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2022

Lötscher, Jonas and Marti Lindez, Adria-Arnau and Kirchhammer, Nicole and Cribioli, Elisabetta and Giordano, Greta and Trefny, Marcel P. and Lenz, Markus and Rothschild, Sacha I. and Strati, Paolo and Künzli, Marco and Lotter, Claudia and Schenk, Susanne H. and Dehio, Philippe and Löliger, Jordan and Litzler, Ludivine and Schreiner, David and Koch, Victoria and Page, Nicolas and Lee, Dahye and Grählert, Jasmin and Kuzmin, Dmitry and Burgener, Anne-Valérie and Merkler, Doron and Pless, Miklos and Balmer, Maria L. and Reith, Walter and Huwyler, Jörg and Irving, Melita and King, Carolyn G. and Zippelius, Alfred and Hess, Christoph. (2022) Magnesium sensing via LFA-1 regulates CD8+ T cell effector function. Cell, 185. pp. 1-18.

Kirchhammer, Nicole and Trefny, Marcel P. and Natoli, Marina and Brücher, Dominik and Smith, Sheena N. and Werner, Franziska and Koch, Victoria and Schreiner, David and Bartoszek, Ewelina and Buchi, Mélanie and Schmid, Markus and Breu, Daniel and Hartmann, K. Patricia and Zaytseva, Polina and Thommen, Daniela S. and Läubli, Heinz and Böttcher, Jan P. and Stanczak, Michal A. and Kashyap, Abhishek S. and Plückthun, Andreas and Zippelius, Alfred. (2022) NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity. Science Translational Medicine, 14 (653). abm9043.

2020

Trefny, Marcel P. and Kaiser, Monika and Stanczak, Michal A. and Herzig, Petra and Savic, Spasenija and Wiese, Mark and Lardinois, Didier and Läubli, Heinz and Uhlenbrock, Franziska and Zippelius, Alfred. (2020) PD-1+ natural killer cells in human non-small cell lung cancer can be activated by PD-1/PD-L1 blockade. Cancer immunology, immunotherapy : CII, 69 (8). pp. 1505-1517.

2017

Gautschi, Oliver and Rothschild, Sacha I. and Li, Qiyu and Matter-Walstra, Klazien and Zippelius, Alfred and Betticher, Daniel C. and Früh, Martin and Stahel, Rolf A. and Cathomas, Richard and Rauch, Daniel and Pless, Miklos and Peters, Solange and Froesch, Patrizia and Zander, Thilo and Schneider, Martina and Biaggi, Christine and Mach, Nicolas and Ochsenbein, Adrian F. and Swiss Group for Clinical Cancer, Research. (2017) Bevacizumab Plus Pemetrexed Versus Pemetrexed Alone as Maintenance Therapy for Patients With Advanced Nonsquamous Non-Small-cell Lung Cancer: Update From the Swiss Group for Clinical Cancer Research (SAKK) 19/09 Trial. Clinical Lung Cancer, 18 (3). pp. 303-309.

2016

Thommen, D. and Uhlenbrock, F. and Herzig, P. and Savic Prince, S. and Moersig, W. and Lardinois, D. and Zippelius, A.. (2016) 66P Highly exhausted PD-1hi T cell subsets in human NSCLC are co-defined by the predominant expression of distinct inhibitory receptors and correlate with clinical outcome. Journal of Thoracic Oncology, 11 (4 Suppl). S83.

Theurich, S. and Rothschild, S. I. and Hoffmann, M. and Fabri, M. and Sommer, A. and Garcia-Marquez, M. and Thelen, M. and Schill, C. and Merki, R. and Schmid, T. and Koeberle, D. and Zippelius, A. and Baues, C. and Mauch, C. and Tigges, C. and Kreuter, A. and Borggrefe, J. and von Bergwelt-Baildon, M. and Schlaak, M.. (2016) Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma. Cancer Immunol Res, 4 (9). pp. 744-754.

