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2019

Trinh, Beckey and Hepprich, Matthias and Betz, Matthias J. and Burkard, Thilo and Cavelti-Weder, Claudia and Seelig, Eleonora and Meienberg, Fabian and Kratschmar, Denise V. and Beuschlein, Felix and Reincke, Martin and Odermatt, Alex and Hall, Michael N. and Donath, Marc Y. and Swierczynska, Marta M.. (2019) Treatment of Primary Aldosteronism with mTORC1 Inhibitors. The Journal of Clinical Endocrinology and Metabolism, 104 (10). pp. 4703-4714.

2016

Cavelti-Weder, C. and Timper, K. and Seelig, E. and Keller, C. and Osranek, M. and Lassing, U. and Spohn, G. and Maurer, P. and Muller, P. and Jennings, G. T. and Willers, J. and Saudan, P. and Donath, M. Y. and Bachmann, M. F.. (2016) Development of an Interleukin-1β Vaccine in Patients with Type 2 Diabetes. Molecular Therapy, 24 (5). pp. 1003-1012.

Timper, K. and Dalmas, E. and Dror, E. and Rutti, S. and Thienel, C. and Sauter, N. S. and Bouzakri, K. and Bedat, B. and Pattou, F. and Kerr-Conte, J. and Boni-Schnetzler, M. and Donath, M. Y.. (2016) Glucose-Dependent Insulinotropic Peptide Stimulates Glucagon-Like Peptide 1 Production by Pancreatic Islets via Interleukin 6, Produced by α Cells. Gastroenterology, 151 (1). pp. 165-179.

Seelig, Eleonora and Timper, Katharina and Falconnier, Claudine and Stoeckli, Rolf and Bilz, Stefan and Oram, Richard A. and McDonald, Timothy James and Donath, Marc Y.. (2016) Interleukin-1 antagonism in type 1 diabetes of long duration. Diabetes & metabolism, 42 (6). pp. 453-456.

Pollack, Rena M. and Donath, Marc Y. and LeRoith, Derek and Leibowitz, Gil. (2016) Anti-inflammatory Agents in the Treatment of Diabetes and Its Vascular Complications. Diabetes Care, 39 Suppl 2. pp. 244-252.

Falconnier Bendik, Claudine and Donath, Marc Y.. (2016) Individualisierte Behandlungsstrategien bei Diabetes mellitus Typ 2. Therapeutische Umschau, 73 (6). pp. 340-348.

Donath, Marc Y.. (2016) Multiple benefits of targeting inflammation in the treatment of type 2 diabetes. Diabetologia, 59 (4). pp. 679-682.

Donath, Marc Y.. (2016) Behandlung von Typ-2-Diabetes: Praxisnahe Empfehlungen [Management of Type 2 Diabetes: a Practical Approach]. Praxis, 105 (12). pp. 699-702.

2015

Timper, K. and Seelig, E. and Tsakiris, D. A. and Donath, M. Y.. (2015) Safety, pharmacokinetics, and preliminary efficacy of a specific anti-IL-1alpha therapeutic antibody (MABp1) in patients with type 2 diabetes mellitus. Journal of Diabetes and its Complications, 29 (7). pp. 955-960.

Sauter, N. S. and Thienel, C. and Plutino, Y. and Kampe, K. and Dror, E. and Traub, S. and Timper, K. and Bedat, B. and Pattou, F. and Kerr-Conte, J. and Jehle, A. W. and Boni-Schnetzler, M. and Donath, M. Y.. (2015) Angiotensin II Induces Interleukin-1β–Mediated Islet Inflammation and β-Cell Dysfunction Independently of Vasoconstrictive Effects. Diabetes, 64 (4). pp. 1273-1283.

Nordmann, Thierry M. and Seelig, Eleonara and Timper, Katharina and Cordes, Mareike and Coslovsky, Michael and Hanssen, Henner and Schmidt-Trucksäss, Arno and Donath, Marc Y.. (2015) Muscle-Derived IL-6 Is Not Regulated by IL-1 during Exercise. A Double Blind, Placebo-Controlled, Randomized Crossover Study. PLoS ONE, 10 (10). e0139662.

Herder, C. and Donath, M. Y.. (2015) Interleukin-1 receptor antagonist: friend or foe to the heart? The Lancet Diabetes & Endocrinology, 3 (4). pp. 228-229.

Herder, C. and Dalmas, E. and Boni-Schnetzler, M. and Donath, M. Y.. (2015) The IL-1 Pathway in Type 2 Diabetes and Cardiovascular Complications. Trends in Endocrinology and Metabolism, 26 (10). pp. 551-563.

