Items where Division is "03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Klinische Pharmakologie > Klinische Pharmakologie (Krähenbühl)
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Bouitbir, Jamal and Panajatovic, Miljenko V. and Krähenbühl, Stephan. (2022) Mitochondrial Toxicity Associated with Imatinib and Sorafenib in Isolated Rat Heart Fibers and the Cardiomyoblast H9c2 Cell Line. International journal of molecular sciences, 23 (4). p. 2282.
Roos, Noëmi Johanna and Mancuso, Riccardo Vincenzo and Sanvee, Gerda Mawududzi and Bouitbir, Jamal and Krähenbühl, Stephan. (2022) Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines. Food and Chemical Toxicology, 162. p. 112869.
Bachmann, Fabio. Metabolism and Drug-Drug Interaction Studies of Metamizole in Humans. 2021, Doctoral Thesis, University of Basel, Faculty of Science.
Blaser, Lea S. and Duthaler, Urs and Bouitbir, Jamal and Leuppi-Taegtmeyer, Anne B. and Liakoni, Evangelia and Dolf, Reto and Mayr, Michael and Drewe, Jürgen and Krähenbühl, Stephan and Haschke, Manuel. (2021) Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study. Frontiers in Pharmacology, 12. p. 620635.
Duthaler, Urs and Weber, Michael and Hofer, Lorenz and Chaccour, Carlos and Maia, Marta and Müller, Pie and Krähenbühl, Stephan and Hammann, Felix. (2021) The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes. PLoS Pathogens, 17 (3). e1009382.
Mühlan, Clemens. Clinical pharmacology of daridorexant, a novel dual orexin receptor antagonist. 2021, Doctoral Thesis, University of Basel, Faculty of Medicine.
Panajatovic, Miljenko V. and Singh, Francois and Krähenbühl, Stephan and Bouitbir, Jamal. (2021) Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression. International Journal of Molecular Siences, 22 (9). p. 4950.
Reber, Emilie. Pharmaceutical Aspects of Nutritional Management. 2021, Doctoral Thesis, University of Basel, Faculty of Science.
Bouitbir, Jamal and Alshaikhali, Abdallah and Panajatovic, Miljenko V. and Abegg, Vanessa F. and Paech, Franziska and Krähenbühl, Stephan. (2020) Mechanisms of Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in H9c2 Cells and Mice. European cardiology, 15. e33.
Bouitbir, Jamal and Panajatovic, Miljenko Valentin and Frechard, Theo and Roos, Noëmi Johanna and Krähenbühl, Stephan. (2020) Imatinib and Dasatinib Provoke Mitochondrial Dysfunction Leading to Oxidative Stress in C2C12 Myotubes and Human RD Cells. Frontiers in Pharmacology, 11. p. 1106.
Panajatovic, Miljenko V. and Singh, François and Duthaler, Urs and Krähenbühl, Stephan and Bouitbir, Jamal. (2020) Role of PGC-1-alpha-associated Mitochondrial Biogenesis in Statin-induced Myotoxicity. European cardiology, 15. e35.
Panajatovic, Miljenko Valentin and Singh, François and Krähenbühl, Stephan and Bouitbir, Jamal. (2020) Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression. Biomedicines, 8 (9). p. 351.
Panajatovic, Miljenko Valentin and Singh, François and Roos, Noëmi Johanna and Duthaler, Urs and Handschin, Christoph and Krähenbühl, Stephan and Bouitbir, Jamal. (2020) PGC-1α plays a pivotal role in simvastatin-induced exercise impairment in mice. Acta physiologica (Oxford, England), 228 (4). e13402.
Roos, Noëmi Johanna and Aliu, Diell and Bouitbir, Jamal and Krähenbühl, Stephan. (2020) Lapatinib Activates the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in HepG2 Cells. Frontiers in pharmacology, 11. p. 944.
Roos, Noëmi Johanna and Duthaler, Urs and Bouitbir, Jamal and Krähenbühl, Stephan. (2020) The uricosuric benzbromarone disturbs the mitochondrial redox homeostasis and activates the NRF2 signaling pathway in HepG2 cells. Free radical biology and medicine, 152. pp. 216-226.
Rudin, Deborah and Schmutz, Maurice and Roos, Noëmi Johanna and Bouitbir, Jamal and Krähenbühl, Stephan. (2020) Reactive Metamizole Metabolites Enhance the Toxicity of Hemin on the ATP Pool in HL60 Cells by Inhibition of Glycolysis. Biomedicines, 8 (7). p. 212.
Sanvee, G. M. and Panajatovic, M. and Bouitbir, D. J. and Krähenbühl, Dmdps. (2020) Statins and Insulin Resistance. European cardiology, 15. e44.
Zhou, Xun and Bouitbir, Jamal and Liechti, Matthias E. and Krähenbühl, Stephan and Mancuso, Riccardo V.. (2020) Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones. Cells, 9 (4). p. 965.
Zhou, Xun and Bouitbir, Jamal and Liechti, Matthias E. and Krähenbühl, Stephan and Mancuso, Riccardo V.. (2020) Para; -Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells. International journal of molecular sciences, 21 (8). p. 2841.
Bouitbir, Jamal and Alshaikhali, Abdallah and Panajatovic, Miljenko V. and Abegg, Vanessa F. and Paech, Franziska and Krähenbühl, Stephan. (2019) Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts. Toxicology, 426. p. 152281.
Bouitbir, Jamal and Sanvee, Gerda M. and Panajatovic, Miljenko V. and Singh, François and Krähenbühl, Stephan. (2019) Mechanisms of statin-associated skeletal muscle-associated symptoms. Pharmacological research (154). p. 104201.
Brecht, Karin and Kirchhofer, Carla and Bouitbir, Jamal and Trapani, Francesca and Keiser, Jennifer and Krähenbühl, Stephan. (2019) Exogenous iron increases fasciocidal activity and hepatocellular toxicity of the synthetic endoperoxides OZ78 and MT04. International Journal of Molecular Sciences, 20 (19). p. 4880.
Bühler, Tim and Medinger, Michael and Bouitbir, Jamal and Krähenbühl, Stephan and Leuppi-Taegtmeyer, Anne. (2019) Hepatotoxicity Due to Azole Antimycotic Agents in a HLA B*35:02-Positive Patient. Frontiers in pharmacology, 10. p. 645.
Sanvee, Gerda M. and Bouitbir, Jamal and Krähenbühl, Stephan. (2019) Insulin prevents and reverts simvastatin-induced toxicity in C2C12 skeletal muscle cells. Scientific reports, 9 (1). p. 7409.
Sanvee, Gerda M. and Panajatovic, Miljenko V. and Bouitbir, Jamal and Krähenbühl, Stephan. (2019) Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle. Biochemical pharmacology, 164. pp. 23-33.
Singh, François and Zoll, Joffrey and Duthaler, Urs and Charles, Anne-Laure and Panajatovic, Miljenko V. and Laverny, Gilles and McWilliams, Thomas G. and Metzger, Daniel and Geny, Bernard and Krähenbühl, Stephan and Bouitbir, Jamal. (2019) PGC-1β modulates statin-associated myotoxicity in mice. Archives of Toxicology, 93 (2). pp. 487-504.
Zhou, Xun and Luethi, Dino and Sanvee, Gerda M. and Bouitbir, Jamal and Liechti, Matthias E. and Krähenbühl, Stephan. (2019) Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts. International journal of molecular sciences, 20 (7). p. 1561.
Aubry, Emilie and Aeberhard, Carla and Bally, Lia and Nuoffer, Jean-Marc and Risch, Lorenz and Mühlebach, Stefan and Burgunder, Jean-Marc and Stanga, Zeno. (2018) Are patients affected by mitochondrial disorders at nutritional risk? Nutrition J (Burbank, Los Angeles County, Calif.), 47. pp. 56-62.
Bachmann, Fabio and Duthaler, Urs and Rudin, Deborah and Krähenbühl, Stephan and Haschke, Manuel. (2018) N-demethylation of N-methyl-4-aminoantipyrine, the main metabolite of metamizole. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 120. pp. 172-180.
Berger, Benjamin and Bachmann, Fabio and Duthaler, Urs and Krähenbühl, Stephan and Haschke, Manuel. (2018) Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug. Frontiers in pharmacology, 9. p. 774.
Duthaler, Urs and Berger, Benjamin and Erb, Stefan and Battegay, Manuel and Letang, Emili and Gaugler, Stefan and Natamatungiro, Alex and Mnzava, Dorcas and Donzelli, Massimiliano and Krähenbühl, Stephan and Haschke, Manuel. (2018) Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions. Journal of Antimicrobial Chemotherapy, 73 (10). pp. 2729-2737.
Grünig, David and Duthaler, Urs and Krähenbühl, Stephan. (2018) Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells. Frontiers in pharmacology, 9. p. 257.
Grünig, David and Felser, Andrea and Duthaler, Urs and Bouitbir, Jamal and Krähenbühl, Stephan. (2018) Effect of the Catechol-O-Methyltransferase Inhibitors Tolcapone and Entacapone on Fatty Acid Metabolism in HepaRG Cells. Toxicological sciences, 164 (2). pp. 477-488.
Lüthi, Dino. Pharmacological and toxicological investigations of new psychoactive substances. 2018, Doctoral Thesis, University of Basel, Faculty of Science.
Mingard, Cécile and Paech, Franziska and Bouitbir, Jamal and Krähenbühl, Stephan. (2018) Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines. Journal of applied toxicology : JAT, 38 (3). pp. 418-431.
Paech, Franziska and Abegg, Vanessa F. and Duthaler, Urs and Terracciano, Luigi and Bouitbir, Jamal and Krähenbühl, Stephan. (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology, 409. pp. 13-23.
Paech, Franziska and Mingard, Cécile and Grünig, David and Abegg, Vanessa F. and Bouitbir, Jamal and Krähenbühl, Stephan. (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology, 395. pp. 34-44.
