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Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity

Gossens, Klaus and Naus, Silvia and Holländer, Georg A. and Ziltener, Hermann J.. (2010) Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity. PLoS ONE, Vol. 5, H. 9 , e12766.

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Official URL: http://edoc.unibas.ch/dok/A6006323

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Abstract

Thymopoiesis requires thymocyte-stroma interactions and proteases that promote cell migration by degrading extracellular matrix and releasing essential cytokines and chemokines. A role for several members of the A Disintegrin and Metalloprotease (ADAM) family in T cell development has been reported in the past.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Children's Hospital > Pediatric Immunology (Holländer)
UniBasel Contributors:Holländer, Georg
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Public Library of Science
e-ISSN:1932-6203
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:31 Aug 2018 06:40
Deposited On:24 May 2013 09:06

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