Items where Author is "Hall , M. N."

Yes

Venkatesh, A. and Ma, S. and Le, Y. Z. and Hall, M. N. and Rüegg, M. A. and Punzo, C.. (2015) Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. Journal of Clinical Investigation, 125 (4). pp. 1446-1458.

Carr, T. D. and Feehan, R. P. and Hall, M. N. and Rüegg, M. A. and Shantz, L. M.. (2015) Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. Carcinogenesis, 36 (4). pp. 487-497.

Oliveira, A. P. and Dimopoulos, S. and Busetto, A. G. and Christen, S. and Dechant, R. and Falter, L. and Haghir, C. M. and Jozefczuk, S. and Ludwig, C. and Rudroff, F. and Schulz, J. C. and González, A. and Soulard, A. and Stracka, D. and Aebersold, R. and Buhmann, J. M. and Hall, M. N. and Peter, M. and Sauer, U. and Stelling, J.. (2015) Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome. Molecular systems biology, Vol. 11, H. 4. p. 802.

Ma, S. and Venkatesh, A. and Langellotto, F. and Le, Y. Z. and Hall, M. N. and Rüegg, M. A. and Punzo, C.. (2015) Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival. Experimental Eye Research, 135. pp. 1-13.

González, A. and Shimobayashi, M. and Eisenberg, T. and Merle, D. A. and Pendl, T. and Hall, M. N. and Moustafa, T.. (2015) TORC1 Promotes Phosphorylation of Ribosomal Protein S6 via the AGC Kinase Ypk3 in Saccharomyces cerevisiae. PLoS ONE, Vol. 10, H. 3 , e0120250.

Faller, W. J. and Jackson, T. J. and Knight, J. R. P. and Ridgway, R. A. and Jamieson, T. and Karim, S. A. and Jones, C. and Radulescu, S. and Huels, D. J. and Myant, K. B. and Dudek, K. M. and Casey, H. A. and Scopelliti, A. and Cordero, J. B. and Vidal, M. and Pende, M. and Ryazanov, A. G. and Sonenberg, N. and Meyuhas, O. and Hall, M. N. and Bushell, M. and Willis, A. E. and Sansom, O. J.. (2015) mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature, 517 (7535). pp. 497-500.

Lebrun-Julien, F. and Bachmann, L. and Norrmén, C. and Trötzmüller, M. and Köfeler, H. and Rüegg, M. A. and Hall, M. N. and Suter, U.. (2014) Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination. Journal of Neuroscience, 34 (25). pp. 8432-8448.

Siamer, S. and Guillas, I. and Shimobayashi, M. and Kunz, C. and Hall, M. N. and Barny, M. A.. (2014) Expression of the bacterial type III effector DspA/E in Saccharomyces cerevisiae downregulates the sphingolipid biosynthetic pathway leading to growth-arrest. Journal of Biological Chemistry, 289 (26). pp. 18466-18477.

Cornu, M. and Oppliger, W. and Albert, V. and Robitaille, A. M. and Trapani, F. and Quagliata, L. and Fuhrer, T. and Sauer, U. and Terracciano, L. and Hall, M. N.. (2014) Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21. Proceedings of the National Academy of Sciences of the United States of America, 111 (32). pp. 11592-11599.

Umemura, A. and Park, E. J. and Taniguchi, K. and Lee, J. H. and Shalapour, S. and Valasek, M. A. and Aghajan, M. and Nakagawa, H. and Seki, E. and Hall, M. N. and Karin, M.. (2014) Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell metabolism, Vol. 20, H. 1. pp. 133-144.

Shimobayashi, M. and Hall, M. N.. (2014) Making new contacts : the mTOR network in metabolism and signalling crosstalk. Nature reviews. Molecular cell biology, Vol. 15, H. 3. pp. 155-162.

de Cabo, R. and Carmona-Gutierrez, D. and Bernier, M. and Hall, M. N. and Madeo, F.. (2014) The Search for Antiaging Interventions : From Elixirs to Fasting Regimens. Cell, 157 (7). pp. 1515-1526.

Chen, J. and Tu, X. and Esen, E. and Joeng, K. S. and Lin, C. and Arbeit, J. M. and Rüegg, M. A. and Hall, M. N. and Ma, L. and Long, F.. (2014) WNT7B promotes bone formation in part through mTORC1. PLoS Genetics, 10 (1). e1004145.

Albert, V. and Hall, M. N.. (2014) mTOR signaling in cellular and organismal energetics. Current Opinion in Cell Biology, Vol. 33. pp. 55-66.

Norrmén, C. and Figlia, G. and Lebrun-Julien, F. and Pereira, J. A. and Trötzmüller, M. and Köfeler, H. C. and Rantanen, V. and Wessig, C. and van Deijk, A. F. and Smit, A. B. and Verheijen, M. G. and Rüegg, M. A. and Hall, M. N. and Suter, U.. (2014) mTORC1 Controls PNS Myelination along the mTORC1-RXRγ-SREBP-Lipid Biosynthesis Axis in Schwann Cells. Cell Reports , 9 (2). pp. 646-660.

