Items where Author is "Hardt, Wolf-Dietrich"

20 July 2022

Lentsch, Verena and Woller, Aurore and Moresi, Claudia and Fattinger, Stefan A. and Aslani, Selma and Hardt, Wolf-Dietrich and Loverdo, Claude and Diard, Médéric and Slack, Emma. (2022) Combined oral vaccination with niche competition can generate sterilizing immunity against entero-pathogenic bacteria.

2022

Bakkeren, Erik and Gül, Ersin and Huisman, Jana S. and Steiger, Yves and Rocker, Andrea and Hardt, Wolf-Dietrich and Diard, Médéric. (2022) Impact of horizontal gene transfer on emergence and stability of cooperative virulence in Salmonella Typhimurium. Nature Communications, 13 (1). p. 1939.

Ramirez Garcia, Alejandro and Hurley, Katherine and Marastoni, Giovanni and Diard, Médéric and Hofer, Sophie and Greppi, Anna and Hardt, Wolf-Dietrich and Lacroix, Christophe and Sturla, Shana J. and Schwab, Clarissa. (2022) Pathogenic and Commensal Gut Bacteria Harboring Glycerol/Diol Dehydratase Metabolize Glycerol and Produce DNA-Reactive Acrolein. Chemical research in toxicology, 35 (10). pp. 1840-1850.

12 February 2021

Bakkeren, Erik and Gül, Ersin and Huisman, Jana S. and Steiger, Yves and Rocker, Andrea and Hardt, Wolf-Dietrich and Diard, Médéric. (2021) Cooperative virulence can emerge via horizontal gene transfer but is stabilized by transmission.

2021

Diard, Médéric and Bakkeren, Erik and Lentsch, Verena and Rocker, Andrea and Bekele, Nahimi Amare and Hoces, Daniel and Aslani, Selma and Arnoldini, Markus and Böhi, Flurina and Schumann-Moor, Kathrin and Adamcik, Jozef and Piccoli, Luca and Lanzavecchia, Antonio and Stadtmueller, Beth M. and Donohue, Nicholas and van der Woude, Marjan W. and Hockenberry, Alyson and Viollier, Patrick H. and Falquet, Laurent and Wüthrich, Daniel and Bonfiglio, Ferdinando and Loverdo, Claude and Egli, Adrian and Zandomeneghi, Giorgia and Mezzenga, Raffaele and Holst, Otto and Meier, Beat H. and Hardt, Wolf-Dietrich and Slack, Emma. (2021) A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants. Nature Microbiology, 6 (7). pp. 830-841.

Bakkeren, Erik and Herter, Joana Anuschka and Huisman, Jana Sanne and Steiger, Yves and Gül, Ersin and Newson, Joshua Patrick Mark and Brachmann, Alexander Oliver and Piel, Jörn and Regoes, Roland and Bonhoeffer, Sebastian and Diard, Médéric and Hardt, Wolf-Dietrich. (2021) Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut. eLife, 10. e69744.

Benz, Fabienne and Huisman, Jana S. and Bakkeren, Erik and Herter, Joana A. and Stadler, Tanja and Ackermann, Martin and Diard, Médéric and Egli, Adrian and Hall, Alex R. and Hardt, Wolf-Dietrich and Bonhoeffer, Sebastian. (2021) Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo. The ISME journal, 15 (3). pp. 862-878.

2020

Bakkeren, Erik and Diard, Médéric and Hardt, Wolf-Dietrich. (2020) Evolutionary causes and consequences of bacterial antibiotic persistence. Nature reviews. Microbiology, 18 (9). pp. 479-490.

Hausmann, Annika and Böck, Desirée and Geiser, Petra and Berthold, Dorothée L. and Fattinger, Stefan A. and Furter, Markus and Bouman, Judith A. and Barthel-Scherrer, Manja and Lang, Crispin M. and Bakkeren, Erik and Kolinko, Isabel and Diard, Médéric and Bumann, Dirk and Slack, Emma and Regoes, Roland R. and Pilhofer, Martin and Sellin, Mikael E. and Hardt, Wolf-Dietrich. (2020) Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression. Mucosal Immunology (13). pp. 530-544.

