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Items where Author is "Heim, M. H."

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Number of items: 38.

2018

Ng, C. K. Y. and Di Costanzo, G. G. and Tosti, N. and Paradiso, V. and Coto-Llerena, M. and Roscigno, G. and Perrina, V. and Quintavalle, C. and Boldanova, T. and Wieland, S. and Marino-Marsilia, G. and Lanzafame, M. and Quagliata, L. and Condorelli, G. and Matter, M. S. and Tortora, R. and Heim, M. H. and Terracciano, L. M. and Piscuoglio, S.. (2018) Genetic profiling using plasma-derived cell-free DNA in therapy-naïve hepatocellular carcinoma patients: a pilot study. Annals of Oncology, 29 (5). pp. 1286-1291.

2017

Meier, M.-A. and Suslov, A. and Ketterer, S. and Heim, M. H. and Wieland, S. F.. (2017) Hepatitis B virus covalently closed circular DNA homeostasis is independent of the lymphotoxin pathway during chronic HBV infection. Journal of Viral Hepatitis, 24 (8). pp. 662-671.

2016

Heim, M. H. and Bochud, P. Y. and George, J.. (2016) Host - hepatitis C viral interactions: The role of genetics. J Hepatol, 65 (1 Suppl). pp. 22-32.

Mobin, M. B. and Gerstberger, S. and Teupser, D. and Campana, B. and Charisse, K. and Heim, M. H. and Manoharan, M. and Tuschl, T. and Stoffel, M.. (2016) The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation. Nat Commun, 7. p. 12848.

2015

Rüeger, S. and Bochud, P.-Y. and Dufour, J.-F. and Müllhaupt, B. and Semela, D. and Heim, M. H. and Moradpour, D. and Cerny, A. and Malinverni, R. and Booth, D. R. and Suppiah, V. and George, J. and Argiro, L. and Halfon, P. and Bourlière, M. and Talal, A. H. and Jacobson, I. M. and Patin, E. and Nalpas, B. and Poynard, T. and Pol, S. and Abel, L. and Kutalik, Z. and Negro, F.. (2015) Impact of common risk factors of fibrosis progression in chronic hepatitis C. Gut, 64 (10). pp. 1605-1615.

2014

Rothweiler, S. and Terracciano, L. and Tornillo, L. and Dill, M. T. and Heim, M. H. and Semela, D.. (2014) Downregulation of the Endothelial Genes Notch1 and EphrinB2 in Patients with Nodular Regenerative Hyperplasia. Liver international, Vol. 34, H. 4. pp. 594-603.

Rothweiler, S. and Heim, M. H. and Semela, D.. (2014) Nodular regenerative hyperplasia in a patient with generalized essential telangiectasia : endotheliopathy as causal factor. Hepatology, Vol. 59, No. 6. pp. 2419-2421.

Duong, F. H. and Dill, M. T. and Matter, M. S. and Makowska, Z. and Calabrese, D. and Dietsche, T. and Ketterer, S. and Terracciano, L. and Heim, M. H.. (2014) Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53. Carcinogenesis, Vol. 35, H. 1. pp. 114-122.

Morikawa, K. and Gouttenoire, J. and Hernandez, C. and Thi, V. L. and Tran, H. T. and Lange, C. M. and Dill, M. T. and Heim, M. H. and Donze, O. and Penin, F. and Quadroni, M. and Moradpour, D.. (2014) Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. Hepatology, Vol. 59, No. 2. pp. 423-433.

Quagliata, L. and Matter, M. S. and Piscuoglio, S. and Arabi, L. and Ruiz, C. and Procino, A. and Kovac, M. and Moretti, F. and Makowska, Z. and Boldanova, T. and Andersen, J. B. and Hammerle, M. and Tornillo, L. and Heim, M. H. and Diederichs, S. and Cillo, C. and Terracciano, L. M.. (2014) lncRNA HOTTIP / HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients. Hepatology, Vol. 59, No. 3. pp. 911-923.

2013

Heim, M. H.. (2013) 25 years of interferon-based treatment of chronic hepatitis C : an epoch coming to an end. Nature reviews. Immunology, Vol. 13, H. 7. pp. 535-542.

Lange, C. M. and Bibert, S. and Dufour, J. F. and Cellerai, C. and Cerny, A. and Heim, M. H. and Kaiser, L. and Malinverni, R. and Mullhaupt, B. and Negro, F. and Semela, D. and Moradpour, D. and Kutalik, Z. and Bochud, P. Y.. (2013) Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma. Journal of hepatology, Vol. 59, H. 3. pp. 504-509.

Dill, M. T. and Tornillo, L. and Fritzius, T. and Terracciano, L. and Semela, D. and Bettler, B. and Heim, M. H. and Tchorz, J. S.. (2013) Constitutive Notch2 signaling induces hepatic tumors in mice. Hepatology, Vol. 57, No. 4. pp. 1607-1619.

