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2020

Baas, Inge and Delvasto-Nuñez, Laura and Ligthart, Peter and Brouwer, Conny and Folman, Claudia and Reis, Edimara S. and Ricklin, Daniel and Lambris, John D. and Wouters, Diana and de Haas, Masja and Jongerius, Ilse and Zeerleder, Sacha S.. (2020) Complement C3 inhibition by compstatin Cp40 prevents intra- and extravascular hemolysis of red blood cells. Haematologica, 105 (2). e57-e60.

Olcina, Monica M. and Kim, Ryan K. and Balanis, Nikolas G. and Li, Caiyun Grace and von Eyben, Rie and Graeber, Thomas G. and Ricklin, Daniel and Stucki, Manuel and Giaccia, Amato J.. (2020) Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis. iScience, 23 (10). p. 101594.

Hughes, Sarah and Gumas, Justin and Lee, Rebecca and Rumano, Merita and Berger, Nadja and Gautam, Avneesh Kumar and Sfyroera, Georgia and Chan, Anna Lorena and Gnanaguru, Gopalan and Connor, Kip M. and Kim, Benjamin J. and Dunaief, Joshua L. and Ricklin, Daniel and Hajishengallis, George and Yancopoulou, Despina and Reis, Edimara S. and Mastellos, Dimitrios C. and Lambris, John D.. (2020) Prolonged intraocular residence and retinal tissue distribution of a fourth-generation compstatin-based C3 inhibitor in non-human primates. Clinical Immunology, 214. p. 108391.

2019

Epper, Bettina. (12 January 2019) Dossier "Wirkstoffe" - Vom Molekül zum Medikament. Drogistenstern, (12/19-1/20). pp. 6-16.

van Griensven, Martijn and Ricklin, Daniel and Denk, Stephanie and Halbgebauer, Rebecca and Braun, Christian K. and Schultze, Anke and Hönes, Felix and Koutsogiannaki, Sofia and Primikyri, Alexandra and Reis, Edimara and Messerer, David and Hafner, Sebastian and Radermacher, Peter and Biglarnia, Ali-Reza and Resuello, Ranillo R. G. and Tuplano, Joel V. and Mayer, Benjamin and Nilsson, Kristina and Nilsson, Bo and Lambris, John D. and Huber-Lang, Markus. (2019) Protective Effects of the Complement Inhibitor Compstatin CP40 in Hemorrhagic Shock. Shock, 51 (1). pp. 78-87.

Mastellos, Dimitrios C. and Blom, Anna M. and Connolly, E. Sander and Daha, Mohamed R. and Geisbrecht, Brian V. and Ghebrehiwet, Berhane and Gros, Piet and Hajishengallis, George and Holers, V. Michael and Huber-Lang, Markus and Kinoshita, Taroh and Mollnes, Tom E. and Montgomery, Robert A. and Morgan, B. Paul and Nilsson, Bo and Pio, Ruben and Ricklin, Daniel and Risitano, Antonio M. and Taylor, Ronald P. and Mantovani, Alberto and Ioannidis, John P. A. and Lambris, John D.. (2019) 'Stealth' corporate innovation: an emerging threat for therapeutic drug development. Nature immunology, 20 (11). pp. 1409-1413.

Mastellos, Dimitrios C. and Ricklin, Daniel and Lambris, John D.. (2019) Clinical promise of next-generation complement therapeutics. Nature reviews. Drug discovery, 18 (9). pp. 707-729.

Lombardi, Elisabetta and Matte, Alessandro and Risitano, Antonio M. and Ricklin, Daniel and Lambris, John D. and De Zanet, Denise and Jokiranta, Sakari T. and Martinelli, Nicola and Scambi, Cinzia and Salvagno, Gianluca and Bisoffi, Zeno and Colato, Chiara and Siciliano, Angela and Bortolami, Oscar and Mazzuccato, Mario and Zorzi, Francesco and De Marco, Luigi and De Franceschi, Lucia. (2019) Factor H interferes with the adhesion of sickle red cells to vascular endothelium: a novel disease-modulating molecule. Haematologica, 104 (5). pp. 919-928.

2018

Reis, Edimara S. and Mastellos, Dimitrios C. and Ricklin, Daniel and Mantovani, Alberto and Lambris, John D.. (2018) Complement in cancer: untangling an intricate relationship. Nature reviews. Immunology, 18 (1). pp. 5-18.

Ricklin, Daniel and Mastellos, Dimitrios C. and Reis, Edimara S. and Lambris, John D.. (2018) The renaissance of complement therapeutics. Nature Reviews Nephrology , 14 (1). pp. 26-47.

Yuan, Xiaopeng and Yang, Mingjuan and Chen, Xiang and Zhang, Xuhua and Sukhadia, Shrey and Musolino, Najia and Bao, Huijing and Chen, Tingtao and Xu, Chen and Wang, Qirui and Santoro, Stephen and Ricklin, Daniel and Hu, Jia and Lin, Ruihe and Yang, Wei and Li, Zhijun and Qin, Weijun and Zhao, Aizhi and Scholler, Nathalie and Coukos, George. (2018) Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy. Cancer immunology, immunotherapy : CII, 67 (2). pp. 329-339.

