Browse by Basel Contributors ID

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Schnoz, Christina and Moser, Sandra and Kratschmar, Denise V. and Odermatt, Alex and Loffing-Cueni, Dominique and Loffing, Johannes. (2021) Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC. Pflügers Archiv : European journal of physiology, 473 (1). pp. 79-93.

Lizák, Beáta and Birk, Julia and Zana, Melinda and Kosztyi, Gergely and Kratschmar, Denise V. and Odermatt, Alex and Zimmermann, Richard and Geiszt, Miklós and Appenzeller-Herzog, Christian and Bánhegyi, Gábor. (2020) Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione. BMC Biology, 18 (1). p. 19.

Schulze, Friederike and Wehner, Josua and Kratschmar, Denise V. and Makshana, Valmir and Meier, Daniel T. and Häuselmann, Stéphanie P. and Dalmas, Elise and Thienel, Constanze and Dror, Erez and Wiedemann, Sophia J. and Traub, Shuyang and Nordmann, Thierry M. and Rachid, Leila and De Baat, Axel and Rohm, Theresa V. and Zhao, Cheng and Odermatt, Alex and Böni-Schnetzler, Marianne and Donath, Marc Y.. (2020) Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes. Scientific Reports, 10 (1). p. 3035.

Gómez, Cristina and Stücheli, Simon and Kratschmar, Denise V. and Bouitbir, Jamal and Odermatt, Alex. (2020) Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples. Metabolites, 10 (7). p. 282.

Strajhar, Petra and Vizeli, Patrick and Patt, Melanie and Dolder, Patrick C. and Kratschmar, Denise V. and Liechti, Matthias E. and Odermatt, Alex. (2019) Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study. Journal of Steroid Biochemistry and Molecular Biology, 186. pp. 212-225.

Trinh, Beckey and Hepprich, Matthias and Betz, Matthias J. and Burkard, Thilo and Cavelti-Weder, Claudia and Seelig, Eleonora and Meienberg, Fabian and Kratschmar, Denise V. and Beuschlein, Felix and Reincke, Martin and Odermatt, Alex and Hall, Michael N. and Donath, Marc Y. and Swierczynska, Marta M.. (2019) Treatment of Primary Aldosteronism with mTORC1 Inhibitors. The Journal of Clinical Endocrinology and Metabolism, 104 (10). pp. 4703-4714.

Akram, Muhammad and Patt, Melanie and Kaserer, Teresa and Temml, Veronika and Waratchareeyakul, Watcharee and Kratschmar, Denise V. and Haupenthal, Joerg and Hartmann, Rolf W. and Odermatt, Alex and Schuster, Daniela. (2019) Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase. Journal of Steroid Biochemistry and Molecular Biology, 192. p. 105358.

Beck, Katharina R. and Kanagaratnam, Sharavan and Kratschmar, Denise V. and Birk, Julia and Yamaguchi, Hideaki and Sailer, Andreas W. and Seuwen, Klaus and Odermatt, Alex. (2019) Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2. The Journal of steroid biochemistry and molecular biology, 190. pp. 19-28.

Sandström, Jenny and Kratschmar, Denise V. and Broyer, Alexandra and Poirot, Olivier and Marbet, Philippe and Chantong, Boonrat and Zufferey, Fanny and Dos Santos, Tania and Boccard, Julien and Chrast, Roman and Odermatt, Alex and Monnet-Tschudi, Florianne. (2019) In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice. Archives of toxicology, 93. pp. 1649-1664.

Beck, Katharina R. and Inderbinen, Silvia G. and Kanagaratnam, Sharavan and Kratschmar, Denise V. and Jetten, Anton M. and Yamaguchi, Hideaki and Odermatt, Alex. (2019) 11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ. Journal of Lipid Research, 60. pp. 1535-1546.

Keppner, Anna and Maric, Darko and Sergi, Chloé and Ansermet, Camille and De Bellis, Damien and Kratschmar, Denise V. and Canonica, Jérémie and Klusonova, Petra and Fenton, Robert A. and Odermatt, Alex and Crambert, Gilles and Hoogewijs, David and Hummler, Edith. (2019) Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion. Scientific Reports, 9 (1). p. 19540.

Thompson, George R. and Beck, Katharina R. and Patt, Melanie and Kratschmar, Denise V. and Odermatt, Alex. (2019) Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2. Journal of the Endocrine Society, 3 (7). pp. 1361-1366.

Engeli, Roger T. and Fürstenberger, Cornelia and Kratschmar, Denise V. and Odermatt, Alex. (2018) Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis. Heliyon, 4 (2). e00527.

Marbet, Philippe and Klusonova, Petra and Birk, Julia and Kratschmar, Denise V. and Odermatt, Alex. (2018) Absence of hexose-6-phosphate dehydrogenase results in reduced overall glucose consumption but does not prevent 11β-hydroxysteroid dehydrogenase-1-dependent glucocorticoid activation. The FEBS journal, 285 (21). pp. 3993-4004.

Tsachaki, Maria and Meyer, Arne and Weger, Benjamin and Kratschmar, Denise V. and Tokarz, Janina and Adamski, Jerzy and Belting, Heinz-Georg and Affolter, Markus and Dickmeis, Thomas and Odermatt, Alex. (2017) Absence of 11-keto reduction of cortisone and 11-ketotestosterone in the model organism zebrafish. Journal of Endocrinology, 232 (2). pp. 323-335.