Schlosser, H. A. and Drebber, U. and Kloth, M. and Thelen, M. and Rothschild, S. I. and Haase, S. and Garcia-Marquez, M. and Wennhold, K. and Berlth, F. and Urbanski, A. and Alakus, H. and Schauss, A. and Shimabukuro-Vornhagen, A. and Theurich, S. and Warnecke-Ebertz, U. and Stippel, D. L. and Zippelius, A. and Buttner, R. and Hallek, M. and Holscher, A. H. and Zander, T. and Monig, S. P. and von Bergwelt-Baildon, M.. (2016) Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma. Oncoimmunology, 5 (5). e1100789.

Ruiz, C. and Kustermann, S. and Pietilae, E. and Vlajnic, T. and Baschiera, B. and Arabi, L. and Lorber, T. and Oeggerli, M. and Savic, S. and Obermann, E. and Singer, T. and Rothschild, S. I. and Zippelius, A. and Roth, A. B. and Bubendorf, L.. (2016) Culture and Drug Profiling of Patient Derived Malignant Pleural Effusions for Personalized Cancer Medicine. PLoS One, 11 (8). e0160807.

Rothschild, S. I. and Hagmann, R. and Zippelius, A.. (2016) 92P: Validation of prognostic scores in small cell lung cancer. J Thorac Oncol, 11 (4 Suppl). pp. 96-97.

Muller, P. and Thommen, D. S. and Zippelius, A.. (2016) Agonistic anti-CD40 therapy synergizes with LAG-3-blocking antibodies. Int J Clin Pharmacol Ther, 55 (8). pp. 692-694.

Muller, Philipp and Rothschild, Sacha I. and Arnold, Walter and Hirschmann, Petra and Horvath, Lukas and Bubendorf, Lukas and Savic, Spasenija and Zippelius, Alfred. (2016) Metastatic spread in patients with non-small cell lung cancer is associated with a reduced density of tumor-infiltrating T cells. Cancer Immunology Immunotherapy, 65 (1). pp. 1-11.

Koelzer, Viktor H. and Buser, Tobias and Willi, Niels and Rothschild, Sacha I. and Wicki, Andreas and Schiller, Peter and Cathomas, Gieri and Zippelius, Alfred and Mertz, Kirsten D.. (2016) Grover's-like drug eruption in a patient with metastatic melanoma under ipilimumab therapy. Journal for ImmunoTherapy of Cancer, 4. p. 47.

Conen, Katrin and Hagmann, Raphael and Hess, Viviane and Zippelius, Alfred and Rothschild, Sacha I.. (2016) Incidence and predictors of Bone Metastases (BM) and Skeletal-Related Events (SREs) in Small Cell Lung Cancer (SCLC): A Swiss patient cohort. Journal of Cancer, 7 (14). pp. 2110-2116.

2015

Conen, K. and Mosna-Firlejczyk, K. and Rochlitz, C. and Wicki, A. and Itin, P. and Arnold, A. W. and Gross, M. and Zimmermann, F. and Zippelius, A.. (2015) Vemurafenib-induced radiation recall dermatitis: case report and review of the literature. Dermatology, 230 (1). pp. 1-4.

2014

Tse, B. W. and Collins, A. and Oehler, M. K. and Zippelius, A. and Heinzelmann-Schwarz, V. A.. (2014) Antibody-based immunotherapy for ovarian cancer: where are we at? Annals of oncology, Vol. 25, H. 2. pp. 322-331.

Müller, P. and Martin, K. and Theurich, S. and Schreiner, J. and Savic, S. and Terszowski, G. and Lardinois, D. and Heinzelmann-Schwarz, V. A. and Schlaak, M. and Kvasnicka, H. M. and Spagnoli, G. and Dirnhofer, S. and Speiser, D. E. and von Bergwelt-Baildon, M. and Zippelius, A.. (2014) Microtubule-depolymerizing agents used in antibody-drug conjugates induce antitumor immunity by stimulation of dendritic cells. Cancer Immunology Research, 2 (8). pp. 741-755.

Martin, Kea Simone and Müller, Philipp and Schreiner, Jens and Prince, Spasenija Savice and Lardinois, Didier and Heinzelmann-Schwarz, Viola and Thommen, Daniela Stefanie and Zippelius, Alfred. (2014) The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity. Cancer Immunology, Immunotherapy, 63 (9). pp. 925-938.

