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2015

Bocelli-Tyndall, C. and Trella, E. and Frachet, A. and Zajac, P. and Pfaff, D. and Geurts, J. and Heiler, S. and Barbero, A. and Mumme, M. and Resink, T. J. and Schaeren, S. and Spagnoli, G. C. and Tyndall, A.. (2015) FGF2 induces RANKL gene expression as well as IL1beta regulated MHC class II in human bone marrow-derived mesenchymal progenitor stromal cells. Annals of the rheumatic diseases, Vol. 74, H. 1. pp. 260-266.

Sesia, Sergio B. and Duhr, Ralph and Medeiros da Cunha, Carolina and Todorov, Atanas and Schaeren, Stefan and Padovan, Elisabetta and Spagnoli, Giulio and Martin, Ivan and Barbero, Andrea. (2015) Anti-inflammatory/tissue repair macrophages enhance the cartilage-forming capacity of human bone marrow-derived mesenchymal stromal cells. Journal of cellular physiology, 230 (6). pp. 1258-1269.

2014

Mele, V. and Muraro, M. G. and Calabrese, D. and Pfaff, D. and Amatruda, N. and Amicarella, F. and Kvinlaug, B. and Bocelli-Tyndall, C. and Martin, I. and Resink, T. J. and Heberer, M. and Oertli, D. and Terracciano, L. and Spagnoli, G. C. and Iezzi, G.. (2014) Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-beta. International journal of cancer, Vol. 134, H. 11. pp. 2583-2594.

Müller, P. and Martin, K. and Theurich, S. and Schreiner, J. and Savic, S. and Terszowski, G. and Lardinois, D. and Heinzelmann-Schwarz, V. A. and Schlaak, M. and Kvasnicka, H. M. and Spagnoli, G. and Dirnhofer, S. and Speiser, D. E. and von Bergwelt-Baildon, M. and Zippelius, A.. (2014) Microtubule-depolymerizing agents used in antibody-drug conjugates induce antitumor immunity by stimulation of dendritic cells. Cancer Immunology Research, 2 (8). pp. 741-755.

2013

Philippova, M. and Pfaff, D. and Kyriakakis, E. and Buechner, S. A. and Iezzi, G. and Spagnoli, G. C. and Schoenenberger, A. W. and Erne, P. and Resink, T. J.. (2013) T-cadherin loss promotes experimental metastasis of squamous cell carcinoma. European journal of cancer, Vol. 49, H. 8. pp. 2048-2058.

Hudolin, T. and Kastelan, Z. and Ilic, I. and Levarda-Hudolin, K. and Basic-Jukic, N. and Rieken, M. and Spagnoli, G. C. and Juretic, A. and Mengus, C.. (2013) Immunohistochemical analysis of the expression of MAGE-A and NY-ESO-1 cancer/testis antigens in diffuse large B-cell testicular lymphoma. Journal of translational medicine, Vol. 11 , 123. p. 123.

Hirt, Christian and Eppenberger-Castori, Serenella and Sconocchia, Giuseppe and Iezzi, Giandomenica and Tornillo, Luigi and Terracciano, Luigi and Spagnoli, Giulio C. and Droeser, Raoul A.. (2013) Colorectal carcinoma infiltration by myeloperoxidase-expressing neutrophil granulocytes is associated with favorable prognosis. OncoImmunology, Vol. 2, H. 10 , e25990.

Droeser, R. A. and Hirt, C. and Viehl, C. T. and Frey, D. M. and Nebiker, C. and Huber, X. and Zlobec, I. and Eppenberger-Castori, S. and Tzankov, A. and Rosso, R. and Zuber, M. and Muraro, M. G. and Amicarella, F. and Cremonesi, E. and Heberer, M. and Iezzi, G. and Lugli, A. and Terracciano, L. and Sconocchia, G. and Oertli, D. and Spagnoli, G. C. and Tornillo, L.. (2013) Clinical impact of programmed cell death ligand 1 expression in colorectal cancer. European journal of cancer, Vol. 49, H. 9. pp. 2233-2242.