Pottecher, Julien and Adamopoulos, Chris and Lejay, Anne and Bouitbir, Jamal and Charles, Anne-Laure and Meyer, Alain and Singer, Mervyn and Wolff, Valerie and Diemunsch, Pierre and Laverny, Gilles and Metzger, Daniel and Geny, Bernard. (2018) Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways? Frontiers in Physiology, 9. p. 579.
Aeberhard, Carla and Steuer, Christian and Saxer, Christoph and Huber, Andreas and Stanga, Zeno and Mühlebach, Stefan. (2017) Physicochemical stability and compatibility testing of levetiracetam in all-in-one parenteral nutrition admixtures in daily practice. European journal of pharmaceutical sciences, 96. pp. 449-455.
Blaser, Lea and Hassna, Hala and Hofmann, Sarah and Holbro, Andreas and Haschke, Manuel and Rätz Bravo, Alexandra and Zeller, Andreas and Krähenbühl, Stephan and Taegtmeyer, Anne. (2017) Leucopenia associated with metamizole: a case-control study. Swiss medical weekly, 147. w14438.
Bonifacio, Annalisa and Sanvee, Gerda M. and Brecht, Karin and Kratschmar, Denise V. and Odermatt, Alex and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91 (5). pp. 2223-2234.
Brueckner, David and Krähenbühl, Stephan and Zuber, Ulrich and Bonkat, Gernot and Braissant, Olivier. (2017) An alternative sterility assessment for parenteral drug products using isothermal microcalorimetry. Journal of Applied Microbiology, 123 (3). pp. 773-779.
Brueckner, David and Roesti, David and Zuber, Ulrich and Sacher, Meik and Duncan, Derek and Krähenbühl, Stephan and Braissant, Olivier. (2017) Tunable diode laser absorption spectroscopy as method of choice for non-invasive and automated detection of microbial growth in media fills. Talanta, 167. pp. 21-29.
Brueckner, David and Solokhina, Anna and Krähenbühl, Stephan and Braissant, Olivier. (2017) A combined application of tunable diode laser absorption spectroscopy and isothermal micro-calorimetry for calorespirometric analysis. Journal of Microbiological Methods, 139. pp. 210-214.
Charles, Anne-Laure and Guilbert, Anne-Sophie and Guillot, Max and Talha, Samy and Lejay, Anne and Meyer, Alain and Kindo, Michel and Wolff, Valérie and Bouitbir, Jamal and Zoll, Joffrey and Geny, Bernard. (2017) Muscles Susceptibility to Ischemia-Reperfusion Injuries Depends on Fiber Type Specific Antioxidant Level. Frontiers in physiology, 8. p. 52.
Drago, Sara and Imboden, Roger and Schlatter, Philipp and Buylaert, Mirabel and Krähenbühl, Stephan and Drewe, Juergen. (2017) Pharmacokinetics of Transdermal Etofenamate and Diclofenac in Healthy Volunteers. Basic and Clinical Pharmacology and Toxicology, 121 (5). pp. 423-429.
Duthaler, Urs and Berger, Benjamin and Erb, Stefan and Battegay, Manuel and Letang, Emilio and Gaugler, Stefan and Krähenbühl, Stephan and Haschke, Manuel. (2017) Automated high throughput analysis of antiretroviral drugs in dried blood spots. Journal of Mass Spectrometry, 52 (8). pp. 534-542.
Grünig, David and Felser, Andrea and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicology in Vitro, 42. pp. 337-347.
Haegler, Patrizia and Grünig, David and Berger, Benjamin and Terracciano, Luigi and Krähenbühl, Stephan and Bouitbir, Jamal. (2017) Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice. PLoS One, 12 (1). e0171026.
Haegler, Patrizia and Joerin, Lorenz and Krähenbühl, Stephan and Bouitbir, Jamal. (2017) Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents. Toxicological sciences, 157 (1). pp. 183-195.
Krähenbühl, Stephan. (2017) Importance of the skeletal muscle carnitine stores in fuel selection. The Journal of Physiology, 595 (17). pp. 5727-5728.
Krähenbühl, Stephan and Pichler, Werner J.. (2017) Medikamentöse Hepatopathien - Drug-induced liver injury. Therapeutische Umschau, 74 (3). pp. 123-130.
Luethi, Dino and Liechti, Matthias E. and Krähenbühl, Stephan. (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology, 387. pp. 57-66.
Paech, Franziska and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis. Frontiers in Pharmacology, 8. p. 367.
Paech, Franziska and Messner, Simon and Spickermann, Jochen and Wind, Mathias and Schmitt-Hoffmann, Anne-Hortense and Witschi, Anne Therese and Howell, Brett A. and Church, Rachel J. and Woodhead, Jeff and Engelhardt, Marc and Krähenbühl, Stephan and Maurer, Martina. (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Archives of Toxicology, 91 (11). pp. 3647-3662.
Parra-Guillen, Zinnia P. and Berger, Peter B. and Haschke, Manuel and Donzelli, Massimiliano and Winogradova, Daria and Pfister, Bogumila and Früh, Martin and Gillessen, Silke and Krähenbühl, Stephan and Kloft, Charlotte and Joerger, Markus. (2017) Role of Cytochrome P450 3A4 and 1A2 Phenotyping in Patients with Advanced Non-small-Cell Lung Cancer Receiving Erlotinib Treatment. Basic and Clinical Pharmacology and Toxicology, 121 (4). pp. 309-315.
Blaser, Lea-Sara. Clinical safety of metamizole. 2016, Doctoral Thesis, University of Basel, Faculty of Science.
Bonifacio, Annalisa and Mullen, Peter J. and Mityko, Ileana Scurtu and Navegantes, Luiz C. and Bouitbir, Jamal and Krähenbühl, Stephan. (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Archives of Toxicology, 90 (1). pp. 203-215.
Bouitbir, Jamal and Haegler, Patrizia and Singh, François and Joerin, Lorenz and Felser, Andrea and Duthaler, Urs and Krähenbühl, Stephan. (2016) Impaired Exercise Performance and Skeletal Muscle Mitochondrial Function in Rats with Secondary Carnitine Deficiency. Frontiers in Physiology, 7. p. 345.
Bouitbir, Jamal and Singh, François and Charles, Anne-Laure and Schlagowski, Anna-Isabel and Bonifacio, Annalisa and Echaniz-Laguna, Andoni and Geny, Bernard and Krahenbuhl, Stephan and Zoll, Joffrey. (2016) Statins Trigger Mitochondrial Reactive Oxygen Species-Induced Apoptosis in Glycolytic Skeletal Muscle. Antioxidants and Redox Signaling, 24 (2). pp. 84-98.
Kindo, Michel and Gerelli, Sébastien and Bouitbir, Jamal and Hoang Minh, Tam and Charles, Anne-Laure and Mazzucotelli, Jean-Philippe and Zoll, Joffrey and Piquard, François and Geny, Bernard. (2016) Left Ventricular Transmural Gradient in Mitochondrial Respiration Is Associated with Increased Sub-Endocardium Nitric Oxide and Reactive Oxygen Species Productions. Frontiers in Physiology, 7. p. 331.
Novakova, Katerina and Kummer, Oliver and Bouitbir, Jamal and Stoffel, Sonja D. and Hoerler-Koerner, Ulrike and Bodmer, Michael and Roberts, Paul and Urwyler, Albert and Ehrsam, Rolf and Krähenbühl, Stephan. (2016) Effect of l-carnitine supplementation on the body carnitine pool, skeletal muscle energy metabolism and physical performance in male vegetarians. European Journal of Nutrition, 55 (1). pp. 207-217.
Rickli, Anna. Pharmacology of novel psychoactive substances. 2016, Doctoral Thesis, University of Basel, Faculty of Science.
Haegler, Patrizia and Grünig, David and Berger, Benjamin and Krähenbühl, Stephan and Bouitbir, Jamal. (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: a cell model for idiosyncratic toxicity. Toxicology, 336. pp. 48-58.
Roberts, Paul A. and Bouitbir, Jamal and Bonifacio, Annalisa and Singh, François and Kaufmann, Priska and Urwyler, Albert and Krähenbühl, Stephan. (2015) Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency. American Journal of Physiology. Endocrinology and Metabolism, 309 (3). E265-E274.
Bonifacio, Annalisa and Sanvee, Gerda M. and Bouitbir, Jamal and Krähenbühl, Stephan. (2015) The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity. Biochimica et biophysica acta. Molecular cell research, 1853 (8). pp. 1841-1849.
Liakoni, Evangelia and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2015) Hepatotoxicity of New Oral Anticoagulants (NOACs). Drug safety, 38 (8). pp. 711-720.
Ceschi, Alessandro and Heistermann, Elja and Gros, Sonja and Reichert, Cornelia and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2015) Acute sirolimus overdose: a multicenter case series. PLoS ONE, 10 (5). e0128033.
Seeland, Swen and Kettiger, Helene and Murphy, Mark and Treiber, Alexander and Giller, Jasmin and Kiss, Andrea and Sube, Romain and Krähenbühl, Stephan and Hafner, Mathias and Huwyler, Jörg. (2015) ATP-induced cellular stress and mitochondrial toxicity in cells expressing purinergic P2X7 receptor. Pharmacology Research & Perspecitves, 3 (2). e00123.
Sidharta, Patricia N. and Krähenbühl, Stephan and Dingemanse, Jasper. (2015) Pharmacokinetic and pharmacodynamic evaluation of macitentan , a novel endothelin receptor antagonist for the treatment of pulmonary arterial hypertension. Expert opinion on drug metabolism & toxicology, 11 (3). pp. 437-449.
Blaser, Lea S. and Tramonti, Alexandra and Egger, Pascal and Haschke, Manuel and Krähenbühl, Stephan and Rätz Bravo, Alexandra E.. (2015) Hematological safety of metamizole: retrospective analysis of WHO and Swiss spontaneous safety reports. European journal of clinical pharmacology, 71 (2). pp. 209-217.