Grahammer, F. and Haenisch, N. and Steinhardt, F. and Sander, L. and Roerden, M. and Arnold, F. and Cordts, T. and Wanner, N. and Reichardt, W. and Kerjaschki, D. and Ruegg, M. A. and Hall, M. N. and Moulin, P. and Busch, H. and Boerries, M. and Walz, G. and Artunc, F. and Huber, T. B.. (2014) mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress. Proceedings of the National Academy of Sciences of the United States of America, 111 (27). E2817-E2826.

Benjamin, D. and Hall, M. N.. (2014) mTORC1: Turning Off Is Just as Important as Turning On. Cell, 156 (4). pp. 627-628.

Wyder Peters, L. and Molle, K. D. and Thiemeyer, A. and Knopf, A. and Goxe, M. and Guerry, P. and Brodbeck, D. and Colombi, M. and Hall, M. N. and Moroni, C. and Regenass, U.. (2013) An Isogenic Cell Panel Identifies Compounds That Inhibit Proliferation of mTOR-Pathway Addicted Cells by Different Mechanisms. Journal of Biomolecular Screening, 19 (1). pp. 131-144.

Shortt, J. and Martin, B. P. and Newbold, A. and Hannan, K. M. and Devlin, J. R. and Baker, A. J. and Ralli, R. and Cullinane, C. and Schmitt, C. A. and Reimann, M. and Hall, M. N. and Wall, M. and Hannan, R. D. and Pearson, R. B. and McArthur, G. A. and Johnstone, R. W.. (2013) Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas. Blood, Vol. 121, H. 15. pp. 2964-2974.

Thedieck, K. and Holzwarth, B. and Prentzell, M. T. and Boehlke, C. and Kläsener, K. and Ruf, S. and Sonntag, A. G. and Maerz, L. and Grellscheid, S. N. and Kremmer, E. and Nitschke, R. and Kuehn, E. W. and Jonker, J. W. and Groen, A. K. and Reth, M. and Hall, M. N. and Baumeister, R.. (2013) Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells. Cell, 154 (4). pp. 859-874.

Hall, M. N.. (2013) On mTOR nomenclature. Biochemical Society Transactions, 41 (4). pp. 8817-8888.

Blazek, M. and Betz, C. and Reth, M. and Hall, M. N. and Zengerle, R. and Meier, M.. (2013) Proximity Ligation Assay for High Content Profiling of Cell Signaling Pathways on a Microfluidic Chip. Molecular & cellular proteomics, Vol. 12. pp. 3898-3907.

Bhattacharya, I. and Drägert, K. and Albert, V. and Contassot, E. and Damjanovic, M. and Hagiwara, A. and Zimmerli, L. and Humar, R. and Hall, M. N. and Battegay, E. J. and Haas, E.. (2013) Rictor in Perivascular Adipose Tissue Controls Vascular Function by Regulating Inflammatory Molecule Expression. Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, H. 9. pp. 2105-2111.

Benjamin, D. and Hall, M. N.. (2013) TSC on the peroxisome controls mTORC1. Nature Cell Biology, Vol. 15, H. 10. pp. 1135-1136.

Saldivia, M. and Barquilla, A. and Bart, J. M. and Diaz-González, R. and Hall, M. N. and Navarro, M.. (2013) Target of rapamycin (TOR) kinase in Trypanosoma brucei : an extended family. Biochemical Society Transactions, 41 (4). pp. 934-938.

Betz, C. and Hall, M. N.. (2013) Where is mTOR and what is it doing there? Journal of cell biology, Vol. 203, H. 4. pp. 563-574.

Betz, C. and Stracka, D. and Prescianotto-Baschong, C. and Frieden, M. and Demaurex, N. and Hall, M. N.. (2013) mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology. Proceedings of the National Academy of Sciences of the United States of America, 110 (31). pp. 12526-12534.

Durán, R. V. and Oppliger, W. and Robitaille, A. M. and Heiserich, L. and Skendaj, R. and Gottlieb, E. and Hall, M. N.. (2012) Glutaminolysis activates Rag-mTORC1 signaling. Molecular Cell, 47 (3). pp. 349-358.

Durán, R. V. and Mackenzie, E. D. and Boulahbel, H. and Frezza, C. and Heiserich, L. and Tardito, S. and Bussolati, O. and Rocha, S. and Hall, M. N. and Gottlieb, E.. (2012) HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Oncogene, 32 (38). pp. 4549-4556.

Durán, R. V. and Hall, M. N.. (2012) Leucyl-tRNA synthetase : double duty in amino acid sensing. Cell Research, 22 (8). pp. 1207-1209.

Cardon, C. M. and Beck, T. and Hall, M. N. and Rutter, J.. (2012) PAS kinase promotes cell survival and growth through activation of Rho1. Science Signaling, 5 (209). ra9.

Robitaille, A. M. and Hall, M. N.. (2012) Ramping up mitosis : an AMPKα2-regulated signaling network promotes mitotic progression. Molecular Cell, 45 (1). pp. 8-9.

Durán, R. V. and Hall, M. N.. (2012) Regulation of TOR by small GTPases. EMBO Reports, 13 (2). pp. 121-128.

Liu, Q. and Ren, T. and Fresques, T. and Oppliger, W. and Niles, B. J. and Hur, W. and Sabatini, D. M. and Hall, M. N. and Powers, T. and Gray, N. S.. (2012) Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. ACS Chemical Biology, 7 (6). pp. 982-987.

