Items where Division is "03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Cancer Immunology and Biology (Zippelius/Rochlitz)"
Number of items at this level: 49. 2024Schmid, Dominic. Counteracting resistance to cancer immunotherapy with neoadjuvant immune checkpoint blockade and targeting of novel regulators of T cell exhaustion. 2024, Doctoral Thesis, University of Basel, Faculty of Science. 2022Kirchhammer, Nicole and Trefny, Marcel P. and Natoli, Marina and Brücher, Dominik and Smith, Sheena N. and Werner, Franziska and Koch, Victoria and Schreiner, David and Bartoszek, Ewelina and Buchi, Mélanie and Schmid, Markus and Breu, Daniel and Hartmann, K. Patricia and Zaytseva, Polina and Thommen, Daniela S. and Läubli, Heinz and Böttcher, Jan P. and Stanczak, Michal A. and Kashyap, Abhishek S. and Plückthun, Andreas and Zippelius, Alfred. (2022) NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity. Science Translational Medicine, 14 (653). abm9043. Lötscher, Jonas and Marti Lindez, Adria-Arnau and Kirchhammer, Nicole and Cribioli, Elisabetta and Giordano, Greta and Trefny, Marcel P. and Lenz, Markus and Rothschild, Sacha I. and Strati, Paolo and Künzli, Marco and Lotter, Claudia and Schenk, Susanne H. and Dehio, Philippe and Löliger, Jordan and Litzler, Ludivine and Schreiner, David and Koch, Victoria and Page, Nicolas and Lee, Dahye and Grählert, Jasmin and Kuzmin, Dmitry and Burgener, Anne-Valérie and Merkler, Doron and Pless, Miklos and Balmer, Maria L. and Reith, Walter and Huwyler, Jörg and Irving, Melita and King, Carolyn G. and Zippelius, Alfred and Hess, Christoph. (2022) Magnesium sensing via LFA-1 regulates CD8+ T cell effector function. Cell, 185. pp. 1-18. 2021Kirchhammer, Nicole. Tumor-targeted immunotherapy using an engineered adenoviral vector platform. 2021, Doctoral Thesis, University of Basel, Faculty of Science. 2020Trefny, Marcel P. and Kaiser, Monika and Stanczak, Michal A. and Herzig, Petra and Savic, Spasenija and Wiese, Mark and Lardinois, Didier and Läubli, Heinz and Uhlenbrock, Franziska and Zippelius, Alfred. (2020) PD-1+ natural killer cells in human non-small cell lung cancer can be activated by PD-1/PD-L1 blockade. Cancer immunology, immunotherapy : CII, 69 (8). pp. 1505-1517. 2017Gautschi, Oliver and Rothschild, Sacha I. and Li, Qiyu and Matter-Walstra, Klazien and Zippelius, Alfred and Betticher, Daniel C. and Früh, Martin and Stahel, Rolf A. and Cathomas, Richard and Rauch, Daniel and Pless, Miklos and Peters, Solange and Froesch, Patrizia and Zander, Thilo and Schneider, Martina and Biaggi, Christine and Mach, Nicolas and Ochsenbein, Adrian F. and Swiss Group for Clinical Cancer, Research. (2017) Bevacizumab Plus Pemetrexed Versus Pemetrexed Alone as Maintenance Therapy for Patients With Advanced Nonsquamous Non-Small-cell Lung Cancer: Update From the Swiss Group for Clinical Cancer Research (SAKK) 19/09 Trial. Clinical Lung Cancer, 18 (3). pp. 303-309. Hammann, Felix and Gotta, Verena and Conen, Katrin and Medinger, Michael and Cesana, Philipp and Rochlitz, Christoph and Taegtmeyer, Anne B.. (2017) Pharmacokinetic interaction between taxanes and amiodarone leading to severe toxicity. British Journal of Clinical Pharmacology, 83 (4). pp. 927-930. Pagani, Olivia and Klingbiel, Dirk and Ruhstaller, Thomas and Nole, Franco and Eppenberger-Castori, Serenella and Oehlschlegel, Christian and Bernhard, Jürg and Brauchli, Peter and Hess, Dagmar and Mamot, Christoph and Munzone, Elisabetta and Pestalozzi, Bernhard C. and Rabaglio, Manuela and Aebi, Stefan and Ribi, Karin and Rochlitz, Christoph and Rothgiesser, Karin and Thürlimann, Beat and von Moos, Roger and Zaman, Khalil and Goldhirsch, Aron and Swiss Group for Clinical Cancer, Research. (2017) Do all patients with advanced HER2 positive breast cancer need upfront-chemo when receiving trastuzumab? Randomized phase III trial SAKK 22/99. Annals of Oncology, 28 (2). pp. 305-312. 