Items where Division is "05 Faculty of Science > Departement Biozentrum > Growth & Development"

2022

Battaglioni, Stefania and Benjamin, Don and Wälchli, Matthias and Maier, Timm and Hall, Michael N.. (2022) mTOR substrate phosphorylation in growth control. Cell, 185 (11). pp. 1814-1836.

Sauter, Nora and Sangermani, Matteo and Hug, Isabelle and Jenal, Urs and Pfohl, Thomas. (2022) Bacteria-on-a-bead: probing the hydrodynamic interplay of dynamic cell appendages during cell separation. Communications biology, 5 (1). p. 1093.

2021

Reinders, Alberto and Sellner, Benjamin and Fadel, Firas and van Berkum, Margo and Kaczmarczyk, Andreas and Ozaki, Shogo and Rueher, Johanna and Manfredi, Pablo and Sangermani, Matteo and Harms, Alexander and Perez, Camilo and Schirmer, Tilman and Jenal, Urs. (2021) Digital control of c-di-GMP in E. coli balances population-wide developmental transitions and phage sensitivity.

Santi, Isabella and Manfredi, Pablo and Jenal, Urs. (2021) The Use of Experimental Evolution to Study the Response of Pseudomonas aeruginosa to Single or Double Antibiotic Treatment. Methods in Molecular Biology, 2357. pp. 177-194.

Santi, Isabella and Manfredi, Pablo and Maffei, Enea and Egli, Adrian and Jenal, Urs. (2021) Evolution of Antibiotic Tolerance Shapes Resistance Development in Chronic Pseudomonas aeruginosa Infections. mBio, 12 (1). e03482-20.

Shyp, Viktoriya and Dubey, Badri Nath and Böhm, Raphael and Hartl, Johannes and Nesper, Jutta and Vorholt, Julia A. and Hiller, Sebastian and Schirmer, Tilman and Jenal, Urs. (2021) Reciprocal growth control by competitive binding of nucleotide second messengers to a metabolic switch in Caulobacter crescentus. Nature Microbiology, 6 (1). pp. 59-72.

Wasson, Jadiel A. and Harris, Gareth and Keppler-Ross, Sabine and Brock, Trisha J. and Dar, Abdul R. and Butcher, Rebecca A. and Fischer, Sylvia E. J. and Kagias, Konstantinos and Clardy, Jon and Zhang, Yun and Mango, Susan E.. (2021) Neuronal control of maternal provisioning in response to social cues. Science Advances, 7 (34). eabf8782.

2020

Coppine, Jérôme and Kaczmarczyk, Andreas and Petit, Kenny and Brochier, Thomas and Jenal, Urs and Hallez, Régis. (2020) Regulation of Bacterial Cell Cycle Progression by Redundant Phosphatases. Journal of Bacteriology, 202 (17). e00345-20.

Hartl, Johannes and Kiefer, Patrick and Kaczmarczyk, Andreas and Mittelviefhaus, Maximilian and Meyer, Fabian and Vonderach, Thomas and Hattendorf, Bodo and Jenal, Urs and Vorholt, Julia A.. (2020) Untargeted metabolomics links glutathione to bacterial cell cycle progression. Nature metabolism, 2 (2). pp. 153-166.

Laventie, Benoît-Joseph and Jenal, Urs. (2020) Surface Sensing and Adaptation in Bacteria. Annual review of microbiology, 74. pp. 735-760.

Rossmann, Florian M. and Hug, Isabelle and Sangermani, Matteo and Jenal, Urs and Beeby, Morgan. (2020) In situ structure of the Caulobacter crescentus flagellar motor and visualization of binding of a CheY-homolog. Molecular microbiology, 114 (3). pp. 443-453.

2018

Ganier, Olivier and Schnerch, Dominik and Oertle, Philipp and Lim, Roderick Y. H. and Plodinec, Marija and Nigg, Erich A.. (2018) Structural centrosome aberrations promote non-cell-autonomous invasiveness. The EMBO journal. e98576.

Lori, C. and Kaczmarczyk, A. and de Jong, I. and Jenal, U.. (2018) A Single-Domain Response Regulator Functions as an Integrating Hub To Coordinate General Stress Response and Development in Alphaproteobacteria. mBio, 9 (3). e00809-18.

Lori, C. and Kaczmarczyk, A. and de Jong, I. and Jenal, U.. (2018) Erratum for Lori et al., "A Single-Domain Response Regulator Functions as an Integrating Hub To Coordinate General Stress Response and Development in Alphaproteobacteria". mBio, 9 (5). e01534-18..