Barquilla, A. and Saldivia, M. and Diaz, R. and Bart, J. -M. and Vidal, I. and Calvo, E. and Hall, M. N. and Navarro, M.. (2012) Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America, 109 (36). pp. 14399-14404.

Chan, J. C. and Hannan, K. M. and Riddell, K. and Ng, P. Y. and Peck, A. and Lee, R. S. and Hung, S. and Astle, M. V. and Bywater, M. and Wall, M. and Poortinga, G. and Jastrzbeski, K. and Sheppard, K. E. and Hemmings, B. A. and Hall, M. N. and Johnstone, R. W. and McArthur, G. A. and Hannan, R. D. and Pearson, R. B.. (2011) AKT is a critical regulator of rRNA synthesis and cooperates with c-MYC to control ribosome biogenesis in cancer. Science Signaling, 4 (188). ra56.

Zinzalla, V. and Stracka, D. and Oppliger, W. and Hall, M. N.. (2011) Activation of mTORC2 by Association with the Ribosome. Cell, 144 (5). pp. 757-768.

Shende, P. and Plaisance, I. and Morandi, C. and Pellieux, C. and Berthonneche, C. and Zorzato, F. and Krishnan, J. and Lerch, R. and Hall, M. N. and Ruegg, M. A. and Pedrazzini, T. and Brink, M.. (2011) Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. Circulation, 123 (10). pp. 1073-1082.

Colombi, M. and Molle, K. D. and Benjamin, D. and Rattenbacher-Kiser, K. and Schaefer, C. and Betz, C. and Thiemeyer, A. and Regenass, U. and Hall, M. N. and Moroni, C.. (2011) Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction. Oncogene, 30 (13). pp. 1551-1565.

Hall, M. N.. (2011) Growth grows up COCB themed issue on cell division, growth, and death. Current Opinion in Cell Biology, 23 (6). pp. 705-706.

Godel, M. and Hartleben, B. and Herbach, N. and Liu, S. and Zschiedrich, S. and Lu, S. and Debreczeni-Mor, A. and Lindenmeyer, M. T. and Rastaldi, M. -P. and Hartleben, G. and Wiech, T. and Fornoni, A. and Nelson, R. G. and Kretzler, M. and Wanke, R. and Pavenstadt, H. and Kerjaschki, D. and Cohen, C. D. and Hall, M. N. and Ruegg, M. A. and Inoki, K. and Walz, G. and Huber, T. B.. (2011) Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. Journal of Clinical Investigation, 121 (6). pp. 2197-2209.

Loewith, R. and Hall, M. N.. (2011) Target of Rapamycin (TOR) in nutrient signaling and growth control. Genetics, 189 (4). pp. 1177-1201.

Hall, M. N.. (2011) The history and perspectives of TOR research. Jikken Igaku (Experimental Medicine), Vol. 29. pp. 862-864.

Dazert, E. and Hall, M. N.. (2011) mTOR signaling in disease. Current Opinion in Cell Biology, 23 (6). pp. 744-755.

Inoki, K. and Mori, H. and Wang, J. and Suzuki, T. and Hong, S. and Yoshida, S. and Blattner, S. M. and Ikenoue, T. and Ruegg, M. A. and Hall, M. N. and Kwiatkowski, D. J. and Rastaldi, M. P. and Huber, T. B. and Kretzler, M. and Holzman, L. B. and Wiggins, R. C. and Guan, K. -L.. (2011) mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. Journal of Clinical Investigation, 121 (6). pp. 2181-2196.

Soulard, A. and Cremonesi, A. and Moes, S. and Schutz, F. and Jeno, P. and Hall, M. N.. (2010) The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates. Molecular Biology of the Cell, 21 (19). pp. 3475-3486.

Thedieck, K. and Hall, M. N.. (2010) Translational control by amino acids and energy. In: Handbook of cell signaling, Vol. 3. San Diego, California, pp. 2285-2293.

Cornu, M. and Hall, M. N.. (2010) mTORC1 and mTORC2 in energy homeostasis. In: Structure, function and regulation of TOR complexes from yeasts to mammals, Part B. Amsterdam, pp. 263-278.

Michels, A. A. and Robitaille, A. M. and Buczynski-Ruchonnet, D. and Hodroj, W. and Reina, J. H. and Hall, M. N. and Hernandez, N.. (2010) mTORC1 directly phosphorylates and regulates human MAF1. Molecular and cellular biology, Vol. 30, H. 15. pp. 3749-3757.

Sturgill, T. W. and Hall, M. N.. (2009) Activating Mutations in TOR Are in Similar Structures As Oncogenic Mutations in PI3KCalpha. ACS chemical biology, Vol. 4, no. 12. pp. 999-1015.

Cohen, A. and Hall, M. N.. (2009) An amino acid shuffle activates mTORC1. Cell, 136 (3). pp. 399-400.

Cybulski, N. and Hall, M. N.. (2009) TOR complex 2 : a signaling pathway of its own. Trends in Biochemical Sciences, 34 (12). pp. 620-627.

Soulard, A. and Cohen, A. and Hall, M. N.. (2009) TOR signaling in invertebrates. Current Opinion in Cell Biology, 21 (6). pp. 825-836.