2016Conen, Katrin and Hagmann, Raphael and Hess, Viviane and Zippelius, Alfred and Rothschild, Sacha I.. (2016) Incidence and predictors of Bone Metastases (BM) and Skeletal-Related Events (SREs) in Small Cell Lung Cancer (SCLC): A Swiss patient cohort. Journal of Cancer, 7 (14). pp. 2110-2116. Ehrbar, V. and Urech, C. and Alder, J. and Harringer, K. and Zanetti Dallenbach, R. and Rochlitz, C. and Tschudin, S.. (2016) Decision-making about fertility preservation—qualitative data on young cancer patients’ attitudes and needs. Archives of Women's Mental Health, 19 (4). pp. 695-699. Koelzer, Viktor H. and Buser, Tobias and Willi, Niels and Rothschild, Sacha I. and Wicki, Andreas and Schiller, Peter and Cathomas, Gieri and Zippelius, Alfred and Mertz, Kirsten D.. (2016) Grover's-like drug eruption in a patient with metastatic melanoma under ipilimumab therapy. Journal for ImmunoTherapy of Cancer, 4. p. 47. Laubli, H. and Tzankov, A. and Juskevicius, D. and Degen, L. and Rochlitz, C. and Stenner-Liewen, F.. (2016) Lenalidomide monotherapy leads to a complete remission in refractory B-cell post-transplant lymphoproliferative disorder. Leukemia & Lymphoma, 57 (4). pp. 945-948. Muller, P. and Thommen, D. S. and Zippelius, A.. (2016) Agonistic anti-CD40 therapy synergizes with LAG-3-blocking antibodies. Int J Clin Pharmacol Ther, 55 (8). pp. 692-694. Muller, Philipp and Rothschild, Sacha I. and Arnold, Walter and Hirschmann, Petra and Horvath, Lukas and Bubendorf, Lukas and Savic, Spasenija and Zippelius, Alfred. (2016) Metastatic spread in patients with non-small cell lung cancer is associated with a reduced density of tumor-infiltrating T cells. Cancer Immunology Immunotherapy, 65 (1). pp. 1-11. Orleth, Annette and Mamot, Christoph and Rochlitz, Christoph and Ritschard, Reto and Alitalo, Kari and Christofori, Gerhard and Wicki, Andreas. (2016) Simultaneous targeting of VEGF-receptors 2 and 3 with immunoliposomes enhances therapeutic efficacy. Journal of Drug Targeting, 24 (1). pp. 80-89. Rothschild, S. I. and Hagmann, R. and Zippelius, A.. (2016) 92P: Validation of prognostic scores in small cell lung cancer. J Thorac Oncol, 11 (4 Suppl). pp. 96-97. Ruiz, C. and Kustermann, S. and Pietilae, E. and Vlajnic, T. and Baschiera, B. and Arabi, L. and Lorber, T. and Oeggerli, M. and Savic, S. and Obermann, E. and Singer, T. and Rothschild, S. I. and Zippelius, A. and Roth, A. B. and Bubendorf, L.. (2016) Culture and Drug Profiling of Patient Derived Malignant Pleural Effusions for Personalized Cancer Medicine. PLoS One, 11 (8). e0160807. Schlosser, H. A. and Drebber, U. and Kloth, M. and Thelen, M. and Rothschild, S. I. and Haase, S. and Garcia-Marquez, M. and Wennhold, K. and Berlth, F. and Urbanski, A. and Alakus, H. and Schauss, A. and Shimabukuro-Vornhagen, A. and Theurich, S. and Warnecke-Ebertz, U. and Stippel, D. L. and Zippelius, A. and Buttner, R. and Hallek, M. and Holscher, A. H. and Zander, T. and Monig, S. P. and von Bergwelt-Baildon, M.. (2016) Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma. Oncoimmunology, 5 (5). e1100789. Theurich, S. and Rothschild, S. I. and Hoffmann, M. and Fabri, M. and Sommer, A. and Garcia-Marquez, M. and Thelen, M. and Schill, C. and Merki, R. and