Items where Division is "05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Pharmazie > Molecular and Systems Toxicology (Odermatt)"
Jump to: 2023 | 2022 | 2021 | June 2020 | May 2020 | April 2020 | February 2020 | 2020 | 2019 | 2018 | 2017 | May 2016 | April 2016 | March 2016 | February 2016 | January 2016 | 2016 | December 2015 | 1 November 2015 | November 2015 | 16 October 2015 | July 2015 | June 2015 | May 2015 | April 2015 | February 2015 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2000 | 1999 Number of items at this level: 276. 2023Grötsch, Anna Deborah. Investigating the role of hexose-6-phosphate dehydrogenase in mouse metabolism and muscle function. 2023, Doctoral Thesis, University of Basel, Faculty of Science. Jäger, Marie-Christin. Pharmaceutical-induced disturbances of adrenal steroidogenesis with a focus on pseudohyperaldosteronism: Identification and characterization of potentially hazardous drugs. 2023, Doctoral Thesis, University of Basel, Faculty of Science. Keller, Morris. Isolation and characterization of anti-inflammatory and immunomodulatory compounds from higher plants. 2023, Doctoral Thesis, University of Basel, Faculty of Science. Schreier, Verena N. and Çörek, Emre and Appenzeller-Herzog, Christian and Brüschweiler, Beat J. and Geueke, Birgit and Wilks, Martin F. and Schilter, Benoit and Muncke, Jane and Simat, Thomas J. and Smie�ko, Martin and Roth, Nicolas and Odermatt, Alex. (2023) Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: A systematic evidence map. Environment international, 176. p. 107978. Servant, Raphaëlle. Patient-derived organoids to investigate drug response and treatment resistance mechanisms in prostate cancer. 2023, Doctoral Thesis, University of Basel, Faculty of Science. 2022Becker, Anna M. and Holze, Friederike and Grandinetti, Tanja and Klaiber, Aaron and Toedtli, Vanja E. and Kolaczynska, Karolina E. and Duthaler, Urs and Varghese, Nimmy and Eckert, Anne and Grünblatt, Edna and Liechti, Matthias E.. (2022) Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects. Clinical Pharmacology & Therapeutics, 111 (4). pp. 886-895. Bouitbir, Jamal and Panajatovic, Miljenko V. and Krähenbühl, Stephan. (2022) Mitochondrial Toxicity Associated with Imatinib and Sorafenib in Isolated Rat Heart Fibers and the Cardiomyoblast H9c2 Cell Line. International journal of molecular sciences, 23 (4). p. 2282. Holze, Friederike and Caluori, Toya V. and Vizeli, Patrick and Liechti, Matthias E.. (2022) Correction to: Safety pharmacology of acute LSD administration in healthy subjects. Psychopharmacology, 239 (2). p. 661. Holze, Friederike and Ley, Laura and Müller, Felix and Becker, Anna M. and Straumann, Isabelle and Vizeli, Patrick and Kuehne, Sebastian Silva and Roder, Marc A. and Duthaler, Urs and Kolaczynska, Karolina E. and Varghese, Nimmy and Eckert, Anne and Liechti, Matthias E.. (2022) Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects. Neuropsychopharmacology, 47 (6). pp. 1180-1187. Kolaczynska, Karolina E. and Luethi, Dino and Trachsel, Daniel and Hoener, Marius C. and Liechti, Matthias E.. (2022) Receptor Interaction Profiles of 4-Alkoxy-3,5-Dimethoxy-Phenethylamines (Mescaline Derivatives) and Related Amphetamines. Frontiers in Pharmacology, 12. p. 794254. Lemmens, Myriam An. Safety Assessment of Advanced Therapies for the Treatment of Human Diseases. 2022, Doctoral Thesis, University of Basel, Faculty of Science. Müller, Felix and Kraus, Elias and Holze, Friederike and Becker, Anna and Ley, Laura and Schmid, Yasmin and Vizeli, Patrick and Liechti, Matthias E. and Borgwardt, Stefan. (2022) Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants. Psychopharmacology, 239 (6). pp. 1933-1943. Roos, Noëmi Johanna and Mancuso, Riccardo Vincenzo and Sanvee, Gerda Mawududzi and Bouitbir, Jamal and Krähenbühl, Stephan. (2022) Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines. Food and Chemical Toxicology, 162. p. 112869. Schreier, Verena N. and Appenzeller-Herzog, Christian and Brüschweiler, Beat J. and Geueke, Birgit and Wilks, Martin F. and Simat, Thomas J. and Schilter, Benoit and Smiesko, Martin and Muncke, Jane and Odermatt, Alex and Roth, Nicolas. (2022) Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: Protocol for a systematic evidence map. Environment International, 167. p. 107387. Singh, Pranika. Induced Pluripotent Stem Cells in chemical safety testing- data management and bioinformatics workflows. 2022, Doctoral Thesis, University of Basel, Faculty of Science. 2021Beck, Katharina R. and Odermatt, Alex. (2021) Antifungal therapy with azoles and the syndrome of acquired mineralocorticoid excess. Molecular and Cellular Endocrinology, 524. p. 111168. Holze, Friederike and Avedisian, Isidora and Varghese, Nimmy and Eckert, Anne and Liechti, Matthias E.. (2021) Role of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin. Frontiers in Pharmacology, 12. p. 711255. Hutten, Nadia R. P. W. and Mason, Natasha L. and Dolder, Patrick C. and Theunissen, Eef L. and Holze, Friederike and Liechti, Matthias E. and Varghese, Nimmy and Eckert, Anne and Feilding, Amanda and Ramaekers, Johannes G. and Kuypers, Kim P. C.. (2021) Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers. ACS pharmacology & translational science, 4 (2). pp. 461-466. Inderbinen, Silvia G. and Zogg, Michael and Kley, Manuel and Smieško, Martin and Odermatt, Alex. (2021) Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by itraconazole and posaconazole. Toxicology and applied pharmacology, 412. p. 115387. Kolaczynska, Karolina E. and Thomann, Jan and Hoener, Marius C. and Liechti, Matthias E.. (2021) The Pharmacological Profile of Second Generation Pyrovalerone Cathinones and Related Cathinone Derivative. International journal of molecular sciences, 22 (15). p. 8277. Leclercq, Gabrielle. Cytokine release in the context of T cell bispecific antibody therapies: biological mechanisms and mitigation strategies. 2021, Doctoral Thesis, University of Basel, Faculty of Science. Liechti, Matthias E. and Holze, Friederike. (2021) Dosing Psychedelics and MDMA. Current topics in behavioral neurosciences. in press. Panajatovic, Miljenko V. and Singh, Francois and Krähenbühl, Stephan and Bouitbir, Jamal. (2021) Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression. International Journal of Molecular Siences, 22 (9). p. 4950. Ramaekers, Johannes G. and Hutten, Nadia and Mason, Natasha L. and Dolder, Patrick and Theunissen, Eef L. and Holze, Friederike and Liechti, Matthias E. and Feilding, Amanda and Kuypers, Kim P. C.. (2021) A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers. Journal of Psychopharmacology, 35 (4). pp. 398-405. Rudin, Deborah and Liechti, Matthias E. and Luethi, Dino. (2021) Molecular and clinical aspects of potential neurotoxicity induced by new psychoactive stimulants and psychedelics. Experimental Neurology, 343. p. 113778. Schnoz, Christina and Moser, Sandra and Kratschmar, Denise V. and Odermatt, Alex and Loffing-Cueni, Dominique and Loffing, Johannes. (2021) Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC. Pflügers Archiv : European journal of physiology, 473 (1). pp. 79-93. Stücheli, Simon. Investigating the Androgen Metabolizing Enzymes HSD17B6 & DHRS7 in Prostate Cancer. 2021, Doctoral Thesis, University of Basel, Faculty of Science. Vizeli, Patrick and Straumann, Isabelle and Holze, Friederike and Schmid, Yasmin and Dolder, Patrick C. and Liechti, Matthias E.. (2021) Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis. Scientific reports, 11 (1). p. 10851. Weingartner, Michael. Towards the Understanding of the Molecular and Physiological Role of Hexose-6-Phosphate Dehydrogenase. 2021, Doctoral Thesis, University of Basel, Faculty of Science. June 2020Randi, Elisa B. and Vervaet, Benjamin and Tsachaki, Maria and Porto, Elena and Vermeylen, Stijn and Lindenmeyer, Maja T. and Thuy, Le Thi Thanh and Cohen, Clemens D. and Devuyst, Olivier and Kistler, Andreas D. and Szabo, Csaba and Kawada, Norifumi and Hankeln, Thomas and Odermatt, Alex and Dewilde, Sylvia and Wenger, Roland H. and Hoogewijs, David. (2020) The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease. Antioxidants & redox signaling, 32 (16). pp. 1155-1171. May 2020Beck, Katharina R. and Telisman, Lucija and van Koppen, Chris J. and Thompson, George R. and Odermatt, Alex. (2020) Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals. The Journal of steroid biochemistry and molecular biology, 199. p. 105605. April 2020Inderbinen, Silvia G. and Engeli, Roger T. and Rohrer, Simona R. and Di Renzo, Erminio and Aengenheister, Leonie and Buerki-Thurnherr, Tina and Odermatt, Alex. (2020) Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α. Toxicology letters, 322. pp. 39-49. February 2020Patt, Melanie and Beck, Katharina R. and Di Marco, Tobias and Jäger, Marie-Christin and González-Ruiz, Victor and Boccard, Julien and Rudaz, Serge and Hartmann, Rolf W. and Salah, Mohamed and van Koppen, Chris J. and Grill, Matthias and Odermatt, Alex. (2020) Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesis. Biochemical pharmacology, 172. p. 113781. 