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2011

Götz, Jürgen and Eckert, Anne and Matamales, Miriam and Ittner, Lars M. and Liu, Xin. (2011) Modes of Aβ toxicity in Alzheimer's disease. Cellular and Molecular Life Sciences, Vol. 68, no. 20. S. 3359-3375.

Pagani, Lucia and Schmitt, Karen and Meier, Fides and Izakovic, Jan and Roemer, Konstanze and Viola, Antoine and Cajochen, Christian and Wirz-Justice, Anna and Brown, Steven A. and Eckert, Anne. (2011) Serum factors in older individuals change cellular clock properties. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 17. S. 7218-7223.

Brown, Steven A. and Pagani, Lucia and Cajochen, Christian and Eckert, Anne. (2011) Systemic and cellular reflections on ageing and the circadian oscillator : a mini-review. Gerontology, 57 (5). pp. 427-434.

Lim, Yun-An and Grimm, Amandine and Giese, Maria and Mensah-Nyagan, Ayikoe Guy and Villafranca, J. Ernest and Ittner, Lars M. and Eckert, Anne and Götz, Jürgen. (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-?-mediated deregulation of estradiol. PLoS one, Vol. 6, H. 12 , e28887.

Pagani, Lucia and Eckert, Anne. (2011) Amyloid-Beta interaction with mitochondria. International journal of Alzheimer's disease, Vol. 2011 , 925050.

Brown, Steven A. and Schmitt, Karen and Eckert, Anne. (2011) Aging and circadian disruption : causes and effects. Aging, Vol. 3, H. 8. S. 813-817.

Eckert, Anne and Schmitt, Karen and Götz, Jürgen. (2011) Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity. Alzheimer’s research & therapy, Vol. 3, H. 2. S. 15.

Strosznajder, Joanna B. and Cieslik, Magdalena and Cakala, Magdalena and Jesko, Henryk and Eckert, Anne and Strosznajder, Robert P.. (2011) Lipoxygenases and poly(ADP-ribose) polymerase in amyloid beta cytotoxicity. Neurochemical research, Vol. 36, H. 5. S. 839-848.

Yanagisawa, Katsuhiko and Fantini, Jacques and Chakrabartty, Avijit and Eckert, Anne. (2011) Aβ behavior on neuronal membranes : : aggregation and toxicities. International journal of Alzheimer's disease, Vol. 2011 , 286536.

Kulic, Luka and Wollmer, M. Axel and Rhein, Virginie and Pagani, Lucia and Kuehnle, Katrin and Cattepoel, Susann and Tracy, Jay and Eckert, Anne and Nitsch, Roger M.. (2011) Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration. Neurobiology of aging, Vol. 32, H. 10. S. 1827-1838.

2010

Schaeffer, Véronique and Meyer, Laurence and Patte-Mensah, Christine and Eckert, Anne and Mensah-Nyagan, Ayikoe G.. (2010) Sciatic nerve injury induces apoptosis of dorsal root ganglion satellite glial cells and selectively modifies neurosteroidogenesis in sensory neurons. Glia, Vol. 58, No. 2. S. 169-180.

Rhein, Virginie and Giese, Maria and Baysang, Ginette and Meier, Fides and Rao, Stefania and Schulz, Kathrin L. and Hamburger, Matthias and Eckert, Anne. (2010) Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure. PLoS one, Vol. 5 , e12359.

Pagani, Lucia and Semenova, Ekaterina A. and Moriggi, Ermanno and Revell, Victoria L. and Hack, Lisa M. and Lockley, Steven W. and Arendt, Josephine and Skene, Debra J. and Meier, Fides and Izakovic, Jan and Wirz-Justice, Anna and Cajochen, Christian and Sergeeva, Oksana J. and Cheresiz, Sergei V. and Danilenko, Konstantin V. and Eckert, Anne and Brown, Steven A.. (2010) The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts. PLoS one, Vol. 5, H. 10 , e13376.

Götz, Jürgen and Lim, Yun-An and Ke, Yazi D. and Eckert, Anne and Ittner, Lars M.. (2010) Dissecting toxicity of tau and beta-amyloid. Neuro-degenerative Diseases, 7 (1-3). pp. 10-12.