Schmid, T. and Koeberle, D. and Zippelius, A. and Baues, C. and Mauch, C. and Tigges, C. and Kreuter, A. and Borggrefe, J. and von Bergwelt-Baildon, M. and Schlaak, M.. (2016) Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma. Cancer Immunol Res, 4 (9). pp. 744-754. Thommen, D. and Uhlenbrock, F. and Herzig, P. and Savic Prince, S. and Moersig, W. and Lardinois, D. and Zippelius, A.. (2016) 66P Highly exhausted PD-1hi T cell subsets in human NSCLC are co-defined by the predominant expression of distinct inhibitory receptors and correlate with clinical outcome. Journal of Thoracic Oncology, 11 (4 Suppl). S83. 2015Conen, K. and Mosna-Firlejczyk, K. and Rochlitz, C. and Wicki, A. and Itin, P. and Arnold, A. W. and Gross, M. and Zimmermann, F. and Zippelius, A.. (2015) Vemurafenib-induced radiation recall dermatitis: case report and review of the literature. Dermatology, 230 (1). pp. 1-4. Martin, Kea Simone. Microtubule-depolymerizing agents potentiate anti-tumor immunity by stimulation of dendritic cells. 2015, Doctoral Thesis, University of Basel, Faculty of Science. Meier-Abt, F. and Bentires-Alj, M. and Rochlitz, C.. (2015) Breast Cancer Prevention: Lessons to be Learned from Mechanisms of Early Pregnancy–Mediated Breast Cancer Protection. Cancer Research, 75 (5). pp. 803-807. Wicki, A. and Ritschard, R. and Loesch, U. and Deuster, S. and Rochlitz, C. and Mamot, C.. (2015) Large-scale manufacturing of GMP-compliant anti-EGFR targeted nanocarriers: Production of doxorubicin-loaded anti-EGFR-immunoliposomes for a first-in-man clinical trial. International Journal of Pharmaceutics, 484 (1-2). pp. 8-15. Zaman, K. and Winterhalder, R. and Mamot, C. and Hasler-Strub, U. and Rochlitz, C. and Mueller, A. and Berset, C. and Wiliders, H. and Perey, L. and Rudolf, C. B. and Hawle, H. and Rondeau, S. and Neven, P.. (2015) Fulvestrant with or without selumetinib, a MEK 1/2 inhibitor, in breast cancer progressing after aromatase inhibitor therapy: A multicentre randomised placebo-controlled double-blind phase II trial, SAKK 21/08. European Journal of Cancer, 51 (10). pp. 1212-1220. 2014Conen, Katrin L. and Fischer, Natalie and Hofbauer, Günther F. L. and Shafaeddin-Schreve, Bahar and Winterhalder, Ralph and Rochlitz, Christoph and Zippelius, Alfred. (2014) Cetuximab in metastatic squamous cell cancer of the skin: a Swiss case series. Dermatology, 229 (2). pp. 97-101. Martin, Kea Simone and Müller, Philipp and Schreiner, Jens and Prince, Spasenija Savice and Lardinois, Didier and Heinzelmann-Schwarz, Viola and Thommen, Daniela Stefanie and Zippelius, Alfred. (2014) The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity. Cancer Immunology, Immunotherapy, 63 (9). pp. 925-938. Müller, P. and Martin, K. and Theurich, S. and Schreiner, J. and Savic, S. and Terszowski, G. and Lardinois, D. and Heinzelmann-Schwarz, V. A. and Schlaak, M. and Kvasnicka, H. M. and Spagnoli, G. and Dirnhofer, S. and Speiser, D. E. and von Bergwelt-Baildon, M. and Zippelius, A.. (2014) Microtubule-depolymerizing agents used in antibody-drug conjugates induce antitumor immunity by stimulation of dendritic cells. Cancer Immunology Research, 2 (8). pp. 741-755. Müller, Philipp and Martin, Kea Simone and Theurich, Sebastian and von Bergwelt-Baildon, Michael and Zippelius, Alfred. (2014) Cancer chemotherapy agents target intratumoral dendritic cells to potentiate antitumor immunity. Oncoimmunology, 3 (8). e954460. Romer, A. and Seiler, D. and Marincek, N. and Brunner, P. and Koller, M. T. and Ng, Q. K. T. and Maecke, H. R. and Müller-Brand, J. and Rochlitz, C. and