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Items where contributor is "Gademann, Karl"

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2016

Gomes, José and Daeppen, Christophe and Liffert, Raphael and Roesslein, Joel and Kaufmann, Elias and Heikinheim, Annakasia and Neuburger, Markus and Gademann, Karl. (2016) Formal Total Synthesis of (−)-Jiadifenolide and Synthetic Studies toward seco-Prezizaane-Type Sesquiterpenes. Journal of Organic Chemistry, 81 (22). pp. 11017-11034.

Scherer, Manuel and Bezold, Dominik and Gademann, Karl. (2016) Investigating the Toxicity of the Aeruginosin Chlorosulfopeptides by Chemical Synthesis. Angewandte Chemie International Edition, 55 (32). pp. 9427-9431.

De Sarkar, Suman and Blom, Judith F. and Bethuel, Yann and Jüttner, Friedrich and Gademann, Karl. (2016) Allelopathic Activity of the Iron Chelator Anachelin – A Molecular Hybrid with a Dual Mode of Action. Helvetica Chimica Acta , 99 (10). pp. 760-773.

Lascano, Santiago and Zhang, Kang-Da and Wehlauch, Robin and Gademann, Karl and Sakai, Naomi and Matile, Stefan. (2016) The third orthogonal dynamic covalent bond. Chemical Science, 7. pp. 4720-4724.

Crane, Erika A. and Gademann, Karl. (2016) Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis. Angewandte Chemie International Edition, 55 (12). pp. 3882-3902.

Pinto-Carbò, Marta and Sieber, Simon and Dessein, Steven and Wicker, Thomas and Verstraete, Brecht and Gademann, Karl and Eberl, Leo and Carlier, Aurelien. (2016) Evidence of horizontal gene transfer between obligate leaf nodule symbionts. ISME Journal, 10. pp. 2092-2105.

Faltermann, Susanne and Grundler, Verena and Gademann, Karl and Pernthaler, Jakob and Fent, Karl. (2016) Comparative effects of nodularin and microcystin-LR in zebrafish: 2. Uptake and molecular effects in eleuthero-embryos and adult liver with focus on endoplasmic reticulum stress. AquaticToxicology, 171. pp. 77-87.

2015

Bader, Samuel L. and Luescher, Michael U. and Gademann, Karl. (2015) Synthesis of maculalactone A and derivatives for environmental fate tracking studies. Organic & biomolecular chemistry, Vol. 13, H. 1. S. 199-206.

2014

Portmann, Cyril and Sieber, Simon and Wirthensohn, Silvan and Blom, Judith F. and Da Silva, Laeticia and Baudat, Emilie and Kaiser, Marcel and Brun, Reto and Gademann, Karl. (2014) Balgacyclamides, antiplasmodial heterocyclic peptides from Microcystis aeruguinosa EAWAG 251. Journal of natural products, Vol. 77, H. 3. S. 557-562.

Schmid, Fabian and Bernasconi, Maurizio and Jessen, Henning J. and Pfaltz, Andreas and Gademann, Karl. (2014) Catalytic Enantioselective Total Synthesis of (–)-Pyridovericin. Synthesis, 46 (07). pp. 864-870.

Kohler, Esther and Grundler, Verena and Häussinger, Daniel and Kurmayer, Rainer and Gademann, Karl and Pernthaler, Jakob and Blom, Judith F. . (2014) The toxicity and enzyme activity of a chlorine and sulfate containing aeruginosin isolated from a non-microcystin-producing Planktothrix strain. Harmful Algae, 39. pp. 154-160.

Burch, Patrick and Schmid, Fabian and Gademann, Karl. (2014) Neuritogenic surfaces using natural product analogs. Advanced healthcare materials, Vol. 3, H. 9. S. 1415-1419.

Burch, Patrick and Chicca, Andrea and Gertsch, Jürg and Gademann, Karl. (2014) Functionally Optimized Neuritogenic Farinosone C Analogs : SAR-Study and Investigations on Their Mode of Action. ACS medicinal chemistry letters, Vol. 5, H. 2. S. 172-177.

Grundler, Verena and Gademann, Karl. (2014) Direct arginine modification in native peptides and application to chemical probe development. ACS medicinal chemistry letters, Vol. 5, H. 12. S. 1290-1295.

2013

Gomes, José and Grunau, Alexander and Lawrence, Adrien K. and Eberl, Leo and Gademann, Karl. (2013) Bioinspired, releasable quorum sensing modulators. Chemical Communications, 49 (2). pp. 155-157.

Schmid, Fabian and Jessen, Henning J. and Burch, Patrick and Gademann, Karl. (2013) Truncated militarinone fragments identified by total chemical synthesis induce neurite outgrowth. MedChemComm , 4 (1). pp. 135-139.

Hoecker, Johannes and Gademann, Karl. (2013) Enantioselective Total Syntheses and Absolute Configuration of JBIR-02 and Mer-A2026B. Organic letters, Vol. 15, H. 3 , S. 670–673.