Ittner, Lars M. and Ke, Yazi D. and Delerue, Fabien and Bi, Mian and Gladbach, Amadeus and van Eersel, Janet and Wölfing, Heidrun and Chieng, Billy C. and Christie, MacDonald J. and Napier, Ian A. and Eckert, Anne and Staufenbiel, Matthias and Hardeman, Edna and Götz, Jürgen. (2010) Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models. Cell, Vol. 142, H. 3. S. 387-397.

Lim, Yun-An and Rhein, Virginie and Baysang, Ginette and Meier, Fides and Poljak, Anne and Raftery, Mark J. and Guilhaus, Michael and Ittner, Lars M. and Eckert, Anne and Götz, Jürgen. (2010) Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics, Vol. 10, H. 8. S. 1621-1633.

Kurz, C. and Ungerer, I. and Lipka, U. and Kirr, S. and Schütt, T. and Eckert, A. and Leuner, K. and Müller, W. E.. (2010) The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by beta-amyloid peptide. British journal of pharmacology, Vol. 160, no. 2. S. 246-257.

Eckert, Anne and Schulz, Kathrin L. and Rhein, Virginie and Götz, Jürgen. (2010) Convergence of amyloid-beta and tau pathologies on mitochondria in vivo. Molecular neurobiology, Vol. 41, H. 2/3. S. 107-114.

Müller, Walter E. and Eckert, Anne and Kurz, Christopher and Eckert, Gunter Peter and Leuner, Kristina. (2010) Mitochondrial dysfunction : common final pathway in brain aging and Alzheimer's disease : therapeutic aspects. Molecular neurobiology, Vol. 41, H. 2/3. S. 159-171.

2009

Rhein, Virginie and Song, Xiaomin and Wiesner, Andreas and Ittner, Lars M. and Baysang, Ginette and Meier, Fides and Ozmen, Laurence and Bluethmann, Horst and Dröse, Stefan and Brandt, Ulrich and Savaskan, Egemen and Czech, Christian and Götz, Jürgen and Eckert, Anne. (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 47. S. 20057-20062.

Danielyan, L. and Schäfer, R. and Schulz, A. and Ladewig, T. and Lourhmati, A. and Buadze, M. and Schmitt, A. L. and Verleysdonk, S. and Kabisch, D. and Koeppen, K. and Siegel, G. and Proksch, B. and Kluba, T. and Eckert, A. and Köhle, C. and Schöneberg, T. and Northoff, H. and Schwab, M. and Gleiter, C. H.. (2009) Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin. Cell death and differentiation, Vol. 16, no. 12. S. 1599-1614.

Hauptmann, S. and Scherping, I. and Dröse, S. and Brandt, U. and Schulz, K. L. and Jendrach, M. and Leuner, K. and Eckert, A. and Müller, W. E.. (2009) Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice. Neurobiology of aging, Vol. 30, H. 10. S. 1574-1586.

Rhein, V. and Baysang, G. and Rao, S. and Meier, F. and Bonert, A. and Müller-Spahn, F. and Eckert, A.. (2009) Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells. Cellular and molecular neurobiology, Vol. 29, No. 6-7. S. 1063-1071.

Eckert, Anne. (2009) Spezielle Arzneimittelinteraktionen. Therapeutische Umschau, Bd. 66, H. 6. S. 485-492.

2008

Schaeffer, Véronique and Meyer, Laurence and Patte-Mensah, Christine and Eckert, Anne and Mensah-Nyagan, Ayikoe G.. (2008) Dose-dependent and sequence-sensitive effects of amyloid-beta peptide on neurosteroidogenesis in human neuroblastoma cells. Neurochemistry international, vol. 52, no. 6. S. 948-955.

Schaeffer, V. and Patte-Mensah, C. and Eckert, A. and Mensah-Nyagan, A. G.. (2008) Selective regulation of neurosteroid biosynthesis in human neuroblastoma cells under hydrogen peroxide-induced oxidative stress condition. Neuroscience, Vol. 151, H. 3. S. 758-770.