Droeser, R. A. and Hirt, C. and Eppenberger-Castori, S. and Zlobec, I. and Viehl, C. T. and Frey, D. M. and Nebiker, C. A. and Rosso, R. and Zuber, M. and Amicarella, F. and Iezzi, G. and Sconocchia, G. and Heberer, M. and Lugli, A. and Tornillo, L. and Oertli, D. and Terracciano, L. and Spagnoli, G. C.. (2013) High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor. PLoS ONE, Vol. 8, H. 5 , e64814.

Bhattacharjee, M. and Schultz-Thater, E. and Trella, E. and Miot, S. and Das, S. and Loparic, M. and Ray, A. R. and Martin, I. and Spagnoli, G. C. and Ghosh, S.. (2013) The role of 3D structure and protein conformation on the innate and adaptive immune responses to silk-based biomaterials. Biomaterials, Vol. 34, no. 33. pp. 8161-8171.

Le Magnen, C. and Bubendorf, L. and Rentsch, C. A. and Mengus, C. and Gsponer, J. and Zellweger, T. and Rieken, M. and Thalmann, G. N. and Cecchini, M. G. and Germann, M. and Bachmann, A. and Wyler, S. and Heberer, M. and Spagnoli, G. C.. (2013) Characterization and clinical relevance of ALDHbright populations in prostate cancer. Clinical cancer research, Vol. 19, no. 19. pp. 5361-5371.

Mengus, C. and Schultz-Thater, E. and Coulot, J. and Kastelan, Z. and Goluza, E. and Coric, M. and Spagnoli, G. C. and Hudolin, T.. (2013) MAGE-A10 cancer/testis antigen is highly expressed in high-grade non-muscle-invasive bladder carcinomas. International journal of cancer, Vol. 132, H. 10. pp. 2459-2463.

Le Magnen, C. and Bubendorf, L. and Ruiz, C. and Zlobec, I. and Bachmann, A. and Heberer, M. and Spagnoli, G. C. and Wyler, S. and Mengus, C.. (2013) Klf4 transcription factor is expressed in the cytoplasm of prostate cancer cells. European journal of cancer, Vol. 49, H. 4. pp. 955-963.

2012

Sconocchia, G. and Arriga, R. and Tornillo, L. and Terracciano, L. and Ferrone, S. and Spagnoli, G. C.. (2012) Melanoma cells inhibit NK cell functions. Cancer research, Vol. 72, H. 20. pp. 5428-5429.

Muraro, Manuele Giuseppe and Mele, Valentina and Däster, Silvio and Han, Junyi and Heberer, Michael and Cesare Spagnoli, Giulio and Iezzi, Giandomenica. (2012) CD133+, CD166+CD44+, and CD24+CD44+ phenotypes fail to reliably identify cell populations with cancer stem cell functional features in established human colorectal cancer cell lines. Stem cells translational medicine, Vol. 1, H. 8. pp. 592-603.

Montoro, J. R. and Mamede, R. C. and Neder Serafini, L. and Saggioro, F. P. and Figueiredo, D. L. and Silva, W. A. and Jr., and Jungbluth, A. A. and Spagnoli, G. C. and Zago, M. A.. (2012) Expression of cancer-testis antigens MAGE-A4 and MAGE-C1 in oral squamous cell carcinoma. Head & neck, Vol. 34, H. 8. pp. 1123-1128.

Moeller, I. and Spagnoli, G. C. and Finke, J. and Veelken, H. and Houet, L.. (2012) Uptake routes of tumor-antigen MAGE-A3 by dendritic cells determine priming of naive T-cell subtypes. Cancer immunology, immunotherapy, Vol. 61, H. 11. pp. 2079-2090.

Badovinac-Crnjevic, T. and Spagnoli, G. and Juretic, A. and Jakic-Razumovic, J. and Podolski, P. and Saric, N.. (2012) Erratum to: High expression of MAGE-A10 cancer-testis antigen in triple-negative breast cancer. Medical oncology, Vol. 29, H. 3. p. 1592.

Kuhl, S. and Deyhle, H. and Zimmerli, M. and Spagnoli, G. and Beckmann, F. and Muller, B. and Filippi, A.. (2012) Cracks in dentin and enamel after cryopreservation. Oral surgery, oral medicine, oral pathology, oral radiology, Vol. 113, H. 2 , e5-e10.

