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2022

Ali, A. M. and Gausi, K. and Jongo, S. A. and Kassim, K. R. and Mkindi, C. and Simon, B. and Mtoro, A. T. and Juma, O. A. and Lweno, O. N. and Gwandu, C. H. and Bakari, B. M. and Mbaga, T. A. and Milando, F. A. and Hamad, A. and Shekalaghe, S. A. and Abdulla, S. and Denti, P. and Penny, M. A.. (2022) Population pharmacokinetics of antimalarial naphthoquine in combination with artemisinin in Tanzanian children and adults: dose optimization. Antimicrob Agents Chemother, 66 (5). e0169621.

Golumbeanu, M. and Yang, G. J. and Camponovo, F. and Stuckey, E. M. and Hamon, N. and Mondy, M. and Rees, S. and Chitnis, N. and Cameron, E. and Penny, M. A.. (2022) Leveraging mathematical models of disease dynamics and machine learning to improve development of novel malaria interventions. Infect Dis Poverty, 11. p. 61.

Kelly, S. L. and Le Rütte, E. A. and Richter, M. and Penny, M. A. and Shattock, A. J.. (2022) COVID-19 vaccine booster strategies in light of emerging viral variants: frequency, timing, and target groups. Infect Dis Ther, 11 (5). pp. 2045-2061.

Le Rütte, E. A. and Shattock, A. J. and Chitnis, N. and Kelly, S. L. and Penny, M. A.. (2022) Modelling the impact of Omicron and emerging variants on SARS-CoV-2 transmission and public health burden. Commun Med (Lond), 2. p. 93.

Lee, T. E. and Bonhoeffer, S. and Penny, M. A.. (2022) The competition dynamics of resistant and sensitive infections. Results Phys, 34. p. 105181.

Masserey, T. and Lee, T. and Golumbeanu, M. and Shattock, A. J. and Kelly, S. L. and Hastings, I. M. and Penny, M. A.. (2022) The influence of biological, epidemiological, and treatment factors on the establishment and spread of drug-resistant Plasmodium falciparum. eLife, 11. e7763.

Masserey, T. and Penny, M. A. and Lee, T. E.. (2022) Patient variability in the blood-stage dynamics of Plasmodium falciparum captured by clustering historical data. Malar J, 21. p. 300.

Watson, O. J. and Gao, B. and Nguyen, T. D. and Tran, T. N. and Penny, M. A. and Smith, D. L. and Okell, L. and Aguas, R. and Boni, M. F.. (2022) Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus modelling study. Lancet Microbe, 3 (9). e701-e710.

Yang, G. J. and Shang, L. Y. and Zhou, X. N. and Lee, T. E. and Bi, B. and White, M. and Smith, T. A. and Penny, M. A.. (2022) The empirical support for the radical cure strategy for eliminating Plasmodium vivax in China. BMC Med, 20. p. 17.

Nekkab, N. and Penny, M. A.. (2022) Accelerated development of malaria monoclonal antibodies. Cell Rep Med, 3 (10). p. 100786.

2021

Camponovo, F. and Lee, T. E. and Russell, J. R. and Burgert, L. and Gerardin, J. and Penny, M. A.. (2021) Mechanistic within-host models of the asexual; Plasmodium falciparum; infection: a review and analytical assessment. Malar J, 20. p. 309.

Burgert, L. and Zaloumis, S. and Dini, S. and Marquart, L. and Cao, P. and Cherkaoui, M. and Gobeau, N. and McCarthy, J. and Simpson, J. A. and Möhrle, J. J. and Penny, M. A.. (2021) Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance. Antimicrobial agents and chemotherapy, 65 (4). e01539-20.

Reiker, T. and Golumbeanu, M. and Shattock, A. and Burgert, L. and Smith, T. A. and Filippi, S. and Cameron, E. and Penny, M. A.. (2021) Emulator-based Bayesian optimization for efficient multi-objective calibration of an individual-based model of malaria. Nat Commun, 12. p. 7212.

Stader, F. and Courlet, P. and Kinvig, H. and Penny, M. A. and Decosterd, L. A. and Battegay, M. and Siccardi, M. and Marzolini, C.. (2021) Clinical data combined with modelling and simulation indicate unchanged drug-drug interaction magnitudes in the elderly. Clin Pharmacol Ther, 109 (2). pp. 471-484.

Stader, F. and Courlet, P. and Kinvig, H. and Battegay, M. and Decosterd, L. A. and Penny, M. A. and Siccardi, M. and Marzolini, C.. (2021) Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation. Br J Clin Pharmacol, 87 (2). pp. 458-470.

Shattock, A. J. and Le Rütte, E. A. and Dünner, R. P. and Sen, S. and Kelly, S. L. and Chitnis, N. and Penny, M. A.. (2021) Impact of vaccination and non-pharmaceutical interventions on SARS-CoV-2 dynamics in Switzerland. Epidemics, 38. p. 100535.

Galactionova, K. and Smith, T. A. and Penny, M. A.. (2021) Insights from modelling malaria vaccines for policy decisions: the focus on RTS,S. Malar J, 20. p. 439.

2020

Burgert, Lydia and Rottmann, Matthias and Wittlin, Sergio and Gobeau, Nathalie and Krause, Andreas and Dingemanse, Jasper and Möhrle, Jörg J. and Penny, Melissa A.. (2020) Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development. Scientific reports, 10. p. 4410.