Lupberger, J. and Duong, F. H. and Fofana, I. and Zona, L. and Xiao, F. and Thumann, C. and Durand, S. C. and Pessaux, P. and Zeisel, M. B. and Heim, M. H. and Baumert, T. F.. (2013) Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha. Hepatology, Vol. 58, No. 4. pp. 1225-1235.

Lange, C. M. and Miki, D. and Ochi, H. and Nischalke, H. D. and Bojunga, J. and Bibert, S. and Morikawa, K. and Gouttenoire, J. and Cerny, A. and Dufour, J. F. and Gorgievski-Hrisoho, M. and Heim, M. H. and Malinverni, R. and Mullhaupt, B. and Negro, F. and Semela, D. and Kutalik, Z. and Muller, T. and Spengler, U. and Berg, T. and Chayama, K. and Moradpour, D. and Bochud, P. Y.. (2013) Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development. PLoS ONE, Vol. 8, H. 5 , e64053.

Zona, L. and Lupberger, J. and Sidahmed-Adrar, N. and Thumann, C. and Harris, H. J. and Barnes, A. and Florentin, J. and Tawar, R. G. and Xiao, F. and Turek, M. and Durand, S. C. and Duong, F. H. and Heim, M. H. and Cosset, F. L. and Hirsch, I. and Samuel, D. and Brino, L. and Zeisel, M. B. and Le Naour, F. and McKeating, J. A. and Baumert, T. F.. (2013) HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex. Cell host & microbe, Vol. 13, H. 3. pp. 302-313.

Heim, M. H.. (2013) Innate immunity and HCV. Journal of hepatology, Vol. 58, H. 3. pp. 564-574.

Makowska, Z. and Blumer, T. and Duong, F. H. and La Monica, N. and Kandimalla, E. R. and Heim, M. H.. (2013) Sequential induction of type I and II interferons mediates a long-lasting gene induction in the liver in response to a novel toll-like receptor 9 agonist. Journal of hepatology, Vol. 58, H. 4. pp. 743-749.

2012

Lange, C. M. and Bibert, S. and Kutalik, Z. and Burgisser, P. and Cerny, A. and Dufour, J. F. and Geier, A. and Gerlach, T. J. and Heim, M. H. and Malinverni, R. and Negro, F. and Regenass, S. and Badenhoop, K. and Bojunga, J. and Sarrazin, C. and Zeuzem, S. and Muller, T. and Berg, T. and Bochud, P. Y. and Moradpour, D.. (2012) A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C. PLoS ONE, Vol. 7, H. 7 , e40159.

Kuske, L. and Mensen, A. and Mullhaupt, B. and Negro, F. and Semela, D. and Moradpour, D. and Male, P. J. and Heim, M. H. and Malinverni, R. and Cerny, A. and Dufour, J. F.. (2012) Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma. Swiss medical weekly, Vol. 142 , w13651.

Dill, M. T. and Rothweiler, S. and Djonov, V. and Hlushchuk, R. and Tornillo, L. and Terracciano, L. and Meili-Butz, S. and Radtke, F. and Heim, M. H. and Semela, D.. (2012) Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice. Gastroenterology, Vol. 142, H. 4 , S. 967-977.e2.

Patin, E. and Kutalik, Z. and Guergnon, J. and Bibert, S. and Nalpas, B. and Jouanguy, E. and Munteanu, M. and Bousquet, L. and Argiro, L. and Halfon, P. and Boland, A. and Mullhaupt, B. and Semela, D. and Dufour, J. F. and Heim, M. H. and Moradpour, D. and Cerny, A. and Malinverni, R. and Hirsch, H. and Martinetti, G. and Suppiah, V. and Stewart, G. and Booth, D. R. and George, J. and Casanova, J. L. and Brechot, C. and Rice, C. M. and Talal, A. H. and Jacobson, I. M. and Bourliere, M. and Theodorou, I. and Poynard, T. and Negro, F. and Pol, S. and Bochud, P. Y. and Abel, L.. (2012) Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology, Vol. 143, H. 5 , S. 1244-1252.e12.

Friedbichler, K. and Themanns, M. and Mueller, K. M. and Schlederer, M. and Kornfeld, J. W. and Terracciano, L. M. and Kozlov, A. V. and Haindl, S. and Kenner, L. and Kolbe, T. and Mueller, M. and Snibson, K. J. and Heim, M. H. and Moriggl, R.. (2012) Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer. Hepatology, Vol. 55, H. 3. pp. 941-952.

Garaigorta, U. and Heim, M. H. and Boyd, B. and Wieland, S. and Chisari, F. V.. (2012) Hepatitis C virus (HCV) induces formation of stress granules whose proteins regulate HCV RNA replication and virus assembly and egress. Journal of virology, Vol. 86, H. 20. pp. 11043-11056.

Bochud, P. Y. and Bibert, S. and Kutalik, Z. and Patin, E. and Guergnon, J. and Nalpas, B. and Goossens, N. and Kuske, L. and Mullhaupt, B. and Gerlach, T. and Heim, M. H. and Moradpour, D. and Cerny, A. and Malinverni, R. and Regenass, S. and Dollenmaier, G. and Hirsch, H. and Martinetti, G. and Gorgiewski, M. and Bourliere, M. and Poynard, T. and Theodorou, I. and Abel, L. and Pol, S. and Dufour, J. F. and Negro, F.. (2012) IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes. Hepatology, Vol. 55, H. 2. pp. 384-394.