Patursky-Polischuk, I. and Stolovich-Rain, M. and Hausner-Hanochi, M. and Kasir, J. and Cybulski, N. and Avruch, J. and Ruegg, M. A. and Hall, M. N. and Meyuhas, O.. (2009) The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner. Molecular and cellular biology, Vol. 29, H. 3. pp. 640-649.

Polak, P. and Hall, M. N.. (2009) mTOR and the control of whole body metabolism. Current Opinion in Cell Biology, 21 (2). pp. 209-218.

Cybulski, N. and Polak, P. and Auwerx, J. and Ruegg, M. A. and Hall, M. N.. (2009) mTOR complex 2 in adipose tissue negatively controls whole-body growth. Proceedings of the National Academy of Sciences of the United States of America, 106 (24). pp. 9902-9907.

Polak, P. and Cybulski, N. and Feige, J. N. and Auwerx, J. and Ruegg, M. A. and Hall, M. N.. (2008) Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration. Cell Metabolism, Vol. 8, H. 5. pp. 399-410.

Gander, S. and Bonenfant, D. and Altermatt, P. and Martin, D. E. and Hauri, S. and Moes, S. and Hall, M. N. and Jenoe, P.. (2008) Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase. Rapid communications in mass spectrometry, Vol. 22, H. 23. pp. 3743-3753.

Jiang, H. and Schiffer, E. and Song, Z. and Wang, J. and Zurbig, P. and Thedieck, K. and Moes, S. and Bantel, H. and Saal, N. and Jantos, J. and Brecht, M. and Jeno, P. and Hall, M. N. and Hager, K. and Manns, M. P. and Hecker, H. and Ganser, A. and Dohner, K. and Bartke, A. and Meissner, C. and Mischak, H. and Ju, Z. and Rudolph, K. L.. (2008) Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proceedings of the National Academy of Sciences of the United States of America, 105 (32). pp. 11299-11304.

Zinzalla, V. and Hall, M. N.. (2008) Signal transduction : linking nutrients to growth. Nature, 454. pp. 287-288.

Bentzinger, C. F. and Romanino, K. and Cloetta, D. and Lin, S. and Mascarenhas, J. B. and Oliveri, F. and Xia, J. and Casanova, E. and Costa, C. F. and Brink, M. and Zorzato, F. and Hall, M. N. and Ruegg, M. A.. (2008) Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metabolism, 8 (5). pp. 411-424.

Bentzinger, C. F. and Romanino, K. and Cloëtta, D. and Lin, S. and Mascarenhas, J. B. and Oliveri, F. and Xia, J. and Casanova, E. and Costa, C. F. and Brink, M. and Zorzato, F. and Hall, M. N. and Rüegg, M. A.. (2008) Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metabolism, 8 (5). pp. 411-424.

Sturgill, T. W. and Cohen, A. and Diefenbacher, M. and Trautwein, M. and Martin, D. E. and Hall, M. N.. (2008) TOR1 and TOR2 have distinct locations in live cells. Eukaryotic Cell, Vol. 7, H. 10. pp. 1819-1830.

Robitaille, A. M. and Hall, M. N.. (2008) mTor. UCSD Nature Molecular Pages, 2008, A000094.

Sturgill, T. W. and Hall, M. N.. (2007) Holding back TOR advances mitosis. Nature Cell Biology, Vol. 9, H. 11. pp. 1221-1222.

Thedieck, K. and Polak, P. and Kim, M. L. and Molle, K. D. and Cohen, A. and Jeno, P. and Arrieumerlou, C. and Hall, M. N.. (2007) PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS ONE, Vol. 2, H. 11 , e1217.

Urban, J. and Soulard, A. and Huber, A. and Lippman, S. and Mukhopadhyay, D. and Deloche, O. and Wanke, V. and Anrather, D. and Ammerer, G. and Riezman, H. and Broach, J. R. and De Virgilio, C. and Hall, M. N. and Loewith, R.. (2007) Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Molecular cell, Vol. 26, H. 5. pp. 663-674.

Soulard, A. and Hall, M. N.. (2007) SnapShot : mTOR signaling. Cell, 129 (2). p. 434.

Mulet, J. M. and Martin, D. E. and Loewith, R. and Hall, M. N.. (2006) Mutual antagonism of target of rapamycin and calcineurin signaling. Journal of Biological Chemistry, 281 (44). pp. 33000-33007.

Martin, D. E. and Powers, T. and Hall, M. N.. (2006) Regulation of ribosome biogenesis : where is TOR? Cell Metabolism, Vol. 4, H. 4. pp. 259-260.

Wullschleger, S. and Loewith, R. and Hall, M. N.. (2006) TOR signaling in growth and metabolism. Cell, 124 (3). pp. 471-484.

Polak, P. and Hall, M. N.. (2006) mTORC2 Caught in a SINful Akt. Developmental cell, Vol. 11, H. 4. pp. 433-434.

Wullschleger, S. and Loewith, R. and Oppliger, W. and Hall, M. N.. (2005) Molecular organization of target of rapamycin complex 2. Journal of Biological Chemistry, 280 (35). pp. 30697-30704.