Penny, Melissa A. and Camponovo, Flavia and Chitnis, Nakul and Smith, Thomas A. and Tanner, Marcel. (2020) Future use-cases of vaccines in malaria control and elimination. Parasite epidemiology and control, 10. e00145.

Camponovo, Flavia and Campo, Joseph J. and Le, Timothy Q. and Oberai, Amit and Hung, Christopher and Pablo, Jozelyn V. and Teng, Andy A. and Liang, Xiaowu and Sim, B. Kim Lee and Jongo, Said and Abdulla, Salim and Tanner, Marcel and Hoffman, Stephen L. and Daubenberger, Claudia and Penny, Melissa A.. (2020) Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults. eLife, 9. e53080.

Galactionova, Katya and Velarde, Mar and Silumbe, Kafula and Miller, John and McDonnell, Anthony and Aguas, Ricardo and Smith, Thomas A. and Penny, Melissa A.. (2020) Costing malaria interventions from pilots to elimination programmes. Malaria journal, 19. p. 332.

Yang, G. J. and Liu, Y. and Shang, L. Y. and Zhang, H. W. and Zhou, X. N. and Penny, M. A. and Smith, T. A.. (2020) From Plasmodium vivax outbreak to elimination: lessons learnt from a retrospective analysis of data from Guantang. Malar J, 19. p. 427.

2019

Lee, Tamsin E. and Penny, Melissa A.. (2019) Identifying key factors of the transmission dynamics of drug-resistant malaria. Journal of theoretical biology, 462. pp. 210-220.

Stader, Felix and Penny, Melissa A. and Siccardi, Marco and Marzolini, Catia. (2019) A comprehensive framework for physiologically based pharmacokinetic modelling in Matlab. CPT: Pharmacometrics & Systems Pharmacology. NA.

Meister, Isabel and Assawasuwannakit, Piyanan and Vanobberghen, Fiona and Penny, Melissa A. and Odermatt, Peter and Sayasone, Somphou and Huwyler, Jörg and Tarning, Joel and Keiser, Jennifer. (2019) Pooled population pharmacokinetic analysis of tribendimidine for the treatment of Opisthorchis viverrini infections. Antimicrobial Agents and Chemotherapy, 63 (4). e01391-18.

Dietler, Dominik and Leuenberger, Andrea and Bempong, Nefti-Eboni and Campbell-Lendrum, Diarmid and Cramer, Conradin and Eggen, Rik I. L. and Erismann, Séverine and Ferazzi, Silvia and Flahault, Antoine and Fletcher, Helen A. and Fuhrer, Bernhard and Fuhrimann, Samuel and Greter, Helena and Heerdegen, Anne Christine and Leach, Melissa and Leissing, Anna and Lilje, Jonathan and Penny, Melissa A. and Prytherch, Helen and Staudacher, Philipp and Vounatsou, Penelope and Weiss, Frederik and Wiedemann, Ruth and Winkler, Mirko S. and Zhou, Xiao-Nong and Utzinger, Jürg. (2019) Health in the 2030 Agenda for Sustainable Development : from framework to action, transforming challenges into opportunities. Journal of global health, 9 (2). 020201.

Camponovo, Flavia and Ockenhouse, Chris F. and Lee, Cynthia and Penny, Melissa A.. (2019) Mass campaigns combining antimalarial drugs and anti-infective vaccines as seasonal interventions for malaria control, elimination and prevention of resurgence: a modelling study. BMC infectious diseases, 19. p. 920.

Smith, T. A. and Pemberton-Ross , P. and Penny, M. A. and Chitnis, N.. (2019) Resurgence of malaria infection after mass treatment: a simulation study. Malaria journal, 18. p. 409.

2018

Chitnis, Nakul and Schapira, Allan and Schindler, Christian and Penny, Melissa A. and Smith, Thomas A.. (2018) Mathematical analysis to prioritise strategies for malaria elimination. Journal of theoretical biology, 455. pp. 118-130.

Ali, Ali Mohamed and Penny, Melissa A. and Smith, Thomas A. and Workman, Lesley and Sasi, Philip and Adjei, George O. and Aweeka, Francesca and Kiechel, Jean-René and Jullien, Vincent and Rijken, Marcus J. and McGready, Rose and Mwesigwa, Julia and Kristensen, Kim and Stepniewska, Kasia and Tarning, Joel and Barnes, Karen I. and Denti, Paolo and Wwarn Amodiaquine PK Study Group, . (2018) Population pharmacokinetics of the antimalarial amodiaquine: a pooled analysis to optimize dosing. Antimicrobial agents and chemotherapy, 62 (10). e02193-17.

Stader, Felix and Siccardi, Marco and Battegay, Manuel and Kinvig, Hannah and Penny, Melissa A. and Marzolini, Catia. (2018) Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes. Clinical pharmacokinetics. NA.

2017

Galactionova, Katya and Smith, Thomas A. and de Savigny, Don and Penny, Melissa A.. (2017) State of inequality in malaria intervention coverage in sub-Saharan African countries. BMC medicine, 15. p. 185.

Penny, Melissa and Smith, Thomas. (2017) Plasmodium falciparum mortality in Africa between 1990 and 2015. The New England Journal of Medicine, 376. pp. 2493-2494.