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Dissecting toxicity of tau and beta-amyloid

Götz, Jürgen and Lim, Yun-An and Ke, Yazi D. and Eckert, Anne and Ittner, Lars M.. (2010) Dissecting toxicity of tau and beta-amyloid. Neuro-degenerative Diseases, 7 (1-3). pp. 10-12.

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Official URL: http://edoc.unibas.ch/dok/A6003957

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Abstract

How beta-amyloid (Abeta) and tau exert toxicity in Alzheimer's disease is only partly understood. Major questions include (1) which aggregation state of Abeta confers toxicity, (2) do amyloidogenic proteins have similar mechanisms of toxicity, and (3) does soluble tau interfere with cellular functions?
Faculties and Departments:03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Erwachsenenpsychiatrie (Lang)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Erwachsenenpsychiatrie (Lang)
UniBasel Contributors:Eckert, Anne
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Karger
ISSN:1660-2854
e-ISSN:1660-2862
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
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Last Modified:25 Oct 2017 08:59
Deposited On:07 Dec 2012 13:02

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