Eckert, Anne and Hauptmann, Susanne and Scherping, Isabel and Meinhardt, Jessica and Rhein, Virginie and Dröse, Stefan and Brandt, Ulrich and Fändrich, Marcus and Müller, Walter E. and Götz, Jürgen. (2008) Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice. Journal of molecular medicine, Vol. 86, no. 11. S. 1255-1267.

Eckert, A. and Böck, B. C. and Tagscherer, K. E. and Haas, T. L. and Grund, K. and Sykora, J. and Herold-Mende, C. and Ehemann, V. and Hollstein, M. and Chneiweiss, H. and Wiestler, O. D. and Walczak, H. and Roth, W.. (2008) The PEA-15/PED protein protects glioblastoma cells from glucose deprivation-induced apoptosis via the ERK/MAP kinase pathway. Oncogene, Vol. 27, H. 8. S. 1155-1166.

Eckert, Anne and Hauptmann, Susanne and Scherping, Isabel and Rhein, Virginie and Müller-Spahn, Franz and Götz, Jürgen and Müller, Walter E.. (2008) Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice. Neuro-degenerative Diseases, 5 (3-4). pp. 157-159.

Eckert, A. and Hauptmann, S. and Scherping, I. and Meinhardt, J. and Rhein, V. and Dröse, S. and Brandt, U. and Fändrich, M. and Müller, W. E. and Götz, J.. (2008) Oligomeric and fibrillar species of beta-amyloid (Abeta42) both impair mitochondrial function in P301L tau transgenic mice. Journal of molecular medicine, Vol. 86, no. 11. S. 1255-1267.

Schaeffer, V. and Patte-Mensah, C. and Eckert, A. and Mensah-Nyagan, A. G.. (2008) Selective regulation of neurosteroid biosynthesis in human neuroblastoma cells under hydrogen peroxide-induced oxidative stress condition. Neuroscience, Vol. 151. S. 758-770.

2007

Schindowski, Katharina and Eckert, Anne and Peters, Jürgen and Gorriz, Corinna and Schramm, Uta and Weinandi, Thomas and Maurer, Konrad and Frölich, Lutz and Müller, Walter E.. (2007) Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model : implications for immunotherapy. Neuromolecular medicine, Vol. 9, No. 4. S. 340-354.

Leschik, Julia and Welzel, Alfred and Weissmann, Carina and Eckert, Anne and Brandt, Roland. (2007) Inverse and distinct modulation of tau-dependent neurodegeneration by presenilin 1 and amyloid-beta in cultured cortical neurons : evidence that tau phosphorylation is the limiting factor in amyloid-beta-induced cell death. Journal of neurochemistry, Vol. 101, H. 5. S. 1303-1315.

Abdel-Kader, Reham and Hauptmann, Susanne and Keil, Uta and Scherping, Isabel and Leuner, Kristina and Eckert, Anne and Müller, Walter E.. (2007) Stabilization of mitochondrial function by Ginkgo biloba extract (EGb 761). Pharmacological research, Vol. 56, No. 6. S. 493-502.

Rhein, Virginie and Eckert, Anne. (2007) Effects of Alzheimer's amyloid-beta and tau protein on mitochondrial function : role of glucose metabolism and insulin signalling. Archives of physiology and biochemistry, Vol. 113, No. 3. S. 131-141.

Caggiano, Thomas J. and Brazzale, Antony and Ho, Douglas M. and Kraml, Christina M. and Trybulski, Eugene and Chadwick, Christopher C. and Chippari, Sue and Borges-Marcucci, Lisa and Eckert, Amy and Keith, James C. and Kenney, Thomas and Harnish, Douglas C.. (2007) Estrogen receptor dependent inhibitors of NF-κB transcriptional activation-1 synthesis and biological evaluation of substituted 2-cyanopropanoic acid derivatives : pathway selective inhibitors of NF-κB, a potential treatment for rheumatoid arthritis. Journal of medicinal chemistry, Vol. 50, no. 22. S. 5245-5248.

Chalimoniuk, Ma?gorzata and Stolecka, Anna and Caka?a, Magdalena and Hauptmann, Susane and Schulz, Kris and Lipka, Uta and Leuner, Kristine and Eckert, Anne and Muller, Walter E. and Strosznajder, Joanna B.. (2007) Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells. Acta biochimica Polonica, Vol. 54, Nr. 3. S. 611-623.