Harris, Claire L. and Pouw, Richard B. and Kavanagh, David and Sun, Ruyue and Ricklin, Daniel. (2018) Developments in anti-complement therapy; from disease to clinical trial. Molecular immunology, 102. pp. 89-119.

Devaurs, Didier and Papanastasiou, Malvina and Antunes, Dinler A. and Abella, Jayvee R. and Moll, Mark and Ricklin, Daniel and Lambris, John D. and Kavraki, Lydia E.. (2018) Native State of Complement Protein C3d Analysed via Hydrogen Exchange and Conformational Sampling. International journal of computational biology and drug design, 11 (1-2). pp. 90-113.

2017

Yuan, Xiaopeng and Yang, Mingjuan and Chen, Xiang and Zhang, Xuhua and Sukhadia, Shrey and Musolino, Najia and Bao, Huijing and Chen, Tingtao and Xu, Chen and Wang, Qirui and Santoro, Stephen and Ricklin, Daniel and Hu, Jia and Lin, Ruihe and Yang, Wei and Li, Zhijun and Qin, Weijun and Zhao, Aizhi. (2017) Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy. Cancer Immunology, Immunotherapy, 66 (3). pp. 367-378.

Primikyri, Alexandra and Papanastasiou, Malvina and Sarigiannis, Yiannis and Koutsogiannaki, Sophia and Reis, Edimara S. and Tuplano, Joel V. and Resuello, Ranillo R. G. and Nilsson, Bo and Ricklin, Daniel and Lambris, John D.. (2017) Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS. Journal of Chromatography B, 1041-1042. pp. 19-26.

Harder, Markus J. and Kuhn, Nadine and Schrezenmeier, Hubert and Höchsmann, Britta and von Zabern, Inge and Weinstock, Christof and Simmet, Thomas and Ricklin, Daniel and Lambris, John D. and Skerra, Arne and Anliker, Markus and Schmidt, Christoph Q.. (2017) Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation. Blood, 129 (8). pp. 970-980.

Papanastasiou, Malvina and Koutsogiannaki, Sophia and Sarigiannis, Yiannis and Geisbrecht, Brian V. and Ricklin, Daniel and Lambris, John D.. (2017) Structural Implications for the Formation and Function of the Complement Effector Protein iC3b. Journal of immunology (Baltimore, Md. : 1950), 198 (8). pp. 3326-3335.

Devaurs, Didier and Antunes, Dinler A. and Papanastasiou, Malvina and Moll, Mark and Ricklin, Daniel and Lambris, John D. and Kavraki, Lydia E.. (2017) Coarse-Grained Conformational Sampling of Protein Structure Improves the Fit to Experimental Hydrogen-Exchange Data. Frontiers in Molecular Biosciences, 4. p. 13.

Mastellos, Dimitrios C. and Reis, Edimara S. and Ricklin, Daniel and Smith, Richard J. and Lambris, John D.. (2017) Complement C3-Targeted Therapy: Replacing Long-Held Assertions with Evidence-Based Discovery. Trends in Immunology, 38 (6). pp. 383-394.

Xue, Xiaoguang and Wu, Jin and Ricklin, Daniel and Forneris, Federico and Di Crescenzio, Patrizia and Schmidt, Christoph Q. and Granneman, Joke and Sharp, Thomas H. and Lambris, John D. and Gros, Piet. (2017) Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses. Nature Structural and Molecular Biology, 24. pp. 643-651.

Ricklin, Daniel and Barratt-Due, Andreas and Mollnes, Tom Eirik. (2017) Complement in clinical medicine: Clinical trials, case reports and therapy monitoring. Molecular Immunology, 89. pp. 10-21.

Wang, HongBin and Ricklin, Daniel and Lambris, John D.. (2017) Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4. Proceedings of the National Academy of Sciences of the United States of America, 114 (41). pp. 10948-10953.

Hajishengallis, George and Reis, Edimara S. and Mastellos, Dimitrios C. and Ricklin, Daniel and Lambris, John D.. (2017) Novel mechanisms and functions of complement. Nature Immunology, 18 (12). pp. 1288-1298.

Blatt, Adam Z. and Saggu, Gurpanna and Cortes, Claudio and Herbert, Andrew P. and Kavanagh, David and Ricklin, Daniel and Lambris, John D. and Ferreira, Viviana P.. (2017) Factor H C-Terminal Domains Are Critical for Regulation of Platelet/Granulocyte Aggregate Formation. Frontiers in Immunology, 8. p. 1586.

2016

Ricklin, Daniel and Lambris, John D.. (2016) Preformed mediators of defense-Gatekeepers enter the spotlight. Immunological Reviews, 274 (1). pp. 5-8.

Ricklin, Daniel and Reis, Edimara S. and Mastellos, Dimitrios C. and Gros, Piet and Lambris, John D.. (2016) Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense. Immunological Reviews , 274 (1). pp. 33-58.

Schmidt, Christoph Q. and Lambris, John D. and Ricklin, Daniel. (2016) Protection of host cells by complement regulators. Immunological Reviews, 274 (1). pp. 152-171.

2005

Ricklin, Daniel. Surface plasmon resonance applications in drug discovery : with an emphasis on small molecule and low affinity systems. 2005, Doctoral Thesis, University of Basel, Faculty of Science.