Browse by Basel Contributors ID

Yes

Seebacher, W. and Kaiser, M. and Mäser, P. and Saf, R. and Pferschy-Wenzig, E. M. and Weis, R.. (2023) Benzyl- and dibenzyl tetrahydropyridinylidene ammonium salts with antiplasmodial and antitrypanosomal activity. Monatshefte fuÌ�r Chemie, 154. pp. 105-114.

Walz, A. and Duffey, M. and Aljayyoussi, G. and Sax, S. and Leroy, D. and Besson, A. and Burrows, J. N. and Cherkaoui-Rbati, M. H. and Gobeau, N. and Westwood, M.-A. and Siethoff, C. and Gamo, S. and Mäser, P. and Wittlin, S.. (2023) The Parasite Reduction Ratio (PRR) assay version 2: standardized assessment of Plasmodium falciparum viability after antimalarial treatment in vitro. Pharmaceuticals (Basel), 16 (2). p. 163.

Rao, S. P. S. and Gould, M. K. and Noeske, J. and Saldivia, M. and Jumani, R. S. and Ng, P. S. and Rene, O. and Chen, Y. L. and Kaiser, M. and Ritchie, R. and Francisco, A. F. and Johnson, N. and Patra, D. and Cheung, H. and Deniston, C. and Schenk, A. D. and Cortopassi, W. A. and Schmidt, R. S. and Wiedemar, N. and Thomas, B. and Palkar, R. and Ghafar, N. A. and Manoharan, V. and Luu, C. and Gable, J. E. and Wan, K. F. and Myburgh, E. and Mottram, J. C. and Barnes, W. and Walker, J. and Wartchow, C. and Aziz, N. and Osborne, C. and Wagner, J. and Sarko, C. and Kelly, J. M. and Manjunatha, U. H. and Mäser, P. and Jiricek, J. and Lakshminarayana, S. B. and Barrett, M. P. and Diagana, T. T.. (2023) Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380 (6652). pp. 1349-1356.

Sevik Kilicaslan, O. and Cretton, S. and Hausmann, E. and Quirós-Guerrero, L. and Karimou, S. and Kaiser, M. and Mäser, P. and Christen, P. and Cuendet, M.. (2023) Antiprotozoal activity of natural products from Nigerien plants used in folk medicine. Front Pharmacol, 14. p. 1190241.

Beilstein, S. and El Phil, R. and Sahraoui, S. S. and Scapozza, L. and Kaiser, M. and Mäser, P.. (2022) Laboratory selection of trypanosomatid pathogens for drug resistance. Pharmaceuticals (Basel), 15 (2). p. 135.

Bernhard, S. and Kaiser, M. and Burri, C. and Mäser, P.. (2022) Fexinidazole for human African trypanosomiasis, the fruit of a successful public-private partnership. Diseases, 10 (4). p. 90.

Dolensky, J. and Hinteregger, C. and Leitner, A. and Seebacher, W. and Saf, R. and Belaj, F. and Mäser, P. and Kaiser, M. and Weis, R.. (2022) Antiprotozoal activity of azabicyclo-nonanes linked to tetrazole or sulfonamide cores. Molecules, 27 (19). p. 6217.

Koester, D. C. and Marx, V. M. and Williams, S. and Jiricek, J. and Dauphinais, M. and René, O. and Miller, S. L. and Zhang, L. and Patra, D. and Chen, Y. L. and Cheung, H. and Gable, J. and Lakshminarayana, S. B. and Osborne, C. and Galarneau, J. R. and Kulkarni, U. and Richmond, W. and Bretz, A. and Xiao, L. and Supek, F. and Wiesmann, C. and Honnappa, S. and Be, C. and Mäser, P. and Kaiser, M. and Ritchie, R. and Barrett, M. P. and Diagana, T. T. and Sarko, C. and Rao, S. P. S.. (2022) Discovery of novel quinoline-based proteasome inhibitors for Human African Trypanosomiasis (HAT). Journal of medicinal chemistry, 65. 11776−11787.

Mousavi, A. and Foroumadi, P. and Emamgholipour, Z. and Mäser, P. and Kaiser, M. and Foroumadi, A.. (2022) 2-(Nitroaryl)-5-substituted-1,3,4-thiadiazole derivatives with antiprotozoal activities: in vitro and in vivo study. Molecules, 27. p. 5559.

Scheiber, N. and Blaser, G. and Pferschy-Wenzig, E. M. and Kaiser, M. and Mäser, P. and Presser, A.. (2022) Efficient oxidative dearomatisations of substituted phenols using hypervalent iodine (iii) reagents and antiprotozoal evaluation of the resulting cyclohexadienones against T. b. rhodesiense and P. falciparum Strain NF54. Molecules, 27 (19). p. 6559.

Sevik Kilicaslan, O. and Cretton, S. and Quiros-Guerrero, L. and Bella, M. A. and Kaiser, M. and Mäser, P. and Ndongo, J. T. and Cuendet, M.. (2022) Isolation and structural elucidation of compounds from Pleiocarpa bicarpellata and their in vitro antiprotozoal activity. Molecules, 27 (7). p. 2200.

Hermann, T. and Wallner, R. and Dolensky, J. and Seebacher, W. and Pferschy-Wenzig, E. -M. and Kaiser, M. and Mäser, P. and Weis, R.. (2022) New derivatives of the multi-stage active Malaria Box compound MMV030666 and their antiplasmodial potencies. Pharmaceuticals (Basel), 15 (12). p. 1503.