Leuner, Kristina and Hauptmann, Susanne and Abdel-Kader, Reham and Scherping, Isabel and Keil, Uta and Strosznajder, Johanna B. and Eckert, Anne and Müller, Walter E.. (2007) Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease? Antioxidants & redox signaling, Vol. 9, No. 10. S. 1659-1675.

Savaskan, Egemen and Jockers, Ralf and Ayoub, Mohammed and Angeloni, Debora and Fraschini, Franco and Flammer, Josef and Eckert, Anne and Müller-Spahn, Franz and Meyer, Peter. (2007) The MT2 melatonin receptor subtype is present in human retina and decreases in Alzheimer's disease. Current Alzheimer research, Vol. 4, No. 1. S. 47-51.

Copanaki, Ekaterini and Schürmann, Tina and Eckert, Anne and Leuner, Kristina and Müller, Walter E. and Prehn, Jochen H. M. and Kögel, Donat. (2007) The amyloid precursor protein potentiates CHOP induction and cell death in response to ER Ca2+ depletion. Biochimica et biophysica acta. Molecular cell research, Vol. 1773, Issue 2. S. 157-165.

Leuner, K. and Pantel, J. and Frey, C. and Schindowski, K. and Schulz, K. and Wegat, T. and Maurer, K. and Eckert, A. and Müller, W. E.. (2007) Enhanced apoptosis, oxidative stress and mitochondrial dysfunction in lymphocytes as potential biomarkers for Alzheimer's disease. Journal of neural transmission. Supplementum, Vol. 72. S. 207-215.

2006

Schultze, Kerstin and Böck, Barbara and Eckert, Anika and Oevermann, Lena and Ramacher, Dirk and Wiestler, Otmar and Roth, Wilfried. (2006) Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin. Apoptosis, 11 (9). pp. 1503-1512.

Schindowski, K. and Peters, J. and Gorriz, C. and Schramm, U. and Weinandi, T. and Leutner, S. and Maurer, K. and Frölich, L. and Müller, W. E. and Eckert, A.. (2006) Apoptosis of CD4+ T and natural killer cells in Alzheimer's disease. Pharmacopsychiatry, Vol. 39, H. 6. S. 220-228.

Frey, C. and Bonert, A. and Kratzsch, T. and Rexroth, G. and Rösch, W. and Müller-Spahn, F. and Maurer, K. and Müller, W. E. and Eckert, A.. (2006) Apolipoprotein E epsilon 4 is associated with an increased vulnerability to cell death in Alzheimer's disease. Journal of neural transmission, Vol. 113, No. 11. S. 1753-1761.

Schuessel, Katrin and Frey, Claudia and Jourdan, Claudia and Keil, Uta and Weber, Claudia C. and Müller-Spahn, Franz and Müller, Walter E. and Eckert, Anne. (2006) Aging sensitizes toward ROS formation and lipid peroxidation in PS1M146L transgenic mice. Free radical biology & medicine, Vol. 40, H. 5. S. 850-562.

Keil, Uta and Scherping, Isabel and Hauptmann, Susanne and Schuessel, Katin and Eckert, Anne and Müller, Walter E.. (2006) Piracetam improves mitochondrial dysfunction following oxidative stress. British journal of pharmacology, Vol. 147, no. 2. S. 199-208.

Schaeffer, Véronique and Patte-Mensah, Christine and Eckert, Anne and Mensah-Nyagan, Ayikoe G.. (2006) Modulation of neurosteroid production in human neuroblastoma cells by Alzheimer's disease key proteins. Journal of neurobiology, Vol. 66, H. 8. S. 868-881.

Brunner, P. and Sözer-Topcular, N. and Jockers, R. and Ravid, R. and Angeloni, D. and Fraschini, F. and Eckert, A. and Müller-Spahn, F. and Savaskan, E.. (2006) Pineal and cortical melatonin receptors MT1 and MT2 are decreased in Alzheimer's disease. European journal of histochemistry, Vol. 50, No. 4. S. 311-316.

