Items where Author is "Grzesiek, Stephan"
Number of items: 60. 2023Isaikina, Polina and Petrovic, Ivana and Jakob, Roman P. and Sarma, Parishmita and Ranjan, Ashutosh and Baruah, Minakshi and Panwalkar, Vineet and Maier, Timm and Shukla, Arun K. and Grzesiek, Stephan. (2023) A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes. Molecular cell, 83 (12). pp. 2108-2121.e7. 2022Jahnke, Wolfgang and Paladini, Johannes and Habazettl, Judith M. and Wiget, Andrea and Loo, Alice and Cowan Jacob, Sandra W. and Grzesiek, Stephan and Manley, Paul W.. (2022) Correspondence on "Synergy and Antagonism between Allosteric and Active-Site Inhibitors of Abl Tyrosine Kinase". Angewandte Chemie International Edition, 61 (46). e202117276. Abiko, Layara Akemi and Dias Teixeira, Raphael and Engilberge, Sylvain and Grahl, Anne and Mühlethaler, Tobias and Sharpe, Timothy and Grzesiek, Stephan. (2022) Filling of a water-free void explains the allosteric regulation of the β1-adrenergic receptor by cholesterol. Nature Chemistry, 14 (10). pp. 1133-1141. Grzesiek, Stephan and Paladini, Johannes and Habazettl, Judith and Sonti, Rajesh. (2022) Imatinib disassembles the regulatory core of Abelson kinase by binding to its ATP site and not by binding to its myristoyl pocket. Magnetic Resonance, 3. pp. 91-99. Wu, Feng-Jie and Rieder, Pascal S. and Abiko, Layara Akemi and Rössler, Philip and Gossert, Alvar D. and Häussinger, Daniel and Grzesiek, Stephan. (2022) Nanobody GPS by PCS: An Efficient New NMR Analysis Method for G Protein Coupled Receptors and Other Large Proteins. Journal of the American Chemical Society, 144 (47). pp. 21728-21740. Isaikina, Polina and Tsai, Ching-Ju and Petrovic, Ivana and Rogowski, Marco and Dürr, Alexandra Meng and Grzesiek, Stephan. (2022) Preparation of a stable CCL5·CCR5·Gi signaling complex for Cryo-EM analysis. In: Biomolecular Interactions Part B, 169. Amsterdam, Netherlands, pp. 115-141. 2021Abiko, Layara Akemi and Rogowski, Marco and Gautier, Antoine and Schertler, Gebhard and Grzesiek, Stephan. (2021) Efficient production of a functional G protein-coupled receptor in E. coli for structural studies. Journal of Biomolecular NMR, 75 (1). pp. 25-38. Isaikina, Polina and Tsai, Ching-Ju and Dietz, Nikolaus and Pamula, Filip and Grahl, Anne and Goldie, Kenneth N. and Guixà-González, Ramon and Branco, Camila and Paolini-Bertrand, Marianne and Calo, Nicolas and Cerini, Fabrice and Schertler, Gebhard F. X. and Hartley, Oliver and Stahlberg, Henning and Maier, Timm and Deupi, Xavier and Grzesiek, Stephan. (2021) Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist. Science Advances, 7 (25). eabg8685. 2020Grahl, Anne and Abiko, Layara Akemi and Isogai, Shin and Sharpe, Timothy and Grzesiek, Stephan. (2020) A high-resolution description of β1-adrenergic receptor functional dynamics and allosteric coupling from backbone NMR. Nature communications, 11 (1). p. 2216. Hee, Chee-Seng and Habazettl, Judith and Schmutz, Christoph and Schirmer, Tilman and Jenal, Urs and Grzesiek, Stephan. (2020) Intercepting second-messenger signaling by rationally designed peptides sequestering c-di-GMP. Proceedings of the National Academy of Sciences of the United States of America, 117 (29). pp. 17211-17220. Franke, Bastian and Frigård, Tuomo and Grzesiek, Stephan and Isogai, Shin. (2020) Versatile modules enable automated multi-column purifications on the ÄKTA pure chromatography system. Journal of Chromatography A, 1618. p. 460846. 