Miyatake-Ondozabal, Hideki and Bannwart, Linda M. and Gademann, Karl. (2013) Enantioselective total synthesis of virosaine A and bubbialidine. Chemical Communications, 49 (19). pp. 1921-1923.

Liffert, Raphael and Hoecker, Johannes and Jana, Chandan K. and Woods, Tom M. and Burch, Patrick and Jessen, Henning J. and Neuburger, Markus and Gademann, Karl. (2013) Withanolide A: synthesis and structural requirements for neurite outgrowth. Chemical science, Vol. 4, H. 7. S. 2851-2857.

Hoecker, Johannes and Liffert, Raphael and Burch, Patrick and Wehlauch, Robin and Gademann, Karl. (2013) Caged retinoids as photoinducible activators : implications for cell differentiation and neurite outgrowth. Organic & biomolecular chemistry, Vol. 11, H. 20. S. 3314.

Gomes, José and Grunau, Alexander and Lawrence, Adrien K. and Eberl, Leo and Gademann, Karl. (2013) Bioinspired surfaces against bacterial infections. Chimia, 67 (4). pp. 275-278.

Thommen, Christophe and Jana, Chandan Kumar and Neuburger, Markus and Gademann, Karl. (2013) Syntheses of Taiwaniaquinone F and Taiwaniaquinol A via an Unusual Remote C-H Functionalization. Organic letters, Vol. 15, H. 6. S. 1390-1393.

Gomes, José and Huber, Natalie and Grunau, Alexander and Eberl, Leo and Gademann, Karl. (2013) Fluorescent Labeling Agents for Quorum-Sensing Receptors (FLAQS) in Live Cells. Chemistry: a European journal, Vol. 19, H. 30. S. 9766-9770.

Makhlouf Brahmi, Malika and Portmann, Cyril and D`Ambrosio, Danilo and Woods, Tom M. and Banfi, Damiano and Reichenbach, Patrick and Da Silva, Laeticia and Baudat, Emilie and Turcatti, Gerardo and Lingner, Joachim and Gademann, Karl. (2013) Telomerase Inhibitors from Cyanobacteria : Isolation and Synthesis of Sulfoquinovosyl Diacylglycerols from Microcystis aeruguinosaPCC 7806. Chemistry: a European journal, Vol. 19, H. 14. S. 4596-4601.

2012

Elamparuthi, Elangovan and Fellay, Cindy and Neuburger, Markus and Gademann, Karl. (2012) Total Synthesis of Cyrneine A. Angewandte Chemie International Edition, 51 (17). pp. 4071-4073.

Cantó, Carles and Houtkooper, Riekelt H. and Pirinen, Eija and Youn, Dou Y. and Oosterveer, Maaike H. and Cen, Yana and Fernandez-Marcos, Pablo J. and Yamamoto, Hiroyasu and Andreux, Pénélope A. and Cettour-Rose, Philippe and Gademann, Karl and Rinsch, Chris and Schoonjans, Kristina and Sauve, Anthony A. and Auwerx, Johan. (2012) The NAD(+) Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity. Cell metabolism, Vol. 15, H. 6. S. 838-847.

Gademann, Karl and Wach, Jean-Yves. (2012) Reduce to the Maximum : Truncated Natural Products as Powerful Modulators of Biological Processes. Synlett, 2012, Vol. 2. S. 163-170.

Wehlauch, Robin and Hoecker, Johannes and Gademann, Karl. (2012) Nitrocatechols as Tractable Surface Release Systems. ChemPlusChem, 77. pp. 1071-1074.

2011

Schumacher, Andreas and Jessen, Henning J. and Shaw, Trawis and Pfaltz, Andreas and Gademann, Karl. (2011) A Unified Approach for the Stereoselective Total Synthesis of Pyridone Alkaloids and Their Neuritogenic Activity. Angewandte Chemie International Edition, 50 (18). pp. 4222-4226.

Schumacher, Andreas and Jessen, Henning J. and Schmid, Fabian and Pfaltz, Andreas and Gademann, Karl. (2011) Catalytic Enantioselective Total Synthesis of (+)-Torrubiellone. Organic Letters, 13 (16). pp. 4368-4370.

Gademann, Karl. (2011) Controlling protein transport by small molecules. Current drug targets, Vol. 12, H. 11. S. 1574-1580.

Gademann, Karl. (2011) Out in the green : biologically active metabolites produced by cyanobacteria. Chimia, 65 (6). pp. 416-419.

Gademann, Karl and Sieber, Simon. (2011) Chemical Interference of Biological Systems with Natural Products. Chimia, 65 (11). pp. 835-838.

Jana, Chandan Kumar and Hoecker, Johannes and Woods, Tom M. and Jessen, Henning J. and Neuburger, Markus and Gademann, Karl. (2011) Synthesis of Withanolide A, Biological Evaluation of Its Neuritogenic Properties, and Studies on Secretase Inhibition. Angewandte Chemie. International edition in English, Vol. 50, H. 36. S. 8407-8411.