Caduff, Andreas and Zanon, Mattia and Mueller, Martin and Zakharov, Pavel and Feldman, Yuri and De Feo, Oscar and Donath, Marc and Stahel, Werner A. and Talary, Mark S.. (2015) The Effect of a Global, Subject, and Device-Specific Model on a Noninvasive Glucose Monitoring Multisensor System. Journal of Diabetes Science and Technology, 9 (4). pp. 865-872.

2014

Wueest, Stephan and Item, Flurin and Boyle, Christina N. and Jirkof, Paulin and Cesarovic, NNikola and Ellingsgaard, Helga and Böni-Schnetzler, Marianne and Timper, Katharina and Arras, Margarete and Donath, Marc Y. and Lutz, Thomas A. and Schoenle, Eugen J. and Konrad, Daniel. (2014) Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 306 (11). R861-R867.

Rutti, Sabine and Arous, Caroline and Schvartz, Domitille and Timper, Katharina and Sanchez, Jean-Charles and Dermitzakis, Emmanouil and Donath, Marc Y. and Halban, Philippe A. and Bouzakri, Karim. (2014) Fractalkine (CX3CL1), a new factor protecting beta-cells against TNFalpha. Molecular Metabolism, 3 (7). pp. 731-741.

Donath, Marc Y. and Hess, Christoph and Palmer, Ed. (2014) What is the role of autoimmunity in type 1 diabetes? A clinical perspective. Diabetologia, 57 (4). pp. 653-655.

Donath, Marc Y.. (2014) Targeting inflammation in the treatment of type 2 diabetes: time to start. Nature Reviews. Drug Discovery, 13 (6). pp. 465-476.

Dalmas, Elise and Donath, Marc Y.. (2014) A role for interleukin-22 in the alleviation of metabolic syndrome. Nat Med, 20 (12). pp. 1379-1381.

2013

Timper, K. and Hruz, P. and Beglinger, C. and Donath, M. Y.. (2013) Infliximab in the treatment of Crohn disease and type 1 diabetes. Diabetes care, Vol. 36, H. 7 , e90-e91.

Donath, M. Y. and Dalmas, E. and Sauter, N. S. and Boni-Schnetzler, M.. (2013) Inflammation in obesity and diabetes: islet dysfunction and therapeutic opportunity. Cell metabolism, Vol. 17, H. 6. pp. 860-872.

Donath, M. Y. and Burcelin, R.. (2013) GLP-1 effects on islets: hormonal, neuronal, or paracrine? Diabetes care, Vol. 36, suppl. 2 , S145-S148.

Moran, A. and Bundy, B. and Becker, D. J. and DiMeglio, L. A. and Gitelman, S. E. and Goland, R. and Greenbaum, C. J. and Herold, K. C. and Marks, J. B. and Raskin, P. and Sanda, S. and Schatz, D. and Wherrett, D. K. and Wilson, D. M. and Krischer, J. P. and Skyler, J. S. and Pickersgill, L. and de Koning, E. and Ziegler, A. G. and Boehm, B. and Badenhoop, K. and Schloot, N. and Bak, J. F. and Pozzilli, P. and Mauricio, D. and Donath, M. Y. and Castano, L. and Wagner, A. and Lervang, H. H. and Perrild, H. and Mandrup-Poulsen, T. and Aida Study Group, and Pociot, F. and Dinarello, C. A.. (2013) Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials. Lancet, Vol. 381, no. 9881. pp. 1905-1915.

Tang, C. and Naassan, A. E. and Chamson-Reig, A. and Koulajian, K. and Goh, T. T. and Yoon, F. and Oprescu, A. I. and Ghanim, H. and Lewis, G. F. and Dandona, P. and Donath, M. Y. and Ehses, J. A. and Arany, E. and Giacca, A.. (2013) Susceptibility to fatty acid-induced beta-cell dysfunction is enhanced in prediabetic diabetes-prone biobreeding rats: a potential link between beta-cell lipotoxicity and islet inflammation. Endocrinology, Vol. 154, H. 1. pp. 89-101.

Donath, M. Y.. (2013) When metabolism met immunology. Nature immunology, Vol. 14, H. 5. pp. 421-422.

Donath, M. Y.. (2013) Targeting inflammation in the treatment of type 2 diabetes. Diabetes, obesity and metabolism, Vol. 15, suppl. 3. pp. 193-196.