Martin, D. E. and Hall, M. N.. (2005) The expanding TOR signaling network. Current Opinion in Cell Biology, 17 (2). pp. 158-166.

Dames, S. A. and Mulet, J. M. and Rathgeb-Szabo, K. and Hall, M. N. and Grzesiek, S.. (2005) The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. Journal of Biological Chemistry, 280 (21). pp. 20558-20564.

Kamada, Y. and Fujioka, Y. and Suzuki, N. N. and Inagaki, F. and Wullschleger, S. and Loewith, R. and Hall, M. N. and Ohsumi, Y.. (2005) Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Molecular and Cellular Biology, Vol. 25, H. 16. pp. 7239-7248.

Schmelzle, T. and Beck, T. and Martin, D. E. and Hall, M. N.. (2004) Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast. Molecular and cellular biology, Vol. 24, H. 1. pp. 338-351.

Jacinto, E. and Loewith, R. and Schmidt, A. and Lin, S. and Ruegg, M. A. and Hall, A. and Hall, M. N.. (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nature Cell Biology, Vol. 6, H. 11. pp. 1122-1128.

Crespo, J. L. and Helliwell, S. B. and Wiederkehr, C. and Demougin, P. and Fowler, B. and Primig, M. and Hall, M. N.. (2004) NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae. Journal of Biological Chemistry, 279 (36). pp. 37512-37517.

Morales-Johansson, H. and Jenoe, P. and Cooke, F. T. and Hall, M. N.. (2004) Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4. Journal of Biological Chemistry, 279 (38). pp. 39604-39610.

Martin, D. E. and Demougin, P. and Hall, M. N. and Bellis, M.. (2004) Rank difference analysis of microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data. BMC bioinformatics, Vol. 5 , 148.

Lorberg, A. and Hall, M. N.. (2004) TOR - the first 10 years. Current Topics in Microbiology and Immunology, 279. pp. 1-18.

Martin, D. E. and Soulard, A. and Hall, M. N.. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell, 119 (7). pp. 969-979.

Loewith, R. and Hall, M. N.. (2004) TOR signaling in yeast : temporal and spatial control of cell growth. In: Cell growth. New York, pp. 139-166.

Schmelzle, T. and Crespo, J. L. and Hall, M. N.. (2004) Translational control by amino acids and energy. In: Handbook of cell signaling, Vol. 3. San Diego, California, pp. 299-303.

Burri, L. and Vascotto, K. and Fredersdorf, S. and Tiedt, R. and Hall, M. N. and Lithgow, T.. (2004) Zim17 : a novel zinc finger protein essential for protein import into mitochondria. Journal of Biological Chemistry, 279 (48). pp. 50243-50249.

Bonenfant, D. and Schmelzle, T. and Jacinto, E. and Crespo, J. L. and Mini, T. and Hall, M. N. and Jenoe, P.. (2003) Quantitation of changes in protein phosphorylation : a simple method based on stable isotope labeling and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America, 100 (3). pp. 880-885.

Jacinto, E. and Hall, M. N.. (2003) Tor signalling in bugs, brain and brawn. Nature reviews. Molecular cell biology, Vol. 4, H. 2. pp. 117-126.

Desrivieres, S. and Cooke, F. T. and Morales-Johansson, H. and Parker, P. J. and Hall, M. N.. (2002) Calmodulin controls organization of the actin cytoskeleton via regulation of phosphatidylinositol (4,5)-bisphosphate synthesis in Saccharomyces cerevisiae. Biochemical Journal, 366 (3). pp. 945-951.

Crespo, J. L. and Hall, M. N.. (2002) Elucidating TOR signaling and rapamycin action : lessons from Saccharomyces cerevisiae. Microbiology and molecular biology reviews, Vol. 66, H. 4. pp. 579-591.

Schmidt, A. and Schmelzle, T. and Hall, M. N.. (2002) The RHO1-GAPs SAC7, BEM2 and BAG7 control distinct RHO1 functions in Saccharomyces cerevisiae. Molecular Microbiology, 45 (5). pp. 1433-1441.

Crespo, J. L. and Powers, T. and Fowler, B. and Hall, M. N.. (2002) The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine. Proceedings of the National Academy of Sciences of the United States of America, 99 (10). pp. 6784-6789.

Loewith, R. and Jacinto, E. and Wullschleger, S. and Lorberg, A. and Crespo, J. L. and Bonenfant, D. and Oppliger, W. and Jenoe, P. and Hall, M. N.. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Molecular cell, Vol. 10, H. 3. pp. 457-468.

Schmelzle, T. and Helliwell, S. B. and Hall, M. N.. (2002) Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast. Molecular and Cellular Biology, Vol. 22, H. 5. pp. 1329-1339.

Beck, T. and Delley, P. A. and Hall, M. N.. (2001) Control of the actin cytoskeleton by extracellular signals. In: Molecular interactions of actin, Vol. 1: Actin structure and actin-binding proteins. Heidelberg, pp. 231-262.

Friant, S. and Lombardi, R. and Schmelzle, T. and Hall, M. N. and Riezman, H.. (2001) Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast. The EMBO Journal, 20 (23). pp. 6783-6792.

Jacinto, E. and Guo, B. and Arndt, K. T. and Schmelzle, T. and Hall, M. N.. (2001) TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Molecular cell, Vol. 8, H. 5. pp. 1017-1026.