Hauptmann, Susanne and Keil, Uta and Scherping, Isabel and Bonert, Astrid and Eckert, Anne and Müller, Walter E.. (2006) Mitochondrial dysfunction in sporadic and genetic Alzheimer's disease. Experimental gerontology, Vol. 41, no. 7. S. 668-673.

Chalimoniuk, Ma?gorzata and G?owacka, J. and Zabielna, A. and Eckert, A. and Strosznajder, J. B.. (2006) Nitric oxide alters arachidonic acid turnover in brain cortex synaptoneurosomes. Neurochemistry international, vol. 48, no. 1. S. 1-8.

Keil, Uta and Hauptmann, Susanne and Bonert, Astrid and Scherping, Isabel and Eckert, Anne and Müller, Walter E.. (2006) Mitochondrial dysfunction induced by disease relevant AbetaPP and tau protein mutations. Journal of Alzheimer's disease, Vol. 9, no. 2. S. 139-146.

2005

David, Della C. and Hauptmann, Susanne and Scherping, Isabel and Schuessel, Katrin and Keil, Uta and Rizzu, Patrizia and Ravid, Rivka and Dröse, Stefan and Brandt, Ulrich and Müller, Walter E. and Eckert, Anne and Götz, Jürgen. (2005) Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. Journal of biological chemistry, Vol. 280, H. 25. S. 23802-23814.

Eckert, Anne. (2005) Stellenwert von Nimodipin in der Demenztherapie : Calcium-Hypothese der Demenz. Pharmazie in unserer Zeit, Vol. 34, issue 5. p. 392-398.

Leutner, S. and Schindowski, K. and Frölich, L. and Maurer, K. and Kratzsch, T. and Eckert, A. and Müller, W. E.. (2005) Enhanced ROS-generation in lymphocytes from Alzheimer's patients. Pharmacopsychiatry, Vol. 38, H. 6. S. 312-315.

Schuessel, Katrin and Schäfer, Stephanie and Bayer, Thomas A. and Czech, Christian and Pradier, Laurent and Müller-Spahn, Franz and Müller, Walter E. and Eckert, Anne. (2005) Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice. Neurobiology of disease, Vol. 18, no. 1. S. 89-99.

Savaskan, Egemen and Ayoub, Mohammed A. and Ravid, Rivka and Angeloni, Debora and Fraschini, Franco and Meier, Fides and Eckert, Anne and Müller-Spahn, Franz and Jockers, Ralf. (2005) Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease. Journal of pineal research, Vol. 38, no. 1. S. 10-16.

Eckert, Anne and Keil, Uta and Scherping, Isabel and Hauptmann, Susanne and Müller, Walter E.. (2005) Stabilization of mitochondrial membrane potential and improvement of neuronal energy metabolism by Ginkgo biloba extract EGb 761. Annals of the New York Academy of Sciences, Vol. 1056. S. 474-485.

2004

Strosznajder, Joanna B. and Je?ko, Henryk and Zambrzycka, Agata and Eckert, Anne and Chalimoniuk, Ma?gorzata. (2004) Age-related alteration of activity and gene expression of endothelial nitric oxide synthase in different parts of the brain in rats. Neuroscience letters, Vol. 370, H. 2-3. S. 175-179.

Schuessel, K. and Leutner, S. and Cairns, N. J. and Müller, W. E. and Eckert, A.. (2004) Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain. Journal of neural transmission, Vol. 111, No. 9. S. 1167-1182.

Keil, U. and Bonert, A. and Marques, C. A. and Strosznajder, J. B. and Müller-Spahn, F. and Müller, W. E. and Eckert, A.. (2004) Elevated nitric oxide production mediates beta-amyloid-induced mitochondria failure. Polish journal of pharmacology, Vol. 56, no. 5. S. 631-634.

Keil, Uta and Bonert, Astrid and Marques, Celio A. and Scherping, Isabel and Weyermann, Jörg and Strosznajder, Joanna B. and Müller-Spahn, Franz and Haass, Christian and Czech, Christian and Pradier, Laurent and Müller, Walter E. and Eckert, Anne. (2004) Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis. Journal of biological chemistry, Vol. 279, H. 48. S. 50310-50320.