Hinteregger, C. and Dolensky, J. and Seebacher, W. and Saf, R. and Mäser, P. and Kaiser, M. and Weis, R.. (2022) Synthesis and antiprotozoal activity of azabicyclo-nonane pyrimidine hybrids. Molecules, 28. p. 307.

Mäser, P.. (2022) Filariae as organisms. In: Human and animal filariases: Landscape, challenges, and control. Hoboken, New Jersey, pp. 17-32.

Brand, M. and Wang, L. and Agnello, S. and Gazzola, S. and Gall, F. M. and Raguz, L. and Kaiser, M. and Schmidt, R. S. and Ritschl, A. and Jelk, J. and Hemphill, A. and Mäser, P. and Butikofer, P. and Adams, M. and Riedl, R.. (2021) Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action. Angewandte Chemie, 60 (28). pp. 15613-15621.

Boberg, M. and Cal, M. and Kaiser, M. and Jansson-Lofmark, R. and Mäser, P. and Ashton, M.. (2021) Enantiospecific antitrypanosomal in vitro activity of eflornithine. PLoS Negl Trop Dis, 15 (7). e0009583.

Flittner, D. and Kaiser, M. and Mäser, P. and Lopes, N. P. and Schmidt, T. J.. (2021) The alkaloid-enriched fraction of; The alkaloid-enriched fraction of Pachysandra terminalis (Buxaceae) shows prominent activity against Trypanosoma brucei rhodesiensePachysandra terminalis; (Buxaceae) shows prominent activity against; Trypanosoma brucei rhodesiense. Molecules, 26 (3). p. 591.

Fesser, A. and Kaiser, M. and Mäser, P.. (2021) Neue Parameter für die Wirkstofftestung gegen Trypanosoma cruzi. Biospektrum (Heidelb), 27 (2). pp. 168-170.

Cretton, S. and Genta-Jouve, G. and Kaiser, M. and Mäser, P. and Muñoz, O. and Bürgi, T. and Cuendet, M. and Christen, P.. (2021) Hygroline derivatives from Schizanthus tricolor and their anti-trypanosomatid and antiplasmodial activities. Phytochemistry, 192. p. 112957.

Hoffelner, M. H. and Seebacher, W. and Kaiser, M. and Mäser, P. and Pferschy-Wenzig, E. M. and Saf, R. and Belaj, F. and Kretschmer, N. and Alajlani, M. and Brantner, A. and Bauer, R. and Weis, R.. (2021) Unexpected ring‑opening of 2,3‑dihydropyridines. Monatshefte für Chemie, 152. pp. 1347-1359.

Hochegger, P. and Dolensky, J. and Seebacher, W. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2021) 8-amino-6-methoxyquinoline-tetrazole hybrids: Impact of linkers on antiplasmodial activity. Molecules, 26 (18). p. 5530.

Hitz, E. and Wiedemar, N. and Passecker, A. and Graça, B. A. S. and Scheurer, C. and Wittlin, S. and Brancucci, N. M. B. and Vakonakis, I. and Mäser, P. and Voss, T. S.. (2021) The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites. PLoS Biol, 19 (12). e3001483.

Hermann, T. and Hochegger, P. and Dolensky, J. and Seebacher, W. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2021) New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities. Pharmaceuticals (Basel), 14 (5). p. 412.

Hermann, T. and Hochegger, P. and Dolensky, J. and Seebacher, W. and Pferschy-Wenzig, E. M. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2021) Synthesis and structure-activity relationships of new 2-phenoxybenzamides with antiplasmodial activity. Pharmaceuticals (Basel), 14. p. 1109.

Greve, H. L. and Kaiser, M. and Mäser, P. and Schmidt, T. J.. (2021) Boswellic acids show in vitro activity against Leishmania donovani. Molecules, 26 (12). p. 3651.

Llurba Montesino, N. and Kaiser, M. and Mäser, P. and Schmidt, T. J.. (2021) Nucleic acid amplification techniques for the detection of Schistosoma mansoni infection in humans and the intermediate snail host: a structured review and meta-analysis of diagnostic accuracy. Molecules, 26 (11). p. 3226.

Mahmoud, A. B. and Abd Algaffar, S. and van de Sande, W. and Khalid, S. and Kaiser, M. and Mäser, P.. (2021) Niclosamide is active in vitro against mycetoma pathogens. Molecules, 26 (13). p. 4005.

Rocha-Hasler, M. and de Oliveira, G. M. and da Gama, A. N. and Fiuza, L. F. A. and Fesser, A. F. and Cal, M. and Rocchetti, R. and Peres, R. B. and Guan, X. L. and Kaiser, M. and Soeiro, M. N. C. and Mäser, P.. (2021) Combination with tomatidine improves the potency of posaconazole against Trypanosoma cruzi. Front Cell Infect Microbiol, 11. p. 617917.

Petritsch, M. and Seebacher, W. and Mohsin, N. U. and Dolensky, J. and Hochegger, P. and Kaiser, M. and Mäser, P. and Belaj, F. and Saf, R. and Kretschmer, N. and Alajlani, M. and Brantner, A. and Bauer, R. and Schuhly, W. and Weis, R.. (2021) Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. Eur J Med Chem, 210. p. 112969.

