Items where Division is "03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Molecular Immune Regulation (Jeker)"

2023

Devaux, Anna. Engineering safe mutations to protect cells from antibody-based targeted therapy. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

2017

Navarini, Alexander A. and Hruz, Petr and Berger, Christoph T. and Hou, Tie Zheng and Schwab, Charlotte and Gabrysch, Annemarie and Higgins, Rebecca and Frede, Natalie and Padberg Sgier, Barbara-Christina and Kämpe, Olle and Burgener, Anne-Valérie and Marquardsen, Florian and Baldin, Fabian and Bigler, Marc and Kistner, Anne and Jauch, Annaise and Bignucolo, Olivier and Meyer, Benedikt and Meienberg, Fabian and Mehling, Matthias and Jeker, Lukas T. and Heijnen, Ingmar and Daikeler, Thomas D. and Gebbers, Jan-Olaf and Grimbacher, Bodo and Sansom, David M. and Jeker, Raphael and Hess, Christoph and Recher, Mike. (2017) Vedolizumab as a successful treatment of CTLA-4-associated autoimmune enterocolitis. Journal Of Allergy And Clinical Immunology, 139 (3). pp. 1043-1046e5.

2016

Pua, H. H. and Steiner, D. F. and Patel, S. and Gonzalez, J. R. and Ortiz-Carpena, J. F. and Kageyama, R. and Chiou, N. T. and Gallman, A. and de Kouchkovsky, D. and Jeker, L. T. and McManus, M. T. and Erle, D. J. and Ansel, K. M.. (2016) MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production. Immunity, 44 (4). pp. 821-832.

2015

Barthlott, Thomas and Bosch, Angela J. and Berkemeier, Caroline and Nogales-Cadenas, Rubén and Jeker, Lukas T. and Keller, Marcel P. and Pascual-Montano, Alberto and Hollander, Georg A.. (2015) A subpopulation of CD103(pos) ICOS(pos) Treg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stage. European Journal of Immunology, 45 (6). pp. 1760-1771.

Jeker, L. T. and Marone, R.. (2015) Targeting microRNAs for immunomodulation. Current Opinion in Pharmacology, 23. pp. 25-31.

Khan, I. S. and Park, C. Y. and Mavropoulos, A. and Shariat, N. and Pollack, J. L. and Barczak, A. J. and Erle, D. J. and McManus, M. T. and Anderson, M. S. and Jeker, L. T.. (2015) Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells. PLoS ONE, 10 (8). e0135440.

2014

Khan, Imran S. and Taniguchi, Ruth T. and Fasano, Kayla J. and Anderson, Mark S. and Jeker, Lukas T.. (2014) Canonical microRNAs in thymic epithelial cells promote central tolerance. European Journal of Immunology, 44 (5). pp. 1313-1319.

2013

Baumjohann, Dirk and Kageyama, Robin and Clingan, Jonathan M. and Morar, Malika M. and Patel, Sana and de Kouchkovsky, Dimitri and Bannard, Oliver and Bluestone, Jeffrey A. and Matloubian, Mehrdad and Ansel, K. Mark and Jeker, Lukas T.. (2013) The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression. Nature Immunology, 14 (8). pp. 840-848.

Jeker, Lukas T. and Bluestone, Jeffrey A.. (2013) MicroRNA regulation of T-cell differentiation and function. Immunological Reviews, 253 (1). pp. 65-81.

Jeker, Lukas T. and Zhou, Xuyu and Blelloch, Robert and Bluestone, Jeffrey A.. (2013) DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability. PLoS ONE, 8 (5). e66282.

de Kouchkovsky, Dimitri and Esensten, Jonathan H. and Rosenthal, Wendy L. and Morar, Malika M. and Bluestone, Jeffrey A. and Jeker, Lukas T.. (2013) microRNA-17-92 regulates IL-10 production by regulatory T cells and control of experimental autoimmune encephalomyelitis. Journal of Immunology, 191 (4). pp. 1594-1605.

2012

Jeker, Lukas T. and Bour-Jordan, Hélène and Bluestone, Jeffrey A.. (2012) Breakdown in peripheral tolerance in type 1 diabetes in mice and humans. Cold Spring Harbor Perspectives in Medicine, 2 (3). a007807.

Jeker, Lukas T. and Zhou, Xuyu and Gershberg, Kseniya and de Kouchkovsky, Dimitri and Morar, Malika M. and Stadthagen, Gustavo and Lund, Anders H. and Bluestone, Jeffrey A.. (2012) MicroRNA 10a marks regulatory T cells. PLoS ONE, 7 (5). e36684.

Park, Chong Yon and Jeker, Lukas T. and Carver-Moore, Karen and Oh, Alyssia and Liu, Huey Jiin and Cameron, Rachel and Richards, Hunter and Li, Zhongmei and Adler, David and Yoshinaga, Yuko and Martinez, Maria and Nefadov, Michael and Abbas, Abul K. and Weiss, Art and Lanier, Lewis L. and de Jong, Pieter J. and Bluestone, Jeffrey A. and Srivastava, Deepak and McManus, Michael T.. (2012) A resource for the conditional ablation of microRNAs in the mouse. Cell Reports , 1 (4). pp. 385-391.

2011

Lei, Y. and Ripen, A. M. and Ishimaru, N. and Ohigashi, I. and Nagasawa, T. and Jeker, L. T. and Bosl, M. R. and Hollander, G. A. and Hayashi, Y. and Malefyt Rde, W. and Nitta, T. and Takahama, Y.. (2011) Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. Journal of experimental medicine, Vol. 208, H. 2. pp. 383-394.

2010

Jeker, Lukas T. and Bluestone, Jeffrey A.. (2010) Small RNA regulators of T cell-mediated autoimmunity. Journal of Clinical Immunology, 30 (3). pp. 347-357.

2009

Zhou, Xuyu and Bailey-Bucktrout, Samantha and Jeker, Lukas T. and Bluestone, Jeffrey A.. (2009) Plasticity of CD4(+) FoxP3(+) T cells. Current Opinion in Immunology, 21 (3). pp. 281-285.

Zhou, Xuyu and Bailey-Bucktrout, Samantha L. and Jeker, Lukas T. and Penaranda, Cristina and Martínez-Llordella, Marc and Ashby, Meredith and Nakayama, Maki and Rosenthal, Wendy and Bluestone, Jeffrey A.. (2009) Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nature Immunology, 10 (9). pp. 1000-1007.

2008

Hauri-Hohl, Mathias Martin and Zuklys, Saulius and Keller, Marcel P. and Jeker, Lukas T. and Barthlott, Thomas and Moon, Anne M. and Roes, Jürgen and Holländer, Georg A.. (2008) TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution. Blood, 112 (3). pp. 626-634.

Jeker, Lukas Thabo and Barthlott, Thomas and Keller, Marcel P. and Zuklys, Saulius and Hauri-Hohl, Mathias Martin and Deng, Chu-Xia and Holländer, Georg A.. (2008) Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells. Blood, 112 (9). pp. 3688-3695.

Zhou, Xuyu and Jeker, Lukas T. and Fife, Brian T. and Zhu, Shirley and Anderson, Mark S. and McManus, Michael T. and Bluestone, Jeffrey A.. (2008) Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. Journal of Experimental Medicine, 205 (9). pp. 1983-1991.