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Mayer, C. E. and Zuklys, S. and Zhanybekova, S. and Ohigashi, I. and Teh, H. Y. and Sansom, S. N. and Shikama-Dorn, N. and Hafen, K. and Macaulay, I. C. and Deadman, M. E. and Ponting, C. P. and Takahama, Y. and Hollander, G. A.. (2016) Dynamic spatio-temporal contribution of single beta5t+ cortical epithelial precursors to the thymus medulla. Eur J Immunol, 46 (4). pp. 846-856.

Zuklys, S. and Handel, A. and Zhanybekova, S. and Govani, F. and Keller, M. and Maio, S. and Mayer, C. E. and Teh, H. Y. and Hafen, K. and Gallone, G. and Barthlott, T. and Ponting, C. P. and Hollander, G. A.. (2016) Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells. Nat Immunol, 17 (10). pp. 1206-1215.

Barthlott, Thomas and Bosch, Angela J. and Berkemeier, Caroline and Nogales-Cadenas, Rubén and Jeker, Lukas T. and Keller, Marcel P. and Pascual-Montano, Alberto and Hollander, Georg A.. (2015) A subpopulation of CD103(pos) ICOS(pos) Treg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stage. European Journal of Immunology, 45 (6). pp. 1760-1771.

Sansom, Stephen N. and Shikama-Dorn, Noriko and Zhanybekova, Saule and Nusspaumer, Gretel and Macaulay, Iain C. and Deadman, Mary E. and Heger, Andreas and Ponting, Chris P. and Holländer, Georg A.. (2014) Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia. Genome Research, 24 (12). pp. 1918-1931.

Hauri-Hohl, M. and Zuklys, S. and Holländer, G. A. and Ziegler, S. F.. (2014) A regulatory role for TGF-beta signaling in the establishment and function of the thymic medulla. Nature immunology, 15 (6). pp. 554-561.

Dertschnig, Simone and Nusspaumer, Gretel and Ivanek, Robert and Hauri-Hohl, Mathias M. and Holländer, Georg A. and Krenger, Werner. (2013) Epithelial cytoprotection sustains ectopic expression of tissue-restricted antigens in the thymus during murine acute GVHD. Blood, 122 (5). pp. 837-841.

Lopez-Rios, J. and Speziale, D. and Robay, D. and Scotti, M. and Osterwalder, M. and Nusspaumer, G. and Galli, A. and Hollander, G. A. and Kmita, M. and Zeller, R.. (2012) GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. Developmental cell, Vol. 22, H. 4. pp. 837-848.

Krenger, Werner and Blazar, Bruce R. and Holländer, Georg A.. (2011) Thymic T-cell development in allogeneic stem cell transplantation. Blood : the journal of the American Society of Hematology, Vol. 117, H. 25. pp. 6768-6776.

Thakar, Saurabh and Chandra, Preeti and Hollander, Gerald and Lichstein, Edgar. (2011) Electrocardiographic changes in takotsubo cardiomyopathy. Pace, Vol. 34, H. 10. pp. 1278-1282.

Papadopoulou, Aikaterini S. and Dooley, James and Linterman, Michelle A. and Pierson, Wim and Ucar, Olga and Kyewski, Bruno and Zuklys, Saulius and Hollander, Georg A. and Matthys, Patrick and Gray, Daniel H. D. and De Strooper, Bart and Liston, Adrian. (2011) The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor. Nature Immunology, Vol. 13, H. 2. pp. 181-187.

Lei, Y. and Ripen, A. M. and Ishimaru, N. and Ohigashi, I. and Nagasawa, T. and Jeker, L. T. and Bosl, M. R. and Hollander, G. A. and Hayashi, Y. and Malefyt Rde, W. and Nitta, T. and Takahama, Y.. (2011) Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. Journal of experimental medicine, Vol. 208, H. 2. pp. 383-394.