2020Beck, Katharina R. and Thompson, George R. and Odermatt, Alex. (2020) Drug-induced endocrine blood pressure elevation. Pharmacological Research, 154. p. 104311. Becker, Claudia and Schwenkglenks, Matthias and Frueh, Mathias and Reich, Oliver and Meier, Christoph R.. (2020) Use of selective serotonin reuptake inhibitors, other antidepressant medication, and risk of cataract: a case-control study based on Swiss claims data. European Journal of Clinical Pharmacology, 76 (9). pp. 1329-1335. Davis, Matthew R. and Nguyen, Minh-Vu H. and Gintjee, Thomas J. and Odermatt, Alex and Young, Brian Y. and Thompson, George R.. (2020) Management of posaconazole-induced pseudohyperaldosteronism. Journal of Antimicrobial Chemotherapy, 75 (12). pp. 3688-3693. Grafinger, Katharina Elisabeth and Liechti, Matthias E. and Liakoni, Evangelia. (2020) Clinical value of analytical testing in patients presenting with new psychoactive substances intoxication. British Journal of Clinical Pharmacology, 86 (3). pp. 429-436. Gómez, Cristina and Stücheli, Simon and Kratschmar, Denise V. and Bouitbir, Jamal and Odermatt, Alex. (2020) Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples. Metabolites, 10 (7). p. 282. Holze, Friederike and Vizeli, Patrick and Müller, Felix and Ley, Laura and Duerig, Raoul and Varghese, Nimmy and Eckert, Anne and Borgwardt, Stefan and Liechti, Matthias E.. (2020) Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects. Neuropsychopharmacology, 45 (3). pp. 462-471. Inderbinen, Silvia. Interactions of Xenobiotics and Oxysterols with 11β-Hydroxysteroid Dehydrogenase 2 and Retinoic Acid-Related Orphan Receptor Gamma. 2020, Doctoral Thesis, University of Basel, Faculty of Science. Lizák, Beáta and Birk, Julia and Zana, Melinda and Kosztyi, Gergely and Kratschmar, Denise V. and Odermatt, Alex and Zimmermann, Richard and Geiszt, Miklós and Appenzeller-Herzog, Christian and Bánhegyi, Gábor. (2020) Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione. BMC Biology, 18 (1). p. 19. Luethi, Dino and Liechti, Matthias E.. (2020) Designer drugs: mechanism of action and adverse effects. Archives of Toxicology, 94 (4). pp. 1085-1133. Mayr, Fabian and Möller, Gabriele and Garscha, Ulrike and Fischer, Jana and Rodríguez Castaño, Patricia and Inderbinen, Silvia G. and Temml, Veronika and Waltenberger, Birgit and Schwaiger, Stefan and Hartmann, Rolf W. and Gege, Christian and Martens, Stefan and Odermatt, Alex and Pandey, Amit V. and Werz, Oliver and Adamski, Jerzy and Stuppner, Hermann and Schuster, Daniela. (2020) Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction. International Journal of Molecular Sciences, 21 (19). p. 7102. Nguyen, Minh-Vu H. and Davis, Matthew R. and Wittenberg, Rebecca and McHardy, Ian and Baddley, John W. and Young, Brian Y. and Odermatt, Alex and Thompson, George R.. (2020) Posaconazole Serum Drug Levels Associated With Pseudohyperaldosteronism. Clinical Infectious Diseases, 70 (12). pp. 2593-2598. Patt, Melanie and Gysi, Joël and Faresse, Nourdine and Cidlowski, John A. and Odermatt, Alex. (2020) Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211. Molecular and cellular endocrinology, 518. p. 110873. Potashkin, Judy and Huang, Xuemei and Becker, Claudia and Chen, Honglei and Foltynie, Thomas and Marras, Connie. (2020) Understanding the links between cardiovascular disease and Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 35 (1). pp. 55-74. Schmid, Yasmin and Scholz, Irene and Mueller, Laura and Exadaktylos, Aristomenis K. and Ceschi, Alessandro and Liechti, Matthias E. and Liakoni, Evangelia. (2020) Emergency department presentations related to acute toxicity following recreational use of cannabis products in Switzerland. Drug and Alcohol Dependence, 206. p. 107726. Schulze, Friederike and Wehner, Josua and Kratschmar, Denise V. and Makshana, Valmir and Meier, Daniel T. and Häuselmann, Stéphanie P. and Dalmas, Elise and Thienel, Constanze and Dror, Erez and Wiedemann, Sophia J. and Traub, Shuyang and Nordmann, Thierry M. and Rachid, Leila and De Baat, Axel and Rohm, Theresa V. and Zhao, Cheng and Odermatt, Alex and Böni-Schnetzler, Marianne and Donath, Marc Y.. (2020) Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes. Scientific Reports, 10 (1). p. 3035. Thompson, George R. and Surampudi, Prasanth N. and Odermatt, Alex. (2020) Gynecomastia and hypertension in a patient treated with posaconazole. Clinical case reports, 8 (12). pp. 3157-3160. Tsachaki, Maria and Strauss, Pirmin and Dunkel, Anja and Navrátilová, Hana and Mladenovic, Natasa and Odermatt, Alex. (2020) Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration. Cellular and Molecular Life Sciences, 77 (6). pp. 1153-1175. 2019Akram, Muhammad and Patt, Melanie and Kaserer, Teresa and Temml, Veronika and Waratchareeyakul, Watcharee and Kratschmar, Denise V. and Haupenthal, Joerg and Hartmann, Rolf W. and Odermatt, Alex and Schuster, Daniela. (2019) Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase. Journal of Steroid Biochemistry and Molecular Biology, 192. p. 105358. Beck, Katharina R. and Inderbinen, Silvia G. and Kanagaratnam, Sharavan and Kratschmar, Denise V. and Jetten, Anton M. and Yamaguchi, Hideaki and Odermatt, Alex. (2019) 11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ. Journal of Lipid Research, 60. pp. 1535-1546. Beck, Katharina R. and Kanagaratnam, Sharavan and Kratschmar, Denise V. and Birk, Julia and Yamaguchi, Hideaki and Sailer, Andreas W. and Seuwen, Klaus and Odermatt, Alex. (2019) Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2. The Journal of steroid biochemistry and molecular biology, 190. pp. 19-28. Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2019) ACE inhibitor use and risk of cataract: a case-control analysis. The British journal of ophthalmology, 103 (11). pp. 1561-1565. Boccard, Julien and Tonoli, David and Strajhar, Petra and Jeanneret, Fabienne and Odermatt, Alex and Rudaz, Serge. (2019) Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening. Talanta, 195. pp. 77-86. Bühler, Tim and Schmid, Yasmin and Liechti, Matthias E.. (2019) Verdacht auf K.o.-Mittel: Diagnostik in der Notfallstation und Praxis. Praxis, 108 (13). pp. 869-876. Canonica, Jérémie and Frateschi, Simona and Boscardin, Emilie and Ebering, Anna and Sergi, Chloé and Jäger, Yannick and Peyrollaz, Thibaud and Mérillat, Anne-Marie and Maillard, Marc and Klusonova, Petra and Odermatt, Alex and Koesters, Robert and Debonneville, Anne and Staub, Olivier and Verouti, Sophia N. and Hummler, Edith. (2019) Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl- Cotransporter NCC and Transiently Affects Sodium Handling. Frontiers in physiology, 10. p. 989. Crane, Erika A. and Heydenreuter, Wolfgang and Beck, Katharina R. and Strajhar, Petra and Vomacka, Jan and Smiesko, Martin and Mons, Elma and Barth, Lydia and Neuburger, Markus and Vedani, Angelo and Odermatt, Alex and Sieber, Stephan A. and Gademann, Karl. (2019) Profiling withanolide A for therapeutic targets in neurodegenerative diseases. Bioorganic & medicinal chemistry, 27 (12). pp. 2508-2520. Egli, Jerome and Schlothauer, Tilman and Spick, Christian and Seeber, Stefan and Singer, Thomas and Odermatt, Alex and Iglesias, Antonio. (2019) The Binding of Human IgG to Minipig FcγRs - Implications for Preclinical Assessment of Therapeutic Antibodies. Pharmaceutical research, 36 (3). p. 47. Egli, Jerome and Schmucki, Roland and Loos, Benjamin and Reichl, Stephan and Grabole, Nils and Roller, Andreas and Ebeling, Martin and Odermatt, Alex and Iglesias, Antonio. (2019) The genomic organization and expression pattern of the low-affinity Fc gamma receptors (FcγR) in the Göttingen minipig. Immunogenetics, 71 (2). pp. 123-136. Keppner, Anna and Maric, Darko and Sergi, Chloé and Ansermet, Camille and De Bellis, Damien and Kratschmar, Denise V. and Canonica, Jérémie and Klusonova, Petra and Fenton, Robert A. and Odermatt, Alex and Crambert, Gilles and Hoogewijs, David and Hummler, Edith. (2019) Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion. Scientific Reports, 9 (1). p. 19540. Kolaczynska, Karolina E. and Luethi, Dino and Trachsel, Daniel and Hoener, Marius C. and Liechti, Matthias E.. (2019) Receptor Interaction Profiles of 4-Alkoxy-Substituted 2,5-Dimethoxyphenethylamines and Related Amphetamines. Frontiers in Pharmacology, 10. p. 1423. Leuppi-Taegtmeyer, Anne and Duthaler, Urs and Hammann, Felix and Schmid, Yasmin and Dickenmann, Michael and Amico, Patricia and Jehle, Andreas W. and Kalbermatter, Stefan and Lenherr, Christoph and Meyer Zu Schwabedissen, Henriette E. and Haschke, Manuel and Liechti, Matthias E. and Krähenbühl, Stephan. (2019) Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions. Nephrology, Dialysis, Transplantation, 34 (4). pp. 692-702. Luethi, Dino and Kolaczynska, Karolina E. and Walter, Melanie and Suzuki, Masaki and Rice, Kenner C. and Blough, Bruce E. and Hoener, Marius C. and Baumann, Michael H. and Liechti, Matthias E.. (2019) Metabolites of the ring-substituted stimulants MDMA, methylone and MDPV differentially affect human monoaminergic systems. Journal of Psychopharmacology, 33 (7). pp. 831-841. Mayer, Felix P. and Cintulova, Daniela and Pittrich, Dorothea A. and Wimmer, Laurin and Luethi, Dino and Holy, Marion and Jaentsch, Kathrin and Tischberger, Sonja and Gmeiner, Guenter and Hoener, Marius C. and Liechti, Matthias E. and Mihovilovic, Marko D. and Sitte, Harald H.. (2019) Stereochemistry of phase-1 metabolites of mephedrone determines their effectiveness as releasers at the serotonin transporter. Neuropharmacology, 148. pp. 199-209. Müller, Felix and Brändle, Raphael and Liechti, Matthias E. and Borgwardt, Stefan. (2019) Neuroimaging of chronic MDMA ("ecstasy") effects: A meta-analysis. Neuroscience and biobehavioral reviews, 96. pp. 10-20. Patt, Melanie. Xenobiotics interfering with corticosteroid action : from adrenal steroid synthesis to peripheral receptor activity. 