2019Opitz, Christian and Ahrné, Erik and Goldie, Kenneth N. and Schmidt, Alexander and Grzesiek, Stephan. (2019) Deuterium induces a distinctive Escherichia coli proteome that correlates with the reduction in growth rate. Journal of Biological Chemistry, 294 (7). pp. 2279-2292. Abiko, Layara Akemi and Grahl, Anne and Grzesiek, Stephan. (2019) High Pressure Shifts the β1-Adrenergic Receptor to the Active Conformation in the Absence of G Protein. Journal of the American Chemical Society, 141 (42). pp. 16663-16670. Opitz, Christian and Schade, Grit and Kaufmann, Silvan and Di Berardino, Marco and Ottiger, Marcel and Grzesiek, Stephan. (2019) Rapid determination of general cell status, cell viability, and optimal harvest time in eukaryotic cell cultures by impedance flow cytometry. Applied microbiology and biotechnology, 103 (20). pp. 8619-8629. 2018Sonti, Rajesh and Hertel-Hering, Ines and Lamontanara, Allan Joaquim and Hantschel, Oliver and Grzesiek, Stephan. (2018) ATP Site Ligands Determine the Assembly State of the Abelson Kinase Regulatory Core via the Activation Loop Conformation. Journal of the American Chemical Society, 140 (5). pp. 1863-1869. Franke, Bastian and Opitz, Christian and Isogai, Shin and Grahl, Anne and Delgado, Leonildo and Gossert, Alvar D. and Grzesiek, Stephan. (2018) Production of isotope-labeled proteins in insect cells for NMR. Journal of biomolecular NMR, 71 (3). pp. 173-184. 2017Nesper, Jutta and Hug, Isabelle and Kato, Setsu and Hee, Chee-Seng and Habazettl, Judith Maria and Manfredi, Pablo and Grzesiek, Stephan and Schirmer, Tilman and Emonet, Thierry and Jenal, Urs. (2017) Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators. eLife, 6. e28842. Grzesiek, Stephan. (2017) Kann man die Biologie vorausberechnen? In: natura obscura. Basel, pp. 73-74. 11 February 2016Isogai, Shin and Deupi, Xavier and Opitz, Christian and Heydenreich, Franziska M. and Tsai, Ching-Ju and Brueckner, Florian and Schertler, Gebhard F. X. and Veprintsev, Dmitry B. and Grzesiek, Stephan. (2016) Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor. Nature, 530 (7589). pp. 237-241. January 2016Leung, Hoi Tik Alvin and Bignucolo, Olivier and Aregger, Regula and Dames, Sonja A. and Mazur, Adam and Bernèche, Simon and Grzesiek, Stephan. (2016) A Rigorous and Efficient Method To Reweight Very Large Conformational Ensembles Using Average Experimental Data and To Determine Their Relative Information Content. Journal of chemical theory and computation, 12 (1). pp. 383-394. 2016Aznauryan, Mikayel and Delgado, Leonildo and Soranno, Andrea and Nettels, Daniel and Huang, Jie-Rong and Labhardt, Alexander M. and Grzesiek, Stephan and Schuler, Benjamin. (2016) Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS. Proceedings of the National Academy of Sciences, 113 (37). E5389-E5398. July 2015Opitz, Christian and Isogai, Shin and Grzesiek, Stephan. (2015) An economic approach to efficient isotope labeling in insect cells using homemade 15N-, 13C- and 2H-labeled yeast extracts. Journal of Biomolecular NMR, 62 (3). pp. 373-385. 2015Bignucolo, Olivier and Leung, Hoi Tik Alvin and Grzesiek, Stephan and Bernèche, Simon. (2015) Backbone hydration determines the folding signature of amino acid residues. Journal of the American Chemical Society, Vol. 137, H. 13. pp. 4300-4303. Lamley, Jonathan M. and Lougher, Matthew J. and Sass, Hans Juergen and Rogowski, Marco and Grzesiek, Stephan and Lewandowski, Józef R.. (2015) Unraveling the complexity of protein backbone dynamics with combined (13)C and (15)N solid-state NMR relaxation measurements. Physical Chemistry, Chemical Physics, 17 (34). pp. 21997-22008. 2014Lamley, Jonathan M. and Iuga, Dinu and Oster, Carl and Sass, Hans Juergen and Rogowski, Marco and Oss, Andres and Past, Jaan and Reinhold, Andres and Grzesiek, Stephan and Samoson, Ago and Lewandowski, Józef R.. (2014) Solid-state NMR of a protein in a precipitated complex with a full-length antibody. Journal of the American Chemical Society, Vol. 136, H. 48. pp. 16800-16806. Habazettl, Judith and Allan, Martin and Jensen, Pernille Rose and Sass, Hans-Jürgen and Thompson, Charles J. and Grzesiek, Stephan. (2014) Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system. Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, H. 51 , E5498-5507. 2013Wiktor, Maciej and Morin, Sébastien and Sass, Hans-Jürgen and Kebbel, Fabian and Grzesiek, Stephan. (2013) Biophysical and structural investigation of bacterially expressed and engineered CCR5, a G protein-coupled receptor. Journal of Biomolecular NMR, 55 (1). pp. 79-95. Wiktor, Maciej and Hartley, Oliver and Grzesiek, Stephan. (2013) Characterization of Structure, Dynamics, and Detergent Interactions of the Anti-HIV Chemokine Variant 5P12-RANTES. Biophysical journal, Vol. 105, H. 11. pp. 2586-2597. Vajpai, Navratna and Nisius, Lydia and Wiktor, Maciej and Grzesiek, Stephan. (2013) High-pressure NMR reveals close similarity between cold and alcohol protein denaturation in ubiquitin. Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, H. 5 , E368-376. Nielsen, Gerd and Jonker, Hendrik R. A. and Vajpai, Navratna and Grzesiek, Stephan and Schwalbe, Harald. (2013) Kinase in Motion : Insights into the Dynamic Nature of p38α by High-Pressure NMR Spectroscopic Studies. ChemBioChem, Vol. 14, H. 14. pp. 1799-1806. Skora, Lukasz and Mestan, Jürgen and Fabbro, Doriano and Jahnke, Wolfgang and Grzesiek, Stephan. (2013) NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors. Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, H. 47 , E4437-E4445. Ramón-García, Santiago and Ng, Carol and Jensen, Pernille R. and Dosanjh, Manisha and Burian, Jan and Morris, Rowan P. and Folcher, Marc and Eltis, Lindsay D. and Grzesiek, Stephan and Nguyen, Liem and Thompson, Charles J.. (2013) WhiB7, an Fe-S-dependent Transcription Factor That Activates Species-specific Repertoires of Drug Resistance Determinants in Actinobacteria. Journal of biological chemistry, Vol. 288, H. 48. pp. 34514-34528. 2012Secchi, Massimiliano and Longhi, Renato and Vassena, Lia and Sironi, Francesca and Grzesiek, Stephan and Lusso, Paolo and Vangelista, Luca. (2012) Enhancement of Anti-HIV-1 Activity by Hot Spot Evolution of RANTES-Derived Peptides. Chemistry & Biology, 19 (12). pp. 1579-1588. Markley, John L. and Akutsu, Hideo and Asakura, Tetsuo and Baldus, Marc and Boelens, Rolf and Bonvin, Alexandre and Kaptein, Robert and Bax, Ad and Bezsonova, Irina and Gryk, Michael R. and Hoch, Jeffrey C. and Korzhnev, Dmitry M. and Maciejewski, Mark W. and Case, Dave and Chazin, Walter J. and Cross, Timothy A. and Dames, Sonja and Kessler, Horst and Lange, Oliver and Madl, Tobias and Reif, Bernd and Sattler, Michael and Eliezer, David and Fersht, Alan and Forman-Kay, Julie and Kay, Lewis E. and Fraser, James and Gross, John and Kortemme, Tanja and Sali, Andrej and Fujiwara, Toshimichi and Gardner, Kevin and Luo, Xuelian and Rizo-Rey, Jose and Rosen, Michael and Gil, Roberto R. and Ho, Chien and Rule, Gordon and Gronenborn, Angela M. and Ishima, Rieko and Klein-Seetharaman, Judith and Tang, Pei and van der Wel, Patrick and Xu, Yan and Grzesiek, Stephan and Hiller, Sebastian and Seelig, Joachim and Laue, Ernest D. and Mott, Helen and Nietlispach, Daniel and Barsukov, Igor and Lian, Lu-Yun and Middleton, David and Blumenschein, Tharin and Moore, Geoffrey and Campbell, Iain and Schnell, Jason and Vakonakis, Ioannis John and Watts, Anthony and Conte, Maria R. and Mason, James and Pfuhl, Mark and Sanderson, Mark R. and Craven, Jeremy and Williamson, Michael and Dominguez, Cyril and Roberts, Gordon and Günther, Ulrich and Overduin, Michael and Werner, Joern and Williamson, Philip and Blindauer, Claudia and Crump, Matthew and Driscoll, Paul and Frenkiel, Tom and Golovanov, Alexander and Matthews, Steve and Parkinson, John and Uhrin, Dusan and Williams, Mark and Neuhaus, David and Oschkinat, Hartmut