Vroegindeweij, Eric and Crobach, Stijn and Itoi, Manami and Satoh, Rumi and Zuklys, Saulius and Happe, Christiane and Germeraad, Wilfred T. V. and Cornelissen, Jan J. and Cupedo, Tom and Holländer, Georg A. and Kawamoto, Hiroshi and van Ewijk, Willem. (2010) Thymic cysts originate from Foxn1 positive thymic medullary epithelium. Molecular immunology, Vol. 47, H. 5. pp. 1106-1113.

Kenins, Linda and Gill, Jason W. and Holländer, Georg A. and Wodnar-Filipowicz, Aleksandra. (2010) Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis. European Journal of Immunology, Vol. 40, H. 1. pp. 81-90.

Gossens, Klaus and Naus, Silvia and Holländer, Georg A. and Ziltener, Hermann J.. (2010) Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity. PLoS ONE, Vol. 5, H. 9 , e12766.

Kelly, Ryan M. and Goren, Emily M. and Taylor, Patricia A. and Mueller, Scott N. and Stefanski, Heather E. and Osborn, Mark J. and Scott, Hamish S. and Komarova, Elena A. and Gudkov, Andrei V. and Holländer, Georg A. and Blazar, Bruce R.. (2010) Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation. Blood, Vol. 115, H. 5. pp. 1088-1097.

Saade, Murielle and Irla, Magali and Yammine, Miriam and Boulanger, Nicolas and Victorero, Geneviève and Vincentelli, Renaud and Penninger, Josef M. and Holländer, Georg A. and Chauvet, Sophie and Nguyen, Catherine. (2010) Spatial (Tbata) expression in mature medullary thymic epithelial cells. European Journal of Immunology, Vol. 40, H. 2. pp. 530-538.

Fayard, Elisabeth and Moncayo, Gerald and Hemmings, Brian A. and Holländer, Georg A.. (2010) Phosphatidylinositol 3-kinase signaling in thymocytes : the need for stringent control. Science signaling, Vol. 3, H. 135 , re5.

Irla, Magali and Hollander, Georg and Reith, Walter. (2010) Control of central self-tolerance induction by autoreactive CD4+ thymocytes. Trends in immunology, Vol. 31, H. 2. pp. 71-79.

Holländer, Georg A. and Krenger, Werner and Blazar, Bruce R.. (2010) Emerging strategies to boost thymic function. Current opinion in pharmacology, Vol. 10, H. 4. pp. 443-453.

Krenger, Werner and Holländer, Georg A.. (2010) The role of the thymus in allogeneic hematopoietic stem cell transplantation. Swiss medical weekly, Vol. 140 , w13051.

Zuklys, Saulius and Gill, Jason and Keller, Marcel P. and Hauri-Hohl, Mathias and Zhanybekova, Saule and Balciunaite, Gina and Na, Kyung-Jae and Jeker, Lukas T. and Hafen, Katrin and Tsukamoto, Noriyuki and Amagai, Takashi and Taketo, Makoto M. and Krenger, Werner and Holländer, Georg A.. (2009) Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. Journal of immunology : official journal of the American Association of Immunologists, Vol. 182. pp. 2997-3007.

Holländer, G. A. and Peterson, P.. (2009) Learning to be tolerant : how T cells keep out of trouble. Journal of internal medicine, Vol. 265, H. 5. pp. 541-561.

Takahama, Yousuke and Saito, Takashi and Kawamoto, Hiroshi and Itoi, Manami and Boyd, Richard L. and Chidgey, Ann and Zamoyska, Rose and Holländer, Georg A. and Anderson, Graham and Taylor, Naomi and Petrie, Howard T. and Nikolich-Zugich, Janko. (2009) The Global Thymus Network: past, present and future. Trends in immunology, Vol. 30, H. 5. pp. 191-192.

Shikama, Noriko and Nusspaumer, Gretel and Holländer, Georg A.. (2009) Clearing the AIRE : on the pathophysiological basis of the autoimmune polyendocrinopathy syndrome type-1. Endocrinology and metabolism clinics of North America, Vol. 38, H. 2 , S. 273-288, vii.

