Items where Author is "Gagnon, James A."

2020

Ma, Manxiu and Ramirez, Alexandro D. and Wang, Tong and Roberts, Rachel L. and Harmon, Katherine E. and Schoppik, David and Sharma, Avirale and Kuang, Christopher and Goei, Stephanie L. and Gagnon, James A. and Zimmerman, Steve and Tsai, Shengdar Q. and Reyon, Deepak and Joung, J. Keith and Aksay, Emre R. F. and Schier, Alexander F. and Pan, Y. Albert. (2020) Zebrafish dscaml1 Deficiency Impairs Retinal Patterning and Oculomotor Function. Journal of Neuroscience, 40 (1). pp. 143-158.

2019

Wee, Caroline L. and Nikitchenko, Maxim and Wang, Wei-Chun and Luks-Morgan, Sasha J. and Song, Erin and Gagnon, James A. and Randlett, Owen and Bianco, Isaac H. and Lacoste, Alix M. B. and Glushenkova, Elena and Barrios, Joshua P. and Schier, Alexander F. and Kunes, Samuel and Engert, Florian and Douglass, Adam D.. (2019) Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets. Nature neuroscience, 22 (9). pp. 1477-1492.

2018

Montague, Tessa G. and Gagnon, James A. and Schier, Alexander F.. (2018) Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse. Development (Cambridge, England), 145 (24). p. 9.

Raj, Bushra and Gagnon, James A. and Schier, Alexander F.. (2018) Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR-Cas9 barcodes by scGESTALT. Nature protocols, 13 (11). pp. 2685-2713.

Raj, Bushra and Wagner, Daniel E. and McKenna, Aaron and Pandey, Shristi and Klein, Allon M. and Shendure, Jay and Gagnon, James A. and Schier, Alexander F.. (2018) Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain. Nature biotechnology, 36 (5). pp. 442-450.

Gagnon, James A. and Obbad, Kamal and Schier, Alexander F.. (2018) The primary role of zebrafish nanog is in extra-embryonic tissue. Development (Cambridge, England), 145 (1). p. 9.

2017

Rogers, Katherine W. and Lord, Nathan D. and Gagnon, James A. and Pauli, Andrea and Zimmerman, Steven and Aksel, Deniz C. and Reyon, Deepak and Tsai, Shengdar Q. and Joung, J. Keith and Schier, Alexander F.. (2017) Nodal patterning without Lefty inhibitory feedback is functional but fragile. eLife, 6. 6:e28785.

Norris, Megan L. and Pauli, Andrea and Gagnon, James A. and Lord, Nathan D. and Rogers, Katherine W. and Mosimann, Christian and Zon, Leonard I. and Schier, Alexander F.. (2017) Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. eLife, 6. 6:e22626.

2016

McKenna, Aaron and Findlay, Gregory M. and Gagnon, James A. and Horwitz, Marshall S. and Schier, Alexander F. and Shendure, Jay. (2016) Whole-organism lineage tracing by combinatorial and cumulative genome editing. Science (New York, N.Y.), 353 (6298). aaf7907.

2015

Merkle, Florian T. and Neuhausser, Werner M. and Santos, David and Valen, Eivind and Gagnon, James A. and Maas, Kristi and Sandoe, Jackson and Schier, Alexander F. and Eggan, Kevin. (2015) Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus. Cell Reports , 11 (6). pp. 875-883.

Liu, Justin and Merkle, Florian T. and Gandhi, Avni V. and Gagnon, James A. and Woods, Ian G. and Chiu, Cindy N. and Shimogori, Tomomi and Schier, Alexander F. and Prober, David A.. (2015) Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development, 142 (6). pp. 1113-1124.

2014

Gagnon, James A. and Valen, Eivind and Thyme, Summer B. and Huang, Peng and Akhmetova, Laila and Pauli, Andrea and Montague, Tessa G. and Zimmerman, Steven and Richter, Constance and Schier, Alexander F.. (2014) Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. PLoS ONE, 9 (5). e98186.

Pauli, Andrea and Norris, Megan L. and Valen, Eivind and Chew, Guo-Liang and Gagnon, James A. and Zimmerman, Steven and Mitchell, Andrew and Ma, Jiao and Dubrulle, Julien and Reyon, Deepak and Tsai, Shengdar Q. and Joung, J. Keith and Saghatelian, Alan and Schier, Alexander F.. (2014) Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science, 343 (6172). p. 1248636.