and Ramos, Andres and Shaw, David E. and Steinbeck, Christoph and Vendruscolo, Michele and Vuister, Geerten W. and Walters, Kylie J. and Weinstein, Harel and Wüthrich, Kurt and Yokoyama, Shigeyuki. (2012) In support of the BMRB. Nature Structural and Molecular Biology, 19 (9). pp. 854-860. Nisius, Lydia and Grzesiek, Stephan. (2012) Key stabilizing elements of protein structure identified through pressure and temperature perturbation of its hydrogen bond network. Nature chemistry, Vol. 4, H. 9. pp. 711-717. Van den Bergh, Rafael and Morin, Sébastien and Sass, Hans Jürgen and Grzesiek, Stephan and Vekemans, Marc and Florence, Eric and Thanh Thi Tran, Huyen and Imiru, Rosina Gabriel and Heyndrickx, Leo and Vanham, Guido and De Baetselier, Patrick and Raes, Geert. (2012) Monocytes Contribute to Differential Immune Pressure on R5 versus X4 HIV through the Adipocytokine Visfatin/NAMPT. PLoS ONE, 7 (4). e35074. Gentner, Martin and Allan, Martin G. and Zaehringer, Franziska and Schirmer, Tilman and Grzesiek, Stephan. (2012) Oligomer formation of the bacterial second messenger c-di-GMP : reaction rates and equilibrium constants indicate a monomeric state at physiological concentrations. The journal of the American Chemical Society, 134 (2). pp. 1019-1029. Huang, Jie-rong and Gentner, Martin and Vajpai, Navratna and Grzesiek, Stephan and Blackledge, Martin. (2012) Residual dipolar couplings measured in unfolded proteins are sensitive to amino-acid-specific geometries as well as local conformational sampling. Biochemical Society transactions, Vol. 40, H. 5. pp. 989-994. Huang, Jie-Rong and Gabel, Frank and Jensen, Malene Ringkjøbing and Grzesiek, Stephan and Blackledge, Martin. (2012) Sequence-Specific Mapping of the Interaction between Urea and Unfolded Ubiquitin from Ensemble Analysis of NMR and Small Angle Scattering Data. Journal of the American Chemical Society, Vol. 134, H. 9. pp. 4429-4436. 2011Grzesiek, Stephan and Becker, Edwin D.. (2011) Hydrogen bonding. In: Encyclopedia of NMR, 4. Chichester, pp. 1929-1935. Vuister, Geerten W. and Tjandra, Nico and Shen, Yang and Grishaev, Alex and Grzesiek, Stephan. (2011) Measurement of structural restraints in "A guide to protein NMR spectroscopy". In: Protein NMR spectroscopy : principal techniques and applications. Chichester, p. 351. Lewandowski, Józef R. and Sass, Hans Jürgen and Grzesiek, Stephan and Blackledge, Martin and Emsley, Lyndon. (2011) Site-specific measurement of slow motions in proteins. Journal of the American Chemical Society, 133 (42). pp. 16762-16765. Habazettl, Judith and Allan, Martin G. and Jenal, Urs and Grzesiek, Stephan. (2011) Solution structure of the PilZ domain protein PA4608 complex with cyclic di-GMP identifies charge clustering as molecular readout. Journal of biological chemistry, Vol. 286, H. 16. pp. 14304-14314. Bigalke, Janna M. and Dames, Sonja A. and Blankenfeldt, Wulf and Grzesiek, Stephan and Geyer, Matthias. (2011) Structure and Dynamics of a Stabilized Coiled-Coil Domain in the P-TEFb Regulator Hexim1. Journal of Molecular Biology, 414 (5). pp. 639-653. Dames, Sonja A. and Junemann, Alexander and Sass, Hans J. and Schönichen, André and Stopschinski, Barbara E. and Grzesiek, Stephan and Faix, Jan and Geyer, Matthias. (2011) Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C. Journal of Biological Chemistry, 286 (42). pp. 36907-36920. 