Hall, M. N. and Sabatini, D. M.. (2001) TOR and Control of Cell Growth. In: Cahiers de la Fondation des Treilles, 13. Paris, pp. 62-82.

Crespo, J. L. and Daicho, K. and Ushimaru, T. and Hall, M. N.. (2001) The GATA transcription factors GLN3 and GAT1 link TOR to salt stress in Saccharomyces cerevisiae. Journal of Biological Chemistry, 276 (37). pp. 34441-34444.

Brachat, A. and Liebundguth, N. and Rebischung, C. and Lemire, S. and Scharer, F. and Hoepfner, D. and Demchyshyn, V. and Howald, I. and Dusterhoft, A. and Mostl, D. and Pohlmann, R. and Kotter, P. and Hall, M. N. and Wach, A. and Philippsen, P.. (2000) Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames. Yeast, 16 (3). pp. 241-253.

Cosentino, G. P. and Schmelzle, T. and Haghighat, A. and Helliwell, S. B. and Hall, M. N. and Sonenberg, N.. (2000) Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Molecular and Cellular Biology, Vol. 20, H. 13. pp. 4604-4613.

Kunz, J. and Loeschmann, A. and Deuter-Reinhard, M. and Hall, M. N.. (2000) FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast. Molecular Microbiology, 37 (6). pp. 1480-1493.

Kunz, J. and Schneider, U. and Howald, I. and Schmidt, A. and Hall, M. N.. (2000) HEAT repeats mediate plasma membrane localization of Tor2p in yeast. Journal of Biological Chemistry, 275 (47). pp. 37011-37020.

Schmelzle, T. and Hall, M. N.. (2000) TOR, a central controller of cell growth. Cell, 103 (2). pp. 253-262.

Danaie, P. and Altmann, M. and Hall, M. N. and Trachsel, H. and Helliwell, S. B.. (1999) CLN3 expression is sufficient to restore G1-to-S-phase progression in Saccharomyces cerevisiae mutants defective in translation initiation factor eIF4E. Biochemical Journal, 340 (1). pp. 135-141.

Delley, P. A. and Hall, M. N.. (1999) Cell wall stress depolarizes cell growth via hyperactivation of RHO1. The Journal of cell biology, Vol. 147, H. 1. pp. 163-174.

Inagaki, M. and Schmelzle, T. and Yamaguchi, K. and Irie, K. and Hall, M. N. and Matsumoto, K.. (1999) PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast. Molecular and Cellular Biology, Vol. 19, H. 12. pp. 8344-8352.

Beck, T. and Schmidt, A. and Hall, M. N.. (1999) Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast. The Journal of cell biology, Vol. 146, H. 6. pp. 1227-1238.

Beck, T. and Hall, M. N.. (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature, 402. pp. 689-692.

Bickle, M. and Delley, P. A. and Schmidt, A. and Hall, M. N.. (1998) Cell wall integrity modulates RHO1 activity via the exchange factor ROM2. The EMBO Journal, 17 (8). pp. 2235-2245.

Desrivieres, S. and Cooke, F. T. and Parker, P. J. and Hall, M. N.. (1998) MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae. Journal of Biological Chemistry, 273 (25). pp. 15787-15793.

Schmidt, A. and Hall, M. N.. (1998) Signaling to the actin cytoskeleton. Annual review of cell and developmental biology, Vol. 14. pp. 305-338.

Helliwell, S. B. and Howald, I. and Barbet, N. and Hall, M. N.. (1998) TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. Genetics, 148 (1). pp. 99-112.

Helliwell, S. B. and Schmidt, A. and Ohya, Y. and Hall, M. N.. (1998) The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Current Biology, 8 (22). pp. 1211-1214.

Schmidt, A. and Beck, T. and Koller, A. and Kunz, J. and Hall, M. N.. (1998) The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. The EMBO Journal, 17 (23). pp. 6924-6931.

Cooke, F. T. and Dove, S. K. and McEwen, R. K. and Painter, G. and Holmes, A. B. and Hall, M. N. and Michell, R. H. and Parker, P. J.. (1998) The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Current Biology, 8 (22). pp. 1219-1222.

Thomas, G. and Hall, M. N.. (1997) TOR signalling and control of cell growth. Current Opinion in Cell Biology, 9 (6). pp. 782-787.

Schmidt, A. and Bickle, M. and Beck, T. and Hall, M. N.. (1997) The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell, 88 (4). pp. 531-542.

Hall, M. N.. (1996) Drug discovery : rational serendipity. Trends in Biochemical Sciences, 21 (8). pp. 322-323.

Beretta, L. and Gingras, A. C. and Svitkin, Y. V. and Hall, M. N. and Sonenberg, N.. (1996) Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. The EMBO Journal, 15 (3). pp. 658-664.

Koller, A. and Heitman, J. and Hall, M. N.. (1996) Regional bivalent-univalent pairing versus trivalent pairing of a trisomic chromosome in Saccharomyces cerevisiae. Genetics, 144 (3). pp. 957-966.

Barbet, N. C. and Schneider, U. and Helliwell, S. B. and Stansfield, I. and Tuite, M. F. and Hall, M. N.. (1996) TOR controls translation initiation and early G1 progression in yeast. Molecular Biology of the Cell, 7 (1). pp. 25-42.