2017

Jenal, Urs and Reinders, Alberto and Lori, Christian. (2017) Cyclic di-GMP: second messenger extraordinaire. Nature Reviews Microbiology, 15 (5). pp. 271-284.

Schmid, Nadine and Suppiger, Angela and Steiner, Elisabeth and Pessi, Gabriella and Kaever, Volkhard and Fazli, Mustafa and Tolker-Nielsen, Tim and Jenal, Urs and Eberl, Leo. (2017) High intracellular c-di-GMP levels antagonize quorum sensing and virulence gene expression in Burkholderia cenocepacia H111. Microbiology, 163 (5). pp. 754-764.

Sedlmayer, Ferdinand and Jaeger, Tina and Jenal, Urs and Fussenegger, Martin. (2017) Quorum-Quenching Human Designer Cells for Closed-Loop Control of Pseudomonas aeruginosa Biofilms. Nano Letters, 17 (8). pp. 5043-5050.

Shi, Guojun and Somlo, Diane and Kim, Geun Hyang and Prescianotto-Baschong, Cristina and Sun, Shengyi and Beuret, Nicole and Long, Qiaoming and Rutishauser, Jonas and Arvan, Peter and Spiess, Martin and Qi, Ling. (2017) ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis. Journal of Clinical Investigation, 127 (10). pp. 3897-3912.

1 January 2016

Hengge, Regine and Galperin, Michael Y. and Ghigo, Jean-Marc and Gomelsky, Mark and Green, Jeffrey and Hughes, Kelly T. and Jenal, Urs and Landini, Paolo. (2016) Systematic nomenclature for GGDEF and EAL domain-containing Cyclic di-GMP turnover proteins of Escherichia coli. Journal of bacteriology, 198 (1). pp. 7-11.

Rotem, Or and Nesper, Jutta and Borovok, Ilya and Gorovits, Rena and Kolot, Mikhail and Pasternak, Zohar and Shin, Irina and Glatter, Timo and Pietrokovski, Shmuel and Jenal, Urs and Jurkevitch, Edouard. (2016) An extended cyclic di-GMP network in the predatory bacterium Bdellovibrio bacteriovorus. Journal of bacteriology, 198 (1). pp. 127-137.

January 2016

Hengge, Regine and Gründling, Angelika and Jenal, Urs and Ryan, Robert and Yildiz, Fitnat. (2016) Bacterial signal transduction by c-di-GMP and other nucleotide second messengers. Journal of bacteriology, 198 (1). pp. 15-26.

2016

Broder, Ursula N. and Jaeger, Tina and Jenal, Urs. (2016) LadS is a calcium-responsive kinase that induces acute-to-chronic virulence switch in Pseudomonas aeruginosa. Nature Microbiology, 2. p. 16184.

Reinders, Alberto and Hee, Chee-Seng and Ozaki, Shogo and Mazur, Adam and Boehm, Alex and Schirmer, Tilman and Jenal, Urs. (2016) Expression and Genetic Activation of Cyclic Di-GMP-Specific Phosphodiesterases in Escherichia coli. Journal of Bacteriology, 198 (3). pp. 448-462.

Valentini, Martina and Laventie, Benoît-Joseph and Moscoso, Joana and Jenal, Urs and Filloux, Alain. (2016) The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility. PLoS genetics, 12 (10). e1006354.

2015

Laventie, Benoît-Joseph and Nesper, Jutta and Ahrné, Erik and Glatter, Timo and Schmidt, Alexander and Jenal, Urs. (2015) Capture compound mass spectrometry - a powerful tool to identify novel c-di-GMP effector proteins. Journal of visualized experiments, H. 97 , e51404.

Manfredi, Pablo and Jenal, Urs. (2015) Bacteria in the CF Lung: Isolation Drives Diversity. Cell host & microbe, Vol. 18, H. 3. pp. 268-269.

2014

Fei, Na and Häussinger, Daniel and Blümli, Seraina and Laventie, Benoît-Joseph and Bizzini, Lorenzo D. and Zimmermann, Kaspar and Jenal, Urs and Gillingham, Dennis. (2014) Catalytic carbene transfer allows the direct customization of cyclic purine dinucleotides. Chemical Communications, 50 (62). pp. 8499-8502.

Fumeaux, Coralie and Radhakrishnan, Sunish Kumar and Ardissone, Silvia and Théraulaz, Laurence and Frandi, Antonio and Martins, Daniel and Nesper, Jutta and Abel, Sören and Jenal, Urs and Viollier, Patrick H.. (2014) Cell cycle transition from S-phase to G1 in Caulobacter is mediated by ancestral virulence regulators. Nature Communications, 5. p. 4081.