Seebacher, W. and Mohsin, N. U. A. and Dolensky, J. and Hochegger, P. and Kaiser, M. and Mäser, P. and Saf, R. and Schuster, D. and Temml, V. and Weis, R.. (2021) Modifications and hybrids of 1,2,3,4‑tetrahydropyridinium salts and their antiprotozoal potencies. Monatshefte fuÌ�r Chemie, 152. pp. 1347-1359.

Szabó, L. U. and Kaiser, M. and Mäser, P. and Schmidt, T. J.. (2021) Identification of antiprotozoal compounds from Buxus sempervirens L. by PLS-prediction. Molecules, 26 (20). p. 6181.

Szabó, L. U. and Kaiser, M. and Mäser, P. and Schmidt, T. J.. (2021) Antiprotozoal Nor-triterpene alkaloids from Buxus sempervirens L. Antibiotics (Basel), 10 (6). p. 696.

Zeelen, J. and van Straaten, M. and Verdi, J. and Hempelmann, A. and Hashemi, H. and Perez, K. and Jeffrey, P. D. and Hälg, S. and Wiedemar, N. and Mäser, P. and Papavasiliou, F. N. and Stebbins, C. E.. (2021) Structure of trypanosome coat protein VSGsur and function in suramin resistance. Nat Microbiol, 6 (3). pp. 392-400.

Wittlin, S. and Mäser, P.. (2021) From magic bullet to magic bomb: reductive bioactivation of antiparasitic agents. ACS Infect Dis, 7 (10). pp. 2777-2786.

Barth-Jaeggi, T. and Mäser, P.. (2021) Leishmaniasis in Europe and Central Asia: epidemiology, impact of habitat and lifestyle changes, HIV coinfection. In: Neglected tropical diseases - Europe and Central Asia. Cham, pp. 83-100.

Vahekeni, Nina and Neto, Pedro Menezes and Kayimbo, Malilo Kaluiji and Mäser, Pascal and Josenando, Théophile and da Costa, Esperança and Falquet, Jacques and Van Eeuwijk, Piet. (2020) Use of herbal remedies in the management of sleeping sickness in four northern provinces of Angola. Journal of Ethnopharmacology. p. 20.

Dawidowski, Maciej and Kalel, Vishal C. and Napolitano, Valeria and Fino, Roberto and Schorpp, Kenji and Emmanouilidis, Leonidas and Lenhart, Dominik and Ostertag, Michael and Kaiser, Marcel and Kolonko, Marta and Tippler, Bettina and Schliebs, Wolfgang and Dubin, Grzegorz and Mäser, Pascal and Tetko, Igor V. and Hadian, Kamyar and Plettenburg, Oliver and Erdmann, Ralf and Sattler, Michael and Popowicz, Grzegorz M.. (2020) Structure-activity relationship in pyrazolo[4,3-c]pyridines, first inhibitors of PEX14-PEX5 protein-protein interaction with trypanocidal activity. Journal of medicinal chemistry, 63 (2). pp. 847-879.

Rao, Srinivasa P. S. and Lakshminarayana, Suresh B. and Jiricek, Jan and Kaiser, Marcel and Ritchie, Ryan and Myburgh, Elmarie and Supek, Frantisek and Tuntland, Tove and Nagle, Advait and Molteni, Valentina and Mäser, Pascal and Mottram, Jeremy C. and Barrett, Michael P. and Diagana, Thierry T.. (2020) Anti-trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of african trypanosomiasis. Tropical medicine and infectious disease, 5. p. 28.

Wiedemar, Natalie and Hauser, Dennis A. and Mäser, Pascal. (2020) 100 years of Suramin. Antimicrobial agents and chemotherapy, 64 (3). e01168-19.

Mahmoud, Abdelhalim Babiker and Danton, Ombeline and Kaiser, Marcel and Han, Sohee and Moreno, Aitor and Abd Algaffar, Shereen and Khalid, Sami and Oh, Won Keun and Hamburger, Matthias and Mäser, Pascal. (2020) Lignans, amides, and saponins from Haplophyllum tuberculatum and their antiprotozoal activity. Molecules, 25 (12). p. 2825.

Mahmoud, Abdelhalim Babiker and Mäser, Pascal and Kaiser, Marcel and Hamburger, Matthias and Khalid, Sami. (2020) Mining sudanese medicinal plants for antiprotozoal agents. Frontiers in pharmacology, 11. p. 865.

Fesser, Anna F. and Braissant, Olivier and Olmo, Francisco and Kelly, John M. and Mäser, Pascal and Kaiser, Marcel. (2020) Non-invasive monitoring of drug action: a new live in vitro assay design for Chagas' disease drug discovery. PLoS Neglected Tropical Diseases, 14 (7). e0008487.

Mahmoud, Abdelhalim Babiker and Danton, Ombeline and Kaiser, Marcel and Khalid, Sami and Hamburger, Matthias and Mäser, Pascal. (2020) HPLC-based activity profiling for antiprotozoal compounds in Croton gratissimus and Cuscuta hyalina. Frontiers in Pharmacology, 11. p. 1246.

Cretton, S. and Kaiser, M. and Karimou, S. and Ebrahimi, S. N. and Mäser, P. and Cuendet, M. and Christen, P.. (2020) Pyridine-4(1H)-one alkaloids from Waltheria indica as antitrypanosomatid agents. Journal of natural products, 83 (11). pp. 3363-3371.

Hoffelner, M. and Hassan, U. and Seebacher, W. and Dolensky, J. and Hochegger, P. and Kaiser, M. and Mäser, P. and Saf, R. and Weis, R.. (2020) New 2‑aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities. Monatshefte für Chemie, 151. pp. 1375-1385.