Collange, O. and Charles, A.-L. and Lavaux, T. and Noll, E. and Bouitbir, J. and Zoll, J. and Chakfé, N. and Mertes, M. and Geny, B.. (2015) Compartmentalization of Inflammatory Response Following Gut Ischemia Reperfusion. European Journal of Vascular and Endovascular Surgery, 49 (1). pp. 60-65.
Sidharta, Patricia N.. Palosuran: clinical pharmacology of a urotensin-II receptor antagonist in type 2 diabetes mellitus. 2015, Doctoral Thesis, University of Basel, Faculty of Science.
Singh, François and Charles, Anne-Laure and Schlagowski, Anna-Isabel and Bouitbir, Jamal and Bonifacio, Annalisa and Piquard, François and Krähenbühl, Stephan and Geny, Bernard and Zoll, Joffrey. (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis. Biochimica et biophysica acta. Molecular cell research, 1853 (7). pp. 1574-1585.
Welzenbach, Karl and Mancuso, Riccardo V. and Krähenbühl, Stephan and Weitz-Schmidt, Gabriele. (2015) A novel multi-parameter assay to dissect the pharmacological effects of different modes of integrin αLβ2 inhibition in whole blood. British Journal of Pharmacology, 172 (20). pp. 4875-4887.
Zoll, Joffrey and Bouitbir, Jamal and Sirvent, Pascal and Klein, Alexis and Charton, Antoine and Jimenez, Liliana and Péronnet, François R. and Geny, Bernard and Richard, Ruddy. (2015) Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection. Drug design, development and therapy, 9. pp. 3589-3597.
Baratli, Yosra and Charles, Anne-Laure and Wolff, Valérie and Ben Tahar, Lotfi and Smiri, Leila and Bouitbir, Jamal and Zoll, Joffrey and Sakly, Mohsen and Auger, Cyril and Vogel, Thomas and Abdelmelek, Hafedh and Tebourbi, Olfa and Geny, Bernard. (2014) Age modulates Fe3O4 nanoparticles liver toxicity: dose-dependent decrease in mitochondrial respiratory chain complexes activities and coupling in middle-aged as compared to young rats. BioMed Research International, 2014. p. 474081.
Bonifacio, Annalisa. Molecular mechanisms of statin-associated myotoxicity. 2014, Doctoral Thesis, University of Basel, Faculty of Science.
Ceschi, Alessandro and Gregoriano, Claudia and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2014) Acute mycophenolate overdose : case series and systematic literature analysis. Expert opinion on drug safety, Vol. 13, H. 5. pp. 525-534.
Detampel, Pascal and Witzigmann, Dominik and Krähenbühl, Stephan and Huwyler, Jörg. (2014) Hepatocyte targeting using pegylated asialofetuin-conjugated liposomes. Journal of drug targeting, Vol. 22, No. 3. pp. 232-241.
Donzelli, Massimiliano and Derungs, Adrian and Serratore, Maria-Giovanna and Noppen, Christoph and Nezic, Lana and Krähenbühl, Stephan and Haschke, Manuel. (2014) The Basel Cocktail for Simultaneous Phenotyping of Human Cytochrome P450 Isoforms in Plasma, Saliva and Dried Blood Spots. Clinical pharmacokinetics, Vol. 53, H. 3. pp. 271-282.
Felser, Andrea and Lindinger, Peter W. and Schnell, Dominik and Kratschmar, Denise V. and Odermatt, Alex and Mies, Suzette and Jenö, Paul and Krähenbühl, Stephan. (2014) Hepatocellular toxicity of benzbromarone : Effects on mitochondrial function and structure. Toxicology, Vol. 324. pp. 136-146.
Felser, Andrea and Stoller, Andrea and Morand, Réjane and Schnell, Dominik and Donzelli, Massimiliano and Terracciano, Luigi and Bouitbir, Jamal and Krähenbühl, Stephan. (2014) Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation. Toxicology, 323. pp. 1-9.
Gregoriano, Claudia and Ceschi, Alessandro and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2014) Acute thiopurine overdose : analysis of reports to a National Poison Centre 1995-2013. PLoS ONE, Vol. 9, H. 1 , e86390.
Guillot, Max and Charles, Anne-Laure and Chamaraux-Tran, Thien Nga and Bouitbir, Jamal and Meyer, Alain and Zoll, Joffrey and Schneider, Francis and Geny, Bernard. (2014) Oxidative stress precedes skeletal muscle mitochondrial dysfunction during experimental aortic cross-clamping but is not associated with early lung, heart, brain, liver, or kidney mitochondrial impairment. Journal of vascular surgery, 60 (4). pp. 1043-1051.e5.
Isner-Horobeti, Marie-Eve and Rasseneur, Laurence and Lonsdorfer-Wolf, Evelyne and Dufour, Stéphane Pascal and Doutreleau, Stéphane and Bouitbir, Jamal and Zoll, Joffrey and Kapchinsky, Sophia and Geny, Bernard and Daussin, Frédéric Nicolas and Burelle, Yan and Richard, Ruddy. (2014) Effect of eccentric versus concentric exercise training on mitochondrial function. Muscle and Nerve , 50 (5). pp. 803-811.
Lejay, Anne and Meyer, Alain and Schlagowski, Anna-Isabel and Charles, Anne-Laure and Singh, François and Bouitbir, Jamal and Pottecher, Julien and Chakfé, Nabil and Zoll, Joffrey and Geny, Bernard. (2014) Mitochondria: mitochondrial participation in ischemia-reperfusion injury in skeletal muscle. The international journal of biochemistry & cell biology, 50. pp. 101-105.
Liakoni, Evangelia and Rätz Bravo, Alexandra E. and Terracciano, Luigi and Heim, Markus and Krähenbühl, Stephan. (2014) Symptomatic hepatocellular liver injury with hyperbilirubinemia in two patients treated with rivaroxaban. JAMA internal medicine, Vol. 174, H. 10. pp. 1683-1686.
Morand, Réjane and Bouitbir, Jamal and Felser, Andrea and Hench, Jürgen and Handschin, Christoph and Frank, Stephan and Krähenbühl, Stephan. (2014) Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. European journal of nutrition, 53 (6). pp. 1313-1325.
Nezic, Lana and Derungs, Adrian and Bruggisser, Marcel and Tschudin-Sutter, Sarah and Krähenbühl, Stephan and Haschke, Manuel. (2014) Therapeutic drug monitoring of once daily aminoglycoside dosing : comparison of two methods and investigation of the optimal blood sampling strategy. European journal of clinical pharmacology, Vol. 70, H. 7. pp. 829-837.
Siller-Matula, J. M. and Trenk, D. and Krähenbühl, S. and Michelson, A. D. and Delle-Karth, G.. (2014) Clinical implications of drug-drug interactions with P2Y12 receptor inhibitors. Journal of thrombosis and haemostasis, Vol. 12, H. 1. pp. 2-13.
Taegtmeyer, Anne B. and Haschke, Manuel and Tchambaz, Lydia and Buylaert, Mirabel and Tschöpl, Martin and Beuers, Ulrich and Drewe, Jürgen and Krähenbühl, Stephan. (2014) A study of the relationship between serum bile acids and propranolol pharmacokinetics and pharmacodynamics in patients with liver cirrhosis and in healthy controls. PLoS ONE, Vol. 9, H. 6 , e97885.
Wuillemin, Natascha and Terracciano, Luigi and Beltraminelli, Helmut and Schlapbach, Christoph and Fontana, Stefano and Krähenbühl, Stephan and Pichler, Werner J. and Yerly, Daniel. (2014) T cells infiltrate the liver and kill hepatocytes in HLA-B(∗)57:01-associated floxacillin-induced liver injury. American journal of pathology, Vol. 184, no. 6. pp. 1677-1682.
Baratli, Yosra and Charles, Anne-Laure and Wolff, Valérie and Ben Tahar, Lotfi and Smiri, Leila and Bouitbir, Jamal and Zoll, Joffrey and Piquard, François and Tebourbi, Olfa and Sakly, Mohsen and Abdelmelek, Hafedh and Geny, Bernard. (2013) Impact of iron oxide nanoparticles on brain, heart, lung, liver and kidneys mitochondrial respiratory chain complexes activities and coupling. Toxicology in Vitro, 27 (8). pp. 2142-2148.
Caduff Good, Angela and Nobel, Daniel and Krähenbühl, Stephan and Geisen, Christof and Henz, Samuel. (2013) Randomised trial of a clinical dosing algorithm to start anticoagulation with phenprocoumon. Swiss medical weekly, Vol. 143 , w13709.
Ceschi, A. and Rauber-Lüthy, C. and Kupferschmidt, H. and Banner, N. R. and Ansari, M. and Krähenbühl, S. and Taegtmeyer, A. B.. (2013) Acute Calcineurin Inhibitor Overdose: Analysis of Cases Reported to a National Poison Center Between 1995 and 2011. American journal of transplantation : official journal of the American Society of Transplant Surgeons (ASTS) and the American Society of Transplantation (AST), Vol. 13 , S. 786–795.
Collange, O. and Charles, A.-L. and Bouitbir, J. and Chenard, M.-P. and Zoll, J. and Diemunsch, P. and Thaveau, F. and Chakfé, N. and Piquard, F. and Geny, B.. (2013) Methylene blue protects liver oxidative capacity after gut ischaemia-reperfusion in the rat. European Journal of Vascular and Endovascular Surgery, 45 (2). pp. 168-175.
Enache, Irina and Charles, Anne-Laure and Bouitbir, Jamal and Favret, Fabrice and Zoll, Joffrey and Metzger, Daniel and Oswald-Mammosser, Monique and Geny, Bernard and Charloux, Anne. (2013) Skeletal muscle mitochondrial dysfunction precedes right ventricular impairment in experimental pulmonary hypertension. Molecular and cellular biochemistry, 373 (1-2). pp. 161-170.