Droeser, R. and Zlobec, I. and Kilic, E. and Guth, U. and Heberer, M. and Spagnoli, G. and Oertli, D. and Tapia, C.. (2012) Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+ tumor infiltrating lymphocytes in ductal and lobular breast cancers. BMC cancer, Vol. 12 , 134.

Raafat, N. and Sadowski-Cron, C. and Mengus, C. and Heberer, M. and Spagnoli, G. C. and Zajac, P.. (2012) Preventing vaccinia virus class-I epitopes presentation by HSV-ICP47 enhances the immunogenicity of a TAP-independent cancer vaccine epitope. International journal of cancer, Vol. 131, H. 5 , S. E659-E669.

Sais, G. and Wyler, S. and Hudolin, T. and Banzola, I. and Mengus, C. and Bubendorf, L. and Wild, P. J. and Hirsch, H. H. and Sulser, T. and Spagnoli, G. C. and Provenzano, M.. (2012) Differential patterns of large tumor antigen-specific immune responsiveness in patients with BK polyomavirus-positive prostate cancer or benign prostatic hyperplasia. Journal of virology, Vol. 86, H. 16. pp. 8461-8471.

Badovinac Črnjević, Tanja and Tanja, Badovinac Črnjević and Spagnoli, Giulio and Giulio, Spagnoli and Juretić, Antonio and Antonio, Juretić and Jakić-Razumović, Jasminka and Jasminka, Jakić-Razumović and Podolski, Paula and Paula, Podolski and Šarić, Nera and Nera, Šarić. (2012) High expression of MAGE-A10 cancer-testis antigen in triple-negative breast cancer. Medical oncology, Vol. 29, H. 3. pp. 1586-1591.

2011

Pfaff, Dennis and Philippova, Maria and Kyriakakis, Emmanouil and Maslova, Kseniya and Rupp, Katharina and Buechner, Stanislaw A. and Iezzi, Giandomenica and Spagnoli, Giulio C. and Erne, Paul and Resink, Therese J.. (2011) Paradoxical effects of T-cadherin on squamous cell carcinoma : up- and down-regulation increase xenograft growth by distinct mechanisms. The journal of pathology, Vol. 225, no. 4. pp. 512-524.

Matkovi?, Bozica and Jureti?, Antonio and Spagnoli, Giulio C. and Separovi?, Viktor and Gamulin, Marija and Separovi?, Robert and Sari?, Nera and Basi?-Koreti?, Martina and Novosel, Irena and Kruslin, Bozo. (2011) Expression of MAGE-A and NY-ESO-1 cancer/testis antigens in medullary breast cancer : retrospective immunohistochemical study. Croatian medical journal, Vol. 52, H. 2. pp. 171-177.

Figueiredo, David L. A. and Mamede, Rui C. M. and Spagnoli, Giulio C. and Silva, Wilson A. and Zago, Marco and Neder, Luciano and Jungbluth, Achim A. and Saggioro, Fabiano P.. (2011) High expression of cancer testis antigens MAGE-A, MAGE-C1/CT7, MAGE-C2/CT10, NY-ESO-1, and gage in advanced squamous cell carcinoma of the larynx. Head & neck, Vol. 33, H. 5. pp. 702-707.

Adams, S. and Greeder, L. and Reich, E. and Shao, Y. and Fosina, D. and Hanson, N. and Tassello, J. and Singh, B. and Spagnoli, G. C. and Demaria, S. and Jungbluth, A. A.. (2011) Expression of cancer testis antigens in human BRCA-associated breast cancers : potential targets for immunoprevention? Cancer immunology, immunotherapy, Vol. 60, H. 7. pp. 999-1007.

Curigliano, G. and Viale, G. and Ghioni, M. and Jungbluth, A. A. and Bagnardi, V. and Spagnoli, G. C. and Neville, A. M. and Nolè, F. and Rotmensz, N. and Goldhirsch, A.. (2011) Cancer-testis antigen expression in triple-negative breast cancer. Annals of oncology, Vol. 22, H. 1. pp. 98-103.