Ozaki, Shogo and Schalch-Moser, Annina and Zumthor, Ludwig and Manfredi, Pablo and Ebbensgaard, Anna and Schirmer, Tilman and Jenal, Urs. (2014) Activation and polar sequestration of PopA, a c-di-GMP effector protein involved in Caulobacter crescentus cell cycle control. Molecular Microbiology, 94 (3). pp. 580-594.

2013

Yang, Q. and Nausch, L. W. and Martin, G. and Keller, W. and Doublié, S.. (2013) Crystal structure of human poly(A) polymerase gamma reveals a conserved catalytic core for canonical poly(A) polymerases. Journal of Molecular Biology, 426 (1). pp. 43-50.

2012

Gruber, Andreas R. and Martin, Georges and Keller, Walter and Zavolan, Mihaela. (2012) Cleavage factor Im is a key regulator of 3' UTR length. RNA Biology, 9 (12). pp. 1405-1412.

2010

Martin, G. and Ostareck-Lederer, A. and Chari, A. and Neuenkirchen, N. and Dettwiler, S. and Blank, D. and Rüegsegger, U. and Fischer, U. and Keller, W.. (2010) Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I. RNA, Vol. 16. pp. 1646-1659.

2008

Coseno, M. and Martin., G. and Berger, C. and Gilmartin, G. and Keller, W. and Doublié, S.. (2008) Crystal structure of the 25 kDa subunit of human cleavage factor Im. Nucleic acids research, Vol. 36, H. 10. pp. 3474-3483.

Garas, M. and Dichtl, B. and Keller, W.. (2008) The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis. Rna, Vol. 14, H. 12. pp. 2671-2684.

Martin, Georges and Doublié, Sylvie and Keller, Walter. (2008) Determinants of substrate specificity in RNA-dependent nucleotidyl transferases. Biochimica et Biophysica Acta, 1779 (4). pp. 206-216.

2007

Danckwardt, S. and Kaufmann, I. and Gentzel, M. and Foerstner, K. U. and Gantzert, A. -S. and Gehring, N. H. and Neu-Yilik, G. and Bork, P. and Keller, W. and Wilm, M. and Hentze, M. W. and Kulozik, A. E.. (2007) Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals. The EMBO Journal, 26 (11). pp. 2658-2669.

Martin, G. and Keller, W.. (2007) RNA-specific ribonucleotidyl transferases. Rna, Vol. 13, H. 11. pp. 1834-1849.

2006

Kyburz, A. and Friedlein, A. and Langen, H. and Keller, W.. (2006) Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3' end processing and splicing. Molecular Cell, 23 (2). pp. 195-205.

Millevoi, S. and Loulergue, C. and Dettwiler, S. and Karaa, S. Z. and Keller, W. and Antoniou, M. and Vagner, S.. (2006) An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries. The EMBO Journal, 25 (20). pp. 4854-4864.

2005

Ingham, R. J. and Colwill, K. and Howard, C. and Dettwiler, S. and Lim, C. S. H. and Yu, J. and Hersi, K. and Raaijmakers, J. and Gish, G. and Mbamalu, G. and Taylor, L. and Yeung, B. and Vassilovski, G. and Amin, M. and Chen, F. and Matskova, L. and Winberg, G. and Ernberg, I. and Linding, R. and O'Donnell, P. and Starostine, A. and Keller, W. and Metalnikov, P. and Stark, C. and Pawson, T.. (2005) WW domains provide a platform for the assembly of multiprotein networks. Molecular and Cellular Biology, 25 (16). pp. 7092-7106.

Vanacova, S. and Wolf, J. and Martin, G. and Blank, D. and Dettwiler, S. and Friedlein, A. and Langen, H. and Keith, G. and Keller, W.. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biology, Vol. 3, H. 6 , e189.

2004

Dettwiler, S. and Aringhieri, C. and Cardinale, S. and Keller, W. and Barabino, S. M. L.. (2004) Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. Journal of biological chemistry, 279 (34). pp. 35788-35797.

Dichtl, B. and Aasland, R. and Keller, W.. (2004) Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation. RNA, Vol. 10, H. 6. pp. 965-977.

Kaufmann, I. and Martin, G. and Friedlein, A. and Langen, H. and Keller, W.. (2004) Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. The EMBO Journal, 23 (3). pp. 616-626.