31 October 2019

Diard, Médéric and Bakkeren, Erik and Hoces, Daniel and Lentsch, Verena and Arnoldini, Markus and Böhi, Flurina and Schumann-Moor, Kathrin and Adamcik, Jozef and Piccoli, Luca and Lanzavecchia, Antonio and Stadtmueller, Beth M. and Donohue, Nicholas and van der Woude, Marjan W. and Hockenberry, Alyson and Viollier, Patrick H. and Falquet, Laurent and Wüthrich, Daniel and Bonfiglio, Ferdinando and Egli, Adrian and Zandomeneghi, Giorgia and Mezzenga, Raffaele and Holst, Otto and Meier, Beat H. and Hardt, Wolf-Dietrich and Slack, Emma. (2019) Rationally designed oral vaccines can set an evolutionary trap for Salmonella Typhimurium.

2019

Balaban, Nathalie Q. and Helaine, Sophie and Lewis, Kim and Ackermann, Martin and Aldridge, Bree and Andersson, Dan I. and Brynildsen, Mark P. and Bumann, Dirk and Camilli, Andrew and Collins, James J. and Dehio, Christoph and Fortune, Sarah M. and Ghigo, Jean-Marc and Hardt, Wolf-Dietrich and Harms, Alexander and Heinemann, Matthias and Hung, Deborah T. and Jenal, Urs and Levin, Bruce R. and Michiels, Jan and Storz, Gisela and Tan, Man-Wah and Tenson, Tanel and Van Melderen, Laurence and Zinkernagel, Annelies. (2019) Definitions and guidelines for research on antibiotic persistence. Nature Reviews Microbiology, 17 (7). pp. 441-448.

Bansept, Florence and Schumann-Moor, Kathrin and Diard, Médéric and Hardt, Wolf-Dietrich and Slack, Emma and Loverdo, Claude. (2019) Enchained growth and cluster dislocation: A possible mechanism for microbiota homeostasis. PLoS computational biology, 15 (5). e1006986.

Wotzka, Sandra Y. and Kreuzer, Markus and Maier, Lisa and Arnoldini, Markus and Nguyen, Bidong D. and Brachmann, Alexander O. and Berthold, Dorothée L. and Zünd, Mirjam and Hausmann, Annika and Bakkeren, Erik and Hoces, Daniel and Gül, Ersin and Beutler, Markus and Dolowschiak, Tamas and Zimmermann, Michael and Fuhrer, Tobias and Moor, Kathrin and Sauer, Uwe and Typas, Athanasios and Piel, Jörn and Diard, Médéric and Macpherson, Andrew J. and Stecher, Bärbel and Sunagawa, Shinichi and Slack, Emma and Hardt, Wolf-Dietrich. (2019) Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice. Nature microbiology, 4 (12). pp. 2164-2174.

Liu, Yansheng and Mi, Yang and Mueller, Torsten and Kreibich, Saskia and Williams, Evan G. and Van Drogen, Audry and Borel, Christelle and Frank, Max and Germain, Pierre-Luc and Bludau, Isabell and Mehnert, Martin and Seifert, Michael and Emmenlauer, Mario and Sorg, Isabel and Bezrukov, Fedor and Sloan Bena, Frederique and Zhou, Hu and Dehio, Christoph and Testa, Giuseppe and Saez-Rodriguez, Julio and Antonarakis, Stylianos E. and Hardt, Wolf-Dietrich and Aebersold, Ruedi. (2019) Multi-omic measurements of heterogeneity in HeLa cells across laboratories. Nature Biotechnology, 37 (3). pp. 314-322.

Bakkeren, Erik and Huisman, Jana S. and Fattinger, Stefan A. and Hausmann, Annika and Furter, Markus and Egli, Adrian and Slack, Emma and Sellin, Mikael E. and Bonhoeffer, Sebastian and Regoes, Roland R. and Diard, Médéric and Hardt, Wolf-Dietrich. (2019) Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut. Nature, 573 (7773). pp. 276-280.

2018

Daga, Neha and Eicher, Simone and Kannan, Abhilash and Casanova, Alain and Low, Shyan H. and Kreibich, Saskia and Andritschke, Daniel and Emmenlauer, Mario and Jenkins, Jeremy L. and Hardt, Wolf-Dietrich and Greber, Urs F. and Dehio, Christoph and von Mering, Christian. (2018) Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition. Nucleic acids research, 46 (18). pp. 9309-9320.

2017

Diard, Médéric and Hardt, Wolf-Dietrich. (2017) Basic Processes in Salmonella-Host Interactions: Within-Host Evolution and the Transmission of the Virulent Genotype. Microbiology Spectrum, 5 (5). epub.

Diard, Médéric and Hardt, Wolf-Dietrich. (2017) Evolution of bacterial virulence. FEMS Microbiology Reviews, 41 (5). pp. 679-697.