Eschbach, Judith and Sinniger, Jérôme and Bouitbir, Jamal and Fergani, Anissa and Schlagowski, Anna-Isabel and Zoll, Joffrey and Geny, Bernard and René, Frédérique and Larmet, Yves and Marion, Vincent and Baloh, Robert H. and Harms, Matthew B. and Shy, Michael E. and Messadeq, Nadia and Weydt, Patrick and Loeffler, Jean-Philippe and Ludolph, Albert C. and Dupuis, Luc. (2013) Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age. Neurobiology of disease, 58. pp. 220-230.
Felser, Andrea and Blum, Kim and Lindinger, Peter W. and Bouitbir, Jamal and Krähenbühl, Stephan. (2013) Mechanisms of hepatocellular toxicity associated with dronedarone--a comparison to amiodarone. Toxicological sciences, 131 (2). pp. 480-490.
Franz, Carmen C. and Hildbrand, Carole and Born, Christa and Egger, Sabin and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2013) Dose adjustment in patients with liver cirrhosis : impact on adverse drug reactions and hospitalizations. European journal of clinical pharmacology, Vol. 69, H. 8. pp. 1565-1573.
Giger-Pabst, Urs and Lange, Jochen and Maurer, Christoph and Bucher, Carine and Schreiber, Vital and Schlumpf, Rolf and Kocher, Thomas and Schweizer, Walter and Krähenbühl, Stephan and Krähenbühl, Lukas. (2013) Short-term preoperative supplementation of an immunoenriched diet does not improve clinical outcome in well-nourished patients undergoing abdominal cancer surgery. Nutrition, Vol. 29, H. 5. pp. 724-729.
Haschke, Manuel and Schuster, Manfred and Poglitsch, Marko and Loibner, Hans and Salzberg, Marc and Bruggisser, Marcel and Penninger, Joseph and Krähenbühl, Stephan. (2013) Pharmacokinetics and pharmacodynamics of recombinant human angiotensin-converting enzyme 2 in healthy human subjects. Clinical pharmacokinetics, Vol. 52, H. 9. pp. 783-792.
Hirzel, E. and Lindinger, P. W. and Maseneni, S. and Giese, M. and Rhein, V. V. and Eckert, A. and Hoch, M. and Krahenbuhl, S. and Eberle, A. N.. (2013) Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes. Journal of receptors and signal transduction, Vol. 33, H. 5. pp. 304-312.
Krähenbühl, Stephan. (2013) Leicht erhöhte Transaminasen. Therapeutische Umschau, Vol. 70, H. 5. pp. 284-288.
Maseneni, Swarna and Donzelli, Massimiliano and Brecht, Karin and Krähenbühl, Stephan. (2013) Toxicity of thienopyridines on human neutrophil granulocytes and lymphocytes. Toxicology, 308. pp. 11-19.
Morand, Réjane and Donzelli, Massimiliano and Haschke, Manuel and Krähenbühl, Stephan. (2013) Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. Analytical and bioanalytical chemistry, Vol. 405, H. 27. pp. 8829-8836.
Mueller, F. and Büchel, B. and Köberle, D. and Schürch, S. and Pfister, B. and Krähenbühl, St and Froehlich, T. K. and Largiader, C. R. and Joerger, M.. (2013) Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study. Cancer chemotherapy and pharmacology, Vol. 71, H. 2. pp. 361-370.
Talha, Samy and Bouitbir, Jamal and Charles, Anne-Laure and Zoll, Joffrey and Goette-Di Marco, Paola and Meziani, Ferhat and Piquard, François and Geny, Bernard. (2013) Pretreatment with brain natriuretic peptide reduces skeletal muscle mitochondrial dysfunction and oxidative stress after ischemia-reperfusion. Journal of Applied Physiology, 114 (2). pp. 172-179.
Wuillemin, Natascha and Adam, Jacqueline and Fontana, Stefano and Krähenbühl, Stephan and Pichler, Werner J. and Yerly, Daniel. (2013) HLA haplotype determines hapten or p-i T cell reactivity to flucloxacillin. Journal of immunology, Vol. 190, H. 10. pp. 4956-4964.
Zahno, Anja and Bouitbir, Jamal and Maseneni, Swarma and Lindinger, Peter W. and Brecht, Karin and Krähenbühl, Stephan. (2013) Hepatocellular toxicity of clopidogrel: Mechanisms and risk factors. Free radical biology and medicine, 65. pp. 208-216.
Bouitbir, Jamal and Charles, Anne-Laure and Echaniz-Laguna, Andoni and Kindo, Michel and Daussin, Frédéric and Auwerx, Johan and Piquard, François and Geny, Bernard and Zoll, Joffrey. (2012) Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1. European Heart Journal, 33 (11). pp. 1397-1407.
Bouitbir, Jamal and Daussin, Frédéric and Charles, Anne-Laure and Rasseneur, Laurence and Dufour, Stéphane and Richard, Ruddy and Piquard, François and Geny, Bernard and Zoll, Joffrey. (2012) Mitochondria of trained skeletal muscle are protected from deleterious effects of statins. Muscle and Nerve , 46 (3). pp. 367-373.
Daussin, Frédéric N. and Rasseneur, Laurence and Bouitbir, Jamal and Charles, Anne-Laure and Dufour, Stéphane P. and Geny, Bernard and Burelle, Yan and Richard, Ruddy. (2012) Different timing of changes in mitochondrial functions following endurance training. Medicine and Science in Sports and Exercise, 44 (2). pp. 217-224.
Detampel, Pascal and Beck, Mareike and Krähenbühl, Stephan and Huwyler, Jörg. (2012) Drug interaction potential of resveratrol. Drug metabolism reviews, Vol. 44, H. 3. pp. 253-265.
Franz, Carmen C. and Egger, Sabin and Born, Christa and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2012) Potential drug-drug interactions and adverse drug reactions in patients with liver cirrhosis. European journal of clinical pharmacology, Vol. 68, H. 2. pp. 179-188.
Franz, Carmen Carina. Drug-related problems and dosage adjustment in patients with liver disease. 2012, Doctoral Thesis, University of Basel, Faculty of Science.
Hardmeier, M. and Zimmermann, R. and Rüegg, S. and Pflüger, M. and Deuster, S. and Suter, K. and Donzelli, M. and Drewe, J. and Krähenbühl, S. and Fuhr, P. and Haschke, M.. (2012) Intranasal midazolam: pharmacokinetics and pharmacodynamics assessed by quantitative EEG in healthy volunteers. Clinical Pharmacology & Therapeutics, 91 (5). pp. 856-862.
Henkel, Verena and Casaulta, Flurina and Seemüller, Florian and Krähenbühl, Stephan and Obermeier, Michael and Hüsler, Jürg and Möller, Hans-Jürgen. (2012) Study design features affecting outcome in antidepressant trials. Journal of affective disorders, Vol. 141, H. 2-3. pp. 160-167.
Hysek, C. M. and Simmler, L. D. and Nicola, V. G. and Vischer, N. and Donzelli, M. and Krahenbuhl, S. and Grouzmann, E. and Huwyler, J. and Hoener, M. C. and Liechti, M. E.. (2012) Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study. PLoS ONE, Vol. 7, H. 5 , e36476.
Joerger, M. and Ferreri, A. J. M. and Krähenbühl, S. and Schellens, J. H. M. and Cerny, Th and Zucca, E. and Huitema, A. D. R.. (2012) Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate. British journal of clinical pharmacology, Vol. 73, H. 2. pp. 240-247.
Kindo, Michel and Gerelli, Sébastien and Bouitbir, Jamal and Charles, Anne-Laure and Zoll, Joffrey and Hoang Minh, Tam and Monassier, Laurent and Favret, Fabrice and Piquard, François and Geny, Bernard. (2012) Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress. Frontiers in physiology, 3. p. 332.
Mansour, Ziad and Bouitbir, Jamal and Charles, Anne Laure and Talha, Samy and Kindo, Michel and Pottecher, Julien and Zoll, Joffrey and Geny, Bernard. (2012) Remote and local ischemic preconditioning equivalently protects rat skeletal muscle mitochondrial function during experimental aortic cross-clamping. Journal of vascular surgery, 55 (2). pp. 497-505.e1.
Mansour, Ziad and Charles, Anne L. and Bouitbir, Jamal and Pottecher, Julien and Kindo, Michel and Mazzucotelli, Jean-Philippe and Zoll, Joffrey and Geny, Bernard. (2012) Remote and local ischemic postconditioning further impaired skeletal muscle mitochondrial function after ischemia-reperfusion. Journal of vascular surgery, 56 (3). pp. 774-782.e1.
Maseneni, Swarna and Donzelli, Massimiliano and Taegtmeyer, A. B. and Brecht, Karin and Krähenbühl, Stephan. (2012) Toxicity of clopidogrel and ticlopidine on human myeloid progenitor cells: importance of metabolites. Toxicology, 299 (2-3). pp. 139-145.
Morand, R. and Todesco, L. and Donzelli, M. and Fischer-Barnicol, D. and Mullen, P. J. and Krahenbuhl, S.. (2012) Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans. Therapeutic drug monitoring, Vol. 34, H. 4. pp. 406-414.
Nezic, L. and Krähenbühl, S. and Rätz Bravo, A. E.. (2012) Diclofenac-induzierte Leberschäden = Diclofenac induced liver injuries. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine PRAXIS, Vol. 101, H. 6. pp. 371-379.
Noll, E. and Bouitbir, J. and Collange, O. and Zoll, J. and Charles, A. L. and Thaveau, F. and Diemunsch, P. and Geny, B.. (2012) Local but not systemic capillary lactate is a reperfusion biomarker in experimental acute limb ischaemia. European Journal of Vascular and Endovascular Surgery, 43 (3). pp. 339-340.
Pham, T. T. T. and See, H. H. and Morand, R. and Krahenbuhl, S. and Hauser, P. C.. (2012) Determination of free and total valproic acid in human plasma by capillary electrophoresis with contactless conductivity detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Vol. 907. pp. 74-78.
