Shimobayashi, M. and Hall, M. N.. (2014) Making new contacts : the mTOR network in metabolism and signalling crosstalk. Nature reviews. Molecular cell biology, Vol. 15, H. 3. pp. 155-162.
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Official URL: http://edoc.unibas.ch/dok/A6233690
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Abstract
More than 20 years after its discovery, our understanding of target of rapamycin (TOR) signalling continues to grow. Recent global 'omics' studies have revealed physiological roles of mammalian TOR (mTOR) in protein, nucleotide and lipid synthesis. Furthermore, emerging evidence provides new insight into the control of mTOR by other pathways such as Hippo, WNT and Notch signalling. Together, this progress has expanded the list of downstream effectors and upstream regulators of mTOR signalling.
| Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Growth & Development > Biochemistry (Hall) |
|---|---|
| UniBasel Contributors: | Hall, Michael N. |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Nature Publishing Group |
| ISSN: | 1471-0072 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
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| Last Modified: | 27 Mar 2014 13:13 |
| Deposited On: | 27 Mar 2014 13:13 |
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