Schultz-Thater, E. and Piscuoglio, S. and Iezzi, G. and Le Magnen, C. and Zajac, P. and Carafa, V. and Terracciano, L. and Tornillo, L. and Spagnoli, G. C.. (2011) MAGE-A10 is a nuclear protein frequently expressed in high percentages of tumor cells in lung, skin and urothelial malignancies. International journal of cancer, Vol. 129, H. 5. pp. 1137-1148.

Sconocchia, Giuseppe and Zlobec, Inti and Lugli, Alessandro and Calabrese, Diego and Iezzi, Giandomenica and Karamitopoulou, Eva and Patsouris, Efstratios S. and Peros, George and Horcic, Milo and Tornillo, Luigi and Zuber, Markus and Droeser, Raoul and Muraro, Manuele G. and Mengus, Chantal and Oertli, Daniel and Ferrone, Soldano and Terracciano, Luigi and Spagnoli, Giulio C.. (2011) Tumor infiltration by FcγRIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma. International Journal of Cancer, 128 (11). pp. 2663-2672.

Mengus, C. and Le Magnen, C. and Trella, E. and Yousef, K. and Bubendorf, L. and Provenzano, M. and Bachmann, A. and Heberer, M. and Spagnoli, G. C. and Wyler, S.. (2011) Elevated levels of circulating IL-7 and IL-15 in patients with early stage prostate cancer. Journal of translational medicine, Vol. 9 , 162. p. 162.

2010

Adamina, Michel and Rosenthal, Rachel and Weber, Walter P. and Frey, Daniel M. and Viehl, Carsten T. and Bolli, Martin and Huegli, Rolf W. and Jacob, Augustinus L. and Heberer, Michael and Oertli, Daniel and Marti, Walter and Spagnoli, Giulio C. and Zajac, Paul. (2010) Intranodal immunization with a vaccinia virus encoding multiple antigenic epitopes and costimulatory molecules in metastatic melanoma. Molecular therapy, Vol. 18, H. 3. pp. 651-659.

Lugli, A. and Iezzi, G. and Hostettler, I. and Muraro, M. G. and Mele, V. and Tornillo, L. and Carafa, V. and Spagnoli, G. and Terracciano, L. and Zlobec, I.. (2010) Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer. British journal of cancer, Vol. 103, no. 3. pp. 382-390.

Pastorcic-Grgic, Marija and Sarcevic, Bozena and Dosen, Danijel and Juretic, Antonio and Spagnoli, Giulio C. and Grgic, Marko. (2010) Prognostic value of MAGE-A and NY-ESO-1 expression in pharyngeal cancer. Head & neck, Vol. 32, H. 9. pp. 1178-1184.

Vukcevic, Mirko and Zorzato, Francesco and Spagnoli, Giulio and Treves, Susan. (2010) Frequent calcium oscillations lead to NFAT activation in human immature dendritic cells. Journal of Biological Chemistry, 285 (21). pp. 16003-16011.

Schatton, Tobias and Schütte, Ute and Frank, Natasha Y. and Zhan, Qian and Hoerning, André and Robles, Susanne C. and Zhou, Jun and Hodi, F. Stephen and Spagnoli, Giulio C. and Murphy, George F. and Frank, Markus H.. (2010) Modulation of T-cell activation by malignant melanoma initiating cells. Cancer research, Vol. 70,2. pp. 697-708.

Zlobec, Inti and Karamitopoulou, Eva and Terracciano, Luigi and Piscuoglio, Salvatore and Iezzi, Giandomenica and Muraro, Manuele Giuseppe and Spagnoli, Giulio and Baker, Kristi and Tzankov, Alexandar and Lugli, Alessandro. (2010) TIA-1 cytotoxic granule-associated RNA binding protein improves the prognostic performance of CD8 in mismatch repair-proficient colorectal cancer. PLoS ONE, Vol. 5, H. 12 , e14282.