2010Schönichen, André and Bigalke, Janna M. and Urbanke, Claus and Grzesiek, Stephan and Dames, Sonja A. and Geyer, Matthias. (2010) A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1. Biochemistry, Vol. 49, H. 14. pp. 3083-3091. Huang, Jie-rong and Grzesiek, Stephan. (2010) Ensemble calculations of unstructured proteins constrained by RDC and PRE data : a case study of urea-denatured ubiquitin. Journal of the American Chemical Society, Vol. 132, H. 2. pp. 694-705. Lewandowski, Józef R. and Sein, Julien and Sass, Hans Jürgen and Grzesiek, Stephan and Blackledge, Martin and Emsley, Lyndon. (2010) Measurement of site-specific 13C spin-lattice relaxation in a crystalline protein. Journal of the American Chemical Society, Vol. 132, H. 24. pp. 8252-8254. Vajpai, Navratna and Gentner, Martin and Huang, Jie-Rong and Blackledge, Martin and Grzesiek, Stephan. (2010) Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings. Journal of the American Chemical Society, Vol. 132, H. 9. pp. 3196-3203. Zhang, Jianming and Adrián, Francisco J. and Jahnke, Wolfgang and Cowan-Jacob, Sandra W. and Li, Allen G. and Iacob, Roxana E. and Sim, Taebo and Powers, John and Dierks, Christine and Sun, Fangxian and Guo, Gui-Rong and Ding, Qiang and Okram, Barun and Choi, Yongmun and Wojciechowski, Amy and Deng, Xianming and Liu, Guoxun and Fendrich, Gabriele and Strauss, André and Vajpai, Navratna and Grzesiek, Stephan and Tuntland, Tove and Liu, Yi and Bursulaya, Badry and Azam, Mohammad and Manley, Paul W. and Engen, John R. and Daley, George Q. and Warmuth, Markus and Gray, Nathanael S.. (2010) Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. Nature, Vol. 463, H. 7280. pp. 501-506. 2008Vajpai, Navratna and Strauss, André and Fendrich, Gabriele and Cowan-Jacob, Sandra W. and Manley, Paul W. and Jahnke, Wolfgang and Grzesiek, Stephan. (2008) Backbone NMR resonance assignment of the Abelson kinase domain in complex with imatinib. Biomolecular NMR Assignments, 2 (1). pp. 41-42. Meier, Sebastian and Blackledge, Martin and Grzesiek, Stephan. (2008) Conformational distributions of unfolded polypeptides from novel NMR techniques. Journal of Chemical Physics, 128 (5). 052204. Cordier, Florence and Nisius, Lydia and Dingley, Andrew J. and Grzesiek, Stephan. (2008) Direct detection of N-H[...]O=C hydrogen bonds in biomolecules by NMR spectroscopy. Nature Protocols, 3 (2). pp. 235-241. Vajpai, Navratna and Strauss, André and Fendrich, Gabriele and Cowan-Jacob, Sandra W. and Manley, Paul W. and Grzesiek, Stephan and Jahnke, Wolfgang. (2008) Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib. Journal of biological chemistry, 283 (26). pp. 18292-18302. 2007Bax, Ad and Grzesiek , Stephan. (2007) Rotating frame Overhauser enhancement spectroscopy. In: Encyclopedia of Nuclear Magnetic Resonance. New York, pp. 245-257. Bang, Eunjung and Häussinger, Daniel and Stetefeld, Jörg and Ahrens, Thomas and Grzesiek, Stephan and Dames, Sonja A.. (2007) ¹H, ¹³C, and ¹⁵N chemical shift assignments for the N-terminal extracellular domain of T-cadherin. Journal of Biomolecular NMR, 38 (2). p. 179. 2003Cordier, Florence and Barfield, Michael and Grzesiek, Stephan. (2003) Direct observation of Calpha-Halpha...O=C hydrogen bonds in proteins by interresidue h3JCalphaC' scalar couplings. Journal of the American Chemical Society, 125 (51). pp. 15750-15751. Grzesiek, Stephan and Cordier, Florence and Dingley, Andrew J.. (2003) Hydrogen Bond Scalar Couplings - A new tool in biomolecular NMR. In: Protein NMR for the Millenium, . Boston, pp. 255-283. 1996Wang, Yun-Xing and Freedberg, Darón I. and Grzesiek, Stephan and Torchia, Dennis A. and Wingfield, Paul T. and Kaufman, Joshua D. and Stahl, Stephen J. and Chang, Chong-Hwan and Hodge, C. Nicholas. (1996) Mapping hydration water molecules in the HIV-1 Protease/DMP323 complex in solution by NMR spectroscopy. Biochemistry, 35 (39). pp. 12694-12704. 1993Grzesiek, Stephan and Anglister, Jacob and Ren, Hao and Bax, Ad. (1993) C-13 Line Narrowing By H-2 Decoupling in H-2/C-13/N-15-Enriched Proteins : application to Triple-Resonance 4d J-Connectivity of Sequential Amides. Journal of the American Chemical Society, 115 (10). pp. 4369-4370. |