Martin, G. and Keller, W.. (2004) Sequence motifs that distinguish ATP(CTP) : tRNA nucleotidyl transferases from eubacterial poly(A) polymerases. RNA, Vol. 10, H. 6. pp. 899-906.

Martin, G. and Möglich, A. and Keller, W. and Doublié., S.. (2004) Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase. Journal of Molecular Biology, 341 (4). pp. 911-925.

2003

Kyburz, A. and Sadowski, M. and Dichtl, B. and Keller, W.. (2003) The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation. Nucleic acids research, Vol. 31, H. 14. pp. 3936-3945.

Sadowski, M. and Dichtl, B. and Hübner, W. and Keller, W.. (2003) Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination. The EMBO Journal, 22 (9). pp. 2167-2177.

2002

Dichtl, B. and Blank, D. and Ohnacker, M. and Friedlein, A. and Roeder, D. and Langen, H. and Keller, W.. (2002) A role for SSU72 in balancing RNA polymerase II transcription elongation and termination. Molecular Cell, 10 (5). pp. 1139-1150.

Dichtl, B. and Blank, D. and Sadowski, M. and Hübner, W. and Weiser, S. and Keller, W.. (2002) Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination. The EMBO Journal, 21 (15). pp. 4125-4135.

Morlando, M. and Greco, P. and Dichtl, B. and Fatica, A. and Keller, W. and Bozzoni, I.. (2002) Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation. Molecular and Cellular Biology, 22 (5). pp. 1379-1389.

Schaub, M. and Keller, W.. (2002) RNA editing by adenosine deaminases generates RNA and protein diversity. Biochimie, 84 (8). pp. 791-803.

Wolf, J. and Gerber, A. P. and Keller, W.. (2002) tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli. The EMBO Journal, 21 (14). pp. 3841-3851.

2001

Dichtl, B. and Keller, W.. (2001) Recognition of polyadenylation sites in yeast pre-mRNAs by cleavage and polyadenylation factor. The EMBO Journal, 20 (12). pp. 3197-3209.

Gerber, A. P. and Keller, W.. (2001) RNA editing by base deamination : more enzymes, more targets, new mysteries. Trends in Biochemical Sciences, 26 (6). pp. 376-384.

2000

De Vries, H. and Rüegsegger, U. and Hübner, W. and Friedlein, A. and Langen, H. and Keller, W.. (2000) Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. The EMBO Journal, 19 (21). pp. 5895-5904.

Fahrenkrog, B. and Hubner, W. and Mandinova, A. and Pante, N. and Keller, W. and Aebi, U.. (2000) The yeast nucleoporin Nup53p specifically interacts with Nic96p and is directly involved in nuclear protein import. Molecular and Cellular Biology, 11 (11). pp. 3885-3896.

Keegan, L. P. and Gerber, A. P. and Brindle, J. and Leemans, R. and Gallo, A. and Keller, W. and O'Connell, M. A.. (2000) The properties of a tRNA-specific adenosine deaminase from Drosophila melanogaster support an evolutionary link between pre-mRNA editing and tRNA modification. Molecular and Cellular Biology, 20 (3). pp. 825-833.

Martin, G. and Keller, W. and Doublié, S.. (2000) Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP. The EMBO Journal, 19 (16). pp. 4193-4203.

Ohnacker, M. and Barabino, S. and Preker, P. J. and Keller, W.. (2000) The WD-repeat protein pfs2p bridges two essential factors within the yeast pre-mRNA 3'-end-processing complex. The EMBO Journal, 19 (1). pp. 37-47.

Vagner, S. and Rüegsegger, U. and Gunderson, S. I. and Keller, W. and Mattaj, I. W.. (2000) Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP. Rna, Vol. 6, H. 2. pp. 178-188.

1999

Barabino, S. M. and Keller, W.. (1999) Last but not least : regulated poly(A) tail formation. Cell, 99 (1). pp. 9-11.

Gerber, A. P. and Keller, W.. (1999) An adenosine deaminase that generates inosine at the wobble position of tRNAs. Science, 286 (5442). pp. 1146-1149.

Keller, W. and Wolf, J. and Gerber, A.. (1999) Editing of messenger RNA precursors and of tRNAs by adenosine to inosine conversion. FEBS Letters, 452 (1-2). pp. 71-76.

Martin, G. and Jenö, P. and Keller, W.. (1999) Mapping of ATP binding regions in poly(A) polymerases by photoaffinity labeling and by mutational analysis identifies a domain conserved in many nucleotidyltransferases. Protein Science, 8 (11). pp. 2380-2391.