Bocelli-Tyndall, Chiara and Zajac, Paul and Di Maggio, Nunzia and Trella, Emanuele and Benvenuto, Federica and Iezzi, Giandomenica and Scherberich, Arnaud and Barbero, Andrea and Schaeren, Stefan and Pistoia, Vito and Spagnoli, Giulio and Vukcevic, Mirko and Martin, Ivan and Tyndall, Alan. (2010) Fibroblast growth factor 2 and platelet-derived growth factor, but not platelet lysate, induce proliferation-dependent, functional class II major histocompatibility complex antigen in human mesenchymal stem cells. Arthritis & Rheumatism, 62 (12). pp. 3815-3825.

Spagnoli, Giulio C. and Ebrahimi, Marzieh and Iezzi, Giandomenica and Mengus, Chantal and Zajac, Paul. (2010) Contemporary immunotherapy of solid tumors : from tumor-associated antigens to combination treatments. Current opinion in drug discovery & development, Vol. 13, H. 2. pp. 184-192.

2009

Provenzano, Maurizio and Sais, Giovanni and Bracci, Laura and Egli, Adrian and Anselmi, Maurizio and Viehl, Carsten T. and Schaub, Stefan and Hirsch, Hans H. and Stroncek, David F. and Marincola, Francesco M. and Spagnoli, Giulio C.. (2009) A HCMV pp65 polypeptide promotes the expansion of CD4+ and CD8+ T cells across a wide range of HLA specificities. Journal of cellular and molecular medicine : an international journal, Vol. 13. pp. 2131-2147.

Sconocchia, Giuseppe and Spagnoli, Giulio Cesare and Del Principe, Domenico and Ferrone, Soldano and Anselmi, Maurizio and Wongsena, Wachanan and Cervelli, Valerio and Schultz-Thater, Elke and Wyler, Stephen and Carafa, Vincenza and Moch, Holger and Terracciano, Luigi and Tornillo, Luigi. (2009) Defective infiltration of natural killer cells in MICA/B-positive renal cell carcinoma involves beta(2)-integrin-mediated interaction. Neoplasia, Vol. 11. pp. 662-671.

Provenzano, Maurizio and Spagnoli, Giulio C.. (2009) T cell epitope-mapping by cytokine gene expression assay. Methods in Molecular Biology, Vol. 514. pp. 107-118.

Bocelli-Tyndall, C. and Bracci, L. and Schaeren, S. and Feder-Mengus, C. and Barbero, A. and Tyndall, A. and Spagnoli, G. C.. (2009) Human bone marrow mesenchymal stem cells and chondrocytes promote and/or suppress the in vitro proliferation of lymphocytes stimulated by interleukins 2, 7 and 15. Annals of the rheumatic diseases : ARD, Vol. 68. pp. 1352-1359.

Rosenthal, Rachel and Groeper, Célia and Bracci, Laura and Adamina, Michel and Feder-Mengus, Chantal and Zajac, Paul and Iezzi, Giandomenica and Bolli, Martin and Weber, Walter P. and Frey, Daniel M. and von Holzen, Urs and Oertli, Daniel and Heberer, Michael and Spagnoli, Giulio C.. (2009) Differential responsiveness to IL-2, IL-7, and IL-15 common receptor gamma chain cytokines by antigen-specific peripheral blood naive or memory cytotoxic CD8+ T cells from healthy donors and melanoma patients. Journal of immunotherapy, Vol. 32. pp. 252-261.

Lugli, A. and Karamitopoulou, E. and Panayiotides, I. and Karakitsos, P. and Rallis, G. and Peros, G. and Iezzi, G. and Spagnoli, G. and Bihl, M. and Terracciano, L. and Zlobec, I.. (2009) CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer. British journal of cancer : the clinical and scientific journal of The Cancer Research Campaign : BJC, Vol. 101. pp. 1382-1392.

2008

Feder-Mengus, C. and Ghosh, S. and Reschner, A. and Martin, I. and Spagnoli, G. C.. (2008) New dimensions in tumor immunology : what does 3D culture reveal? Trends in molecular medicine, 14 (8). pp. 333-340.