Saccoliti, Francesco and Madia, Valentina Noemi and Tudino, Valeria and De Leo, Alessandro and Pescatori, Luca and Messore, Antonella and De Vita, Daniela and Scipione, Luigi and Brun, Reto and Kaiser, Marcel and Mäser, Pascal and Calvet Alvarez, Claudia Magalhaes and Jennings, Gareth K. and Podust, Larissa M. and Pepe, Giacomo and Cirilli, Roberto and Faggi, Cristina and Di Marco, Annalise and Battista, Maria Rosaria and Summa, Vincenzo and Costi, Roberta and Di Santo, Roberto. (2019) Design, synthesis, and biological evaluation of new 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives as antiprotozoal agents. Journal of Medicinal Chemistry, 62 (3). pp. 1330-1347.

Rao, Srinivasa P. S. and Barrett, Michael P. and Dranoff, Glenn and Faraday, Christopher J. and Gimpelewicz, Claudio R. and Hailu, Asrat and Jones, Catherine L. and Kelly, John M. and Lazdins-Helds, Janis K. and Mäser, Pascal and Mengel, Jose and Mottram, Jeremy C. and Mowbray, Charles E. and Sacks, David L. and Scott, Phillip and Späth, Gerald F. and Tarleton, Rick L. and Spector, Jonathan M. and Diagana, Thierry T.. (2019) Drug discovery for kinetoplastid diseases : future directions. ACS infectious diseases, 5 (2). pp. 152-157.

Hochegger, Patrick and Faist, Johanna and Seebacher, Werner and Saf, Robert and Mäser, Pascal and Kaiser, Marcel and Weis, Robert. (2019) Synthesis and structure-activity relationships for new 6-fluoroquinoline derivatives with antiplasmodial activity. Bioorganic & medicinal chemistry, 27 (10). pp. 2052-2065.

Baragaña, Beatriz and Forte, Barbara and Choi, Ryan and Nakazawa Hewitt, Stephen and Bueren-Calabuig, Juan A. and Pisco, João Pedro and Peet, Caroline and Dranow, David M. and Robinson, David A. and Jansen, Chimed and Norcross, Neil R. and Vinayak, Sumiti and Anderson, Mark and Brooks, Carrie F. and Cooper, Caitlin A. and Damerow, Sebastian and Delves, Michael and Dowers, Karen and Duffy, James and Edwards, Thomas E. and Hallyburton, Irene and Horst, Benjamin G. and Hulverson, Matthew A. and Ferguson, Liam and Jiménez-Díaz, María Belén and Jumani, Rajiv S. and Lorimer, Donald D. and Love, Melissa S. and Maher, Steven and Matthews, Holly and McNamara, Case W. and Miller, Peter and O'Neill, Sandra and Ojo, Kayode K. and Osuna-Cabello, Maria and Pinto, Erika and Post, John and Riley, Jennifer and Rottmann, Matthias and Sanz, Laura M. and Scullion, Paul and Sharma, Arvind and Shepherd, Sharon M. and Shishikura, Yoko and Simeons, Frederick R. C. and Stebbins, Erin E. and Stojanovski, Laste and Straschil, Ursula and Tamaki, Fabio K. and Tamjar, Jevgenia and Torrie, Leah S. and Vantaux, Amélie and Witkowski, Benoît and Wittlin, Sergio and Yogavel, Manickam and Zuccotto, Fabio and Angulo-Barturen, Iñigo and Sinden, Robert and Baum, Jake and Gamo, Francisco-Javier and Mäser, Pascal and Kyle, Dennis E. and Winzeler, Elizabeth A. and Myler, Peter J. and Wyatt, Paul G. and Floyd, David and Matthews, David and Sharma, Amit and Striepen, Boris and Huston, Christopher D. and Gray, David W. and Fairlamb, Alan H. and Pisliakov, Andrei V. and Walpole, Chris and Read, Kevin D. and Van Voorhis, Wesley C. and Gilbert, Ian H.. (2019) Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America, 116 (14). pp. 7015-7020.

Mohsin, N. U. A. and Seebacher, W. and Hochegger, P. and Faist, J. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2019) Synthesis of new 1-benzyl tetrahydropyridin-4-ylidene piperidinium salts and their antiplasmodial and antitrypanosomal activities. Medicinal chemistry research, 28 (5). pp. 742-753.

Hochegger, Patrick and Faist, Johanna and Seebacher, Werner and Saf, Robert and Mäser, Pascal and Kaiser, Marcel and Weis, Robert. (2019) Antiprotozoal activities of tetrazole-quinolines with aminopiperidine linker. Medicinal chemistry (Shariqah (United Arab Emirates)), 15 (4). pp. 409-416.

Mäser, P.. (2019) Parasiten machen Geschichte. In: Gespräche im Garten: Kultur - Natur - Gutes Leben: Tusculum auf Mapprach. Basel, pp. 127-131.

Vu Van , T. and Pham-Duc , P. and Winkler, M. S. and Zurbrügg, C. and Zinsstag, J. and Tran, B. H. and Nguyen-Viet , H.. (2019) New derivatives of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities. Monatshefte für Chemie, 150 (11). pp. 1959-1972.

Walz, A. and Leroy, D. and Andenmatten, N. and Mäser, P. and Wittlin, S.. (2019) Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay. Malaria journal, 18. p. 427.