Schmidt, A. and Kunz, J. and Hall, M. N.. (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 13780-13785.

Hall, M. N.. (1996) The TOR signalling pathway and growth control in yeast. Biochemical Society Transactions, 24 (1). pp. 234-239.

Hall, M. N.. (1996) Yeast cloning book cloning. Trends in Cell Biology, 6 (2). p. 80.

Hall, M. N.. (1994) Cytosplasm-to-nucleus signaling in yeast: use of immunosuppressive drugs as probes. In: Trafic des Protéines chez les Microorganismes. Paris, pp. 55-57.

Garcia-Bustos, J. F. and Marini, F. and Stevenson, I. and Frei, C. and Hall, M. N.. (1994) PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus. The EMBO Journal, 13 (10). pp. 2352-2361.

Helliwell, S. B. and Wagner, P. and Kunz, J. and Deuter-Reinhard, M. and Henriquez, R. and Hall, M. N.. (1994) TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Molecular Biology of the Cell, 5 (1). pp. 105-118.

Hottiger, T. and De Virgilio, C. and Hall, M. N. and Boller, T. and Wiemken, A.. (1994) The role of trehalose synthesis for the acquisition of thermotolerance in yeast : II. Physiological concentrations of trehalose increase the thermal stability of proteins in vitro. European Journal of Biochemistry, 219 (1-2). pp. 187-193.

Schmidt, A. and Hall, M. N. and Koller, A.. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Molecular and Cellular Biology, Vol. 14, H. 10. pp. 6597-6606.

Kunz, J. and Hall, M. N.. (1993) Cyclosporin A, FK506 and rapamycin : more than just immunosuppression. Trends in Biochemical Sciences, 18 (9). pp. 334-348.

Heitman, J. and Koller, A. and Cardenas, M. E. and Hall, M. N.. (1993) Identification of immunosuppressive drug targets in yeast. Methods, Vol. 5, no. 2. pp. 176-187.

Wagner, P. and Hall, M. N.. (1993) Nuclear protein transport is functionally conserved between yeast and higher eukaryotes. FEBS Letters, 321 (2-3). pp. 261-266.

Kunz, J. and Henriquez, R. and Schneider, U. and Deuter-Reinhard, M. and Movva, N. R. and Hall, M. N.. (1993) Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell, 73 (3). pp. 585-596.

Heitman, J. and Koller, A. and Kunz, J. and Henriquez, R. and Schmidt, A. and Movva, N. R. and Hall, M. N.. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Molecular and cellular biology, Vol. 13, H. 8. pp. 5010-5019.

Davis, E. S. and Becker, A. and Heitman, J. and Hall, M. N. and Brennan, M. B.. (1992) A yeast cyclophilin gene essential for lactate metabolism at high temperature. Proceedings of the National Academy of Sciences of the United States of America, 89 (23). pp. 11169-11173.

Heitman, J. and Movva, N. R. and Hall, M. N.. (1992) Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. The New Biologist, Vol. 4, no. 5. pp. 448-460.

Tinland, B. and Koukolíková-Nicola, Z. and Hall, M. N. and Hohn, B.. (1992) The T-DNA-linked VirD2 protein contains two distinct functional nuclear localization signals. Proceedings of the National Academy of Sciences of the United States of America, 89 (16). pp. 7442-7446.

Heitman, J. and Movva, N. R. and Hiestand, P. C. and Hall, M. N.. (1991) FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 88 (5). pp. 1948-1952.

Tinland, B. and Hall, M. N. and Hohn, B.. (1991) Mechanism of T-DNA transfer. In: Proceedings of the 5th International Symposium on the molecular genetics of plant-microbe interactions, Interlaken, Switzerland, September 9-14, 1990. Dordrecht, pp. 79-84.

Garcia-Bustos, J. F. and Wagner, P. and Hall, M. N.. (1991) Nuclear import substrates compete for a limited number of binding sites : evidence for different classes of yeast nuclear import receptors. Journal of Biological Chemistry, 266 (33). pp. 22303-22306.

Garcia-Bustos, J. and Heitman, J. and Hall, M. N.. (1991) Nuclear protein localization. Biochimica et Biophysica Acta, 1071 (1). pp. 83-101.

Heitman, J. and Movva, N. R. and Hall, M. N.. (1991) Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science, 253 (5022). pp. 905-909.

Garcia-Bustos, J. F. and Wagner, P. and Hall, M. N.. (1991) Yeast cell-free nuclear protein import requires ATP hydrolysis. Experimental Cell Research, 192 (1). pp. 213-219.

Wagner, P. and Kunz, J. and Koller, A. and Hall, M. N.. (1990) Active transport of proteins into the nucleus. FEBS Letters, 275 (1-2). pp. 1-5.

Hall, M. N. and Craik, C. and Hiraoka, Y.. (1990) Homeodomain of yeast repressor alpha 2 contains a nuclear localization signal. Proceedings of the National Academy of Sciences of the United States of America, 87 (18). pp. 6954-6958.

Hall, M. N. and Fried, S. R.. (1988) Is nuclear protein localization receptor-mediated? In: Molecular Biology of Intracellular Protein Sorting and Organelle Assembly. New York, pp. 187-192.