Briel, M. and Schindler, C. and Walter, M. A.. (2014) Somatostatin-based radiopeptide therapy with [(177)Lu-DOTA]-TOC versus [ (90)Y-DOTA]-TOC in neuroendocrine tumours. European journal of nuclear medicine and molecular imaging, Vol. 41, H. 2. pp. 214-222. Sebastian, Martin and Papachristofilou, Alexandros and Weiss, Christian and Früh, Martin and Cathomas, Richard and Hilbe, Wolfgang and Wehler, Thomas and Rippin, Gerd and Koch, Sven D. and Scheel, Birgit and Fotin-Mleczek, Mariola and Heidenreich, Regina and Kallen, Karl-Josef and Gnad-Vogt, Ulrike and Zippelius, Alfred. (2014) Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive(R)) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small cell lung cancer. BMC Cancer, 14. p. 748. Templeton, Arnoud J. and Ribi, Karin and Surber, Christian and Sun, Hong and Hsu Schmitz, Shu-Fang and Beyeler, Michael and Dietrich, Daniel and Borner, Markus and Winkler, Annette and Müller, Andreas and von Rohr, Lukas and Winterhalder, Ralph C. and Rochlitz, Christoph and von Moos, Roger and Zaman, Khalil and Thürlimann, Beat J. K. and Ruhstaller, Thomas and Swiss Group for Clinical Cancer Research Coordinating Center, . (2014) Prevention of palmar-plantar erythrodysesthesia with an antiperspirant in breast cancer patients treated with pegylated liposomal doxorubicin (SAKK 92/08). Breast, 23 (3). pp. 244-249. Tse, B. W. and Collins, A. and Oehler, M. K. and Zippelius, A. and Heinzelmann-Schwarz, V. A.. (2014) Antibody-based immunotherapy for ovarian cancer: where are we at? Annals of oncology, Vol. 25, H. 2. pp. 322-331. Wicki, Andreas and Hermann, Frank and Prêtre, Vincent and Winterhalder, Ralph and Kueng, Marc and von Moos, Roger and Rochlitz, Christoph and Herrmann, Richard. (2014) Pre-existing antihypertensive treatment predicts early increase in blood pressure during bevacizumab therapy: the prospective AVALUE cohort study. Oncol Res Treat, 37 (5). pp. 230-236. 2013Bontognali, S. and Pless, M. and Brutsche, M. H. and Fischer, C. and Rochlitz, C. and Buess, M.. (2013) Analysis of the EGFR mutation status in head and neck squamous cell carcinoma before treatment with Gefitinib. Onkologie, 36 (4). pp. 161-166. Marincek, N. and Jorg, A. C. and Brunner, P. and Schindler, C. and Koller, M. T. and Rochlitz, C. and Muller-Brand, J. and Maecke, H. R. and Briel, M. and Walter, M. A.. (2013) Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors : long-term outcome of a phase I dose escalation study. Journal of translational medicine, Vol. 11 , 17. p. 17. 2012Mamot, C. and Ritschard, R. and Wicki, A. and Kung, W. and Schuller, J. and Herrmann, R. and Rochlitz, C.. (2012) Immunoliposomal delivery of doxorubicin can overcome multidrug resistance mechanisms in EGFR-overexpressing tumor cells. Journal of drug targeting, Vol. 20, H. 5. pp. 422-432. Mamot, C. and Ritschard, R. and Wicki, A. and Stehle, G. and Dieterle, T. and Bubendorf, L. and Hilker, C. and Deuster, S. and Herrmann, R. and Rochlitz, C.. (2012) Tolerability, safety, pharmacokinetics, and efficacy of doxorubicin-loaded anti-EGFR immunoliposomes in advanced solid tumours: a phase 1 dose-escalation study. The Lancet oncology, Vol. 13, H. 12. pp. 1234-1241. Rajski, M. and Vogel, B. and Baty, F. and Rochlitz, C. and Buess, M.. (2012) Global gene expression analysis of the interaction between cancer cells and osteoblasts to predict bone metastasis in breast cancer. PLoS ONE, Vol. 7, H. 1 , e29743. Wicki, A. and Rochlitz, C.. (2012) Targeted therapies in breast cancer. Swiss medical weekly, Vol. 142 , w13550. Wicki, Andreas and Rochlitz, Christoph and Orleth, Annette and Ritschard, Reto and Albrecht, Imke and Herrmann, Richard and Christofori, Gerhard and Mamot, Christoph. (2012) Targeting tumor-associated endothelial cells: anti-VEGFR2 immunoliposomes mediate tumor vessel disruption and inhibit tumor growth. Clinical cancer research, Vol. 18, no. 18. pp. 454-464. 