2019, Doctoral Thesis, University of Basel, Faculty of Science. Rickli, Anna and Hoener, Marius C. and Liechti, Matthias E.. (2019) Pharmacological profiles of compounds in preworkout supplements ("boosters"). European Journal of Pharmacology, 859. p. 172515. Sandström, Jenny and Kratschmar, Denise V. and Broyer, Alexandra and Poirot, Olivier and Marbet, Philippe and Chantong, Boonrat and Zufferey, Fanny and Dos Santos, Tania and Boccard, Julien and Chrast, Roman and Odermatt, Alex and Monnet-Tschudi, Florianne. (2019) In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice. Archives of toxicology, 93. pp. 1649-1664. Scholz, Irene and Schmid, Yasmin and Exadaktylos, Aristomenis K. and Haschke, Manuel and Liechti, Matthias E. and Liakoni, Evangelia. (2019) Emergency department presentations related to abuse of prescription and over-the-counter drugs in Switzerland: time trends, sex and age distribution. Swiss Medical Weekly, 149. w20056. Strajhar, Petra and Vizeli, Patrick and Patt, Melanie and Dolder, Patrick C. and Kratschmar, Denise V. and Liechti, Matthias E. and Odermatt, Alex. (2019) Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study. Journal of Steroid Biochemistry and Molecular Biology, 186. pp. 212-225. Thompson, George R. and Beck, Katharina R. and Patt, Melanie and Kratschmar, Denise V. and Odermatt, Alex. (2019) Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2. Journal of the Endocrine Society, 3 (7). pp. 1361-1366. Tosti, Nadia. TEAD4 promotes tumorigenesis via regulation of HSP70B expression in hepatocellular carcinoma. 2019, Doctoral Thesis, University of Basel, Faculty of Science. Tsachaki, Maria and Odermatt, Alex. (2019) Subcellular localization and membrane topology of 17β-hydroxysteroid dehydrogenases. Molecular and cellular endocrinology, 489. pp. 98-106. Vizeli, Patrick and Liechti, Matthias E.. (2019) No Influence of Dopamine System Gene Variations on Acute Effects of MDMA. Frontiers in Psychiatry, 10. p. 755. Vizeli, Patrick and Meyer Zu Schwabedissen, Henriette E. and Liechti, Matthias E.. (2019) Role of serotonin transporter and receptor gene variations in the acute effects of MDMA in healthy subjects. ACS chemical neuroscience, 10 (7). pp. 3120-3131. Wood, David M. and De La Rue, Luke and Hosin, Ali A. and Jurgens, Gesche and Liakoni, Evangelia and Heyerdahl, Fritdjof and Hovda, Knut Erik and Dines, Alison and Giraudon, Isabelle and Liechti, Matthias E. and Dargan, Paul I.. (2019) Poor Identification of Emergency Department Acute Recreational Drug Toxicity Presentations Using Routine Hospital Coding Systems: the Experience in Denmark, Switzerland and the UK. Journal of medical toxicology. pp. 1-9. 2018Appenzeller-Herzog, Christian and Riemer, Jan. (2018) Techniques to Monitor Disulfide Bond Formation and the Reduction Potential of Cysteine-Cystine Couples In vitro and In vivo. In: Oxidative Folding of Proteins: Basic Principles, Cellular Regulation and Engineering. Cambridge UK, pp. 34-51. Araya, Selene. Toward the identification of a function of the "orphan" enzyme DHRS7. 2018, Doctoral Thesis, University of Basel, Faculty of Science. Becker, Claudia and Schneider, Cornelia and Aballéa, Samuel and Bailey, Clare and Bourne, Rupert and Jick, Susan and Meier, Christoph. (2018) Cataract in patients with diabetes mellitus-incidence rates in the UK and risk factors. Eye (London, England), 32 (6). pp. 1028-1035. Boudon, Stephanie and Heidl, Marc and Vuorinen, Anna and Wandeler, Eliane and Campiche, Remo and Odermatt, Alex and Jackson, Eileen. (2018) Design, synthesis, and biological evaluation of novel selective peptide inhibitors of 11β-hydroxysteroid dehydrogenase 1. Bioorganic & medicinal chemistry, 26 (18). pp. 5128-5139. Boxler, Martina I. and Streun, Gabriel L. and Liechti, Matthias E. and Schmid, Yasmin and Kraemer, Thomas and Steuer, Andrea E.. (2018) Human Metabolome Changes after a Single Dose of 3,4-Methylenedioxymethamphetamine (MDMA) with Special Focus on Steroid Metabolism and Inflammation Processes. Journal of proteome research, 17 (8). pp. 2900-2907. Dolder, Patrick C. and Müller, Felix and Schmid, Yasmin and Borgwardt, Stefan J. and Liechti, Matthias E.. (2018) Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects. Psychopharmacology, 235 (2). pp. 467-479. Dolder, Patrick C. and Strajhar, Petra and Vizeli, Patrick and Odermatt, Alex and Liechti, Matthias E.. (2018) Acute effects of lisdexamfetamine and D-amphetamine on social cognition and cognitive performance in a placebo-controlled study in healthy subjects. Psychopharmacology, 235 (5). pp. 1389-1402. Egli, Jérôme. Identification and characterization of FcγRs in Göttingen minipigs – implications for preclinical assessment of therapeutic antibodies. 2018, Doctoral Thesis, University of Basel, Faculty of Science. Emmerich, Juliette and van Koppen, Chris J. and Burkhart, Jens L. and Engeli, Roger T. and Hu, Qingzhong and Odermatt, Alex and Hartmann, Rolf W.. (2018) Accelerated skin wound healing by selective 11β²-Hydroxylase (CYP11B1) inhibitors. European journal of medicinal chemistry, 143. pp. 591-597. Engeli, Roger T. and Fürstenberger, Cornelia and Kratschmar, Denise V. and Odermatt, Alex. (2018) Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis. Heliyon, 4 (2). e00527. Gruntz, Katharina and Bloechliger, Marlene and Becker, Claudia and Jick, Susan S. and Fuhr, Peter and Meier, Christoph R. and Rüegg, Stephan. (2018) Parkinson disease and the risk of epileptic seizures. Annals of Neurology, 83 (2). pp. 363-374. Liakoni, Evangelia and Yates, Christopher and Dines, Alison M. and Dargan, Paul I. and Heyerdahl, Fridtjof and Hovda, Knut Erik and Wood, David M. and Eyer, Florian and Liechti, Matthias E. and Euro-DEN Plus Research Group, . (2018) Acute recreational drug toxicity: Comparison of self-reports and results of immunoassay and additional analytical methods in a multicenter European case series. Medicine, 97 (5). e9784. Liao, Wan-Hui and Suendermann, Claudia and Steuer, Andrea Eva and Pacheco Lopez, Gustavo and Odermatt, Alex and Faresse, Nourdine and Henneberg, Maciej and Langhans, Wolfgang. (2018) Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity. JCI insight, 3 (14). e99015. Lister, Adam and Bourgeois, Soline and Imenez Silva, Pedro H. and Rubio-Aliaga, Isabel and Marbet, Philippe and Walsh, Joanne and Shelton, Luke M. and Keller, Bettina and Verrey, Francois and Devuyst, Olivier and Giesbertz, Pieter and Daniel, Hannelore and Goldring, Christopher E. and Copple, Ian M. and Wagner, Carsten A. and Odermatt, Alex. (2018) NRF2 regulates the glutamine transporter Slc38a3 (SNAT3) in kidney in response to metabolic acidosis. Scientific reports, 8 (1). p. 5629. Luethi, Dino and Kaeser, Philine J. and Brandt, Simon D. and Krähenbühl, Stephan and Hoener, Marius C. and Liechti, Matthias E.. (2018) Pharmacological profile of methylphenidate-based designer drugs. Neuropharmacology, 134 (Part A). pp. 133-140. Luethi, Dino and Kolaczynska, Karolina E. and Docci, Luca and Krähenbühl, Stephan and Hoener, Marius C. and Liechti, Matthias E.. (2018) Pharmacological profile of mephedrone analogs and related new psychoactive substances. Neuropharmacology, 134 (Part A). pp. 4-12. Luethi, Dino and Liechti, Matthias E.. (2018) Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoactive Stimulants and Psychedelics. International Journal of Neuropsychopharmacology, 21 (10). pp. 926-931. Maier, Julian and Mayer, Felix P. and Luethi, Dino and Holy, Marion and Jäntsch, Kathrin and Reither, Harald and Hirtler, Lena and Hoener, Marius C. and Liechti, Matthias E. and Pifl, Christian and Brandt, Simon D. and Sitte, Harald H.. (2018) The psychostimulant (±)-cis-4,4'-dimethylaminorex (4,4'-DMAR) interacts with human plasmalemmal and vesicular monoamine transporters. Neuropharmacology, 138. pp. 282-291. Marbet, Philippe. Implementation of primary cells for mechanistic investigations of inflammatory and metabolic diseases. 