Jourdan, Joëlle and Walz, Annabelle and Matile, Hugues and Schmidt, Alexander and Wu, Jianbo and Wang, Xiaofang and Dong, Yuxiang and Vennerstrom, Jonathan L. and Schmidt, Remo S. and Wittlin, Sergio and Mäser, Pascal. (2019) Stochastic protein alkylation by antimalarial peroxides. ACS Infectious Diseases, 5 (12). pp. 2067-2075.

Wiedemar, Natalie and Zwyer, Michaela and Zoltner, Martin and Cal, Monica and Field, Mark C. and Mäser, Pascal. (2019) Expression of a specific variant surface glycoprotein has a major impact on suramin sensitivity and endocytosis in Trypanosoma brucei. FASEB bioAdvances, 1 (10). pp. 595-608.

Wiedemar, Natalie and Graf, Fabrice E. and Zwyer, Michaela and Ndomba, Emiliana and Kunz Renggli, Christina and Cal, Monica and Schmidt, Remo S. and Wenzler, Tanja and Mäser, Pascal. (2018) Beyond immune escape: a variant surface glycoprotein causes suramin resistance in Trypanosoma brucei. Molecular Microbiology, 107 (1). pp. 57-67.

Mohsin, N. U. A. and Seebacher, W. and Faist, J. and Hochegger, P. and Kaiser, M. and Mäser, P. and Saf, R. and Weis, R.. (2018) The antiplasmodial and antitrypanosomal activities of novel piperazine derivatives of 3-azabicyclo[3.2.2]nonanes. Monatshefte für Chemie, 149 (1). pp. 99-109.

Subramaniam, Suvitha and Schmid, Christoph D. and Guan, Xue Li and Mäser, Pascal. (2018) Using yeast synthetic lethality to inform drug combination for Malaria. Antimicrobial Agents and Chemotherapy, 62 (4). e01533-17.

Mohsin, N. U. A. and Seebacher, W. and Faist, J. and Kretschmer, N. and Bauer, R. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2018) Modifications on tetrahydropyridin-4-ylidene ammonium salts and their antiprotozoal activities. Monatshefte für Chemie, 149 (4). pp. 801-812.

Grogg, Marcel and Hilvert, Donald and Ebert, Marc-Olivier and Beck, Albert K. and Seebach, Dieter and Kurth, Felix and Dittrich, Petra S. and Sparr, Christof and Wittlin, Sergio and Rottmann, Matthias and Mäser, Pascal. (2018) Cell penetration, herbicidal activity, and in-vivo-toxicity of oligo-arginine derivatives and of novel guanidinium-rich compounds derived from the biopolymer cyanophycin. Helvetica Chimica Acta, 101 (10). e1800112.

Kalel, Vishal C. and Mäser, Pascal and Sattler, Michael and Erdmann, Ralf and Popowicz, Grzegorz M.. (2018) Come, sweet death : targeting glycosomal protein import for antitrypanosomal drug development. Current Opinion in Microbiology, 46. pp. 116-122.

Mäser, Pascal. (2018) Host-microbe interactions: Parasitology Vol 46. Current opinion in microbiology, 46. pp. 6-8.

Oufir, M. Gillingwater and K. Hamburger, M. Roditi and I. Brun, R. Mäser and P. Wenzler, T.. (2018) Pharmacokinetic profiles reconcile in vitro and in vivo activities of novel trypanocidal compounds. Matters. 07000009.

Schmidt, Remo S. and Macêdo, Juan P. and Steinmann, Michael E. and Salgado, Amaia González and Bütikofer, Peter and Sigel, Erwin and Rentsch, Doris and Mäser, Pascal. (2018) Transporters of Trypanosoma brucei : phylogeny, physiology, pharmacology. The FEBS journal, 285 (6). pp. 1012-1023.

Gysin, M. and Braissant, O. and Gillingwater, K. and Brun, R. and Mäser, P. and Wenzler, T.. (2018) Isothermal microcalorimetry - a quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time. International journal for parasitology. Drugs and drug resistance, 8 (2). pp. 159-164.

Saccoliti, Francesco and Madia, Valentina Noemi and Tudino, Valeria and De Leo, Alessandro and Pescatori, Luca and Messore, Antonella and De Vita, Daniela and Scipione, Luigi and Brun, Reto and Kaiser, Marcel and Mäser, Pascal and Calvet, Claudia Magalhaes and Jennings, Gareth K. and Podust, Larissa M. and Costi, Roberta and Di Santo, Roberto. (2018) Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents. European journal of medicinal chemistry, 156. pp. 53-60.

Mathieu, Christoph and Macêdo, Juan P. and Hürlimann, Daniel and Wirdnam, Corina and Haindrich, Alexander C. and Suter Grotemeyer, Marianne and González-Salgado, Amaia and Schmidt, Remo S. and Inbar, Ehud and Mäser, Pascal and Bütikofer, Peter and Zilberstein, Dan and Rentsch, Doris. (2017) Arginine and lysine transporters are essential for Trypanosoma brucei. PLoS ONE, 12. e0168775.

Faist, Johanna and Hinteregger, Clemens and Seebacher, Werner and Saf, Robert and Mäser, Pascal and Kaiser, Marcel and Weis, Robert. (2017) New derivatives of 7-chloroquinolin-4-amine with antiprotozoal activity. Bioorganic & medicinal chemistry, 25 (3). pp. 941-948.

Baumgärtner, Fabian and Jourdan, Joëlle and Scheurer, Christian and Blasco, Benjamin and Campo, Brice and Mäser, Pascal and Wittlin, Sergio. (2017) In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate. Malaria journal, 16. p. 45.

