Items where Author is "Christofori, G."

2016

Diepenbruck, M. and Christofori, G.. (2016) Epithelial–mesenchymal transition (EMT) and metastasis: yes, no, maybe? Current Opinion in Cell Biolog, 43. pp. 7-13.

2014

Braeutigam, C. and Rago, L. and Rolke, A. and Waldmeier, L. and Christofori, G. and Winter, J.. (2014) The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion. Oncogene, Vol. 33, H. 9. pp. 1082-1092.

2013

Fagiani, E. and Christofori, G.. (2013) Angiopoietins in angiogenesis. Cancer letters, Vol. 328, H. 1. pp. 18-26.

Tiwari, N. and Meyer-Schaller, N. and Arnold, P. and Antoniadis, H. and Pachkov, M. and van Nimwegen, E. and Christofori, G.. (2013) Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8). PLoS ONE, Vol. 8, H. 2 , e57329.

Saxena, M. and Christofori, G.. (2013) Rebuilding cancer metastasis in the mouse. Molecular oncology, Vol. 7, H. 2. pp. 283-296.

Tiwari, N. and Tiwari, V. K. and Waldmeier, L. and Balwierz, P. J. and Arnold, P. and Pachkov, M. and Meyer-Schaller, N. and Schubeler, D. and van Nimwegen, E. and Christofori, G.. (2013) Sox4 is a master regulator of epithelial-mesenchymal transition by controlling ezh2 expression and epigenetic reprogramming. Cancer cell, Vol. 23, H. 6. pp. 768-783.

Peier, M. and Walpen, T. and Christofori, G. and Battegay, E. and Humar, R.. (2013) Sprouty2 expression controls endothelial monolayer integrity and quiescence. Angiogenesis, Vol. 16, H. 2. pp. 455-468.

Saupe, F. and Schwenzer, A. and Jia, Y. and Gasser, I. and Spenle, C. and Langlois, B. and Kammerer, M. and Lefebvre, O. and Hlushchuk, R. and Rupp, T. and Marko, M. and van der Heyden, M. and Cremel, G. and Arnold, C. and Klein, A. and Simon-Assmann, P. and Djonov, V. and Neuville-Mechine, A. and Esposito, I. and Slotta-Huspenina, J. and Janssen, K. P. and de Wever, O. and Christofori, G. and Hussenet, T. and Orend, G.. (2013) Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model. Cell reports, Vol. 5, H. 2. pp. 482-492.

Michaloglou, C. and Lehmann, W. and Martin, T. and Delaunay, C. and Hueber, A. and Barys, L. and Niu, H. and Billy, E. and Wartmann, M. and Ito, M. and Wilson, C. J. and Digan, M. E. and Bauer, A. and Voshol, H. and Christofori, G. and Sellers, W. R. and Hofmann, F. and Schmelzle, T.. (2013) The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity. PLoS ONE, Vol. 8, H. 4 , e61916.

Chatterjee, S. and Heukamp, L. C. and Siobal, M. and Schottle, J. and Wieczorek, C. and Peifer, M. and Frasca, D. and Koker, M. and Konig, K. and Meder, L. and Rauh, D. and Buettner, R. and Wolf, J. and Brekken, R. A. and Neumaier, B. and Christofori, G. and Thomas, R. K. and Ullrich, R. T.. (2013) Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. Journal of Clinical Investigation, Vol. 123, H. 4. pp. 1732-1740.

2012

Sleeman, J. P. and Christofori, G. and Fodde, R. and Collard, J. G. and Berx, G. and Decraene, C. and Ruegg, C.. (2012) Concepts of metastasis in flux : the stromal progression model. Seminars in cancer biology, Vol. 22, H. 3. pp. 174-186.

Tiwari, N. and Gheldof, A. and Tatari, M. and Christofori, G.. (2012) EMT as the ultimate survival mechanism of cancer cells. Seminars in cancer biology, Vol. 22, H. 3. pp. 194-207.

Spano, D. and Heck, C. and De Antonellis, P. and Christofori, G. and Zollo, M.. (2012) Molecular networks that regulate cancer metastasis. Seminars in cancer biology, Vol. 22, H. 3. pp. 234-249.

Waldmeier, L. and Meyer-Schaller, N. and Diepenbruck, M. and Christofori, G.. (2012) Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo. PLoS ONE, Vol. 7, H. 11 , e48651.

2011

Fagiani, E. and Lorentz, P. and Kopfstein, L. and Christofori, G.. (2011) Angiopoietin-1 and -2 exert antagonistic functions in tumor angiogenesis, yet both induce lymphangiogenesis. Cancer research, Vol. 71, H. 17. pp. 5717-5727.

Fendrich, V. and Rehm, J. and Waldmann, J. and Buchholz, M. and Christofori, G. and Lauth, M. and Slater, E. P. and Bartsch, D. K.. (2011) Hedgehog inhibition with cyclopamine represses tumor growth and prolongs survival in a transgenic mouse model of islet cell tumors. Annals of surgery, Vol. 253, H. 3. pp. 546-552.