Heikenwalder, M. and Prinz, M. and Zeller, N. and Lang, K. S. and Junt, T. and Rossi, S. and Tumanov, A. and Schmidt, H. and Priller, J. and Flatz, L. and Rülicke, T. and Macpherson, A. J. and Holländer, G. A. and Nedospasov, S. A. and Aguzzi, A.. (2008) Overexpression of lymphotoxin in T cells induces fulminant thymic involution. American Journal of Pathology, Vol. 172, no. 6. pp. 1555-1570.

Kenins, L. and Gill, J. W. and Boyd, R. L. and Holländer, G. A. and Wodnar-Filipowicz, A.. (2008) Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation. Journal of experimental medicine, Vol. 205, H. 3. pp. 523-531.

Alimohammadi, M. and Björklund, P. and Hallgren, A. and Pöntynen, N. and Szinnai, G. and Shikama, N. and Keller, M. P. and Ekwall, O. and Kinkel, S. A. and Husebye, E. S. and Gustafsson, J. and Rorsman, F. and Peltonen, L. and Betterle, C. and Perheentupa, J. and Akerström, G. and Westin, G. and Scott, H. S. and Holländer, G. A. and Kämpe, O.. (2008) Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen. The New England journal of medicine, Vol. 358, H. 10. pp. 1018-1028.

Holländer, G. A.. (2008) Lymphoid reconstitution following hematopoietic stem cell transplantation : of mice and men: progress made in HSCT immunobiology. Seminars in immunopathology, Vol. 30, no. 4. pp. 369-370.

Hozumi, K. and Mailhos, C. and Negishi, N. and Hirano, K. and Yahata, T. and Ando, K. and Zuklys, S. and Holländer, G. A. and Shima, D. T. and Habu, S.. (2008) Delta-like 4 is indispensable in thymic environment specific for T cell development. Journal of experimental medicine, Vol. 205, H. 11. pp. 2507-2513.

Irla, M. and Hugues, S. and Gill, J. and Nitta, T. and Hikosaka, Y. and Williams, I. R. and Hubert, F. X. and Scott, H. S. and Takahama, Y. and Holländer, G. A. and Reith, W.. (2008) Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity. Immunity, Vol. 29, H. 3. pp. 451-463.

Krenger, W. and Holländer, G. A.. (2008) The immunopathology of thymic GVHD. Seminars in immunopathology, Vol. 30, no. 4. pp. 439-456.

Guimond, M. and Leonard, W. J. and Spolski, R. and Rossi, S. W. and Veenstra, R. G. and Hollander, G. A. and Mackall, C. L. and Blazar, B. R.. (2008) Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor. Blood, Vol. 111, H. 2. pp. 969-970.

Krenger, W. and Holländer, G. A.. (2008) The thymus in GVHD pathophysiology. Best practice & research. Clinical haematology, Vol. 21, H. 2. pp. 119-128.

Jeker, Lukas Thabo and Barthlott, Thomas and Keller, Marcel P. and Zuklys, Saulius and Hauri-Hohl, Mathias Martin and Deng, Chu-Xia and Holländer, Georg A.. (2008) Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells. Blood, 112 (9). pp. 3688-3695.

Hauri-Hohl, Mathias Martin and Zuklys, Saulius and Keller, Marcel P. and Jeker, Lukas T. and Barthlott, Thomas and Moon, Anne M. and Roes, Jürgen and Holländer, Georg A.. (2008) TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution. Blood, 112 (3). pp. 626-634.

Kelly, Ryan M. and Highfill, Steven L. and Panoskaltsis-Mortari, Angela and Taylor, Patricia A. and Boyd, Richard L. and Holländer, Georg A. and Blazar, Bruce R.. (2008) Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation. Blood, 111 (12). pp. 5734-5744.