Dawidowski, M. and Emmanouilidis, L. and Kalel, V. C. and Tripsianes, K. and Schorpp, K. and Hadian, K. and Kaiser, M. and Mäser, P. and Kolonko, M. and Tanghe, S. and Rodriguez, A. and Schliebs, W. and Erdmann, R. and Sattler, M. and Popowicz, G. M.. (2017) Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites. Science, 355 (6332). pp. 1416-1420.

Jeacock, Laura and Baker, Nicola and Wiedemar, Natalie and Mäser, Pascal and Horn, David. (2017) Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity. PLoS Pathogens, 13 (3). e1006307.

Steinmann, Michael E. and Schmidt, Remo S. and Bütikofer, Peter and Mäser, Pascal and Sigel, Erwin. (2017) TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes. Scientific Reports, 7 (1). p. 656.

Seebacher, W. and Belaj, F. and Faist, J. and Saf, R. and Bucar, F. and Turek, I. and Branter, A. and Alajlani, M. and Kaiser, M. and Mäser, P. and Weis, R.. (2017) Synthesis of new pyrido-benzodiazepine salts and their antimicrobial activities. Monatshefte für Chemie, 148 (2). pp. 263-274.

Hochegger, Patrick and Faist, Johanna and Seebacher, Werner and Saf, Robert and Mäser, Pascal and Kaiser, Marcel and Weis, Robert. (2017) New derivatives of quinoline-4-carboxylic acid with antiplasmodial activity. Bioorganic & medicinal chemistry, 25 (7). pp. 2251-2259.

Mohsin, Noor-Ul-Amin and Seebacher, Werner and Faist, Johanna and Hochegger, Patrick and Kaiser, Marcel and Mäser, Pascal and Belaj, Ferdinand and Saf, Robert and Kretschmer, Nadine and Alajlani, Muaaz and Turek, Ivana and Brantner, Adelheid and Bauer, Rudolf and Bucar, Franz and Weis, Robert. (2017) Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. European journal of medicinal chemistry, 143. pp. 97-106.

Mäser, Pascal. (2017) Cherchez l'electron. Molecular microbiology, 106 (2). pp. 183-185.

Steinmann, Michael E. and Schmidt, Remo S. and Macêdo, Juan P. and Kunz Renggli, Christina and Bütikofer, Peter and Rentsch, Doris and Mäser, Pascal and Sigel, Erwin. (2017) Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei. PLoS ONE, 12 (12). e0188219.

Guan, Xue Li and Mäser, Pascal. (2017) Comparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries. Scientific reports, 7. p. 13617.

Jourdan, Joëlle and Hugues, Matile and Reift, Ellen and Biehlmaier, Oliver and Dong, Yuxiang and Wang, Xiaofang and Mäser, Pascal and Vennerstrom, Jonathan and Wittlin, Sergio. (2016) Monoclonal antibodies that recognize the alkylation signature of antimalarial ozonides OZ277 (Arterolane) and OZ439 ( Artefenomel). ACS infectious diseases, 2 (1). pp. 54-61.

Wenzler, Tanja and Schumann Burkard, Gabriela and S. Schmidt, Remo and Mäser, Pascal and Bergner, Andreas and Roditi, Isabel and Brun, Reto. (2016) A new approach to chemotherapy : drug-induced differentiation kills African trypanosomes. Scientific Reports, 6. p. 22451.

Wang, Tai and Mäser, Pascal and Picard, Didier. (2016) Inhibition of Plasmodium falciparum Hsp90 contributes to the antimalarial activities of aminoalcohol-carbazoles. Journal of Medicinal Chemistry, 59 (13). pp. 6344-6352.

Graf, Fabrice E. and Ludin, Philipp and Arquint, Christian and Schmidt, Remo S. and Schaub, Nadia and Kunz Renggli, Christina and Munday, Jane C. and Krezdorn, Jessica and Baker, Nicola and Horn, David and Balmer, Oliver and Caccone, Adalgisa and de Koning, Harry P. and Mäser, Pascal. (2016) Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense. Cellular and molecular life sciences, 73 (17). pp. 3387-3400.

Shameer, Sanu and Logan-Klumpler, Flora J. and Vinson, Florence and Cottret, Ludovic and Merlet, Benjamin and Achcar, Fiona and Boshart, Michael and Berriman, Matthew and Breitling, Rainer and Bringaud, Frédéric and Bütikofer, Peter and Cattanach, Amy M. and Bannerman-Chukualim, Bridget and Creek, Darren J. and Crouch, Kathryn and de Koning, Harry P. and Denise, Hubert and Ebikeme, Charles and Fairlamb, Alan H. and Ferguson, Michael A. J. and Ginger, Michael L. and Hertz-Fowler, Christiane and Kerkhoven, Eduard J. and Mäser, Pascal and Michels, Paul A. M. and Nayak, Archana and Nes, David W. and Nolan, Derek P. and Olsen, Christian and Silva-Franco, Fatima and Smith, Terry K. and Taylor, Martin C. and Tielens, Aloysius G. M. and Urbaniak, Michael D. and van Hellemond, Jaap J. and Vincent, Isabel M. and Wilkinson, Shane R. and Wyllie, Susan and Opperdoes, Fred R. and Barrett, Michael P. and Jourdan, Fabien. (2015) TrypanoCyc : a community-led biochemical pathways database for Trypanosoma brucei. Nucleic Acids Research, 43 (D1). D637-D644.

de Macêdo, Juan P. and Schumann Burkard, Gabriela and Niemann, Moritz and Barrett, Michael P. and Vial, Henri and Mäser, Pascal and Roditi, Isabel and Schneider, André and Bütikofer, Peter. (2015) An atypical mitochondrial carrier that mediates drug action in Trypanosoma brucei. PLoS Pathogens, Vol. 11, H. 5 , e1004875.

