cissé, Guéladio and Tanner, Marcel and Utzinger, Jürg. (2009) Effect of agricultural activities on prevalence rates, and clinical and presumptive malaria episodes in central Côte d'Ivoire. Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin = revue des sciences tropicales et de médecine tropicale = review of tropical science and tropical medicine, 111 (3). pp. 268-274.

Kim, T. I. and Yoo, W. G. and Li, S. and Hong, S. T. and Keiser, J. and Hong, S. J.. (2009) Efficacy of artesunate and artemether against Clonorchis sinensis in rabbits. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 106. pp. 153-160.

Keiser, J.. (2009) Vascular pharmacology : opportunities for intervention. Clinical pharmacology and therapeutics, Vol. 86, H. 2. pp. 124-126.

Saric, J. and Wang, Y. and Li, J. and Coen, M. and Utzinger, J. and Marchesi, J. R. and Keiser, J. and Veselkov, K. and Lindon, J. C. and Nicholson, J. K. and Holmes, E.. (2008) Species variation in the fecal metabolome gives insight into differential gastrointestinal function. Journal of Proteome Research, Vol. 7, H. 1. pp. 352-360.

Keiser, J. and Morson, G.. (2008) Fasciola hepatica: tegumental alterations in adult flukes following in vitro and in vivo administration of artesunate and artemether. Experimental parasitology : EP, Vol. 118. pp. 228-237.

Keiser, J. and Morson, G.. (2008) Fasciola hepatica: Surface tegumental responses to in vitro and in vivo treatment with the experimental fasciolicide OZ78. Experimental parasitology : EP, Vol. 119. pp. 87-93.

Xiao, S. H. and Jian, X. and Tanner, M. and Yong-Nian, Z. and Keiser, J. and Utzinger, J. and Hui-Qiang, Q.. (2008) Artemether, artesunate, praziquantel and tribendimidine administered singly at different dosages against Clonorchis sinensis : a comparative in vivo study. Acta tropica, 106 (1). pp. 54-59.

Keiser, J. and Utzinger, J. and Xiao, S. H. and Odermatt, P. and Tesana, S.. (2008) Opisthorchis viverrini : efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro. Parasitology research, Vol. 102. pp. 771-776.

Keiser, J. and Rinaldi, L. and Veneziano, V. and Mezzino, L. and Tanner, M. and Utzinger, J. and Cringoli, G.. (2008) Efficacy and safety of artemether against a natural Fasciola hepatica infection in sheep. Parasitology research, Vol. 103, H. 3. pp. 517-522.

Xue, J. and Utzinger, J. and Zhang, Y. N. and Tanner, M. and Keiser, J. and Xiao, S. H.. (2008) Artemether and tribendimidine lack activity in experimental treatment of Paragonimus westermani in the dog. Parasitology research, Vol. 102, H. 3. pp. 537-540.

Saric, J. and Li, J. V. and Wang, Y. and Keiser, J. and Bundy, J. G. and Holmes, E. and Utzinger, J.. (2008) Metabolic Profiling of an Echinostoma caproni Infection in the Mouse for Biomarker Discovery. PLoS Neglected Tropical Diseases, Vol. 2, H. 7 , e254.

Keiser, J. and Thiemann, K. and Endriss, Y. and Utzinger, J.. (2008) Strongyloides ratti : In Vitro and In Vivo Activity of Tribendimidine. PLoS neglected tropical diseases, Vol. 2, H. 1 , e136.

Spicher, M. and Roethlisberger, C. and Lany, C. and Stadelmann, B. and Keiser, J. and Ortega-Mora, L. M. and Gottstein, B. and Hemphill, A.. (2008) In vitro and in vivo treatments of echinococcus protoscoleces and metacestodes with artemisinin and artemisinin derivatives. Antimicrobial agents and chemotherapy, Vol. 52, H. 9. pp. 3447-3450.

Keiser, J. and Utzinger, J.. (2008) Efficacy of current drugs against soil-transmitted helminth infections : systematic review and meta-analysis. JAMA : the journal of the American Medical Association, Vol. 299, H. 16. pp. 1937-1948.

Erlanger, T. E. and Keiser, J. and Utzinger, J.. (2008) Effect of dengue vector control interventions on entomological parameters in developing countries : a systematic review and meta-analysis. Medical and veterinary entomology, Vol. 22, H. 3. pp. 203-221.