Feder-Mengus, C. and Wyler, S. and Hudolin, T. and Ruszat, R. and Bubendorf, L. and Chiarugi, A. and Pittelli, M. and Weber, W. P. and Bachmann, A. and Gasser, T. C. and Sulser, T. and Heberer, M. and Spagnoli, G. C. and Provenzano, M.. (2008) High expression of indoleamine 2,3-dioxygenase gene in prostate cancer. European journal of cancer, Vol. 44. pp. 2266-2675.

Adamina, M. and Weber, W. P. and Rosenthal, R. and Schumacher, R. and Zajac, P. and Guller, U. and Frey, D. M. and Oertli, D. and Zuber, M. and Heberer, M. and Spagnoli, G. C.. (2008) Heterologous prime-boost immunotherapy of melanoma patients with Influenza virosomes, and recombinant Vaccinia virus encoding 5 melanoma epitopes and 3 co-stimulatory molecules : a multi-centre phase I/II open labeled clinical trial. Contemp Clin Trials, Vol. 29. pp. 165-181.

Perez, D. and Herrmann, T. and Jungbluth, A. A. and Samartzis, P. and Spagnoli, G. and Demartines, N. and Clavien, P. A. and Marino, S. and Seifert, B. and Jaeger, D.. (2008) Cancer testis antigen expression in gastrointestinal stromal tumors : new markers for early recurrence. International journal of cancer, Vol. 123, H. 7. pp. 1551-1555.

Vukcevic, M. and Spagnoli, G. C. and Iezzi, G. and Zorzato, F. and Treves, S.. (2008) Ryanodine receptor activation by Cav1.2 Is involved in dendritic cell major histocompatibility complex class II urface expression. Journal of Biological Chemistry, 283. pp. 34913-34922.

Napoletano, C. and Bellati, F. and Tarquini, E. and Tomao, F. and Taurino, F. and Spagnoli, G. and Rughetti, A. and Muzii, L. and Nuti, M. and Benedetti Panici, P.. (2008) MAGE-A and NY-ESO-1 expression in cervical cancer : prognostic factors and effects of chemotherapy. American journal of obstetrics and gynecology, Vol. 198, H. 1 , S. 99.e1-99.e7.

Bracci, L. and Schumacher, R. and Provenzano, M. and Adamina, M. and Rosenthal, R. and Groeper, C. and Zajac, P. and Iezzi, G. and Proietti, E. and Belardelli, F. and Spagnoli, G. C.. (2008) Efficient stimulation of T cell responses by human IFN-alpha-induced dendritic cells does not require Toll-like receptor triggering. Journal of immunotherapy, Vol. 31, H. 5. pp. 466-474.

Schultz-Thater, E. and Frey, D. M. and Margelli, D. and Raafat, N. and Feder-Mengus, C. and Spagnoli, G. C. and Zajac, P.. (2008) Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR : a versatile monitoring and discovery tool. Journal of translational medicine, Vol. 6. p. 58.

Cavazza, A. and Marini, M. and Spagnoli, G. C. and Giorgio Roda, L.. (2008) Positive and negative modulation of peptidases by pro-inflammatory cytokines. Peptides, Vol. 29, H. 1. pp. 1974-1981.

Rosenthal, Rachel and Viehl, Carsten T. and Guller, Ulrich and Weber, Walter P. and Adamina, Michel and Spagnoli, Giulio C. and Heberer, Michael and Zuber, Markus. (2008) Active specific immunotherapy phase III trials for malignant melanoma : systematic analysis and critical appraisal. Journal of the American College of Surgeons, Vol. 207, H. 1. pp. 95-105.

2007

Ghosh, Sourabh and Josh, Manjunath B. and Ivanov, Danila and Feder-Mengus, Chantal and Spagnoli, Giulio C. and Martin, Ivan and Erne, Paul and Resink, Therese J.. (2007) Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: A role for T-cadherin in tumor angiogenesis. FEBS Letters, 581 (23). pp. 4523-4528.

Bracci, L. and Vukcevic, M. and Spagnoli, G. and Ducreux, S. and Zorzato, F. and Treves, S.. (2007) Ca2+ signaling through ryanodine receptor 1 enhances maturation and activation of human dendritic cells. Journal of Cell Science, 120 (13). pp. 2232-2240.