Witschel, Matthias C. and Rottmann, Matthias and Schwab, Anatol and Leartsakulpanich, Ubolsree and Chitnumsub, Penchit and Seet, Michael and Tonazzi, Sandro and Schwertz, Geoffrey and Stelzer, Frank and Mietzner, Thomas and McNamara, Case and Thater, Frank and Freymond, Céline and Jaruwat, Aritsara and Pinthong, Chatchadaporn and Riangrungroj, Pinpunya and Oufir, Mouhssin and Hamburger, Matthias and Mäser, Pascal and Sanz-Alonso, Laura M. and Charman, Susan and Wittlin, Sergio and Yuthavong, Yongyuth and Chaiyen, Pimchai and Diederich, François. (2015) Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT) : co-crystal structures of pyrazolopyrans with potent blood-and liver-stage activities. Journal of Medicinal Chemistry, 58 (7). pp. 3117-3130.

Graf, Fabrice E. and Baker, Nicola and Munday, Jane C. and de Koning, Harry P. and Horn, David and Mäser, Pascal. (2015) Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates. International journal for parasitology. Drugs and drug resistance, Vol. 5, H. 2. pp. 65-68.

Kaiser, Marcel and Mäser, Pascal and Tadoori, Leela Pavan and Ioset, Jean-Robert and Brun, Reto. (2015) Antiprotozoal activity profiling of approved drugs : a starting point toward drug repositioning. PLoS ONE, Vol. 10, H. 8 , e0135556.

Steinmann, Michael E. and González-Salgado, Amaia and Bütikofer, Peter and Mäser, Pascal and Sigel, Erwin. (2015) A heteromeric potassium channel involved in the modulation of the plasma membrane potential is essential for the survival of African trypanosomes. The FASEB journal, Vol. 29, H. 8. pp. 3228-3237.

Munday, Jane C. and Eze, Anthonius A. and Baker, Nicola and Glover, Lucy and Clucas, Caroline and Aguinaga Andrés, David and Natto, Manal J. and Teka, Ibrahim A. and McDonald, Jennifer and Lee, Rebecca S. and Graf, Fabrice E. and Ludin, Philipp and Burchmore, Richard J. S. and Turner, C. Michael R. and Tait, Andy and MacLeod, Annette and Mäser, Pascal and Barrett, Michael P. and Horn, David and De Koning, Harry P.. (2014) Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. The journal of antimicrobial chemotherapy, Vol. 69, H. 3. pp. 651-663.

Wang, Tai and Bisson, William H. and Mäser, Pascal and Scapozza, Leonardo and Picard, Didier. (2014) Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors. Journal of medicinal chemistry, 57 (6). pp. 2524-2535.

Lüscher, Alexandra and Lamprea-Burgunder, Estelle and Graf, Fabrice E. and de Koning, Harry P. and Mäser, Pascal. (2014) Trypanosoma brucei adenine-phosphoribosyltransferases mediate adenine salvage and aminopurinol susceptibility but not adenine toxicity. International journal for parasitology : drugs and drug resistance, Vol. 4, H. 1. pp. 55-63.

Fügi, Matthias A. and Gunasekera, Kapila and Ochsenreiter, Torsten and Guan, Xueli and Wenk, Markus R. and Mäser, Pascal. (2014) Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack. Journal of Lipid Research, 55 (5). pp. 929-938.

Mathieu, Christoph and Salgado, Amaia González and Wirdnam, Corina and Meier, Stefan and Grotemeyer, Marianne Suter and Inbar, Ehud and Mäser, Pascal and Zilberstein, Dan and Sigel, Erwin and Bütikofer, Peter and Rentsch, Doris. (2014) Trypanosoma brucei eflornithine transporter AAT6 is a low-affinity low-selective transporter for neutral amino acids. Biochemical journal, Vol. 463, Pt. 1. pp. 9-18.

Sistrom, Mark and Evans, Benjamin and Bjornson, Robert and Gibson, Wendy and Balmer, Oliver and Mäser, Pascal and Aksoy, Serap and Caccone, Adalgisa. (2014) Comparative genomics reveals multiple genetic backgrounds of human pathogenicity in the Trypanosoma brucei complex. Genome biology and evolution, Vol. 6, H. 10. pp. 2811-2819.

Fügi, Matthias A. and Kaiser, Marcel and Tanner, Marcel and Schneiter, Roger and Mäser, Pascal and Guan, Xue Li. (2014) Match-making for posaconazole through systems thinking. Trends in parasitology, Vol. 31, H. 2. pp. 46-51.

Ali, J. A. M. and Creek, D. J. and Burgess, K. and Allison, H. C. and Field, M. C. and Mäser, P. and de Koning, H. P.. (2013) Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines. Molecular pharmacology : an international journal, Vol. 83, H. 2. pp. 439-453.

Baker, Nicola and de Koning, Harry P. and Mäser, Pascal and Horn, David. (2013) Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story. Trends in parasitology, Vol. 29, H. 3. pp. 110-118.