2018, Doctoral Thesis, University of Basel, Faculty of Science. Marbet, Philippe and Klusonova, Petra and Birk, Julia and Kratschmar, Denise V. and Odermatt, Alex. (2018) Absence of hexose-6-phosphate dehydrogenase results in reduced overall glucose consumption but does not prevent 11β-hydroxysteroid dehydrogenase-1-dependent glucocorticoid activation. The FEBS journal, 285 (21). pp. 3993-4004. Müller, Felix and Dolder, Patrick C. and Schmidt, André and Liechti, Matthias E. and Borgwardt, Stefan. (2018) Altered network hub connectivity after acute LSD administration. NeuroImage. Clinical, 18. pp. 694-701. Müller, Felix and Liechti, Matthias E. and Lang, Undine E. and Borgwardt, Stefan. (2018) Advances and challenges in neuroimaging studies on the effects of serotonergic hallucinogens: Contributions of the resting brain. Progress in brain research, 242. pp. 159-177. Prestigiacomo, Vincenzo. Investigation of the role of Nrf2 in hepatic stellate cells during liver fibrosis using in vitro models. 2018, Doctoral Thesis, University of Basel, Faculty of Science. Rickli, Anna and Liakoni, Evangelia and Hoener, Marius C. and Liechti, Matthias E.. (2018) Opioid-induced inhibition of the human 5-HT and noradrenaline transporters in vitro: link to clinical reports of serotonin syndrome. British Journal of Pharmacology, 175 (3). pp. 532-543. Schmid, Yasmin and Liechti, Matthias E.. (2018) Long-lasting subjective effects of LSD in normal subjects. Psychopharmacology, 235 (2). pp. 535-545. Schmidt, A. and Müller, F. and Lenz, C. and Dolder, P. C. and Schmid, Y. and Zanchi, D. and Lang, U. E. and Liechti, M. E. and Borgwardt, S.. (2018) Acute LSD effects on response inhibition neural networks. Psychological Medicine, 48 (9). pp. 1464-1473. Schmidt, André and Müller, Felix and Dolder, Patrick C. and Schmid, Yasmin and Zanchi, Davide and Egloff, Laura and Liechti, Matthias E. and Borgwardt, Stefan. (2018) Acute Effects of Methylphenidate, Modafinil, and MDMA on Negative Emotion Processing. The international journal of neuropsychopharmacology, 21 (4). pp. 345-354. Simmler, Linda D. and Liechti, Matthias E.. (2018) Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances. Handbook of experimental pharmacology. pp. 143-164. Tsachaki, Maria and Mladenovic, Natasa and Štambergová, Hana and Birk, Julia and Odermatt, Alex. (2018) Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balance. FASEB journal, 32 (5). pp. 2690-2705. Vizeli, Patrick and Liechti, Matthias E.. (2018) Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects. PloS one, 13 (6). e0199384. Vizeli, Patrick and Meyer Zu Schwabedissen, Henriette E. and Liechti, Matthias E.. (2018) No major role of norepinephrine transporter gene variations in the cardiostimulant effects of MDMA. European Journal of Clinical Pharmacology, 74 (3). pp. 275-283. 2017Aghagolzadeh, Parisa and Radpour, Ramin and Bachtler, Matthias and van Goor, Harry and Smith, Edward R. and Lister, Adam and Odermatt, Alex and Feelisch, Martin and Pasch, Andreas. (2017) Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation. Atherosclerosis, 265. pp. 78-86. Alesutan, Ioana and Voelkl, Jakob and Feger, Martina and Kratschmar, Denise V. and Castor, Tatsiana and Mia, Sobuj and Sacherer, Michael and Viereck, Robert and Borst, Oliver and Leibrock, Christina and Gawaz, Meinrad and Kuro-O, Makoto and Pilz, Stefan and Tomaschitz, Andreas and Odermatt, Alex and Pieske, Burkert and Wagner, Carsten A. and Lang, Florian. (2017) Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells. Scientific Reports, 7 (1). p. 2059. Araya, Selene and Kratschmar, Denise V. and Tsachaki, Maria and Stücheli, Simon and Beck, Katharina R. and Odermatt, Alex. (2017) DHRS7 (SDR34C1) - A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone? Journal of Steroid Biochemistry and Molecular Biology, 27. pp. 288-295. Beck, Katharina R. and Bächler, Murielle and Vuorinen, Anna and Wagner, Sandra and Akram, Muhammad and Griesser, Ulrich and Temml, Veronika and Klusonova, Petra and Yamaguchi, Hideaki and Schuster, Daniela and Odermatt, Alex. (2017) Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole. Biochemical pharmacology, 130. pp. 93-103. Beck, Katharina R. and Kaserer, Teresa and Schuster, Daniela and Odermatt, Alex. (2017) Virtual screening applications in short-chain dehydrogenase/reductase research. Journal of Steroid Biochemistry and Molecular Biology, 171. pp. 157-177. Beck, Katharina Richarda. Small molecule-protein interactions exemplified on short-chain dehydrogenases/reductases. 2017, Doctoral Thesis, University of Basel, Faculty of Science. Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2017) Selective Serotonin Reuptake Inhibitors and Cataract Risk: A Case-Control Analysis. Ophthalmology: Journal of The American Academy of Ophthalmology, 124 (11). pp. 1635-1639. Becker, Claudia and Jick, Susan S. and Meier, Christoph R. and Bodmer, Michael. (2017) Metformin and the risk of renal cell carcinoma: a case-control analysis. European Journal of Cancer Prevention , 26 (3). pp. 257-262. Ben Rhouma, Bochra and Kallabi, Fakhri and Mahfoudh, Nadia and Ben Mahmoud, Afif and Engeli, Roger T. and Kamoun, Hassen and Keskes, Leila and Odermatt, Alex and Belguith, Neila. (2017) Novel cases of Tunisian patients with mutations in the gene encoding 17β-hydroxysteroid dehydrogenase type 3 and a founder effect. Journal of Steroid Biochemistry and Molecular Biology, 165 (A). pp. 86-94. Bonifacio, Annalisa and Sanvee, Gerda M. and Brecht, Karin and Kratschmar, Denise V. and Odermatt, Alex and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91 (5). pp. 2223-2234. Boudon, Stéphanie M. and Vuorinen, Anna and Geotti-Bianchini, Piero and Wandeler, Eliane and Kratschmar, Denise V. and Heidl, Marc and Campiche, Remo and Jackson, Eileen and Odermatt, Alex. (2017) Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UV. PLoS ONE, 12 (2). e0171079. Dolder, Patrick C. and Strajhar, Petra and Vizeli, Patrick and Hammann, Felix and Odermatt, Alex and Liechti, Matthias E.. (2017) Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects. Frontiers in pharmacology, 8. p. 617. Engeli, Roger T. and Rohrer, Simona R. and Vuorinen, Anna and Herdlinger, Sonja and Kaserer, Teresa and Leugger, Susanne and Schuster, Daniela and Odermatt, Alex. (2017) Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases. International Journal of Molecular Sciences, 18 (9). pp. 1-13. Engeli, Roger T. and Tsachaki, Maria and Hassan, Heba A. and Sager, Christoph P. and Essawi, Mona L. and Gad, Yehia Z. and Kamel, Alaa K. and Mazen, Inas and Odermatt, Alex. (2017) Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients. The journal of sexual medicine, 14 (9). pp. 1165-1174. Engeli, Roger Thomas. Physiological and biochemical aspects of 17β-hydroxysteroid dehydrogenase type 2 and 3. 2017, Doctoral Thesis, University of Basel, Faculty of Science. Jiménez-Canino, Rubén and Lorenzo-Díaz, Fabián and Odermatt, Alex and Bailey, Matthew A. and Livingstone, Dawn E. W. and Jaisser, Frederic and Farman, Nicolette and Alvarez de la Rosa, Diego. (2017) 11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation. Endocrinology, 158 (11). pp. 4047-4063. Knöpfel, Thomas and Pastor-Arroyo, Eva M. and Schnitzbauer, Udo and Kratschmar, Denise V. and Odermatt, Alex and Pellegrini, Giovanni and Hernando, Nati and Wagner, Carsten A.. (2017) The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction. Scientific reports, 7 (1). p. 11018. Legeza, Balázs and Marcolongo, Paola and Gamberucci, Alessandra and Varga, Viola and Bánhegyi, Gábor and Benedetti, Angiolo and Odermatt, Alex. (2017) Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome. Nutrients, 9 (5). E426. Luethi, Dino and Trachsel, Daniel and Hoener, Marius C. and Liechti, Matthias E.. (2017) Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs). Neuropharmacology, 134. pp. 141-148. Morgan, Ruth A. and Beck, Katharina R. and Nixon, Mark and Homer, Natalie Z. M. and Crawford, Andrew A. and Melchers, Diana and Houtman, René and Meijer, Onno C. and Stomby, Andreas and Anderson, Anna J. and Upreti, Rita and Stimson, Roland H. and Olsson, Tommy and Michoel, Tom and Cohain, Ariella and Ruusalepp, Arno and Schadt, Eric E. and Björkegren, Johan L. M. and Andrew, Ruth and Kenyon, Christopher J. and Hadoke, Patrick W. F. and Odermatt, Alex and Keen, John A. and Walker, Brian R.. (2017) Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity. Scientific Reports, 7 (1). p. 10633. Randazzo, Giuseppe Marco and Tonoli, David and Strajhar, Petra and Xenarios, Ioannis and Odermatt, Alex and Boccard, Julien and Rudaz, Serge. (2017) Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study. Journal of Chromatography B, 1071. pp. 11-18. Strajhar, Petra. The effects of xenobiotics on steroidogenesis in human: "in vitro" and "in vivo" investigations. 