2003

Bayer, Thomas A. and Schäfer, Stephanie and Simons, Andreas and Kemmling, André and Kamer, Thomas and Tepest, Ralf and Eckert, Anne and Schüssel, Katrin and Eikenberg, Oliver and Sturchler-Pierrat, Christine and Abramowski, Dorothee and Staufenbiel, Matthias and Multhaup, Gerd. (2003) Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 24. S. 14187-14192.

Marques, Celio A. and Keil, Uta and Bonert, Astrid and Steiner, Barbara and Haass, Christian and Muller, Walter E. and Eckert, Anne. (2003) Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation : oxidative stress, caspases, and the JNK pathway. Journal of biological chemistry, Vol. 278, H. 30. S. 28294-28302.

Eckert, A. and Keil, U. and Kressmann, S. and Schindowski, K. and Leutner, S. and Leutz, S. and Müller, W. E.. (2003) Effects of EGb 761 Ginkgo biloba extract on mitochondrial function and oxidative stress. Pharmacopsychiatry, Vol. 36, Suppl. 1. S. 15-23.

Schindowski, Katharina and Kratzsch, Tilmann and Peters, Jürgen and Steiner, Barbara and Leutner, Silke and Touchet, Natalie and Maurer, Konrad and Czech, Christian and Pradier, Laurent and Frölich, Lutz and Müller, Walter E. and Eckert, Anne. (2003) Impact of aging : sporadic, and genetic risk factors on vulnerability to apoptosis in Alzheimer's disease. Neuromolecular medicine, Vol. 4, No. 3. S. 161-178.

Kögel, Donat and Schomburg, Robert and Schürmann, Tina and Reimertz, Claus and König, Hans-Georg and Poppe, Monika and Eckert, Anne and Müller, Walter E. and Prehn, Jochen H. M.. (2003) The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis. Journal of neurochemistry, Vol. 87, H. 1. S. 248-256.

Eckert, Anne and Keil, Uta and Marques, Celio A. and Bonert, Astrid and Frey, Claudia and Schüssel, Katrin and Müller, Walter E.. (2003) Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease. Biochemical Pharmacology, Volume 76, Issue 10. S. 1184-1193.

Eckert, Anne and Marques, Celio A. and Keil, Uta and Schüssel, Katrin and Müller, Walter E.. (2003) Increased apoptotic cell death in sporadic and genetic Alzheimer's disease. Annals of the New York Academy of Sciences, vol. 1010. S. 604-609.

2002

Eckert, Anne. (2002) Alois Alzheimer und die Alzheimer Krankheit : aus der Frankfurter Anstalt für Irre und Epileptische. Pharmazie in unserer Zeit, Vol. 31, issue 4. p. 356-360.

Leutz, Steffen and Steiner, Barbara and Marques, Celio A. and Haass, Christian and Müller, Walter E. and Eckert, Anne. (2002) Reduction of trophic support enhances apoptosis in PC12 cells expressing Alzheimer's APP mutation and sensitizes cells to staurosporine-induced cell death. Journal of molecular neuroscience, Vol. 18, No. 3. S. 189-201.

Schindowski, Katharina and Fröhlich, Lutz and Maurer, Konrad and Müller, Walter E. and Eckert, Anne. (2002) Age-related impairment of human T lymphocytes' activation : specific differences between CD4(+) and CD8(+) subsets. Mechanisms of ageing and development, Vol. 123, no. 4. S. 375-390.

2001

Eckert, A. and Oster, M. and Zerfass, R. and Hennerici, M. and Müller, W. E.. (2001) Elevated levels of fragmented DNA nucleosomes in native and activated lymphocytes indicate an enhanced sensitivity to apoptosis in sporadic Alzheimer's disease. Specific differences to vascular dementia. Dementia and Geriatric Cognitive Disorders, 12 (2). pp. 98-105.

Eckert, A. and Schindowski, K. and Leutner, S. and Luckhaus, C. and Touchet, N. and Czech, C. and Müller, W. E.. (2001) Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice. Neurobiology of disease, Vol. 8, no. 2. S. 331-342.

Schindowski, K. and Leutner, S. and Kressmann, S. and Eckert, A. and Müller, W. E.. (2001) Age-related increase of oxidative stress-induced apoptosis in mice prevention by Ginkgo biloba extract (EGb761). Journal of neural transmission, Vol. 108, No. 8-9. S. 969-978.