See, Hong Heng and Schmidt-Marzinkowski, Julia and Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2012) Determination of creatine and phosphocreatine in muscle biopsy samples by capillary electrophoresis with contactless conductivity detection. Analytica Chimica Acta, 727. pp. 78-82.
Mühlebach, Stefan. (18 October 2011) Dietary supplements : Erfindungen versus Wissenschaft. Aerztewoche : Österreichische Zeitschrift für Medizin, Gesundheitspolitik und Praxismanagement, 42 (4). p. 29.
Becker, C. and Brobert, G. P. and Johansson, S. and Jick, S. S. and Meier, C. R.. (2011) Risk of incident depression in patients with Parkinson disease in the UK. European Journal of Neurology, 18 (3). pp. 448-453.
Becker, C. and Jick, S. S. and Meier, C. R.. (2011) NSAID use and risk of Parkinson disease : a population-based case-control study. European Journal of Neurology, 18 (11). pp. 1336-1342.
Bodmer, Michael and Becker, Claudia and Meier, Christian and Jick, Susan S. and Meier, Christoph R.. (2011) Use of metformin and the risk of ovarian cancer: a case-control analysis. Gynecologic oncology, 123 (2). pp. 200-204.
Bodmer, Michael and Brauchli, Yolanda B. and Jick, Susan S. and Meier, Christoph R.. (2011) Diabetes mellitus and the risk of cholecystectomy. Digestive and liver disease, Vol. 43, H. 9. pp. 742-747.
Bouitbir, Jamal and Charles, Anne-Laure and Rasseneur, Laurence and Dufour, Stéphane and Piquard, François and Geny, Bernard and Zoll, Joffrey. (2011) Atorvastatin treatment reduces exercise capacities in rats: involvement of mitochondrial impairments and oxidative stress. Journal of Applied Physiology, 111 (5). pp. 1477-1483.
Brauchli, Yolanda B. and Jick, Susan S. and Meier, Christoph R.. (2011) Statin use and risk of first-time psoriasis diagnosis. Journal of the American Academy of Dermatology, Vol. 65, H. 1. pp. 77-83.
Bruggisser, M. and Rätz Bravo, A. E. and Krähenbühl, S.. (2011) [Severe pancytopenia and stomatitis in a patient treated with low-dose methostraxate]. Schweizerische Rundschau für Medizin PRAXIS, Vol. 100, H. 13 , S. 765-774; quiz 772.
Charles, A.-L. and Guilbert, A.-S. and Bouitbir, J. and Goette-Di Marco, P. and Enache, I. and Zoll, J. and Piquard, F. and Geny, B.. (2011) Effect of postconditioning on mitochondrial dysfunction in experimental aortic cross-clamping. The British journal of surgery, 98 (4). pp. 511-516.
Collange, Olivier and Charles, Anne-Laure and Noll, Eric and Bouitbir, Jamal and Zoll, Joffrey and Piquard, François and Diemunsch, Pierre and Geny, Bernard. (2011) Isoflurane anesthesia preserves liver and lung mitochondrial oxidative capacity after gut ischemia-reperfusion. Anesthesia and Analgesia, 113 (6). pp. 1438-1441.
Derungs, Adrian and Schietzel, Simeon and Meyer, Markus R. and Maurer, Hans H. and Krähenbühl, Stephan and Liechti, Matthias E.. (2011) Sympathomimetic toxicity in a case of analytically confirmed recreational use of naphyrone (naphthylpyrovalerone). Clinical toxicology, 49 (7). pp. 691-693.
Franz, C. C. and Bruggisser, M. and Krähenbühl, S. and Rätz Bravo, A. E.. (2011) [Rhabdomyolysis associated with atorvastatin combined with amiodarone and fluconazole]. Schweizerische Rundschau für Medizin PRAXIS, Vol. 100, H. 5. pp. 273-284.
Giger, U. and Ouaissi, M. and Schmitz, S.-F H. and Krähenbühl, S. and Krähenbühl, L.. (2011) Bile duct injury and use of cholangiography during laparoscopic cholecystectomy. British journal of surgery, Vol. 98, H. 3. pp. 391-396.
Halter, J. and Schüpbach, W. M. M. and Casali, C. and Elhasid, R. and Fay, K. and Hammans, S. and Illa, I. and Kappeler, L. and Krähenbühl, S. and Lehmann, T. and Mandel, H. and Marti, R. and Mattle, H. and Orchard, K. and Savage, D. and Sue, C. M. and Valcarcel, D. and Gratwohl, A. and Hirano, M.. (2011) Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) : a consensus conference proposal for a standardized approach. Bone marrow transplantation, Vol. 46, H. 3. pp. 330-337.
Halter, Joerg and Schüpbach, W. M. Michael and Casali, Carlo and Elhasid, Ronit and Fay, K. and Hammans, S. and Illa, I. and Kappeler, Liliane and Krähenbühl, Stephan and Lehmann, T. and Mandel, H. and Marti, Ramon and Mattle, Heinrich P. and Orchard, Kim and Savage, David and Sue, Carolyn M. and Valcarcel, David and Gratwohl, Alois and Hirano, M.. (2011) Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a consensus conference proposal for a standardized approach. Bone marrow transplantation, 46 (3). pp. 330-337.
Hoch, Matthias and Hoever, Petra and Haschke, Manuel and Krähenbühl, Stephan and Dingemanse, Jasper. (2011) Food effect and biocomparison of two formulations of the dual orexin receptor antagonist almorexant in healthy male subjects. The journal of clinical pharmacology, Vol. 51, H. 7. pp. 1116-1121.
Kummer, Oliver and Hammann, Felix and Moser, Claudine and Schaller, Olivier and Drewe, Jürgen and Krähenbühl, Stephan. (2011) Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. European journal of clinical pharmacology, Vol. 67, H. 1. pp. 63-71.
Meier, Christoph R.. (2011) Risiken oraler Kontrazeptiva. Therapeutische Umschau, 68 (6). pp. 345-352.
Meyer-Massetti, Carla and Cheng, Christine M. and Schwappach, David L. B. and Paulsen, Lynn and Ide, Brigid and Meier, Christoph R. and Guglielmo, B. Joseph. (2011) Systematic review of medication safety assessment methods. American journal of health system pharmacy, Vol. 68, H. 3. pp. 227-240.
Meyer-Massetti, Carla and Vaerini, Simone and Rätz Bravo, Alexandra E. and Meier, Christoph R. and Guglielmo, B. Joseph. (2011) Comparative safety of antipsychotics in the WHO pharmacovigilance database : the haloperidol case. International journal of clinical pharmacy, Vol. 33, H. 5. pp. 806-814.
Mullen, Peter J. and Zahno, Anja and Lindinger, Peter and Maseneni, Swarma and Felser, Andrea and Krähenbühl, Stephan and Brecht, Karin. (2011) Susceptibility to simvastatin-induced toxicity is partly determined by mitochondrial respiration and phosphorylation state of Akt. Biochimica et biophysica acta, Vol. 1813, H. 12. pp. 2079-2087.
Mühlebach, Stefan and Driscoll, David F. and Hardy, Gil. (2011) How to prepare parenteral nutrition (PN) admixtures, role and function of the pharmacist. In: Basics in clinical nutrition. Prague, pp. 373-384.
Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2011) Capillary electrophoresis with contactless conductivity detection for the determination of carnitine and acylcarnitines in clinical samples. Journal of Chromatography B, 879 (13-14). pp. 921-926.
Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2011) Quantification of plasma lactate concentrations using capillary electrophoresis with contactless conductivity detection. Electrophoresis, 32 (8). pp. 884-889.
Steinert, Robert E. and Frey, Florian and Töpfer, Antonia and Drewe, Jürgen and Beglinger, Christoph. (2011) Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides. The British journal of nutrition, Vol. 105, H. 9. pp. 1320-1328.
Toovey, Stephen and Jick, Susan S. and Meier, Christoph R.. (2011) Parkinson's disease or Parkinson symptoms following seasonal influenza. Influenza and other respiratory viruses, Vol. 5, H. 5. pp. 328-333.
Zahno, Anja and Brecht, Karin and Morand, Réjane and Maseneni, Swarna and Török, Michael and Lindinger, Peter W. and Krähenbühl, Stephan. (2011) The role of CYP3A4 in amiodarone-associated toxicity on HepG2 cells. Biochemical pharmacology, Vol. 81, Issue 3. pp. 432-441.
Becker, Claudia and Bray-French, Katharine and Drewe, Juergen. (2010) Pharmacokinetic evaluation of idebenone. Expert opinion on drug metabolism & toxicology, Vol. 6, H. 11. pp. 1437-1444.
Becker, Claudia and Brobert, Gunnar P. and Johansson, Saga and Jick, Susan S. and Meier, Christoph R.. (2010) Cancer risk in association with Parkinson disease : a population-based study. Parkinsonism & related disorders, 16 (3). pp. 186-190.
Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2010) Risk of stroke in patients with idiopathic Parkinson disease. Parkinsonism & related disorders, 16 (1). pp. 31-35.
Beglinger, Svetlana and Drewe, Juergen and Schirra, Joerg and Göke, Burkhard and D'Amato, Massimo and Beglinger, Christoph. (2010) Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion. Journal of clinical endocrinology and metabolism, Vol. 95, H. 2. pp. 879-886.
Bodmer, Michael and Meier, Christian and Kraenzlin, Marius E. and Meier, Christoph R.. (2010) Proton pump inhibitors and fracture risk: true effect or residual confounding? Drug safety, 33 (10). pp. 843-852.
Bodmer, Michael and Meier, Christian and Krähenbühl, Stephan and Jick, Susan S. and Meier, Christoph R.. (2010) Long-term metformin use is associated with decreased risk of breast cancer. Diabetes care, Vol. 33, H. 6. pp. 1304-1308.
Brauchli, Yolanda B. and Wais, Thomas and Gratwohl, Alois and Heim, Dominik and Schipf, Alexander and Diebold, Joachim and Krähenbühl, Stephan. (2010) Fatal myocardial infarction during nilotinib treatment in a 60-year-old male patient. Acta oncologica, Vol. 49, no. 4. pp. 523-525.