2017, Doctoral Thesis, University of Basel, Faculty of Science. Strajhar, Petra and Tonoli, David and Jeanneret, Fabienne and Imhof, Raphaella M. and Malagnino, Vanessa and Patt, Melanie and Kratschmar, Denise V. and Boccard, Julien and Rudaz, Serge and Odermatt, Alex. (2017) Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids. Toxicology, 381. pp. 51-63. Tsachaki, Maria and Meyer, Arne and Weger, Benjamin and Kratschmar, Denise V. and Tokarz, Janina and Adamski, Jerzy and Belting, Heinz-Georg and Affolter, Markus and Dickmeis, Thomas and Odermatt, Alex. (2017) Absence of 11-keto reduction of cortisone and 11-ketotestosterone in the model organism zebrafish. Journal of Endocrinology, 232 (2). pp. 323-335. Vuorinen, Anna and Engeli, Roger T. and Leugger, Susanne and Bachmann, Fabio and Akram, Muhammad and Atanasov, Atanas G. and Waltenberger, Birgit and Temml, Veronika and Stuppner, Hermann and Krenn, Liselotte and Ateba, Sylvin B. and Njamen, Dieudonné and Davis, Rohan A. and Odermatt, Alex and Schuster, Daniela. (2017) Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2. Journal of Natural Products, 80 (4). pp. 965-974. Vuorinen, Anna and Engeli, Roger T. and Leugger, Susanne and Kreutz, Christoph R. and Schuster, Daniela and Odermatt, Alex and Matuszczak, Barbara. (2017) Phenylbenzenesulfonates and -sulfonamides as 17β-hydroxysteroid dehydrogenase type 2 inhibitors: Synthesis and SAR-analysis. Bioorganic & Medicinal Chemistry Letters, 27 (13). pp. 2982-2985. May 2016Canonica, Jérémie and Sergi, Chloé and Maillard, Marc and Klusonova, Petra and Odermatt, Alex and Koesters, Robert and Loffing-Cueni, Dominique and Loffing, Johannes and Rossier, Bernard and Frateschi, Simona and Hummler, Edith. (2016) Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype. Pflügers Archiv : European journal of physiology, 468 (5). pp. 895-908. Mani, Orlando and Nashev, Lyubomir G. and Livelo, Christopher and Baker, Michael E. and Odermatt, Alex. (2016) Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone. The Journal of steroid biochemistry and molecular biology, 159. pp. 31-40. April 2016Odermatt, Alex and Strajhar, Petra and Engeli, Roger T.. (2016) Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools. The Journal of steroid biochemistry and molecular biology, 158. pp. 9-21. Ramming, Thomas and Kanemura, Shingo and Okumura, Masaki and Inaba, Kenji and Appenzeller-Herzog, Christian. (2016) Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover. Redox biology, 7. pp. 14-20. March 2016Strajhar, Petra and Schmid, Y. and Liakoni, E. and Dolder, P. C. and Rentsch, K. M. and Kratschmar, Denise V. and Odermatt, Alex and Liechti, Matthias E.. (2016) Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects. Journal of Neuroendocrinology, 28 (3). p. 12374. February 2016Rizner, Tea Lanisnik and Sasano, Hironobu and Choi, Man Ho and Odermatt, Alex and Adamski, Jerzy. (2016) Recommendations for description and validation for antibodies for research use. The journal of steroid biochemistry and molecular biology, 156. pp. 40-42. January 2016Engeli, Roger T. and Rhouma, Bochra Ben and Sager, Christoph P. and Tsachaki, Maria and Birk, Julia and Fakhfakh, Faiza and Keskes, Leila and Belguith, Neila and Odermatt, Alex. (2016) Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development. The Journal of steroid biochemistry and molecular biology, 155. pp. 147-154. 2016Afonso, A. and Schmiedl, S. and Becker, C. and Tcherny-Lessenot, S. and Primatesta, P. and Plana, E. and Souverein, P. and Wang, Y. and Korevaar, J. C. and Hasford, J. and Reynolds, R. and de Groot, M. C. H. and Schlienger, R. and Klungel, O. and Rottenkolber, M.. (2016) A methodological comparison of two European primary care databases and replication in a US claims database: inhaled long-acting beta-2-agonists and the risk of acute myocardial infarction. European Journal of Clinical Pharmacology, 72 (9). pp. 1105-1116. Appenzeller-Herzog, Christian and Bánhegyi, Gabor and Bogeski, Ivan and Davies, Kelvin J. A. and Delaunay-Moisan, Agnès and Forman, Henry Jay and Görlach, Agnes and Kietzmann, Thomas and Laurindo, Francisco and Margittai, Eva and Meyer, Andreas J. and Riemer, Jan and Rützler, Michael and Simmen, Thomas and Sitia, Roberto and Toledano, Michel B. and Touw, Ivo P.. (2016) Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish. Free radical biology & medicine, 94. pp. 157-160. Appenzeller-Herzog, Christian and Simmen, Thomas. (2016) ER-luminal thiol/selenol-mediated regulation of Ca2+ signalling. Biochemical Society transactions, 44 (2). pp. 452-459. Beck, Katharina R. and Sommer, Tanja J. and Schuster, Daniela and Odermatt, Alex. (2016) Evaluation of tetrabromobisphenol A effects on human glucocorticoid and androgen receptors: A comparison of results from human- with yeast-based in vitro assays. Toxicology, 370. pp. 70-77. Calabrese, Diego. Use of laser capture microdissection to generate a translational map of gene expression patterns in the liver. 2016, Doctoral Thesis, University of Basel, Faculty of Science. Dubost, Valérie. Assessment of podocyte injury using two novel glomerular markers. 2016, Doctoral Thesis, University of Basel, Faculty of Science. Kanemura, Shingo and Okumura, Masaki and Yutani, Katsuhide and Ramming, Thomas and Hikima, Takaaki and Appenzeller-Herzog, Christian and Akiyama, Shuji and Inaba, Kenji. (2016) Human ER Oxidoreductin-1α (Ero1α) Undergoes Dual Regulation through Complementary Redox Interactions with Protein-Disulfide Isomerase. The Journal of biological chemistry, 291 (46). pp. 23952-23964. Uddin, Md Jamal and Groenwold, Rolf H. H. and de Boer, Anthonius and Afonso, Ana S. M. and Primatesta, Paola and Becker, Claudia and Belitser, Svetlana V. and Hoes, Arno W. and Roes, Kit C. B. and Klungel, Olaf H.. (2016) Evaluating different physician's prescribing preference based instrumental variables in two primary care databases: a study of inhaled long-acting beta2-agonist use and the risk of myocardial infarction. Pharmacoepidemiology and Drug Safety, 25 (Supplement 1). pp. 132-141. December 2015Kaserer, Teresa and Beck, Katharina and Akram, Muhamad and Odermatt, Alex and Schuster, Daniela. (2015) Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases. Molecules, 20 (12). pp. 22799-22832. Shelton, Luke M. and Lister, Adam and Walsh, Joanne and Jenkins, Rosalind E. and Wong, Michael H. L. and Rowe, Cliff and Ricci, Emanuele and Ressel, Lorenzo and Fang, Yongxiang and Demougin, Philippe and Vukojevic, Vanja and O'Neill, Paul M. and Goldring, Christopher E. and Kitteringham, Neil R. and Park, B. Kevin and Odermatt, Alex and Copple, Ian M.. (2015) Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. Kidney international, 88 (6). pp. 1261-1273. 1 November 2015Di Chiara, Marianna and Glaudemans, Bob and Loffing-Cueni, Dominique and Odermatt, Alex and Al-Hasani, Hadi and Devuyst, Olivier and Faresse, Nourdine and Loffing, Johannes. (2015) Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney. American journal of physiology. Gastrointestinal and liver physiology, 309 (9). F779-F790. November 2015Seibert, Julia K. and Quagliata, Luca and Quintavalle, Cristina and Hammond, Thomas G. and Terracciano, Luigi and Odermatt, Alex. (2015) A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer. Cancer medicine, 4 (11). pp. 1717-1729. 16 October 2015Becker, Claudia and Jick, Susan S. and Meier, Christoph R. and Bodmer, Michael. (2015) No evidence for a decreased risk of thyroid cancer in association with use of metformin or other antidiabetic drugs: a case-control study. BMC Cancer, 15. p. 719. July 2015Odermatt, Alex and Klusonova, Petra. (2015) 11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story. The journal of steroid biochemistry and molecular biology, 151. pp. 85-92. Tsachaki, Maria and Birk, Julia and Egert, Aurélie and Odermatt, Alex. (2015) Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions. Biochimica et biophysica acta. Molecular cell research, 1853 (7). pp. 1672-1682. June 2015Delaunay-Moisan, Agnès and Appenzeller-Herzog, Christian. (2015) The antioxidant machinery of the endoplasmic reticulum: Protection and signaling. Free radical biology & medicine, 83. pp. 341-351. Ramming, Thomas and Okumura, Masaki and Kanemura, Shingo and Baday, Sefer and Birk, Julia and Moes, Suzette and Spiess, Martin and Jenö, Paul and Bernèche, Simon and Inaba, Kenji and Appenzeller-Herzog, Christian. (2015) A PDI-catalyzed thiol-disulfide switch regulates the production of hydrogen peroxide by human Ero1. Free radical biology & medicine, 83. pp. 361-372. May 2015Tonoli, David and Fürstenberger, Cornelia and Boccard, Julien and Hochstrasser, Denis and Jeanneret, Fabienne and Odermatt, Alex and Rudaz, Serge. (2015) Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells. Chemical research in toxicology, 28 (5). pp. 955-966. April 2015Vuorinen, Anna and Seibert, Julia and Papageorgiou, Vassilios P. and Rollinger, Judith M. and Odermatt, Alex and Schuster, Daniela and Assimopoulou, Andreana N.. (2015) Pistacia lentiscus Oleoresin: Virtual Screening and Identification of Masticadienonic and Isomasticadienonic Acids as Inhibitors of 11β-Hydroxysteroid Dehydrogenase 1. Planta medica, 81 (6). pp. 525-532. February 2015Rottenkolber, Marietta and Voogd, Eef and van Dijk, Liset and Primatesta, Paola and Becker, Claudia and Schlienger, Raymond and de Groot, Mark C. H. and Alvarez, Yolanda and Durand, Julie and Slattery, Jim and Afonso, Ana and Requena, Gema and Gil, Miguel and Alvarez, Arturo and Hesse, Ulrik and Gerlach, Roman and Hasford, Joerg and Fischer, Rainald and Klungel, Olaf H. and Schmiedl, Sven. (2015) Time trends of period prevalence rates of patients with inhaled long-acting beta-2-agonists-containing prescriptions: a European comparative database study. PLoS ONE, 10 (2). e0117628. 