2010

Bonazzi, S. and Barbaras, D. and Patiny, L. and Scopelliti, R. and Schneider, P. and Cole, S. T. and Kaiser, M. and Brun, R. and Gademann, K.. (2010) Antimalarial and antitubercular nostocarboline and eudistomin derivatives: Synthesis, in vitro and in vivo biological evaluation. Bioorganic and Medicinal Chemistry, 18 (4). pp. 1464-1476.

Saxer, S. and Pieles, U. and Elsener, M. and Horisberger, M. and Tosatti, S. and Textor, M. and Gademann, K. and Zurcher, S.. (2010) Design of a high-throughput device for screening surface modification protocols. Progress in Organic Coatings, 67 (1). pp. 20-27.

Saxer, S. and Portmann, C. and Tosatti, S. and Gademann, K. and Zurcher, S. and Textor, M.. (2010) Surface Assembly of Catechol-Functionalized Poly(L-lysine)-graft-poly(ethylene glycol) Copolymer on Titanium Exploiting Combined Electrostatically Driven Self-Organization and Blomimetic Strong Adhesion. Macromolecules, Vol. 43, H. 2. S. 1050-1060.

Wach, J. Y. and Guttinger, S. and Kutay, U. and Gademann, K.. (2010) The cytotoxic styryl lactone goniothalamin is an inhibitor of nucleocytoplasmic transport. Bioorganic & medicinal chemistry letters, Vol. 20, H. 9. S. 2843-2846.

Jessen, H. J. and Gademann, K.. (2010) Total Synthesis of the Marine Alkaloid Palau'amine. Angewandte Chemie. International edition in English, Vol. 49, H. 17. S. 2972-2974.

Locher, H. H. and Ritz, D. and Pfaff, P. and Gaertner, M. and Knezevic, A. and Sabato, D. and Schroeder, S. and Barbaras, D. and Gademann, K.. (2010) Dimers of Nostocarboline with Potent Antibacterial Activity. Chemotherapy, 56 (4). pp. 318-324.

Jessen, H. J. and Gademann, K.. (2010) 4-Hydroxy-2-pyridone alkaloids : Structures and synthetic approaches. Natural product reports, Vol. 27, H. 8. S. 1168-1185.

Okello, W. and Portmann, C. and Erhard, M. and Gademann, K. and Kurmayer, R.. (2010) Occurrence of Microcystin-Producing Cyanobacteria in Ugandan Freshwater Habitats. Environmental toxicology, Vol. 25, H. 4. S. 367-380.

Okello, W. and Ostermaier, V. and Portmann, C. and Gademann, K. and Kurmayer, R.. (2010) Spatial isolation favours the divergence in microcystin net production by Microcystis in Ugandan freshwater lakes. Water research, Vol. 44, H. 9. S. 2803-2814.

Jana, C. K. and Scopelliti, R. and Gademann, K.. (2010) Connecting C-19 Norditerpenoids to C-20 Diterpenes : Total Syntheses of 6-Hydroxy-5,6-dehydrosugiol, 6-Hydroxysugiol, and Taiwaniaquinone H, and Formal Synthesis of Dichroanone. Synthesis, H. 13. S. 2223-2232.

Jana, C. K. and Scopelliti, R. and Gademann, K.. (2010) A Synthetic Entry into the Taiwaniaquinoids Based on a Biogenetic Hypothesis : Total Synthesis of (-)-Taiwaniaquinone H. Chemistry - A European Journal, 16 (26). pp. 7692-7695.

Gademann, K. and Portmann, C. and Blom, J. F. and Zeder, M. and Juttner, F.. (2010) Multiple Toxin Production in the Cyanobacterium Microcystis : Isolation of the Toxic Protease Inhibitor Cyanopeptolin 1020. Journal of Natural Products, 73 (5). pp. 980-984.

Bonazzi, S. and Eidam, O. and Guttinger, S. and Wach, J. Y. and Zemp, I. and Kutay, U. and Gademann, K.. (2010) Anguinomycins and Derivatives : Total Syntheses, Modeling, and Biological Evaluation of the Inhibition of Nucleocytoplasmic Transport. Journal of the American Chemical Society, 132 (4). pp. 1432-1442.

Bonazzi, S. and Binaghi, M. and Fellay, C. and Wach, J. Y. and Gademann, K.. (2010) Synthetic Studies on the Sporolides : Exploration of the Enediyne Route. Synthesis, 4. pp. 631-642.

Malisova, B. and Tosatti, S. and Textor, M. and Gademann, K. and Zurcher, S.. (2010) Poly(ethylene glycol) Adlayers Immobilized to Metal Oxide Substrates Through Catechol Derivatives : Influence of Assembly Conditions on Formation and Stability. Langmuir, Vol. 26, H. 6. S. 4018-4026.