Eckert, A. and Steiner, B. and Marques, C. and Leutz, S. and Romig, H. and Haass, C. and Müller, W. E.. (2001) Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation. Journal of neuroscience research, Vol. 64, No. 2. S. 183-192.

Leutner, S. and Eckert, A. and Müller, W. E.. (2001) ROS generation, lipid peroxidation and antioxidant enzyme activities in the aging brain. Journal of neural transmission, Vol. 108, No. 8-9. S. 955-967.

2000

Leutner, S. and Czech, C. and Schindowski, K. and Touchet, N. and Eckert, A. and Müller, W. E.. (2000) Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations. Neuroscience letters, Vol. 292, H. 2. S. 87-90.

Schindowski, K. and Leutner, S. and Müller, W. E. and Eckert, A.. (2000) Age-related changes of apoptotic cell death in human lymphocytes. Neurobiology of aging, Vol. 21, H. 5. S. 661-670.

Velbinger, K. and De Vry, J. and Jentzsch, K. and Eckert, A. and Henn, F. and Müller, W. E.. (2000) Acute stress induced modifications of calcium signaling in learned helpless rats. Pharmacopsychiatry, Vol. 33, H. 4. S. 132-137.

1999

Eckert, A. and Segond von Banchet, G. and Sopper, S. and Petersen, M.. (1999) Spatio-temporal pattern of induction of bradykinin receptors and inflammation in rat dorsal root ganglia after unilateral nerve ligation. Pain, Vol. 83, H. 3. S. 487-497.

Müller, W. E. and Eckert, G. P. and Eckert, A.. (1999) Piracetam: novelty in a unique mode of action. Pharmacopsychiatry, Vol. 32, Suppl. 1. S. 2-9.

1998

Petersen, M. and Klusch, A. and Eckert, A.. (1998) The proportion of isolated rat dorsal root ganglion neurones responding to bradykinin increases with time in culture. Neuroscience letters, Vol. 252, H. 2. S. 143-146.

Eckert, A. and Cotman, C. W. and Zerfass, R. and Hennerici, M. and Müller, W. E.. (1998) Enhanced vulnerability to apoptotic cell death in sporadic Alzheimer's disease. NeuroReport, Vol. 9, H. 11. S. 2443-2446.

Eckert, A. and Reiff, J. and Müller, W. E.. (1998) Arzneimittelinteraktionen mit Antidepressiva : Vorteile des spezifischen Serotonin-Wiederaufnahmehemmers Citalopram. Medizinische Monatsschrift für Pharmazeuten, Vol. 21, H. 5. S. 138-150.

Eckert, A. and Cotman, C. W. and Zerfass, R. and Hennerici, M. and Müller, W. E.. (1998) Lymphocytes as cell model to study apoptosis in Alzheimer's disease: vulnerability to programmed cell death appears to be altered. Journal of neural transmission. Supplementum, Vol. 54. S. 259-267.

Eckert, A. and Förstl, H. and Zerfass, R. and Oster, M. and Hennerici, M. and Müller, W. E.. (1998) Changes of intracellular calcium regulation in Alzheimer's disease and vascular dementia. Journal of neural transmission. Supplementum, Vol. 54. S. 201-210.

1997

Eckert, A. and Förstl, H. and Zerfass, R. and Hennerici, M. and Müller, W. E.. (1997) Free intracellular calcium in peripheral cells in Alzheimer's disease. Neurobiology of aging, Vol. 18, H. 3. S. 281-284.

Eckert, A. and Oster, M. and Förstl, H. and Hennerici, M. and Müller, W. E.. (1997) Impaired calcium regulation in subcortical vascular encephalopathy. Stroke, Vol. 28, no. 7 , pp. 1351-1356.

1996

Hartmann, H. and Velbinger, K. and Eckert, A. and Müller, W. E.. (1996) Region-specific downregulation of free intracellular calcium in the aged rat brain. Neurobiology of aging, Vol. 17, H. 4. S. 557-563.