2015Rottenkolber, M. and Voogd, E. and van Dijk, L. and Primatesta, P. and Becker, C. and de Groot, M. C. H. and Plana, E. and Alvarez, Y. and Durand, J. and Slattery, J. and Afonso, A. and Requena, G. and Huerta, C. and Alvarez, A. and de Abajo, F. and Tauscher, M. and Hasford, J. and Fischer, R. and Reynolds, R. and Schmiedl, S.. (2015) Seasonal changes in prescribing of long-acting beta-2-agonists-containing drugs. Respiratory Medicine, 109 (7). pp. 828-837. Seibert, Julia Katharina. Characterization of the 11β-hydroxysteroid dehydrogenase 1-related short-chain dehydrogenase/reductase DHRS7. 2015, Doctoral Thesis, University of Basel, Faculty of Science. Vuorinen, Anna and Odermatt, Alex and Schuster, Daniela. (2015) Reprint of "In silico methods in the discovery of endocrine disrupting chemicals". The Journal of steroid biochemistry and molecular biology, 153 (September 2015). pp. 93-101. 2014Becker, C. and Jick, S. S. and Meier, C. R. and Bodmer, M.. (2014) Metformin and the risk of head and neck cancer: a case-control analysis. Diabetes, Obesity and Metabolism, 16 (11). pp. 1148-1154. Blüthgen, Nancy. Effects of UV filters (benzophenones and octocrylene) and mifepristone on different life stages of zebrafish (Danio rerio). 2014, Doctoral Thesis, University of Basel, Faculty of Science. Blüthgen, Nancy and Meili, Nicole and Chew, Geraldine and Odermatt, Alex and Fent, Karl. (2014) Accumulation and effects of the UV-filter octocrylene in adult and embryonic zebrafish (Danio rerio). Science of the Total Environment, 476-477. pp. 207-217. Boudon, Stéphanie Marie and Morandi, Grégory and Prideaux, Brendan and Staab, Dieter and Junker, Ursula and Odermatt, Alex and Stoeckli, Markus and Bauer, Daniel. (2014) Evaluation of sparfloxacin distribution by mass spectrometry imaging in a phototoxicity model. Journal of the American Society for Mass Spectrometry, 25 (10). pp. 1803-1809. Boudon, Stéphanie Marie and Plappert-Helbig, Ulla and Odermatt, Alex and Bauer, Daniel. (2014) Characterization of vemurafenib phototoxicity in a mouse model. Review of Economic Dynamics, 137 (1). pp. 259-267. Chantong, Boonrat. Regulation of microglial cell function by corticosteroids and disruption by organotins. 2014, Doctoral Thesis, University of Basel, Faculty of Science. Chantong, Boonrat and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex. (2014) Dibutyltin promotes oxidative stress and increases inflammatory mediators in BV-2 microglia cells. Toxicology letters, Vol. 230, H. 2. pp. 177-187. Chantong, Boonrat and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex. (2014) Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive G i -proteins in murine BV-2 microglia cells. Journal of neuroinflammation, Vol. 11, H. 1. p. 190. Copple, Ian M. and Shelton, Luke M. and Walsh, Joanne and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex and Goldring, Christopher E. and Dinkova-Kostova, Albena T. and Honda, Tadashi and Park, B. Kevin. (2014) Chemical tuning enhances both potency toward nrf2 and in vitro therapeutic index of triterpenoids. Review of Economic Dynamics, 140 (2). pp. 462-469. Felser, Andrea and Lindinger, Peter W. and Schnell, Dominik and Kratschmar, Denise V. and Odermatt, Alex and Mies, Suzette and Jenö, Paul and Krähenbühl, Stephan. (2014) Hepatocellular toxicity of benzbromarone : Effects on mitochondrial function and structure. Toxicology, Vol. 324. pp. 136-146. Fürstenberger, Cornelia. Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes. 2014, Doctoral Thesis, University of Basel, Faculty of Science. Gai, Zhibo and Chu, Lei and Hiller, Christian and Arsenijevic, Denis and Penno, Carlos A. and Montani, Jean-Pierre and Odermatt, Alex and Kullak-Ublick, Gerd A.. (2014) Effect of chronic renal failure on the hepatic, intestinal, and renal expression of bile acid transporters. American Journal of Physiology - Renal Physiology, 306 (1). F130-137. Legeza, Balázs and Balázs, Zoltán and Odermatt, Alex. (2014) Fructose promotes the differentiation of 3T3-L1 adipocytes and accelerates lipid metabolism. FEBS letters, Vol. 588, H. 3. pp. 490-496. Penno, Carlos A. and Morgan, Stuart A. and Rose, Adam J. and Herzig, Stephan and Lavery, Gareth G. and Odermatt, Alex. (2014) 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. Molecular metabolism, Vol. 3, H. 5. pp. 554-564. Ramming, Thomas and Hansen, Henning Gram and Nagata, Kazuhiro and Ellgaard, Lars and Appenzeller-Herzog, Christian. (2014) GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum. Free radical biology & medicine, Vol. 70 , S. 106–116. Seibert, Julia and Hysek, Cédric M. and Penno, Carlos A. and Schmid, Yasmin and Kratschmar, Denise V. and Liechti, Matthias E. and Odermatt, Alex. (2014) Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects. Neuroendocrinology, 100 (1). pp. 17-25. Vuorinen, Anna and Engeli, Roger and Meyer, Arne and Bachmann, Fabio and Griesser, Ulrich J. and Schuster, Daniela and Odermatt, Alex. (2014) Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors. Journal of medicinal chemistry, Vol. 57, H. 14. pp. 5995-6007. Vuorinen, Anna and Nashev, Lyubomir G. and Odermatt, Alex and Rollinger, Judith M. and Schuster, Daniela. (2014) Pharmacophore model refinement for 11β-hydroxysteroid dehydrogenase inhibitors: Search for modulators of intracellular glucocorticoid concentrations. Molecular Informatics, 33. pp. 15-25. 2013Appenzeller-Herzog, Christian and Birk, Julia. (2013) Erratum: Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise. Frontiers in genetics, Vol. 4, art. 255 , 1 S.. Becker, Claudia and Jick, Susan S. and Meier, Christoph R. and Bodmer, Michael. (2013) Metformin and the risk of endometrial cancer: a case-control analysis. Gynecologic Oncology, 129 (3). pp. 565-569. Becker, Claudia and Meier, Christoph R. and Jick, Susan S. and Bodmer, Michael. (2013) Case-control analysis on metformin and cancer of the esophagus. Cancer Causes & Control, 24 (10). pp. 1763-1770. Birk, Julia and Meyer, Mariangela and Aller, Isabel and Hansen, Henning G. and Odermatt, Alex and Dick, Tobias P. and Meyer, Andreas J. and Appenzeller-Herzog, Christian. (2013) Endoplasmic reticulum : reduced and oxidized glutathione revisited. Journal of Cell Science, 126 (7). pp. 1604-1617. Birk, Julia and Meyer, Mariangela and Aller, Isabel and Hansen, Henning G. and Odermatt, Alex and Dick, Tobias P. and Meyer, Andreas J. and Appenzeller-Herzog, Christian. (2013) Endoplasmic reticulum: reduced and oxidized glutathione revisited. Journal of Cell Science, 126. pp. 1604-1617. Birk, Julia and Ramming, Thomas and Odermatt, Alex and Appenzeller-Herzog, Christian. (2013) Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise. Frontiers in genetics, Vol. 4, art. 108 , 10 S.. p. 108. Blüthgen, Nancy and Sumpter, John P. and Odermatt, Alex and Fent, Karl. (2013) Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 2. Gene expression analysis and in vitro activity. Aquatic Toxicology, 144-145. pp. 96-104. Boudon, Stéphanie. Characterization of phototoxicity reactions in human and animal skin models. 2013, Doctoral Thesis, University of Basel, Faculty of Science. Hofer, Sandra and Kratschmar, Denise V. and Schernthanner, Brigitte and Vuorinen, Anna and Schuster, Daniela and Odermatt, Alex and Easmon, Johnny. (2013) Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11β-hydroxysteroid dehydrogenase 1 inhibitors. Bioorganic and Medicinal Chemistry Letters, 23 (19). pp. 5397-5400. Legeza, Balazs. Generation and utilization of NADPH in the endoplasmic reticulum : novel insight into the role of luminal NADPH in pathophysiological processes. 2013, Doctoral Thesis, University of Basel, Faculty of Science. Legeza, Balázs and Balázs, Zoltán and Nashev, Lyubomir G. and Odermatt, Alex. (2013) The microsomal enzyme 17β-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase. Endocrinology, Vol. 154, H. 1. pp. 205-213. Leunig, M. and Jüni, P. and Werlen, S. and Limacher, A. and Nüesch, E. and Pfirrmann, C. W. and Trelle, S. and Odermatt, A. and Hofstetter, W. and Ganz, R. and Reichenbach, S.. (2013) Prevalence of cam and pincer-type deformities on hip MRI in an asymptomatic young Swiss female population: a cross-sectional study. Osteoarthritis and Cartilage , 21 (4). pp. 544-550. Marchais-Oberwinkler, Sandrine and Xu, Kuiying and Wetzel, Marie and Perspicace, Enrico and Negri, Matthias and Meyer, Arne and Odermatt, Alex and Möller, Gabriele and Adamski, Jerzy and Hartmann, Rolf W.. (2013) Structural Optimization of 2,5-Thiophene Amides as Highly Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors for the Treatment of Osteoporosis. Journal of Medicinal Chemistry, Vol. 56, H. 1. pp. 167-181. Meyer, Arne. The role of the endoplasmic reticulum in the metabolism of "xenobiotica". 