Graf, Fabrice E. and Ludin, Philipp and Wenzler, Tanja and Kaiser, Marcel and Brun, Reto and Pyana, Patient Pati and Büscher, Philippe and de Koning, Harry P. and Horn, David and Mäser, Pascal. (2013) Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol. PLoS neglected tropical diseases, Vol. 7, H. 10 , e2475.

Greganova, Eva and Steinmann, Michael and Mäser, Pascal and Fankhauser, Niklaus. (2013) In silico ionomics segregates parasitic from free-living eukaryotes. Genome biology and evolution, Vol. 5, H. 10. pp. 1902-1909.

Macêdo, Juan P. and Schmidt, Remo S. and Mäser, Pascal and Rentsch, Doris and Vial, Henri J. and Sigel, Erwin and Bütikofer, Peter. (2013) Characterization of choline uptake in Trypanosoma brucei procyclic and bloodstream forms. Molecular & biochemical parasitology, Vol. 190, H. 1. pp. 16-22.

Mäser, P. and Wittlin, S. and Rottmann, M. and Wenzler, T. and Kaiser, M. and Brun, R.. (2012) Antiparasitic agents : new drugs on the horizon. Current opinion in pharmacology, Vol. 12, H. 5. pp. 562-566.

Ludin, Philipp and Woodcroft, Ben and Ralph, Stuart A. and Maeser, Pascal. (2012) In silicio prediction of antimalarial drug target candidates. International journal for parasitology: drugs and drug resistance, Vol. 2. pp. 191-199.

Gonzalez-Salgado, A. and Steinmann, M. E. and Greganova, E. and Rauch, M. and Mäser, P. and Sigel, E. and Bütikofer, P.. (2012) myo-inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei. Journal of biological chemistry, Vol. 287, H. 16. pp. 13313-13323.

Godel, C. and Kumar, S. and Koutsovoulos, G. and Ludin, P. and Nilsson, D. and Comandatore, F. and Wrobel, N. and Thompson, M. and Schmid, C. D. and Goto, S. and Bringaud, F. and Wolstenholme, A. and Bandi, C. and Epe, C. and Kaminsky, R. and Blaxter, M. and Mäser, P.. (2012) The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets. The FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, H. 11. pp. 4650-4661.

Oehring, S. C. and Woodcroft, B. J. and Moes, S. and Wetzel, J. and Dietz, O. and Pulfer, A. and Dekiwadia, C. and Maeser, P. and Flueck, C. and Witmer, K. and Brancucci, N. M. and Niederwieser, I. and Jenoe, P. and Ralph, S. A. and Voss, Till S.. (2012) Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Genome biology, Vol. 13, H. 11 , R108.

Teka, I. A. and Kazibwe, A. J. N. and El-Sabbagh N., and Al-Salabi M. I., and Ward, C. P. and Eze, A. A. and Munday, J. C. and Mäser, P. and Matovu, E. and Barrett, M. P. and de Koning H. P., . (2011) The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes. Molecular pharmacology : an international journal, Vol. 80, H. 1. pp. 110-116.

Lamprea-Burgunder, E. and Ludin, P. and Mäser, P.. (2011) Species-specific typing of DNA based on palindrome frequency patterns. DNA research, 18 (2). pp. 117-124.

Ludin, P. and Nilsson, D. and Mäser, P.. (2011) Genome-wide identification of molecular mimicry candidates in parasites. PLoS ONE, 6 (3). e17546.

Rufener, L. and Keiser, J. and Kaminsky, R. and Mäser, P. and Nilsson, D.. (2010) Phylogenomics of ligand-gated ion channels predicts monepantel effect. PLoS Pathogens, Vol. 6, H. 9 , e1001091.

Mosimann, M. and Goshima, S. and Wenzler, T. and Luscher, A. and Uozumi, N. and Mäser, P.. (2010) A Trk/HKT-type K+ transporter from Trypanosoma brucei. Eukaryotic Cell, Vol. 9, H. 4. pp. 539-546.

Rufener, L. and Baur, R. and Kaminsky, R. and Mäser, P. and Sigel, E.. (2010) Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus. Molecular pharmacology : an international journal, Vol. 78, H. 5. pp. 895-902.

Nerima, B. and Nilsson, D. and Mäser, P.. (2010) Comparative genomics of metabolic networks of free-living and parasitic eukaryotes. BMC Genomics, Vol. 11 , 217.

Kuettel, S. and Mosimann, M. and Mäser, P. and Kaiser, M. and Brun, R. and Scapozza, L. and Perozzo, R.. (2009) Adenosine kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics. PLoS Neglected Tropical Diseases, Vol. 3, H. 8 , e506.

Maina, Naomi and Maina, Kagira Joseph and Mäser, Pascal and Brun, Reto. (2007) Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate. Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin = revue des sciences tropicales et de médecine tropicale = review of tropical science and tropical medicine, 104 (2-3). pp. 84-90.

Bernhard, Sonja C. and Nerima, Barbara and Mäser, Pascal and Brun, Reto. (2007) Melarsoprol- and pentamidine-resistant Trypanosoma brucei rhodesiense populations and their cross-resistance. International journal for parasitology, Vol. 37, H. 13. pp. 1443-1448.

Mäser, Pascal and Grether-Bühler, Yvonne and Kaminsky, Ronald and Brun, Reto. (2002) An anti-contamination cocktail for the in vitro isolation and cultivation of parasitic protozoa. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 88, H. 2. pp. 172-174.