Egger, S. S. and Meier, S. and Leu, C. and Christen, S. and Gratwohl, A. and Krahenbuhl, S. and Haschke, M.. (2010) Drug interactions and adverse events associated with antimycotic drugs used for invasive aspergillosis in hematopoietic SCT. Bone marrow transplantation, Vol. 45, H. 7. pp. 1197-1203.
Frey Tirri, B. and Bitzer, J. and Geudelin, B. and Drewe, J.. (2010) Safety, tolerability and pharmacokinetics of intravaginal pentamycin. Chemotherapy, 56 (3). pp. 190-196.
Graber-Maier, Angelika and Büter, Karin Berger and Aeschlimann, Julia and Bittel, Claudia and Kreuter, Matthias and Drewe, Juergen and Gutmann, Heike. (2010) Effects of Curcuma Extracts and Curcuminoids on Expression of P-glycoprotein and Cytochrome P450 3A4 in the Intestinal Cell Culture Model LS180. Planta medica, Vol. 76, H. 16. pp. 1866-1870.
Grisouard, Jean and Timper, Katharina and Radimerski, Tanja M. and Frey, Daniel M. and Peterli, Ralph and Kola, Blerina and Korbonits, Marta and Herrmann, Paul and Krahenbuhl, Stephan and Zulewski, Henryk and Keller, Ulrich and Muller, Beat and Christ-Crain, Mirjam. (2010) Mechanisms of metformin action on glucose transport and metabolism in human adipocytes. Biochemical Pharmacology, 80 (11). pp. 1736-1745.
Hammann, F. and Gutmann, H. and Vogt, N. and Helma, C. and Drewe, J.. (2010) Prediction of adverse drug reactions using decision tree modeling. Clinical pharmacology and therapeutics, Vol. 88, H. 1. pp. 52-59.
Hammann, Felix and Drewe, Jürgen. (2010) Medikamentöse Therapieansätze des Delirs. Therapeutische Umschau, 67 (2). pp. 91-94.
Haschke, M. and Vitins, T. and Lude, S. and Todesco, L. and Novakova, K. and Herrmann, R. and Krahenbuhl, S.. (2010) Urinary excretion of carnitine as a marker of proximal tubular damage associated with platin-based antineoplastic drugs. Nephrology, dialysis, transplantation, Vol. 25, H. 2. pp. 426-433.
Haschke, Manuel and Suter, Katja and Hofmann, Sarah and Witschi, Robert and Fröhlich, Johannes and Imanidis, Georgios and Drewe, Jürgen and Briellmann, Thomas A. and Dussy, Franz E. and Krähenbühl, Stephan and Surber, Christian. (2010) Pharmacokinetics and pharmacodynamics of nasally delivered midazolam. British journal of clinical pharmacology, Vol. 69, H. 6. pp. 607-616.
Joerger, M. and Huitema, A. D. R. and Krähenbühl, S. and Schellens, J. H. M. and Cerny, T. and Reni, M. and Zucca, E. and Cavalli, F. and Ferreri, A. J. M.. (2010) Methotrexate area under the curve is an important outcome predictor in patients with primary CNS lymphoma : a pharmacokinetic-pharmacodynamic analysis from the IELSG no. 20 trial. British journal of cancer, Vol. 102, H. 4. pp. 673-677.
Krämer, Isabel and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Krähenbühl, Stephan and Ceschi, Alessandro. (2010) Minimal dose for severe poisoning and influencing factors in acute human clozapine intoxication : a 13-year retrospective study. Clinical neuropharmacology, Vol. 33, H. 5. pp. 230-234.
Meier, Christian and Brauchli, Yolanda B. and Jick, Susan S. and Kraenzlin, Marius E. and Meier, Christoph R.. (2010) Use of depot medroxyprogesterone acetate and fracture risk. Journal of clinical endocrinology and metabolism, Vol. 95, H. 11. pp. 4909-4916.
Mullen, Peter James and Lüscher, Barbara and Scharnagl, Hubert and Krähenbühl, Stephan and Brecht, Karin. (2010) Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy. Biochemical pharmacology, 79 (8). pp. 1200-1209.
Mühlebach, Stefan and Radziwil, Roland and Dörje, Frank. (2010) Ernährungstherapie. In: Klinische Pharmazie. Grundlagen und Anwendung. Stuttgart, pp. 289-318.
Poller, Birk and Drewe, Jürgen and Krähenbühl, Stephan and Huwyler, Jörg and Gutmann, Heike. (2010) Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier. Cellular and Molecular Neurobiology, Vol. 30, No. 1. pp. 63-70.
Popov, Yury and Sverdlov, Deanna Y. and Bhaskar, K. Ramakrishnan and Sharma, Anisha K. and Millonig, Gunda and Patsenker, Eleonora and Krahenbuhl, Stephan and Krahenbuhl, Lukas and Schuppan, Detlef. (2010) Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis. American journal of physiology. Gastrointestinal and liver physiology, Vol. 298, H. 3 , G323-334.
Pormsila, W. and Krähenbühl, S. and Hauser, P. C.. (2010) Determination of carnitine in food and food supplements by capillary electrophoresis with contactless conductivity detection. Electrophoresis, Vol. 31. pp. 2186-2191.
Sawatzki, M. and Kummer, O. and Krähenbühl, S. and Siegemund, M.. (2010) 35-jährige Patientin mit generalisiertem Krampfanfall und nicht-kardiogenem Lungenödem nach Intoxikation. Internist, 51 (4). pp. 528-532.
Schaer, Beat A. and Schneider, Cornelia and Jick, Susan S. and Conen, David and Osswald, Stefan and Meier, Christoph R.. (2010) Risk for incident atrial fibrillation in patients who receive antihypertensive drugs: a nested case-control study. Annals of internal medicine, Vol. 152, H. 2. pp. 78-84.
Schneider, Cornelia and Bothner, Ulrich and Jick, Susan S. and Meier, Christoph R.. (2010) Chronic obstructive pulmonary disease and the risk of cardiovascular diseases. European journal of epidemiology, Vol. 25, H. 4. pp. 253-260.
Schneider, Cornelia and Jick, Susan S. and Bothner, Ulrich and Meier, Christoph R.. (2010) COPD and the risk of depression. Chest, 137 (2). pp. 341-347.
Schneider, Cornelia and Jick, Susan S. and Bothner, Ulrich and Meier, Christoph R.. (2010) Reflux disease, gastrointestinal ulcer or weight loss in patients with COPD. COPD, Vol. 7, H. 3. pp. 172-178.
Schürch, Regula and Todesco, Liliane and Novakova, Katarina and Mevissen, Meike and Stieger, Bruno and Krähenbühl, Stephan. (2010) The plasma carnitine concentration regulates renal OCTN2 expression and carnitine transport in rats. European journal of pharmacology, Vol. 635, H. 1-3. pp. 171-176.
Steinert, Robert E. and Poller, Birk and Castelli, M. Cristina and Drewe, Juergen and Beglinger, Christoph. (2010) Oral administration of glucagon-like peptide 1 or peptide YY 3-36 affects food intake in healthy male subjects. American journal of clinical nutrition, Vol. 92, H. 4. pp. 810-817.
Sturm, Stefan and Hammann, Felix and Drewe, Juergen and Maurer, Hans H. and Scholer, André. (2010) An automated screening method for drugs and toxic compounds in human serum and urine using liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Vol. 878, H. 28. pp. 2726-2732.
Thaveau, Fabien and Zoll, Joffrey and Bouitbir, Jamal and N'guessan, Benoît and Plobner, Philippe and Chakfe, Nabil and Kretz, Jean-Georges and Richard, Ruddy and Piquard, François and Geny, Bernard. (2010) Effect of chronic pre-treatment with angiotensin converting enzyme inhibition on skeletal muscle mitochondrial recovery after ischemia/reperfusion. Fundamental & Clinical Pharmacology, 24 (3). pp. 333-340.
Zahno, Anja and Brecht, Karin and Bodmer, Michael and Bur, Daniel and Tsakiris, Dimitrios A. and Krähenbühl, Stephan. (2010) Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. British journal of pharmacology, 161 (2). pp. 393-404.
Becker, Claudia and Meier, Christoph R.. (2009) Statins and the risk of Parkinson disease : an update on the controversy. Expert opinion on drug safety, Vol. 8, H. 3. pp. 261-271.
Bodmer, M. and Haschke, M. and Bravo, Rätz and Liechti, M. E.. (2009) Nierenversagen und hämolytische Anämie = Acute renal failure due to rifampicine. Schweizerische Rundschau für Medizin Praxis, Jg. 98, Nr. 4. pp. 179-185.
Bodmer, Michael and Brauchli, Yolanda B. and Krähenbühl, Stephan and Jick, Susan S. and Meier, Christoph R.. (2009) Statin use and risk of gallstone disease followed by cholecystectomy. JAMA : the journal of the American Medical Association, Vol. 302, H. 18. pp. 2001-2007.
Bodmer, Michael and Meier, Christian and Kraenzlin, Marius E. and Meier, Christoph R.. (2009) Risk of fractures with glitazones : a critical review of the evidence to date. Drug safety, Vol. 32, no. 7. pp. 539-547.
Bodmer, Michael and Vankan, Pierre and Dreier, Manfred and Kutz, Klaus W. and Drewe, Jürgen. (2009) Pharmacokinetics and metabolism of idebenone in healthy male subjects. European journal of clinical pharmacology : pharmacologia clinica : EJCP, Vol. 65. pp. 493-501.
Brauchli, Y. B. and Jick, S. S. and Miret, M. and Meier, C. R.. (2009) Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack : an inception cohort study with a nested case-control analysis. British journal of dermatology, Vol. 160, H. 5. pp. 1048-1056.
Brauchli, Yolanda B. and Jick, Susan S. and Curtin, François and Meier, Christoph R.. (2009) Lithium, antipsychotics, and risk of psoriasis. Journal of clinical psychopharmacology, Vol. 29, H. 2. pp. 134-140.