2013, Doctoral Thesis, University of Basel, Faculty of Science. Meyer, Arne and Vuorinen, Anna and Zielinska, Agnieszka E. and Da Cunha, Thierry and Strajhar, Petra and Lavery, Gareth G. and Schuster, Daniela and Odermatt, Alex. (2013) Carbonyl reduction of triadimefon by human and rodent 11β-hydroxysteroid dehydrogenase 1. Biochemical pharmacology, Vol. 85, H. 9. pp. 1370-1378. Meyer, Arne and Vuorinen, Anna and Zielinska, Agnieszka E. and Strajhar, Petra and Lavery, Gareth G. and Schuster, Daniela and Odermatt, Alex. (2013) Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1. Drug metabolism and disposition, Vol. 41, H. 9. pp. 1671-1678. Montero, Davide and Tachibana, Christine and Rahr Winther, Jakob and Appenzeller-Herzog, Christian. (2013) Intracellular glutathione pools are heterogeneously concentrated. Redox biology, Vol. 1, H. 1. pp. 508-513. Nashev, Lyubomir G. and Atanasov, Atanas G. and Baker, Michael E. and Odermatt, Alex. (2013) Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals. International journal of cell biology, Vol. 2013 , art. 769536. Pandya, Keyur and Dietrich, David and Seibert, Julia and Vederas, John C. and Odermatt, Alex. (2013) Synthesis of sterically encumbered 11β-aminoprogesterone derivatives and evaluation as 11β-hydroxysteroid dehydrogenase inhibitors and mineralocorticoid receptor antagonists. Bioorganic & medicinal chemistry letters, Vol. 21, H. 21. pp. 6274-6281. Penno, C. A. and Arsenijevic, D: Da Cunha and Kullak-Ublick, G. A. and Montani, J.-P. and Odermatt, A.. (2013) Quantification of multiple bile acids in uninephrectomized rats using ultra-performance liquid chromatography-tandem mass spectrometry. Analytical Methods, 5. pp. 1155-1164. Penno, Carlos A. and Morgan, Stuart A. and Vuorinen, Anna and Schuster, Daniela and Lavery, Gareth G. and Odermatt, Alex. (2013) Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid. Journal of Lipid Research, 54 (10). pp. 2874-2883. Penno, Carlos Alberto. The role of 11β-hydroxysteroid dehydrogenase type 1 in bile acid homeostasis. 2013, Doctoral Thesis, University of Basel, Faculty of Science. Ramming, Thomas and Appenzeller-Herzog, Christian. (2013) Destroy and exploit: catalyzed removal of hydroperoxides from the endoplasmic reticulum. International journal of cell biology, Vol. 2013 , 180906. Sorensen, Mads V. and Grossmann, Solveig and Roesinger, Marian and Gresko, Nikolay and Todkar, Abhijeet P. and Barmettler, Gery and Ziegler, Urs and Odermatt, Alex and Loffing-Cueni, Dominique and Loffing, Johannes. (2013) Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice. Kidney International, 83 (5). pp. 811-824. Vuorinen, Anna and Odermatt, Alex and Schuster, Daniela. (2013) In silico methods in the discovery of endocrine disrupting chemicals. Journal of Steroid Biochemistry and Molecular Biology, 137. pp. 18-26. Wright, Jordan and Birk, Julia and Haataja, Leena and Liu, Ming and Ramming, Thomas and Weiss, Michael A. and Appenzeller-Herzog, Christian and Arvan, Peter. (2013) Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress. Journal of biological chemistry, 288 (43). pp. 31010-31018. 2012Appenzeller-Herzog, Christian. (2012) Updates on "Endoplasmic Reticulum Redox". Antioxidants & redox signaling, Vol. 16, No. 8. pp. 760-762. Bodmer, Michael and Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2012) Metformin does not alter the risk of lung cancer : a case-control analysis. Lung Cancer, 78 (2). pp. 133-137. Bodmer, Michael and Becker, Claudia and Meier, Christian and Jick, Susan S. and Meier, Christoph R.. (2012) Use of antidiabetic agents and the risk of pancreatic cancer : a case-control analysis. The American journal of gastroenterology, 107 (4). pp. 620-626. Bodmer, Michael and Becker, Claudia and Meier, Christian and Jick, Susan S. and Meier, Christoph R.. (2012) Use of metformin is not associated with a decreased risk of colorectal cancer: a case-control analysis. Cancer epidemiology biomarkers & prevention, 21 (2). pp. 280-286. Chantong, Boonrat and Kratschmar, Denise V. and Nashev, Lyubomir G. and Balazs, Zoltan and Odermatt, Alex. (2012) Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells. Journal of neuroinflammation, Vol. 9. p. 260. Fürstenberger, Cornelia and Vuorinen, Anna and Da Cunha, Thierry and Kratschmar, Denise V. and Saugy, Martial and Schuster, Daniela and Odermatt, Alex. (2012) The anabolic androgenic steroid fluoxymesterone inhibits 11β-hydroxysteroid dehydrogenase 2-dependent glucocorticoid inactivation. Toxicological sciences, Vol. 126, H. 2. pp. 353-361. Hansen, Henning Gram and Schmidt, Jonas Damgård and Søltoft, Cecilie Lützen and Ramming, Thomas and Geertz-Hansen, Henrik Marcus and Christensen, Brian and Sørensen, Esben Skipper and Juncker, Agnieszka Sierakowska and Appenzeller-Herzog, Christian and Ellgaard, Lars. (2012) Hyperactivity of the ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response. Journal of biological chemistry, Vol. 287, H. 47. pp. 39513-39523. Kratschmar, Denise V. and Calabrese, Diego and Walsh, Jo and Lister, Adam and Birk, Julia and Appenzeller-Herzog, Christian and Moulin, Pierre and Goldring, Chris E. and Odermatt, Alex. (2012) Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells. PLoS ONE, 7 (5). e36774. Meyer, Arne and Strajhar, Petra and Murer, Céline and Da Cunha, Thierry and Odermatt, Alex. (2012) Species-specific differences in the inhibition of human and zebrafish 11β-hydroxysteroid dehydrogenase 2 by thiram and organotins. Toxicology, Vol. 301, H. 1-3. pp. 72-78. Nashev, Lyubomir G. and Vuorinen, Anna and Praxmarer, Lukas and Chantong, Boonrat and Cereghetti, Diego and Winiger, Rahel and Schuster, Daniela and Odermatt, Alex. (2012) Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action. PLoS ONE, Vol. 7, H. 10 , e46958. Odermatt, Alex and Kratschmar, Denise V.. (2012) Tissue-specific modulation of mineralocorticoid receptor function by 11β-hydroxysteroid dehydrogenases : an overview. Molecular and cellular endocrinology, Vol. 350, H. 2. pp. 168-186. Ramming, Thomas and Appenzeller-Herzog, Christian. (2012) The physiological functions of mammalian endoplasmic oxidoreductin 1: on disulfides and more. Antioxidants & redox signaling, Vol. 16, No. 10. pp. 1109-1118. Vacchi-Suzzi, Caterina. MicroRNAs regulatory networks in cardiotoxicity. 2012, Doctoral Thesis, University of Basel, Faculty of Science. Veyrat-Durebex, Christelle and Deblon, Nicolas and Caillon, Aurélie and Andrew, Ruth and Altirriba, Jordi and Odermatt, Alex and Rohner-Jeanrenaud, Françoise. (2012) Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue. PLoS ONE, Vol. 7, H. 3 , e34002. 2011Appenzeller-Herzog, Christian. (2011) Glutathione- and non-glutathione-based oxidant control in the endoplasmic reticulum. Journal of cell science, Vol. 124, H. 6. pp. 847-855. Becker, C. and Brobert, G. P. and Johansson, S. and Jick, S. S. and Meier, C. R.. (2011) Risk of incident depression in patients with Parkinson disease in the UK. European Journal of Neurology, 18 (3). pp. 448-453. Becker, C. and Jick, S. S. and Meier, C. R.. (2011) NSAID use and risk of Parkinson disease : a population-based case-control study. European Journal of Neurology, 18 (11). pp. 1336-1342. Blumberg, Bruce and Iguchi, Taisen and Odermatt, Alex. (2011) Endocrine disrupting chemicals. The journal of steroid biochemistry and molecular biology, Vol. 127, H. 1/2. pp. 1-3. Bodmer, Michael and Becker, Claudia and Meier, Christian and Jick, Susan S. and Meier, Christoph R.. (2011) Use of metformin and the risk of ovarian cancer: a case-control analysis. Gynecologic oncology, 123 (2). pp. 200-204. Gaware, Rawindra and Khunt, Rupesh and Czollner, Laszlo and Stanetty, Christian and Da Cunha, Thierry and Kratschmar, Denise V. and Odermatt, Alex and Kosma, Paul and Jordis, Ulrich and Classen-Houben, Dirk. (2011) Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors. Bioorganic & medicinal chemistry, Vol. 19, H. 6. pp. 1866-1880. Kratschmar, Denise V. and Vuorinen, Anna and Da Cunha, Thierry and Wolber, Gerhard and Classen-Houben, Dirk and Doblhoff, Otto and Schuster, Daniela and Odermatt, Alex. (2011) Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11?