Moor, Kathrin and Diard, Médéric and Sellin, Mikael E. and Felmy, Boas and Wotzka, Sandra Y. and Toska, Albulena and Bakkeren, Erik and Arnoldini, Markus and Bansept, Florence and Co, Alma Dal and Völler, Tom and Minola, Andrea and Fernandez-Rodriguez, Blanca and Agatic, Gloria and Barbieri, Sonia and Piccoli, Luca and Casiraghi, Costanza and Corti, Davide and Lanzavecchia, Antonio and Regoes, Roland R. and Loverdo, Claude and Stocker, Roman and Brumley, Douglas R. and Hardt, Wolf-Dietrich and Slack, Emma. (2017) High-avidity IgA protects the intestine by enchaining growing bacteria. Nature, 544 (7651). pp. 498-502.

Diard, Médéric and Bakkeren, Erik and Cornuault, Jeffrey K. and Moor, Kathrin and Hausmann, Annika and Sellin, Mikael E. and Loverdo, Claude and Aertsen, Abram and Ackermann, Martin and De Paepe, Marianne and Slack, Emma and Hardt, Wolf-Dietrich. (2017) Inflammation boosts bacteriophage transfer between Salmonella spp. Science, 355 (6330). pp. 1211-1215.

Schürmann, Nura and Forrer, Pascal and Casse, Olivier and Li, Jiagui and Felmy, Boas and Burgener, Anne-Valérie and Ehrenfeuchter, Nikolaus and Hardt, Wolf-Dietrich and Recher, Mike and Hess, Christoph and Tschan-Plessl, Astrid and Khanna, Nina and Bumann, Dirk. (2017) Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage. Nature Microbiology, 2. p. 16268.

2016

Andritschke, Daniel and Dilling, Sabrina and Emmenlauer, Mario and Welz, Tobias and Schmich, Fabian and Misselwitz, Benjamin and Rämö, Pauli and Rottner, Klemens and Kerkhoff, Eugen and Wada, Teiji and Penninger, Josef M. and Beerenwinkel, Niko and Horvath, Peter and Dehio, Christoph and Hardt, Wolf-Dietrich. (2016) A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. PLoS ONE, 11 (9). e0161965.

Curkić, Ismeta and Schütz, Monika and Oberhettinger, Philipp and Diard, Médéric and Claassen, Manfred and Linke, Dirk and Hardt, Wolf-Dietrich. (2016) Epitope-Tagged Autotransporters as Single-Cell Reporters for Gene Expression by a Salmonella Typhimurium wbaP Mutant. PloS one, 11 (5). e0154828.

Colgan, Aoife M. and Kröger, Carsten and Diard, Médéric and Hardt, Wolf-Dietrich and Puente, José L. and Sivasankaran, Sathesh K. and Hokamp, Karsten and Hinton, Jay C. D.. (2016) The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium. PLoS genetics, 12 (8). e1006258.

11 November 2015

Kreibich, Saskia and Emmenlauer, Mario and Fredlund, Jennifer and Rämö, Pauli and Münz, Christian and Dehio, Christoph and Enninga, Jost and Hardt, Wolf-Dietrich. (2015) Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1. Cell host & microbe, 18 (5). pp. 527-537.

21 October 2015

Schmich, Fabian and Szczurek, Ewa and Kreibich, Saskia and Dilling, Sabrina and Andritschke, Daniel and Casanova, Alain and Low, Shyan Huey and Eicher, Simone and Muntwiler, Simone and Emmenlauer, Mario and Rämo, Pauli and Conde-Alvarez, Raquel and von Mering, Christian and Hardt, Wolf-Dietrich and Dehio, Christoph and Beerenwinkel, Niko. (2015) Erratum to: gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology, 16 (233). p. 1.

7 October 2015

Schmich, Fabian and Szczurek, Ewa and Kreibich, Saskia and Dilling, Sabrina and Andritschke, Daniel and Casanova, Alain and Low, Shyan Huey and Eicher, Simone and Muntwiler, Simone and Emmenlauer, Mario and Rämö, Pauli and Conde-Alvarez, Raquel and von Mering, Christian and Hardt, Wolf-Dietrich and Dehio, Christoph and Beerenwinkel, Niko. (2015) gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology, 16 (220). pp. 1-12.

2015

Maier, Lisa and Diard, Médéric and Sellin, Mikael E. and Chouffane, Elsa-Sarah and Trautwein-Weidner, Kerstin and Periaswamy, Balamurugan and Slack, Emma and Dolowschiak, Tamas and Stecher, Bärbel and Loverdo, Claude and Regoes, Roland R. and Hardt, Wolf-Dietrich. (2015) Correction: Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis. PLoS Pathogens, 11 (7). e1005047.