Brauchli, Yolanda B. and Jick, Susan S. and Miret, Montserrat and Meier, Christoph R.. (2009) Psoriasis and risk of incident cancer : an inception cohort study with a nested case-control analysis. Journal of investigative dermatology, Vol. 129, no. 11. pp. 2604-2612.
Brill, Shlomo and Zimmermann, Christian and Berger, Karin and Drewe, Juergen and Gutmann, Heike. (2009) In vitro interactions with repeated grapefruit juice administration--to peel or not to peel? Planta medica : Zeitschrift für Arzneipflanzenforschung : official organ of the Society for Medicinal Plant Research, Vol. 75. pp. 332-335.
Fiegler, K. and Liechti, M. E. and Bodmer, M. and Bruggisser, M.. (2009) Akzidentelle Lithiumintoxikation = Intoxication with lithium. Schweizerische Rundschau für Medizin Praxis, Jg. 98, Nr. 13. pp. 685-691.
Giger, U. and Wente, M. N. and Büchler, M. W. and Krähenbühl, S. and Lerut, J. and Krähenbühl, L.. (2009) Endoscopic retroperitoneal neurectomy for chronic pain after groin surgery. British journal of surgery, Vol. 96, H. 9. pp. 1076-1081.
Hammann, Felix and Gutmann, Heike and Baumann, Ulli and Helma, Christoph and Drewe, Juergen. (2009) Classification of cytochrome p(450) activities using machine learning methods. Molecular pharmaceutics, Vol. 6, H. 6. pp. 1920-1926.
Hammann, Felix and Gutmann, Heike and Jecklin, Ursula and Maunz, Andreas and Helma, Christoph and Drewe, Juergen. (2009) Development of decision tree models for substrates, inhibitors, and inducers of p-glycoprotein. Current drug metabolism, Vol. 10. pp. 339-346.
Kummer, Oliver and Haschke, Manuel and Hammann, Felix and Bodmer, Michael and Bruderer, Shirin and Regnault, Yann and Dingemanse, Jasper and Krähenbühl, Stephan. (2009) Comparison of the dissolution and pharmacokinetic profiles of two galenical formulations of the endothelin receptor antagonist macitentan. European journal of pharmaceutical sciences, Vol. 38, H. 4. pp. 384-388.
Kutz, Klaus and Drewe, Jürgen and Vankan, Pierre. (2009) Pharmacokinetic properties and metabolism of idebenone. Journal of neurology : official journal of the European Neurological Society ... [et al.] = Zeitschrift für Neurologie, Vol. 256. pp. 31-35.
MacLean, Carol M. and Casanova, Anna-Tina and Baselgia-Jeker, Luisa and Neave, Nicola and Larsen, Finn and Skillern, Laurence and Drewe, Juergen and Beglinger, Christoph. (2009) Effect of food on the pharmacokinetics and pharmacodynamics of an oral ghrelin agonist (ARD-07) in healthy subjects. The journal of clinical pharmacology : official publication of the American College of Clinical Pharmacology, Vol. 49. pp. 553-559.
Meier, C. and Bodmer, M. and Meier, C. R. and Kraenzlin, M. E.. (2009) [Thiazolidinediones and skeletal health]. Revue médicale suisse, Vol. 5, H. 207 , S. 1309-1310, 1312-1313.
Peterli, Ralph and Wölnerhanssen, Bettina and Peters, Thomas and Devaux, Noémie and Kern, Beatrice and Christoffel-Courtin, Caroline and Drewe, Juergen and von Flüe, Markus and Beglinger, Christoph. (2009) Improvement in glucose metabolism after bariatric surgery : comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy : a prospective randomized trial. Annals of surgery : a monthly review of surgical science and practice, Vol. 250. pp. 234-241.
Pormsila, W. and Krahenbuhl, S. and Hauser, P. C.. (2009) Capillary electrophoresis with contactless conductivity detection for uric acid determination in biological fluids. Analytica Chimica Acta, Vol. 636, pp. 224-228.
Ruppen, W. and Steiner, L. A. and Drewe, J. and Hauenstein, L. and Brugger, S. and Seeberger, M. D.. (2009) Bupivacaine concentrations in the lumbar cerebrospinal fluid of patients during spinal anaesthesia. BJA : British journal of anaesthesia, Vol. 102. pp. 832-838.
Rätz Bravo, Alexandra E. and Hofer, Silvia and Krähenbühl, Stephan and Ludwig, Christian. (2009) Fatal drug-drug interaction of brivudine and capecitabine. Acta oncologica, Vol. 48, no. 4. pp. 631-633.
Schlatter, Chantal and Egger, Sabin S. and Tchambaz, Lydia and Krähenbühl, Stephan. (2009) Pharmacokinetic changes of psychotropic drugs in patients with liver disease : implications for dose adaptation. Drug safety, Vol. 32, no. 7. pp. 561-578.
Schneider, C. and Jick, S. S. and Meier, C. R.. (2009) Risk of cardiovascular outcomes in users of estradiol/dydrogesterone or other HRT preparations. Climacteric, 12 (5). pp. 445-453.
Schneider, C. and Jick, S. S. and Meier, C. R.. (2009) Risk of gynecological cancers in users of estradiol/dydrogesterone or other HRT preparations. Climacteric, 12 (6). pp. 514-524.
Sidharta, P. N. and Rave, K. and Heinemann, L. and Chiossi, E. and Krahenbuhl, S. and Dingemanse, J.. (2009) Effect of the urotensin-II receptor antagonist palosuran on secretion of and sensitivity to insulin in patients with Type 2 diabetes mellitus. British journal of clinical pharmacology, Vol. 68, no. 4. pp. 502-510.
Smieskova, R. and Fusar-Poli, P. and Allen, P. and Bendfeldt, K. and Stieglitz, R. D. and Drewe, J. and Radue, E. W. and McGuire, P. K. and Riecher-Rössler, A. and Borgwardt, S. J.. (2009) The Effects of Antipsychotics on the Brain: What Have We Learnt from Structural Imaging of Schizophrenia? - A Systematic Review. Current Pharmaceutical Design, 15 (22). pp. 2535-2549.
Steinert, R. E. and Poller, B. and Castelli, M. C. and Friedman, K. and Huber, A. R. and Drewe, J. and Beglinger, C.. (2009) Orally administered glucagon-like peptide-1 affects glucose homeostasis following an oral glucose tolerance test in healthy male subjects. Clinical pharmacology and therapeutics : official publication of the American Society for Clinical Pharmacology and Therapeutics and the American Society for Pharmacology and Experimental Therapeutics, Vol. 86, H. 6. pp. 644-650.
Thaveau, Fabien and Zoll, Joffrey and Bouitbir, Jamal and Ribera, Florence and Di Marco, Paola and Chakfe, Nabil and Kretz, Jean Georges and Piquard, Francois and Geny, Bernard. (2009) Contralateral leg as a control during skeletal muscle ischemia-reperfusion. Journal of surgical research, 155 (1). pp. 65-69.
Todesco, Liliane and Bodmer, Michael and Vonwil, Karin and Häussinger, Daniel and Krähenbühl, Stephan. (2009) Interaction between pivaloylcarnitine and L-carnitine transport into L6 cells overexpressing hOCTN2. Chemico-Biological Interactions , 180 (3). pp. 472-477.
Wojtal, Kacper A. and Eloranta, Jyrki J. and Hruz, Petr and Gutmann, Heike and Drewe, Jürgen and Staumann, Alex and Beglinger, Christoph and Fried, Michael and Kullak-Ublick, Gerd A. and Vavricka, Stephan R.. (2009) Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients. Drug metabolism and disposition : the biological fate of chemicals, Vol. 37. pp. 1871-1877.
Aschmann, Yvonne Zysset and Kummer, Oliver and Linka, André and Wenk, Markus and Azzola, Andrea and Bodmer, Michael and Krähenbühl, Stephan and Haschke, Manuel. (2008) Pharmacokinetics and pharmacodynamics of sildenafil in a patient treated with human immunodeficiency virus protease inhibitors. Therapeutic drug monitoring, Vol. 30, H. 1. pp. 130-134.
Becker, C. and Brobert, G. P. and Almqvist, P. M. and Johansson, S. and Jick, S. S. and Meier, C. R.. (2008) Migraine incidence, comorbidity and health resource utilization in the UK. Studies in modern thermodynamics, 3. pp. 57-64.
Becker, Claudia and Brobert, Gunnar P. and Almqvist, Per M. and Johansson, Saga and Jick, Susan S. and Meier, Christoph R.. (2008) The risk of newly diagnosed asthma in migraineurs with or without previous triptan prescriptions. Headache, 48 (4). pp. 606-610.
Becker, Claudia and Brobert, Gunnar P. and Johansson, Saga and Jick, Susan S. and Meier, Christoph R.. (2008) Diabetes in patients with idiopathic Parkinson's disease. Diabetes Care, 31 (9). pp. 1808-1812.
Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2008) Use of antihypertensives and the risk of Parkinson disease. Neurology, 70 (16 Pt. 2). pp. 1438-1444.
Becker, Claudia and Jick, Susan S. and Meier, Christoph R.. (2008) Use of statins and the risk of Parkinson's disease: a retrospective case-control study in the UK. Drug safety, 31 (5). pp. 399-407.
Bodmer, M. and Burkard, T. and Kummer, O. and Beyrau, R. and Krähenbühl, S. and Haschke, M.. (2008) Pharmacokinetics and pharmacodynamics of quetiapine in a patient with a massive overdose. Therapeutic drug monitoring, Vol. 30, H. 4. pp. 553-556.
Bodmer, M. and Christ, A. and Liechti, M. E.. (2008) Intoxikation mit einem unbekannten Sedativum = Intoxication with an unknown sedative substance. Schweizerische Rundschau für Medizin Praxis, Jg. 97, Nr. 15. pp. 820-825.