Conen, Katrin L. and Fischer, Natalie and Hofbauer, Günther F. L. and Shafaeddin-Schreve, Bahar and Winterhalder, Ralph and Rochlitz, Christoph and Zippelius, Alfred. (2014) Cetuximab in metastatic squamous cell cancer of the skin: a Swiss case series. Dermatology, 229 (2). pp. 97-101.

Sebastian, Martin and Papachristofilou, Alexandros and Weiss, Christian and Früh, Martin and Cathomas, Richard and Hilbe, Wolfgang and Wehler, Thomas and Rippin, Gerd and Koch, Sven D. and Scheel, Birgit and Fotin-Mleczek, Mariola and Heidenreich, Regina and Kallen, Karl-Josef and Gnad-Vogt, Ulrike and Zippelius, Alfred. (2014) Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive(R)) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small cell lung cancer. BMC Cancer, 14. p. 748.

Müller, Philipp and Martin, Kea Simone and Theurich, Sebastian and von Bergwelt-Baildon, Michael and Zippelius, Alfred. (2014) Cancer chemotherapy agents target intratumoral dendritic cells to potentiate antitumor immunity. Oncoimmunology, 3 (8). e954460.

2010

Burckhart, Tanja and Thiel, Markus and Nishikawa, Hiroyoshi and Wüest, Thomas and Müller, Dafne and Zippelius, Alfred and Ritter, Gerd and Old, Lloyd and Shiku, Hiroshi and Renner, Christoph. (2010) Tumor-specific crosslinking of GITR as costimulation for immunotherapy. Journal of immunotherapy, Vol. 33, H. 9. pp. 925-934.

Speiser, Daniel E. and Schwarz, Katrin and Baumgaertner, Petra and Manolova, Vania and Devevre, Estelle and Sterry, Wolfram and Walden, Peter and Zippelius, Alfred and Conzett, Katrin Baumann and Senti, Gabriela and Voelter, Verena and Cerottini, Jean-Philippe and Guggisberg, David and Willers, Jörg and Geldhof, Christine and Romero, Pedro and Kündig, Thomas and Knuth, Alexander and Dummer, Reinhard and Trefzer, Uwe and Bachmann, Martin F.. (2010) Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients. Journal of immunotherapy, Vol. 33, H. 8. pp. 848-858.

2009

Knights, Ashley J. and Nuber, Natko and Thomson, Christopher W. and de la Rosa, Olga and Jäger, Elke and Tiercy, Jean-Marie and van den Broek, Maries and Pascolo, Steve and Knuth, Alexander and Zippelius, Alfred. (2009) Modified tumour antigen-encoding mRNA facilitates the analysis of naturally occurring and vaccine-induced CD4 and CD8 T cells in cancer patients. Cancer immunology, immunotherapy, Vol. 58. pp. 325-338.

2008

Tinguely, M. and Jenni, B. and Knights, A. and Lopes, B. and Korol, D. and Rousson, V. and Curioni Fontecedro, A. and Cogliatti, S. B. and Bittermann, A. G. and Schmid, U. and Dommann-Scherrer, C. and Maurer, R. and Renner, C. and Probst-Hensch, N. M. and Moch, H. and Knuth, A. and Zippelius, A.. (2008) MAGE-C1/CT-7 expression in plasma cell myeloma: sub-cellular localization impacts on clinical outcome. Cancer science, Vol. 99, H. 4. pp. 720-725.

Curioni-Fontecedro, A. and Knights, A. J. and Tinguely, M. and Nuber, N. and Schneider, C. and Thomson, C. W. and von Boehmer, L. and Bossart, W. and Pahlich, S. and Gehring, H. and Moch, H. and Renner, C. and Knuth, A. and Zippelius, A.. (2008) MAGE-C1/CT7 is the dominant cancer-testis antigen targeted by humoral immune responses in patients with multiple myeloma. Leukemia, Vol. 22, no. 8. pp. 1646-1648.