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2020

Dietz, Nikolaus Balthasar and Huber, Markus and Sorg, Isabel and Goepfert, Arnaud and Harms, Alexander and Schirmer, Tilman and Dehio, Christoph. (2020) Structural basis for selective targeting of Rac subfamily GTPases by a bacterial effector protein.

Sorg, Isabel and Schmutz, Christoph and Lu, Yun-Yueh and Fromm, Katja and Siewert, Lena K. and Bögli, Alexandra and Strack, Kathrin and Harms, Alexander and Dehio, Christoph. (2020) A Bartonella effector acts as signaling hub for intrinsic STAT3 activation to trigger anti-inflammatory responses. Cell host & microbe, 27 (3). pp. 476-485.

Horesh, Gal and Fino, Cinzia and Harms, Alexander and Dorman, Matthew J. and Parts, Leopold and Gerdes, Kenn and Heinz, Eva and Thomson, Nicholas R.. (2020) Type II and type IV toxin-antitoxin systems show different evolutionary patterns in the global Klebsiella pneumoniae population. Nucleic Acids Research, 48 (8). pp. 4357-4370.

2019

Balaban, Nathalie Q. and Helaine, Sophie and Lewis, Kim and Ackermann, Martin and Aldridge, Bree and Andersson, Dan I. and Brynildsen, Mark P. and Bumann, Dirk and Camilli, Andrew and Collins, James J. and Dehio, Christoph and Fortune, Sarah M. and Ghigo, Jean-Marc and Hardt, Wolf-Dietrich and Harms, Alexander and Heinemann, Matthias and Hung, Deborah T. and Jenal, Urs and Levin, Bruce R. and Michiels, Jan and Storz, Gisela and Tan, Man-Wah and Tenson, Tanel and Van Melderen, Laurence and Zinkernagel, Annelies. (2019) Definitions and guidelines for research on antibiotic persistence. Nature Reviews Microbiology, 17 (7). pp. 441-448.

Harms, Alexander and Diard, Médéric. (2019) Crowd Controlled-Host Quorum Sensing Drives Phage Decision. Cell host & microbe, 25 (2). pp. 179-181.

Harms, Alexander. (2019) The Biology of Persister Cells in Escherichia coli. In: Persister Cells and Infectious Disease. Cham, pp. 39-57.

2018

Harms, A. and Brodersen, D. E. and Mitarai, N. and Gerdes, K.. (2018) Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology. Molecular cell, 70 (5). pp. 768-784.

Horesh, G. and Harms, A. and Fino, C. and Parts, L. and Gerdes, K. and Heinz, E. and Thomson, N. R.. (2018) SLING: a tool to search for linked genes in bacterial datasets. Nucleic Acids Res, 46 (21). e128.

2017

Harms, Alexander and Fino, Cinzia and Sørensen, Michael A. and Semsey, Szabolcs and Gerdes, Kenn. (2017) Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells. MBio, 8 (6). ii:e01964-17.

2016

Stanger, Frédéric V. and Burmann, Björn M. and Harms, Alexander and Aragão, Hugo and Mazur, Adam and Sharpe, Timothy and Dehio, Christoph and Hiller, Sebastian and Schirmer, Tilman. (2016) Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proceedings of the National Academy of Sciences of the United States of America, 113 (5). E529-E537.

Stanger, Frédéric V. and Harms, Alexander and Dehio, Christoph and Schirmer, Tilman. (2016) Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin. PLoS ONE, 11 (9). e0163654.

Harms, Alexander and Stanger, Frédéric Valentin and Dehio, Christoph. (2016) Biological Diversity and Molecular Plasticity of FIC Domain Proteins. Annual Reviews of Microbiology, 70. pp. 341-360.

Harms, A. and Gerdes, K.. (2016) Back to the Roots: Deep View into the Evolutionary History of ADP-Ribosylation Opened by the DNA-Targeting Toxin-Antitoxin Module DarTG. Molecular cell, 64 (6). pp. 1020-1021.

Harms, A. and Maisonneuve, E. and Gerdes, K.. (2016) Mechanisms of bacterial persistence during stress and antibiotic exposure. Science, 354 (6318). ii:aaf4268.

Stanger, F. V. and Harms, A. and Dehio, C. and Schirmer, T.. (2016) Crystal Structure of the; Escherichia coli; Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin. PLoS One, 11 (9). e0163654.

2015

Harms, Alexander and Stanger, Frédéric Valentin and Scheu, Patrick Daniel and de Jong, Imke Greet and Goepfert, Arnaud and Glatter, Timo and Gerdes, Kenn and Schirmer, Tilman and Dehio, Christoph. (2015) Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology. Cell Reports, 12 (9). pp. 1497-1507.

2014

Pieles, Kathrin and Glatter, Timo and Harms, Alexander and Schmidt, Alexander and Dehio, Christoph. (2014) An experimental strategy for the identification of AMPylation targets from complex protein samples. Proteomics, 14 (9). pp. 1048-1052.

Harms, Alexander. FIC domain toxins are the origin of intra- and inter-kingdom effectors of Bartonella. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

2013

Goepfert, Arnaud and Harms, Alexander and Schirmer, Tilman and Dehio, Christoph. (2013) Type II Toxin-Antitoxin Loci: The fic Family. In: Prokaryotic Toxin-Antitoxins. Heidelberg, pp. 177-187.

2012

Harms, Alexander and Dehio, Christoph. (2012) Intruders below the Radar : Molecular Pathogenesis of Bartonella spp. Clinical microbiology reviews, Vol. 25, H. 1. pp. 42-78.

Engel, Philipp and Goepfert, Arnaud and Stanger, Frédéric V. and Harms, Alexander and Schmidt, Alexander and Schirmer, Tilman and Dehio, Christoph. (2012) Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482 (7383). pp. 107-110.

Harms, Alexander and Dehio, Christoph. (2012) Intruders below the radar: molecular pathogenesis of Bartonella spp. Clinical microbiology reviews, 25 (1). pp. 42-78.