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Minimal dose for severe poisoning and influencing factors in acute human clozapine intoxication : a 13-year retrospective study

Krämer, Isabel and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Krähenbühl, Stephan and Ceschi, Alessandro. (2010) Minimal dose for severe poisoning and influencing factors in acute human clozapine intoxication : a 13-year retrospective study. Clinical neuropharmacology, Vol. 33, H. 5. pp. 230-234.

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Official URL: http://edoc.unibas.ch/dok/A6003757

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Abstract

Clozapine is an atypical antipsychotic drug used in the treatment of resistant schizophrenia. Intoxications with this drug are frequently observed. The aim of the present study was to identify a minimal dose and the dose bearing a 50% risk of developing moderate or severe intoxication symptoms. We also investigated the influence of age, sex, effect of decontamination measures, and pretreatment with clozapine on the severity of poisoning.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Klinische Pharmakologie > Klinische Pharmakologie (Krähenbühl)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Klinische Pharmakologie > Klinische Pharmakologie (Krähenbühl)
UniBasel Contributors:Krähenbühl, Stephan
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Lippincott Williams & Wilkins
ISSN:0362-5664
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:24 May 2013 09:12
Deposited On:26 Apr 2013 06:55

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