-hydroxysteroid dehydrogenase type 2. The journal of steroid biochemistry and molecular biology, Vol. 125, H. 1-2. pp. 129-142. Odermatt, Alex. (2011) The Western-style diet : a major risk factor for impaired kidney function and chronic kidney disease. American journal of physiology. Renal Physiology, Vol. 301, H. 5 , F919-931. Odermatt, Alex and Da Cunha, Thierry and Penno, Carlos A. and Chandsawangbhuwana, Charlie and Reichert, Christian and Wolf, Armin and Dong, Min and Baker, Michael E.. (2011) Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11?-hydroxysteroid dehydrogenase 1. The Biochemical Journal, Vol. 436, H. 3. pp. 621-629. Reichenbach, Stephan and Leunig, Michael and Werlen, Stefan and Nüesch, Eveline and Pfirrmann, Christian W. and Bonel, Harald and Odermatt, Alex and Hofstetter, Willy and Ganz, Reinhold and Jüni, Peter. (2011) Association between cam-type deformities and magnetic resonance imaging-detected structural hip damage : a cross-sectional study in young men. Arthritis and rheumatism, Vol. 63, H. 12. pp. 4023-4030. Riemer, Jan and Hansen, Henning Gram and Appenzeller-Herzog, Christian and Johansson, Linda and Ellgaard, Lars. (2011) Identification of the PDI-family member ERp90 as an interaction partner of ERFAD. PLoS ONE, 6 (2). e17037. Schuster, Daniela and Kowalik, Dorota and Kirchmair, Johannes and Laggner, Christian and Markt, Patrick and Aebischer-Gumy, Christel and Ströhle, Fabian and Möller, Gabriele and Wolber, Gerhard and Wilckens, Thomas and Langer, Thierry and Odermatt, Alex and Adamski, Jerzy. (2011) Identification of chemically diverse, novel inhibitors of 17?-hydroxysteroid dehydrogenase type 3 and 5 by pharmacophore-based virtual screening. The journal of steroid biochemistry and molecular biology, Vol. 125, H. 1-2. pp. 148-161. 2010Appenzeller-Herzog, Christian and Riemer, Jan and Zito, Ester and Chin, King-Tung and Ron, David and Spiess, Martin and Ellgaard, Lars. (2010) Disulphide production by Ero1alpha-PDI relay is rapid and effectively regulated. The EMBO journal, Vol. 29, H. 19. pp. 3318-3329. Becker, Claudia and Brobert, Gunnar P. and Johansson, Saga and Jick, Susan S. and Meier, Christoph R.. (2010) Cancer risk in association with Parkinson disease : a population-based study. Parkinsonism & related disorders, 16 (3). pp. 186-190. Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2010) Risk of stroke in patients with idiopathic Parkinson disease. Parkinsonism & related disorders, 16 (1). pp. 31-35. Beseda, Igor and Czollner, Laszlo and Shah, Priti S. and Khunt, Rupesh and Gaware, Rawindra and Kosma, Paul and Stanetty, Christian and Del Ruiz-Ruiz, Maria Carmen and Amer, Hassan and Mereiter, Kurt and Da Cunha, Thierry and Odermatt, Alex and Classen-Houben, Dirk and Jordis, Ulrich. (2010) Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases. Bioorganic & medicinal chemistry, Vol. 18, H. 1. pp. 433-454. Nashev, Lyubomir G. and Schuster, Daniela and Laggner, Christian and Sodha, Seloni and Langer, Thierry and Wolber, Gerhard and Odermatt, Alex. (2010) The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3 : virtual screening as a strategy to identify potential endocrine disrupting chemicals. Biochemical Pharmacology, Vol. 79, Issue 8. pp. 1189-1199. Odermatt, Alex and Nashev, Lyubomir G.. (2010) The glucocorticoid-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations. The journal of steroid biochemistry and molecular biology, Vol. 119, H. 1-2. pp. 1-13. Reichenbach, Stephan and Jüni, Peter and Werlen, Stefan and Nüesch, Eveline and Pfirrmann, Christian W. and Trelle, Sven and Odermatt, Alex and Hofstetter, Willy and Ganz, Reinhold and Leunig, Michael. (2010) Prevalence of cam-type deformity on hip magnetic resonance imaging in young males : a cross-sectional study. Arthritis care & research, Vol. 62, H. 9. pp. 1319-1327. Rollinger, Judith M. and Kratschmar, Denise V. and Schuster, Daniela and Pfisterer, Petra H. and Gumy, Christel and Aubry, Evelyne M. and Brandstötter, Sarah and Stuppner, Hermann and Wolber, Gerhard and Odermatt, Alex. (2010) 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches. Bioorganic & medicinal chemistry, Vol. 18, H. 4. pp. 1507-1515. Senesi, Silvia and Legeza, Balázs and Balázs, Zoltán and Csala, Miklós and Marcolongo, Paola and Kereszturi, Eva and Szelényi, Péter and Egger, Christine and Fulceri, Rosella and Mandl, József and Giunti, Roberta and Odermatt, Alex and Bánhegyi, Gábor and Benedetti, Angelo. (2010) Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum : possible implication in the metabolic syndrome. Endocrinology, Vol. 151, H. 10. pp. 4830-4839. Stanetty, Christian and Czollner, Laszlo and Koller, Iris and Shah, Priti and Gaware, Rawindra and Cunha, Thierry Da and Odermatt, Alex and Jordis, Ulrich and Kosma, Paul and Classen-Houben, Dirk. (2010) Synthesis of novel 3-amino and 29-hydroxamic acid derivatives of glycyrrhetinic acid as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors. Bioorganic & medicinal chemistry, Vol. 18, H. 21. pp. 7522-7541. 2009Aubry, E. M. and Odermatt, A.. (2009) Retinoic acid reduces glucocorticoid sensitivity in C2C12 myotubes by decreasing 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor activities. Endocrinology, 150 (6). pp. 2700-2708. Balazs, Z. and Nashev, L. G. and Chandsawangbhuwana, C. and Baker, M. E. and Odermatt, A.. (2009) Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1. Molecular and cellular endocrinology, Vol. 301, H. 1-2. pp. 117-122. Classen-Houben, D. and Schuster, D. and Da Cunha, T. and Odermatt, A. and Wolber, G. and Jordis, U. and Kueenburg, B.. (2009) Selective inhibition of 11beta-hydroxysteroid dehydrogenase 1 by 18alpha-glycyrrhetinic acid but not 18beta-glycyrrhetinic acid. The journal of steroid biochemistry and molecular biology, Vol. 113, H. 3-5. pp. 248-252. Dzyakanchuk, A. A. and Balazs, Z. and Nashev, L. G. and Amrein, K. E. and Odermatt, A.. (2009) 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose. Molecular and cellular endocrinology, Vol. 301, H. 1-2. pp. 137-141. Gumy, C. and Thurnbichler, C. and Aubry, E. M. and Balazs, Z. and Pfisterer, P. and Baumgartner, L. and Stuppner, H. and Odermatt, A. and Rollinger, J. M.. (2009) Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines. Fitoterapia, Vol. 80, no.3. pp. 200-205. Odermatt, A.. (2009) Diazepane-acetamide derivatives as selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors. Expert opinion on therapeutic patents, Vol. 19, H. 10. pp. 1477-1483. Odermatt, A. and Atanasov, A. G.. (2009) Mineralocorticoid receptors : Emerging complexity and functional diversity. Steroids, Vol. 74, H. 2. pp. 163-171. Riemer, Jan and Appenzeller-Herzog, Christian and Johansson, Linda and Bodenmiller, Bernd and Hartmann-Petersen, Rasmus and Ellgaard, Lars. (2009) A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, H. 35. pp. 14831-14836. 2008Appenzeller-Herzog, Christian and Ellgaard, Lars. (2008) In vivo reduction-oxidation state of protein disulfide isomerase: the two active sites independently occur in the reduced and oxidized forms. Antioxidants and Redox Signaling, 10 (1). pp. 55-64. Appenzeller-Herzog, Christian and Ellgaard, Lars. (2008) The human PDI family: versatility packed into a single fold. Biochimica et Biophysica Acta, 1783 (4). pp. 535-548. Appenzeller-Herzog, Christian and Riemer, Jan and Christensen, Brian and Sørensen, Esben S. and Ellgaard, Lars. (2008) A novel disulphide switch mechanism in Ero1alpha balances ER oxidation in human cells. The EMBO Journal, 27 (22). pp. 2977-2987. Atanasov, Atanas G. and Nashev, Lyubomir G. and Gelman, Laurent and Legeza, Balazs and Sack, Ragna and Portmann, Reto and Odermatt, Alex. (2008) Direct protein-protein interaction of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen. Biochimica et biophysica acta. Molecular cell research, Vol. 1783, Issue 8. pp. 1536-1543. Balazs, Z. and Schweizer, R. A. and Frey, F. J. and Rohner-Jeanrenaud, F. and Odermatt, A.. (2008) DHEA induces 11beta-HSD2 by acting on CCAAT/enhancer-binding proteins. Journal of the American Society of Nephrology, Vol. 19, H. 1. pp. 92-101. Becker, C. and Brobert, G. P. and Almqvist, P. M. and Johansson, S. and Jick, S. S. and Meier, C. R.. (2008) Migraine incidence, comorbidity and health resource utilization in the UK. Studies in modern thermodynamics, 3. pp. 57-64. Becker, Claudia and Brobert, Gunnar P. and Almqvist, Per M. and Johansson, Saga and Jick, Susan S. and Meier, Christoph R.. (2008) The risk of newly diagnosed asthma in migraineurs with or without previous triptan prescriptions. Headache, 48 (4). pp. 606-610. Becker, Claudia and Brobert, Gunnar P. and Johansson, Saga and Jick, Susan S. and Meier, Christoph R.. (2008) Diabetes in patients with idiopathic Parkinson's disease. Diabetes Care, 31 (9). pp. 1808-1812. Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2008) Use of antihypertensives and the risk of Parkinson disease. Neurology, 70 (16 Pt. 2). pp. 1438-1444. Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2008) Use of statins and the risk of Parkinson's disease: a retrospective case-control study in the UK. Drug safety, 31 (5). pp. 399-407. 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