Makowska, Z. and Heim, M. H.. (2012) Interferon signaling in the liver during hepatitis C virus infection. Cytokine, Vol. 59, H. 3. pp. 460-466.

Dill, M. T. and Makowska, Z. and Duong, F. H. and Merkofer, F. and Filipowicz, M. and Baumert, T. F. and Tornillo, L. and Terracciano, L. and Heim, M. H.. (2012) Interferon-gamma-stimulated genes, but not USP18, are expressed in livers of patients with acute hepatitis C. Gastroenterology, Vol. 143, H. 3 , S. 777-786.e6.

Heim, M. H.. (2012) Interferons and hepatitis C virus. Swiss medical weekly, Vol. 142 , w13586.

Larrey, D. and Lohse, A. W. and de Ledinghen, V. and Trepo, C. and Gerlach, T. and Zarski, J. P. and Tran, A. and Mathurin, P. and Thimme, R. and Arasteh, K. and Trautwein, C. and Cerny, A. and Dikopoulos, N. and Schuchmann, M. and Heim, M. H. and Gerken, G. and Stern, J. O. and Wu, K. and Abdallah, N. and Girlich, B. and Scherer, J. and Berger, F. and Marquis, M. and Kukolj, G. and Bocher, W. and Steffgen, J.. (2012) Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin. Journal of hepatology, Vol. 57, H. 1. pp. 39-46.

Lange, C. M. and Kutalik, Z. and Morikawa, K. and Bibert, S. and Cerny, A. and Dollenmaier, G. and Dufour, J. F. and Gerlach, T. J. and Heim, M. H. and Malinverni, R. and Mullhaupt, B. and Negro, F. and Moradpour, D. and Bochud, P. Y.. (2012) Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy. Hepatology, Vol. 55, H. 4. pp. 1038-1047.

2011

Makowska, Z. and Duong, F. H. and Trincucci, G. and Tough, D. F. and Heim, M. H.. (2011) Interferon-β and interferon-λ signaling is not affected by interferon-induced refractoriness to interferon-α in vivo. Hepatology, Vol. 53, No. 4. pp. 1154-1163.

2010

Sgier, C. and Müllhaupt, B. and Gerlach, T. and Moradpour, D. and Negro, F. and Malé, P. J. and Heim, M. H. and Malinverni, R. and Cerny, A. and Dufour, J.-F.. (2010) Effect of antiviral therapy on circulating cytokeratin-18 fragments in patients with chronic hepatitis C. Journal of viral hepatitis, Vol. 17, H. 12. pp. 845-850.

Dill, M. T. and Duong, F. H. and Vogt, J. E. and Bibert, S. and Bochud, P. Y. and Terracciano, L. and Papassotiropoulos, A. and Roth, V. and Heim, M. H.. (2010) Interferon-Induced Gene Expression Is a Stronger Predictor of Treatment Response than IL28B Genotype in Patients with Hepatitis C. Gastroenterology, Vol. 140, H. 3 , S. 1021–1031.

2009

Sarasin-Filipowicz, M. and Krol, J. and Markiewicz, I. and Heim, M. H. and Filipowicz, W.. (2009) Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nature medicine, Vol. 15. pp. 31-33.

2008

Khanlari, B. and Bodmer, M. and Terracciano, L. and Heim, M. H. and Fluckiger, U. and Weisser, M.. (2008) Hepatitis with fibrin-ring granulomas. Infection, 36 (4). pp. 381-383.

Sarasin-Filipowicz, M. and Oakeley, E. J. and Duong, F. H. and Christen, V. and Terracciano, L. and Filipowicz, W. and Heim, M. H.. (2008) Interferon signaling and treatment outcome in chronic hepatitis C. Proceedings of the National Academy of Sciences of the United States of America, Vol. 105. pp. 7034-7039.

Ciuffreda, D. and Comte, D. and Cavassini, M. and Giostra, E. and Bühler, L. and Perruchoud, M. and Heim, M. H. and Battegay, M. and Genné, D. and Mulhaupt, B. and Malinverni, R. and Oneta, C. and Bernasconi, E. and Monnat, M. and Cerny, A. and Chuard, C. and Borovicka, J. and Mentha, G. and Pascual, M. and Gonvers, J. J. and Pantaleo, G. and Dutoit, V.. (2008) Polyfunctional HCV-specific T-cell responses are associated with effective control of HCV replication. European Journal of Immunology, Vol. 38, H. 10. pp. 2665-2677.

Bernsmeier, C. and Duong, F. H. and Christen, V. and Pugnale, P. and Negro, F. and Terracciano, L. and Heim, M. H.. (2008) Virus-induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C. Journal of hepatology, Vol. 49, H. 3. pp. 429-440.

This list was generated on Sun Nov 29 13:03:51 2020 CET.