IL-1 activation as a response to metabolic disturbances

Donath, Marc Y. and Böni-Schnetzler, Marianne. (2010) IL-1 activation as a response to metabolic disturbances. Cell metabolism, Vol. 12, H. 5. pp. 427-428.

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Official URL: http://edoc.unibas.ch/dok/A6004360

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IL-1 is a major regulator of islet inflammation in type 2 diabetes. Several factors contribute to the induction of islet-derived IL-1 , including glucose, free fatty acids, and leptin. A recent report in Nature Immunology (Masters et al., 2010) identifies amyloid polypeptide as an additional enhancer of IL-1 production.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Infection Biology (Khanna)
UniBasel Contributors:Donath, Marc
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Cell Press
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:07 Dec 2012 13:03
Deposited On:07 Dec 2012 13:01

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