Laurent, J. and Hull, E. F. and Touvrey, C. and Kuonen, F. and Lan, Q. and Lorusso, G. and Doucey, M. A. and Ciarloni, L. and Imaizumi, N. and Alghisi, G. C. and Fagiani, E. and Zaman, K. and Stupp, R. and Shibuya, M. and Delaloye, J. F. and Christofori, G. and Ruegg, C.. (2011) Proangiogenic factor PlGF programs CD11b(+) myelomonocytes in breast cancer during differentiation of their hematopoietic progenitors. Cancer research, Vol. 71,11. pp. 3781-3791.

Yilmaz, M. and Maass, D. and Tiwari, N. and Waldmeier, L. and Schmidt, P. and Lehembre, F. and Christofori, G.. (2011) Transcription factor Dlx2 protects from TGFβ-induced cell-cycle arrest and apoptosis. The EMBO journal, Vol. 30, H. 21. pp. 4489-4499.

2010

Grotegut, S. and Kappler, R. and Tarimoradi, S. and Lehembre, F. and Christofori, G. and Von Schweinitz, D.. (2010) Hepatocyte growth factor protects hepatoblastoma cells from chemotherapy-induced apoptosis by AKT activation. International journal of oncology, Vol. 36, H. 5. pp. 1261-1267.

2009

Zumsteg, A. and Christofori, G.. (2009) Corrupt policemen : inflammatory cells promote tumor angiogenesis. Current opinion in oncology : review articles, recommended reading, bibliography of the world literature, Vol. 21. pp. 60-70.

Schomber, T. and Zumsteg, A. and Strittmatter, K. and Crnic, I. and Antoniadis, H. and Littlewood-Evans, A. and Wood, J. and Christofori, G.. (2009) Differential effects of the vascular endothelial growth factor receptor inhibitor PTK787/ZK222584 on tumor angiogenesis and tumor lymphangiogenesis. Molecular cancer therapeutics, Vol. 8. pp. 55-63.

2008

Sobczak, I. and Galabova-Kovacs, G. and Sadzak, I. and Kren, A. and Christofori, G. and Baccarini, M.. (2008) B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic beta-cell carcinogenesis. Oncogene, Vol. 27. pp. 4779-4787.

Tammela, T. and Zarkada, G. and Wallgard, E. and Murtomäki, A. and Suchting, S. and Wirzenius, M. and Waltari, M. and Hellström, M. and Schomber, T. and Peltonen, R. and Freitas, C. and Duarte, A. and Isoniemi, H. and Laakkonen, P. and Christofori, G. and Ylä-Herttuala, S. and Shibuya, M. and Pytowski, B. and Eichmann, A. and Betsholtz, C. and Alitalo, K.. (2008) Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature, Vol. 454, H. 7204. pp. 656-660.

Jäggi, F. and Cabrita, M. A. and Perl, A. K. and Christofori, G.. (2008) Modulation of endocrine pancreas development but not beta-cell carcinogenesis by Sprouty4. Molecular Cancer Research, Vol. 6. pp. 468-482.

Lehembre, F. and Yilmaz, M. and Wicki, A. and Schomber, T. and Strittmatter, K. and Ziegler, D. and Kren, A. and Went, P. and Derksen, P. W. and Berns, A. and Jonkers, J. and Christofori, G.. (2008) NCAM-induced focal adhesion assembly : a functional switch upon loss of E-cadherin. The EMBO journal, Vol. 27, H. 9. pp. 2603-2615.

Cabrita, M. A. and Christofori, G.. (2008) Sprouty proteins, masterminds of receptor tyrosine kinase signaling. Angiogenesis, Vol. 11, H. 1. pp. 53-62.

1991

Keller, W. and Bienroth, S. and Lang, K. M. and Christofori, G.. (1991) Cleavage and polyadenylation factor CPF specifically interacts with the pre-mRNA 3' processing signal AAUAAA. The EMBO Journal, 10 (13). pp. 4241-4249.

1989

Christofori, G. and Keller, W.. (1989) Poly(A) polymerase purified from HeLa cell nuclear extract is required for both cleavage and polyadenylation of pre-mRNA in vitro. Molecular and Cellular Biology, 9 (1). pp. 193-203.

1988

Christofori, G. and Keller, W.. (1988) 3' cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP. Cell, 54 (6). pp. 875-889.

1987

Humphrey, T. and Christofori, G. and Lucijanic, V. and Keller, W.. (1987) Cleavage and polyadenylation of messenger RNA precursors in vitro occurs within large and specific 3' processing complexes. The EMBO Journal, 6 (13). pp. 4159-4168.

Christofori, G. and Frendewey, D. and Keller, W.. (1987) Two spliceosomes can form simultaneously and independently on synthetic double-intron messenger RNA precursors. The EMBO Journal, 6 (6). pp. 1747-1755.