2011Rochlitz, C. and Ruhstaller, T. and Lerch, S. and Spirig, C. and Huober, J. and Suter, T. and Buhlmann, M. and Fehr, M. and Schonenberger, A. and von Moos, R. and Winterhalder, R. and Rauch, D. and Muller, A. and Mannhart-Harms, M. and Herrmann, R. and Cliffe, B. and Mayer, M. and Zaman, K.. (2011) Combination of bevacizumab and 2-weekly pegylated liposomal doxorubicin as first-line therapy for locally recurrent or metastatic breast cancer : a multicenter, single-arm phase II trial (SAKK 24/06). Annals of oncology, Vol. 22, H. 1. pp. 80-85. 2010Burckhart, Tanja and Thiel, Markus and Nishikawa, Hiroyoshi and Wüest, Thomas and Müller, Dafne and Zippelius, Alfred and Ritter, Gerd and Old, Lloyd and Shiku, Hiroshi and Renner, Christoph. (2010) Tumor-specific crosslinking of GITR as costimulation for immunotherapy. Journal of immunotherapy, Vol. 33, H. 9. pp. 925-934. Rajski, M. and Zanetti-Dallenbach, R. and Vogel, B. and Herrmann, R. and Rochlitz, C. and Buess, M.. (2010) IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients. BMC medicine, Vol. 8. p. 1. Speiser, Daniel E. and Schwarz, Katrin and Baumgaertner, Petra and Manolova, Vania and Devevre, Estelle and Sterry, Wolfram and Walden, Peter and Zippelius, Alfred and Conzett, Katrin Baumann and Senti, Gabriela and Voelter, Verena and Cerottini, Jean-Philippe and Guggisberg, David and Willers, Jörg and Geldhof, Christine and Romero, Pedro and Kündig, Thomas and Knuth, Alexander and Dummer, Reinhard and Trefzer, Uwe and Bachmann, Martin F.. (2010) Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients. Journal of immunotherapy, Vol. 33, H. 8. pp. 848-858. 2009Knights, Ashley J. and Nuber, Natko and Thomson, Christopher W. and de la Rosa, Olga and Jäger, Elke and Tiercy, Jean-Marie and van den Broek, Maries and Pascolo, Steve and Knuth, Alexander and Zippelius, Alfred. (2009) Modified tumour antigen-encoding mRNA facilitates the analysis of naturally occurring and vaccine-induced CD4 and CD8 T cells in cancer patients. Cancer immunology, immunotherapy, Vol. 58. pp. 325-338. 2008Curioni-Fontecedro, A. and Knights, A. J. and Tinguely, M. and Nuber, N. and Schneider, C. and Thomson, C. W. and von Boehmer, L. and Bossart, W. and Pahlich, S. and Gehring, H. and Moch, H. and Renner, C. and Knuth, A. and Zippelius, A.. (2008) MAGE-C1/CT7 is the dominant cancer-testis antigen targeted by humoral immune responses in patients with multiple myeloma. Leukemia, Vol. 22, no. 8. pp. 1646-1648. Dummer, R. and Rochlitz, C. and Velu, T. and Acres, B. and Limacher, J. M. and Bleuzen, P. and Lacoste, G. and Slos, P. and Romero, P. and Urosevic, M.. (2008) Intralesional adenovirus-mediated interleukin-2 gene transfer for advanced solid cancers and melanoma. Molecular therapy, Vol. 16, H. 5. pp. 985-994. Tinguely, M. and Jenni, B. and Knights, A. and Lopes, B. and Korol, D. and Rousson, V. and Curioni Fontecedro, A. and Cogliatti, S. B. and Bittermann, A. G. and Schmid, U. and Dommann-Scherrer, C. and Maurer, R. and Renner, C. and Probst-Hensch, N. M. and Moch, H. and Knuth, A. and Zippelius, A.. (2008) MAGE-C1/CT-7 expression in plasma cell myeloma: sub-cellular localization impacts on clinical outcome. Cancer science, Vol. 99, H. 4. pp. 720-725. |