Silver, P. A. and Hall, M. N.. (1988) Transport of proteins into the nucleus. In: Protein transfer and organelle biogenesis. San Diego, Calif., pp. 749-769.

Hall, M. N. and Johnson, A. D.. (1987) Homeo domain of the yeast repressor alpha 2 is a sequence-specific DNA-binding domain but is not sufficient for repression. Science, 237 (4818). pp. 1007-1012.

Benson, S. A. and Hall, M. N. and Rasmussen, B. A.. (1987) Signal sequence mutations that alter coupling of secretion and translation of an Escherichia coli outer membrane protein. Journal of bacteriology, Vol. 169, H. 10. pp. 4686-4691.

Hall, M. N.. (1986) Considerations on the mechanism of nuclear protein localization in yeast. In: Nucleocytoplasmic transport. Heidelberg, pp. 247-252.

Garcia-Bustos, J. and Heitman, J. and Hall, M. N.. (1986) Nuclear protein localization signals in yeast. In: Yeast cell biology (UCLA-Symposia on molecular and cellular biology, N.S. Vol. 33). Alan R. Liss, Inc., pp. 421-425.

Benson, S. A. and Hall, M. N. and Silhavy, T. J.. (1985) Genetic analysis of protein export in Escherichia coli K12. Annual Review of Biochemistry, 54. pp. 101-134.

Hall, M. N.. (1985) Studies on the mechanism of nuclear protein localization in yeast. In: Protein transport and secretion. New York, pp. 196-200.

Berman, M. L. and Jackson, D. E. and Fowler, A. and Zabin, I. and Christensen, L. and Fiil, N. P. and Hall, M. N.. (1984) Gene fusion techniques: Cloning vectors for manipulating IacZ gene fusions. Gene Analysis Techniques, 1 (3). pp. 43-51.

Hall, M. N. and Hereford, L. and Herskowitz, I.. (1984) Targeting of E. coli beta-galactosidase to the nucleus in yeast. Cell, 36 (4). pp. 1057-1065.

Hall, M. N. and Gabay, J. and Schwartz, M.. (1983) Evidence for a coupling of synthesis and export of an outer membrane protein in Escherichia coli. The EMBO Journal, 2 (1). pp. 15-19.

Taylor, R. K. and Hall, M. N. and Silhavy, T. J.. (1983) Isolation and characterization of mutations altering expression of the major outer membrane porin proteins using the local anaesthetic procaine. Journal of Molecular Biology, 166 (3). pp. 273-282.

Hall, M. N. and Gabay, J. and Debarbouille, M. and Schwartz, M.. (1982) A role for mRNA secondary structure in the control of translation initiation. Nature, 295. pp. 616-618.

Hall, M. N. and Schwartz, M.. (1982) Reconsidering the early steps of protein secretion. Annales de Microbiologie, 133a (1). pp. 123-127.

Hall, M. N. and Schwartz, M. and Silhavy, T. J.. (1982) Sequence information within the lamB genes in required for proper routing of the bacteriophage lambda receptor protein to the outer membrane of Escherichia coli K-12. Journal of Molecular Biology, 156 (1). pp. 93-112.

Hall, M. N. and Silhavy, T. J.. (1981) Genetic analysis of the major outer membrane proteins of Escherichia coli. Annual Review of Genetics, 15. pp. 91-142.

Hall, M. N. and Silhavy, T. J.. (1981) Genetic analysis of the ompB locus in Escherichia coli K-12. Journal of Molecular Biology, 151 (1). pp. 1-15.

Hall, M. N. and Emr, S. D. and Silhavy, T. J.. (1981) Genetic studies on mechanisms of protein localization in Escherichia coli K-12. In: Membrane transport and neuroreceptors. New York, pp. 81-97.

Taylor, R. K. and Hall, M. N. and Enquist, L. and Silhavy, T. J.. (1981) Identification of OmpR : a positive regulatory protein controlling expression of the major outer membrane matrix porin proteins of Escherichia coli K-12. Journal of bacteriology, Vol. 147, H. 1. pp. 255-258.

Hall, M. N. and Silhavy, T. J.. (1981) The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12. Journal of Molecular Biology, 146 (1). pp. 23-43.

Emr, S. D. and Hall, M. N. and Silhavy, T. J.. (1980) A mechanism of protein localization : the signal hypothesis and bacteria. The Journal of cell biology, Vol. 86, H. 3. pp. 701-711.

Hall, M. N. and Emr, S. D. and Silhavy, T. J.. (1980) Genetic studies on mechanisms of protein localization in Escherichia coli K-12. Journal of Supramolecular Structure, 13 (2). pp. 147-163.

Hall, M. N. and Silhavy, T. J.. (1979) Transcriptional regulation of Escherichia coli K-12 major outer membrane protein 1b. Journal of bacteriology, Vol. 140, H. 2. pp. 342-350.

No

Hall, M. N.. (2008) mTOR - what does it do? Transplantation proceedings, 40 (10). S5-S8.

Silhavy, T. J. and Benson, S. A. and Hall, M. N.. (1985) A mechanism to couple transport and export. In: Microbiology - 1985. Washington, pp. 454-458.