Eckert, A. and Förstl, H. and Zerfass, R. and Hartmann, H. and Müller, W. E.. (1996) Lymphocytes and neutrophils as peripheral models to study the effect of beta-amyloid on cellular calcium signalling in Alzheimer's disease. Life sciences, Vol. 59, no. 5-6. S. 499-510.

Hartmann, H. and Eckert, A. and Velbinger, K. and Rewsin, M. and Müller, W. E.. (1996) Down-regulation of free intracellular calcium in dissociated brain cells of aged mice and rats. Life sciences, Vol. 59, no. 5-6. S. 435-449.

Müller, W. E. and Eckert, A. and Hartmann, H. and Velbinger, K. and Förstl, H.. (1996) Zur Kalziumhypothese der Hirnalterung. Der Nervenarzt, Jg. 67, H. 1. S. 15-24.

Müller, W. E. and Hartmann, H. and Eckert, A. and Velbinger, K. and Förstl, H.. (1996) Free intracellular calcium in aging and Alzheimer's disease. Annals of the New York Academy of Sciences, Vol. 786. S. 305-320.

1995

Eckert, A. and Förstl, H. and Hartmann, H. and Czech, C. and Mönning, U. and Beyreuther, K. and Müller, W. E.. (1995) The amplifying effect of beta-amyloid on cellular calcium signalling is reduced in Alzheimer's disease. NeuroReport, Vol. 6, H. 8. S. 1199-1202.

Müller, W. E. and Koch, S. and Eckert, A. and Hartmann, H. and Scheuer, K.. (1995) β-amyloid peptide decreases membrane fluidity. Brain research, Vol. 674, no. 1. S. 133-136.

1994

Eckert, A. and Gann, H. and Riemann, D. and Aldenhoff, J. and Müller, W. E.. (1994) Platelet and lymphocyte free intracellular calcium in affective disorders. European archives of psychiatry and clinical neuroscience, Vol. 243, H. 5. S. 235-239.

Hartmann, H. and Eckert, A. and Förstl, H. and Müller, W. E.. (1994) Similar age-related changes of free intracellular calcium in lymphocytes and central neurons : effects of Alzheimer's disease. European archives of psychiatry and clinical neuroscience, Vol. 243, H. 5. S. 218-223.

Eckert, A. and Hartmann, H. and Förstl, H. and Müller, W. E.. (1994) Alterations of intracellular calcium regulation during aging and Alzheimer's disease in nonneuronal cells. Life sciences, Vol. 55, no. 25-26. S. 2019-2029.

Hartmann, H. and Eckert, A. and Müller, W. E.. (1994) Apolipoprotein E and cholesterol affect neuronal calcium signalling: the possible relationship to beta-amyloid neurotoxicity. Biochemical and Biophysical Research Communications, Vol. 200, H. 3. S. 1185-1192.

Hartmann, H. and Eckert, A. and Müller, W. E.. (1994) Disturbances of the neuronal calcium homeostasis in the aging nervous system. Life sciences, Vol. 55, no. 25-26. S. 2011-2018.

1993

Eckert, A. and Gann, H. and Riemann, D. and Aldenhoff, J. and Müller, W. E.. (1993) Elevated intracellular calcium levels after 5-HT2 receptor stimulation in platelets of depressed patients. Biological Psychiatry, Vol. 34, H. 8. S. 565-568.

Eckert, A. and Förstl, H. and Hartmann, H. and Müller, W. E.. (1993) Decreased beta-amyloid sensitivity in Alzheimer's disease. Lancet, Vol. 342, no. 8874. S. 805-806.

Eckert, A. and Hartmann, H. and Müller, W. E.. (1993) β-Amyloid protein enhances the mitogen-induced calcium response in circulating human lymphocytes. FEBS letters, Vol. 330, H. 1. S. 49-52.

Hartmann, H. and Eckert, A. and Müller, W. E.. (1993) β-Amyloid protein amplifies calcium signalling in central neurons from the adult mouse. Biochemical and Biophysical Research Communications, Vol. 194, H. 3. S. 1216-1220.

Hartmann, H. and Eckert, A. and Müller, W. E.. (1993) Aging enhances the calcium sensitivity of central neurons of the mouse as an adaptive response to reduced free intracellular calcium. Neuroscience letters, Vol. 152, H. 1-2. S. 181-184.