Bodmer, M. and Link, B. and Grignaschi, N. and Kummer, O. and Ruegg, S. and Haschke, M. and Krähenbühl, S.. (2008) Pharmacokinetics of midazolam and metabolites in a patient with refractory status epilepticus treated with extraordinary doses of midazolam. Therapeutic drug monitoringNew York : Raven Press, Vol. 30, H. 1. pp. 120-124.
Bodmer, M. and Meier, C. and Krähenbühl, S. and Jick, S. S. and Meier, C. R.. (2008) Metformin, sulfonylureas, or other antidiabetes drugs and the risk of lactic acidosis or hypoglycemia : a nested case-control analysis. Diabetes Care, Vol. 31. pp. 2086-2091.
Botomino, Andrea and Bruppacher, Rudolf and Krähenbühl, Stephan and Hersberger, Kurt E.. (2008) Change of body weight and lifestyle of persons at risk for diabetes after screening and counselling in pharmacies. Pharmacy world & science, Vol. 30, H. 3. pp. 222-226.
Brauchli, Y. B. and Jick, S. S. and Curtin, F. and Meier, C. R.. (2008) Association between beta-blockers, other antihypertensive drugs and psoriasis : population-based case-control study. British journal of dermatology, Vol. 158, H. 6. pp. 1299-1307.
Brauchli, Y. B. and Jick, S. S. and Curtin, F. and Meier, C. R.. (2008) Association between use of thiazolidinediones or other oral antidiabetics and psoriasis : a population based case-control study. Journal of the American Academy of Dermatology, Vol. 58, H. 3. pp. 421-429.
Brauchli, Y. B. and Jick, S. S. and Meier, C. R.. (2008) Psoriasis and the risk of incident diabetes mellitus : a population-based study. British journal of dermatology, Vol. 159, H. 6. pp. 1331-1337.
Brauchli, Yolanda B. and Gittermann, Matthias and Michot, Marc and Krähenbühl, Stephan and Gnehm, Hanspeter E.. (2008) A fatal tick bite occurring during the course of tick-borne encephalitis vaccination. Pediatric infectious disease journal, Vol. 27. pp. 363-365.
Brauchli, Yolanda B. and Scholer, André and Schwietert, Martin and Krähenbühl, Stephan. (2008) Undetectable phenytoin serum levels by an automated particle-enhanced turbidimetric inhibition immunoassay in a patient with monoclonal IgM lambda. Clinica chimica acta, Vol. 389, H. 1-2. pp. 174-176.
Drewe, J. and Mihailovic, S. and D'Amato, M. and Beglinger, C.. (2008) Regulation of fat-stimulated neurotensin secretion in healthy subjects. Journal of clinical endocrinology and metabolism, Vol. 93, H. 5. pp. 1964-1970.
Grauwiler, S. B. and Drewe, J. and Scholer, A.. (2008) Sensitivity and specificity of urinary cannabinoid detection with two immunoassays after controlled oral administration of cannabinoids to humans. Therapeutic drug monitoring, Vol. 30, H. 4. pp. 530-535.
Gutmann, H. and Hruz, P. and Zimmermann, C. and Straumann, A. and Terracciano, L. and Hammann, F. and Lehmann, F. and Beglinger, C. and Drewe, J.. (2008) Breast cancer resistance protein and P-glycoprotein expression in patients with newly diagnosed and therapy-refractory ulcerative colitis compared with healthy controls. Digestion, 78 (2-3). pp. 154-162.
Huwyler, J. and Drewe, J. and Krähenbuhl, S.. (2008) Tumor targeting using liposomal antineoplastic drugs. International Journal of Nanomedicine, 3 (1). pp. 21-29.
Kemnitzer, W. and Drewe, J. and Jiang, S. and Zhang, H. and Crogan-Grundy, C. and Labreque, D. and Bubenick, M. and Attardo, G. and Denis, R. and Lamothe, S. and Gourdeau, H. and Tseng, B. and Kasibhatla, S. and Cai, S. X.. (2008) Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions. Journal of medicinal chemistry, Vol. 51, H. 3. pp. 417-423.
Knapp, Andrea Caroline and Todesco, Liliane and Beier, Konstantin and Terracciano, Luigi and Saegesser, Hans and Reichen, Juerg and Kraehenbuehl, Stephan. (2008) Toxicity of valproic acid in mice with decreased plasma and tissue carnitine stores. The Journal of Pharmacology and Experimental Therapeutics, Vol. 324, H. 2. pp. 568-575.
Knapp, Andrea Caroline and Todesco, Liliane and Torok, Michael and Beier, Konstantin and Krähenbühl, Stephan. (2008) Effect of carnitine deprivation on carnitine homeostasis and energy metabolism in mice with systemic carnitine deficiency. Annals of nutrition and metabolism, Vol. 52, No. 2. pp. 136-144.
Kummer, O. and Hammann, F. and Bodmer, M. and Novakova, K. and Krähenbühl, S. and Haschke, M.. (2008) [Drug-induced toxic hepatitis]. Schweizerische Rundschau für Medizin PRAXIS, Vol. 97 , S. 235-239 ; quiz 240-241.
Liechti, Matthias E. and Markou, Athina. (2008) Role of the glutamatergic system in nicotine dependence : implications for the discovery and development of new pharmacological smoking cessation therapies. CNS drugs, Vol. 22, no. 9. pp. 705-724.
Link, Bettina and Haschke, Manuel and Grignaschi, Nathalie and Bodmer, Michael and Aschmann, Yvonne Zysset and Wenk, Markus and Krähenbühl, Stephan. (2008) Pharmacokinetics of intravenous and oral midazolam in plasma and saliva in humans: usefulness of saliva as matrix for CYP3A phenotyping. British journal of clinical pharmacology, 66 (4). pp. 473-484.
Lüde, Saskia and Török, Michael and Dieterle, Sandy and Jäggi, René and Büter, Karin Berger and Krähenbühl, Stephan. (2008) Hepatocellular toxicity of kava leaf and root extracts. Phytomedicine, Vol. 15, H. 1-2. pp. 120-131.
Meier, C. and Kraenzlin, M. E. and Bodmer, M. and Jick, S. S. and Jick, H. and Meier, C. R.. (2008) Use of thiazolidinediones and fracture risk. Archives of internal medicine, Vol. 168. pp. 820-825.
Poller, B. and Gutmann, H. and Krähenbühl, S. and Weksler, B. and Romero, I. and Couraud, P. O. and Tuffin, G. and Drewe, J. and Huwyler, J.. (2008) The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies. Journal of Neurochemistry, Vol. 107, H. 5. pp. 1358-1368.
Todesco, L. and Bur, D. and Brooks, H. and Török, M. and Landmann, L. and Stieger, B. and Krähenbühl, S.. (2008) Pharmacological manipulation of L-carnitine transport into L6 cells with stable overexpression of human OCTN2. Cellular and molecular life sciences, Vol. 65, no. 10. pp. 1596-1608.
Traut, U. and Brügger, L. and Kunz, R. and Pauli-Magnus, C. and Haug, K. and Bucher, H. C. and Koller, M. T.. (2008) Systemic prokinetic pharmacologic treatment for postoperative adynamic ileus following abdominal surgery in adults. The Cochrane database of systematic reviews, Vol. 1 , CD004930.
Vonbach, Priska and Dubied, André and Krähenbühl, Stephan and Beer, Jürg H.. (2008) Evaluation of frequently used drug interaction screening programs. Pharmacy world & science, Vol. 30, H. 4. pp. 367-374.
Vonbach, Priska and Dubied, André and Krähenbühl, Stephan and Beer, Jürg H.. (2008) Prevalence of drug-drug interactions at hospital entry and during hospital stay of patients in internal medicine. European journal of internal medicine, Vol. 19, H. 6. pp. 413-420.
Waldhauser, Katri M. and Brecht, Karin and Hebeisen, S. and Ha, H. R. and Konrad, D. and Bur, Daniel and Krähenbühl, Stephan. (2008) Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues. British journal of pharmacology, 155 (4). pp. 585-595.
Yam, J. and Kreuter, M. and Drewe, J.. (2008) Piper cubeba targets multiple aspects of the androgen-signalling pathway : a potential phytotherapy against prostate cancer growth? Planta medica, Vol. 74. pp. 33-38.
Yam, J. and Schaab, A. and Kreuter, M. and Drewe, J.. (2008) Piper cubeba demonstrates anti-estrogenic and anti-inflammatory properties. Planta medica, Vol. 74. pp. 142-146.
Mühlebach, Stefan F. and Karlaganis, G. and Honegger, U. E.. (2006) Kinetic assessment of persistent halogenated xenobiotics in cell culture models: comparison of mono- and poly-halogenated compounds. Chemosphere, 62 (11). pp. 1838-1845.
Schmid, Andreas Ulrich. Metabolites of ethanol as markers of alcohol abuse : glutathione consumption and methionine kinetics in humans. 2004, Doctoral Thesis, University of Basel, Faculty of Science.
Steger, P. J. and Mühlebach, Stefan F.. (2000) Lipid peroxidation of intravenous lipid emulsions and all-in-one admixtures in total parenteral nutrition bags: the influence of trace elements. JPEN, Journal of parenteral and enteral nutrition, 24 (1). pp. 37-41.
Jondorf, W. R. and Wyss, P. A. and Mühlebach, S. and Bickel, M. H.. (1983) Disposition of 2,2',4,4',5,5'-hexachlorobiphenyl (6-CB) in rats with decreasing adipose tissue mass. II. Effects of restricting food intake before and after 6-CB administration. Drug Metabolism and Disposition, 11 (6). pp. 597-601.
Wyss, P. A. and Mühlebach, S. and Bickel, M. H.. (1982) Pharmacokinetics of 2,2',4,4',5,5'-hexachlorobiphenyl (6-CB) in rats with decreasing adipose tissue mass. I. Effects of restricting food intake two weeks after administration of 6-CB. Drug Metabolism and Disposition, 10 (6). pp. 657-661.