December 2014

Rämö, Pauli and Drewek, Anna and Arrieumerlou, Cécile and Beerenwinkel, Niko and Ben-Tekaya, Houchaïma and Cardel, Bettina and Casanova, Alain and Conde-Alvarez, Raquel and Cossart, Pascale and Csúcs, Gábor and Eicher, Simone and Emmenlauer, Mario and Greber, Urs and Hardt, Wolf-Dietrich and Helenius, Ari and Kasper, Christoph and Kaufmann, Andreas and Kreibich, Saskia and Kühbacher, Andreas and Kunszt, Peter and Low, Shyan Huey and Mercer, Jason and Mudrak, Daria and Muntwiler, Simone and Pelkmans, Lucas and Pizarro-Cerdá, Javier and Podvinec, Michael and Pujadas, Eva and Rinn, Bernd and Rouilly, Vincent and Schmich, Fabian and Siebourg-Polster, Juliane and Snijder, Berend and Stebler, Michael and Studer, Gabriel and Szczurek, Ewa and Truttmann, Matthias and von Mering, Christian and Vonderheit, Andreas and Yakimovich, Artur and Bühlmann, Peter and Dehio, Christoph. (2014) Simultaneous analysis of large-scale RNAi screens for pathogen entry. BMC Genomics, 15 (1). p. 1162.

2014

Diard, Médéric and Sellin, Mikael E. and Dolowschiak, Tamas and Arnoldini, Markus and Ackermann, Martin and Hardt, Wolf-Dietrich. (2014) Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium. Current Biology, 24 (17). pp. 2000-2005.

Arnoldini, Markus and Vizcarra, Ima Avalos and Peña-Miller, Rafael and Stocker, Nicolas and Diard, Médéric and Vogel, Viola and Beardmore, Robert E. and Hardt, Wolf-Dietrich and Ackermann, Martin. (2014) Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation. PLoS Biology, 12 (8). e1001928.

Sellin, Mikael E. and Müller, Anna A. and Felmy, Boas and Dolowschiak, Tamas and Diard, Médéric and Tardivel, Aubry and Maslowski, Kendle M. and Hardt, Wolf-Dietrich. (2014) Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa. Cell Host & Microbe, 16 (2). pp. 237-248.

Maier, Lisa and Diard, Médéric and Sellin, Mikael E. and Chouffane, Elsa-Sarah and Trautwein-Weidner, Kerstin and Periaswamy, Balamurugan and Slack, Emma and Dolowschiak, Tamas and Stecher, Bärbel and Loverdo, Claude and Regoes, Roland R. and Hardt, Wolf-Dietrich. (2014) Granulocytes impose a tight bottleneck upon the gut luminal pathogen population during Salmonella typhimurium colitis. PLoS Pathogens, 10 (12). e1004557.

Franceschini, Andrea and Meier, Roger and Casanova, Alain and Kreibich, Saskia and Daga, Neha and Andritschke, Daniel and Dilling, Sabrina and Rämö, Pauli and Emmenlauer, Mario and Kaufmann, Andreas and Conde-Álvarez, Raquel and Low, Shyan Huey and Pelkmans, Lucas and Helenius, Ari and Hardt, Wolf-Dietrich and Dehio, Christoph and von Mering, Christian. (2014) Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proceedings of the National Academy of Sciences, 111 (12). pp. 4548-4553.

2013

Diard, Médéric and Garcia, Victor and Maier, Lisa and Remus-Emsermann, Mitja N. P. and Regoes, Roland R. and Ackermann, Martin and Hardt, Wolf-Dietrich. (2013) Stabilization of cooperative virulence by the expression of an avirulent phenotype. Nature, 494 (7437). pp. 353-356.

2012

Kaiser, Patrick and Diard, Médéric and Stecher, Bärbel and Hardt, Wolf-Dietrich. (2012) The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune response. Immunological Reviews, 245 (1). pp. 56-83.

2011

Truttmann, Matthias C. and Misselwitz, Benjamin and Huser, Sonja and Hardt, Wolf-Dietrich and Critchley, David R. and Dehio, Christoph. (2011) Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake. Journal of Cell Science, 124 (21). pp. 3591-3602.

2004

Springer, Burkhard and Sander, Peter and Sedlacek, Ludwig and Hardt, Wolf-Dietrich and Mizrahi, Valerie and Schär, Primo and Böttger, Erik C.. (2004) Lack of mismatch correction facilitates genome evolution in mycobacteria. Molecular Microbiology, Vol. 53, H. 6. pp. 1601-1609.