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Targeting inflammation in the treatment of type 2 diabetes: time to start

Donath, Marc Y.. (2014) Targeting inflammation in the treatment of type 2 diabetes: time to start. Nature Reviews. Drug Discovery, 13 (6). pp. 465-476.

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Official URL: https://edoc.unibas.ch/61704/

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Abstract

The role of inflammation in the pathogenesis of type 2 diabetes and associated complications is now well established. Several conditions that are driven by inflammatory processes are also associated with diabetes, including rheumatoid arthritis, gout, psoriasis and Crohn's disease, and various anti-inflammatory drugs have been approved or are in late stages of development for the treatment of these conditions. This review discusses the rationale for the use of some of these anti-inflammatory treatments in patients with diabetes and what we could expect from their use. Future immunomodulatory treatments may not target a specific disease, but could instead act on a dysfunctional pathway that causes several conditions associated with the metabolic syndrome.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Diabetes Research (Donath)
UniBasel Contributors:Donath, Marc
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Publisher:Nature Publishing Group
ISSN:1474-1776
e-ISSN:1474-1784
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:22 Jul 2020 11:44
Deposited On:22 Jul 2020 11:44

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