Shaidullina, Aisylu and Harms, Alexander. (2022) Antiviral death punch by ADP-ribosylating bacterial toxins. Trends in Microbiology, 30 (10). pp. 920-921.
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Abstract
Toxin-antitoxin systems can defend bacteria against phages by shutting down infected cells, but the links between their molecular mechanisms and biological functions have remained underexplored. LeRoux et al. now show how the DNA-targeting ADP-ribosylation activity of DarTG impairs phage replication but is overcome by dedicated viral inhibitors and evolved tolerance.
| Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Infection Biology > Molecular Microbiology (Jenal) 05 Faculty of Science > Departement Biozentrum > Growth & Development > Molecular Microbiology (Jenal) 05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Molecular Microbiology (Harms) |
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| UniBasel Contributors: | Harms, Alexander and Shaidullina, Aisylu |
| Item Type: | Article |
| Article Subtype: | Research Article |
| Publisher: | Elsevier |
| ISSN: | 0966-842X |
| e-ISSN: | 1878-4380 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Language: | English |
| Identification Number: |
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| edoc DOI: | |
| Last Modified: | 22 Aug 2023 01:30 |
| Deposited On: | 14 Sep 2022 09:43 |
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