Boni-Schnetzler, M. and Donath, M. Y.. (2013) How biologics targeting the IL-1 system are being considered for the treatment of type 2 diabetes. British journal of clinical pharmacology, Vol. 76, H. 2. pp. 263-268.

Biason-Lauber, A. and Boni-Schnetzler, M. and Hubbard, B. P. and Bouzakri, K. and Brunner, A. and Cavelti-Weder, C. and Keller, C. and Meyer-Boni, M. and Meier, D. T. and Brorsson, C. and Timper, K. and Leibowitz, G. and Patrignani, A. and Bruggmann, R. and Boily, G. and Zulewski, H. and Geier, A. and Cermak, J. M. and Elliott, P. and Ellis, J. L. and Westphal, C. and Knobel, U. and Eloranta, J. J. and Kerr-Conte, J. and Pattou, F. and Konrad, D. and Matter, C. M. and Fontana, A. and Rogler, G. and Schlapbach, R. and Regairaz, C. and Carballido, J. M. and Glaser, B. and McBurney, M. W. and Pociot, F. and Sinclair, D. A. and Donath, M. Y.. (2013) Identification of a SIRT1 mutation in a family with type 1 diabetes. Cell metabolism, Vol. 17, H. 3. pp. 448-455.

2012

Erener, S. and Mirsaidi, A. and Hesse, M. and Tiaden, A. N. and Ellingsgaard, H. and Kostadinova, R. and Donath, M. Y. and Richards, P. J. and Hottiger, M. O.. (2012) ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high-fat diet and impairs adipocyte function and differentiation. The FASEB Journal, Vol. 26, H. 6. pp. 2631-2638.

Cavelti-Weder, C. and Muggli, B. and Keller, C. and Babians-Brunner, A. and Biason-Lauber, A. and Donath, M. Y. and Schmid-Grendelmeier, P.. (2012) Successful use of omalizumab in an inadequately controlled type 2 diabetic patient with severe insulin allergy. Diabetes care, Vol. 35, H. 6 , e41.

Rutti, S. and Sauter, N. S. and Bouzakri, K. and Prazak, R. and Halban, P. A. and Donath, M. Y.. (2012) In vitro proliferation of adult human beta-cells. PLoS ONE, Vol. 7, H. 4 , e35801.

Timper, K. and Donath, M. Y.. (2012) Diabetes mellitus Type 2 - the new face of an old lady. Swiss medical weekly, Vol. 142 , w13635.

Levendal, R. A. and Schumann, D. and Donath, M. and Frost, C. L.. (2012) Cannabis exposure associated with weight reduction and beta-cell protection in an obese rat model. Phytomedicine, Vol. 19, H. 7. pp. 575-582.

Cavelti-Weder, C. and Babians-Brunner, A. and Keller, C. and Stahel, M. A. and Kurz-Levin, M. and Zayed, H. and Solinger, A. M. and Mandrup-Poulsen, T. and Dinarello, C. A. and Donath, M. Y.. (2012) Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes. Diabetes care, Vol. 35, H. 8. pp. 1654-1662.

2011

Donath, M. Y. and Shoelson, S. E.. (2011) Type 2 diabetes as an inflammatory disease. Nature reviews. Immunology, Vol. 11, H. 2. pp. 98-107.

Cavelti-Weder, Claudia and Furrer, Romana and Keller, Cornelia and Babians-Brunner, Andrea and Solinger, Alan M. and Gast, H. and Fontana, A. and Donath, Marc Y. and Penner, Iris K.. (2011) Inhibition of IL-1beta improves fatigue in type 2 diabetes. Diabetes care : the journal of clinical and applied research and education : a journal of the American Diabetes Association, Vol. 34. H. 10 , e158.

Mossdorf, E. and Marzolini, C. and Fasel, D. and Mello Fayet, A. and Blum, C. and Donath, M. and Battegay, M.. (2011) [Drug-drug interactions with HIV treatments]. Schweizerische Rundschau für Medizin PRAXIS, Vol. 100. pp. 1193-1196.

Donath, and Marc, Y.. (2011) Inflammation as a sensor of metabolic stress in obesity and type 2 diabetes. Endocrinology, Vol. 152, H. 11. pp. 4005-4006.

Böni-Schnetzler, Marianne and Donath, Marc Y.. (2011) Increased IL-1β activation, the culprit not only for defective insulin secretion but also for insulin resistance? Cell research, Vol. 21, H. 7. pp. 995-997.

Bouzakri, K. and Plomgaard, P. and Berney, T. and Donath, M. Y. and Pedersen, B. K. and Halban, P. A.. (2011) Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscle. Diabetes, Vol. 60, H. 4. pp. 1111-1121.

Ellingsgaard, H. and Hauselmann, I. and Schuler, B. and Habib, A. M. and Baggio, L. L. and Meier, D. T. and Eppler, E. and Bouzakri, K. and Wueest, S. and Muller, Y. D. and Hansen, A. M. and Reinecke, M. and Konrad, D. and Gassmann, M. and Reimann, F. and Halban, P. A. and Gromada, J. and Drucker, D. J. and Gribble, F. M. and Ehses, J. A. and Donath, M. Y.. (2011) Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and α-cells. Nature medicine, Vol. 17, H. 11. pp. 1481-1489.

Traber, Ghislaine and Baumgartner, Matthias R. and Schwarz, Urs and Pangalu, Athina and Donath, Marc Y. and Landau, Klara. (2011) Subacute bilateral visual loss in methylmalonic acidemia. Journal of neuro-ophthalmology, Vol. 31, H. 4. pp. 344-346.

Caduff, A. and Mueller, M. and Megej, A. and Dewarrat, F. and Suri, R. E. and Klisic, J. and Donath, M. and Zakharov, P. and Schaub, D. and Stahel, W. A. and Talary, M. S.. (2011) Characteristics of a multisensor system for non invasive glucose monitoring with external validation and prospective evaluation. Biosensors & bioelectronics, Vol. 26, H. 9. pp. 3794-3800.

2010

Ehses, J. A. and Meier, D. T. and Wueest, S. and Rytka, J. and Boller, S. and Wielinga, P. Y. and Schraenen, A. and Lemaire, K. and Debray, S. and Van Lommel, L. and Pospisilik, J. A. and Tschopp, O. and Schultze, S. M. and Malipiero, U. and Esterbauer, H. and Ellingsgaard, H. and Rütti, S. and Schuit, F. C. and Lutz, T. A. and Böni-Schnetzler, M. and Konrad, D. and Donath, Marc Y.. (2010) Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet. Diabetologia, Vol. 53, no. 8. pp. 1795-1806.

Wueest, Stephan and Rapold, Reto A. and Schumann, Desiree M. and Rytka, Julia M. and Schildknecht, Anita and Nov, Ori and Chervonsky, Alexander V. and Rudich, Assaf and Schoenle, Eugen J. and Donath, Marc Y. and Konrad, Daniel. (2010) Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice. Journal of Clinical Investigation, Vol. 120, H. 1. pp. 191-202.

Donath, Marc Y. and Böni-Schnetzler, Marianne. (2010) IL-1 activation as a response to metabolic disturbances. Cell metabolism, Vol. 12, H. 5. pp. 427-428.

Mandrup-Poulsen, Thomas and Pickersgill, Linda and Donath, Marc Yves. (2010) Blockade of interleukin 1 in type 1 diabetes mellitus. Nature Reviews. Endocrinology, Vol. 6, no. 3. pp. 158-166.

Dinarello, Charles A. and Donath, Marc Y. and Mandrup-Poulsen, Thomas. (2010) Role of IL-1β in type 2 diabetes. Current opinion in endocrinology, diabetes & obesity, Vol. 17, no. 4. pp. 314-321.

Dinarello, Charles and Arend, William and Sims, John and Smith, Dirk and Blumberg, Hal and O'Neill, Luke and Goldbach-Mansky, Raphaela and Pizarro, Theresa and Hoffman, H. and Bufler, Philip and Nold, Marcel and Ghezzi, Pietro and Mantovani, Alberto and Garlanda, Cecilia and Boraschi, Diana and Rubartelli, Anna and Netea, Mihai and van der Meer, Jos and Joosten, Leo and Mandrup-Poulsen, Tom and Donath, Marc and Lewis, Eli and Pfeilschifter, Josef and Martin, Michael and Kracht, Michael and Muehl, H. and Novick, Daniela and Lukic, Miodrag and Conti, Bruno and Solinger, Alan and Peyman, Kelk and van de Veerdonk, Frank and Gabel, Chiristopher. (2010) IL-1 family nomenclature. Nature immunology, Vol. 11. p. 973.

Donath, Marc Y. and Böni-Schnetzler, Marianne and Ellingsgaard, Helga and Halban, Philippe A. and Ehses, Jan A.. (2010) Cytokine production by islets in health and diabetes : cellular origin, regulation and function. Trends in endocrinology and metabolism, Vol. 21, no. 5. pp. 261-267.