Araya, Selene and Kratschmar, Denise V. and Tsachaki, Maria and Stücheli, Simon and Beck, Katharina R. and Odermatt, Alex. (2017) DHRS7 (SDR34C1) - A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone? Journal of Steroid Biochemistry and Molecular Biology, 27. pp. 288-295.

Strajhar, Petra and Tonoli, David and Jeanneret, Fabienne and Imhof, Raphaella M. and Malagnino, Vanessa and Patt, Melanie and Kratschmar, Denise V. and Boccard, Julien and Rudaz, Serge and Odermatt, Alex. (2017) Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids. Toxicology, 381. pp. 51-63.

Boudon, Stéphanie M. and Vuorinen, Anna and Geotti-Bianchini, Piero and Wandeler, Eliane and Kratschmar, Denise V. and Heidl, Marc and Campiche, Remo and Jackson, Eileen and Odermatt, Alex. (2017) Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UV. PLoS ONE, 12 (2). e0171079.

Bonifacio, Annalisa and Sanvee, Gerda M. and Brecht, Karin and Kratschmar, Denise V. and Odermatt, Alex and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91 (5). pp. 2223-2234.

Knöpfel, Thomas and Pastor-Arroyo, Eva M. and Schnitzbauer, Udo and Kratschmar, Denise V. and Odermatt, Alex and Pellegrini, Giovanni and Hernando, Nati and Wagner, Carsten A.. (2017) The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction. Scientific reports, 7 (1). p. 11018.

Alesutan, Ioana and Voelkl, Jakob and Feger, Martina and Kratschmar, Denise V. and Castor, Tatsiana and Mia, Sobuj and Sacherer, Michael and Viereck, Robert and Borst, Oliver and Leibrock, Christina and Gawaz, Meinrad and Kuro-O, Makoto and Pilz, Stefan and Tomaschitz, Andreas and Odermatt, Alex and Pieske, Burkert and Wagner, Carsten A. and Lang, Florian. (2017) Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells. Scientific Reports, 7 (1). p. 2059.

Strajhar, Petra and Schmid, Y. and Liakoni, E. and Dolder, P. C. and Rentsch, K. M. and Kratschmar, Denise V. and Odermatt, Alex and Liechti, Matthias E.. (2016) Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects. Journal of Neuroendocrinology, 28 (3). p. 12374.

Seibert, Julia and Hysek, Cédric M. and Penno, Carlos A. and Schmid, Yasmin and Kratschmar, Denise V. and Liechti, Matthias E. and Odermatt, Alex. (2014) Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects. Neuroendocrinology, 100 (1). pp. 17-25.

Chantong, Boonrat and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex. (2014) Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive G i -proteins in murine BV-2 microglia cells. Journal of neuroinflammation, Vol. 11, H. 1. p. 190.

Chantong, Boonrat and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex. (2014) Dibutyltin promotes oxidative stress and increases inflammatory mediators in BV-2 microglia cells. Toxicology letters, Vol. 230, H. 2. pp. 177-187.

Felser, Andrea and Lindinger, Peter W. and Schnell, Dominik and Kratschmar, Denise V. and Odermatt, Alex and Mies, Suzette and Jenö, Paul and Krähenbühl, Stephan. (2014) Hepatocellular toxicity of benzbromarone : Effects on mitochondrial function and structure. Toxicology, Vol. 324. pp. 136-146.

Copple, Ian M. and Shelton, Luke M. and Walsh, Joanne and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex and Goldring, Christopher E. and Dinkova-Kostova, Albena T. and Honda, Tadashi and Park, B. Kevin. (2014) Chemical tuning enhances both potency toward nrf2 and in vitro therapeutic index of triterpenoids. Review of Economic Dynamics, 140 (2). pp. 462-469.

Hofer, Sandra and Kratschmar, Denise V. and Schernthanner, Brigitte and Vuorinen, Anna and Schuster, Daniela and Odermatt, Alex and Easmon, Johnny. (2013) Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11β-hydroxysteroid dehydrogenase 1 inhibitors. Bioorganic and Medicinal Chemistry Letters, 23 (19). pp. 5397-5400.

Kratschmar, Denise V. and Calabrese, Diego and Walsh, Jo and Lister, Adam and Birk, Julia and Appenzeller-Herzog, Christian and Moulin, Pierre and Goldring, Chris E. and Odermatt, Alex. (2012) Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells. PLoS ONE, 7 (5). e36774.

Chantong, Boonrat and Kratschmar, Denise V. and Nashev, Lyubomir G. and Balazs, Zoltan and Odermatt, Alex. (2012) Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells. Journal of neuroinflammation, Vol. 9. p. 260.

Fürstenberger, Cornelia and Vuorinen, Anna and Da Cunha, Thierry and Kratschmar, Denise V. and Saugy, Martial and Schuster, Daniela and Odermatt, Alex. (2012) The anabolic androgenic steroid fluoxymesterone inhibits 11β-hydroxysteroid dehydrogenase 2-dependent glucocorticoid inactivation. Toxicological sciences, Vol. 126, H. 2. pp. 353-361.

Odermatt, Alex and Kratschmar, Denise V.. (2012) Tissue-specific modulation of mineralocorticoid receptor function by 11β-hydroxysteroid dehydrogenases : an overview. Molecular and cellular endocrinology, Vol. 350, H. 2. pp. 168-186.

Kratschmar, Denise. Metabolism and action of glucocorticoids and interference with the antioxidant redox pathway. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Kratschmar, Denise V. and Vuorinen, Anna and Da Cunha, Thierry and Wolber, Gerhard and Classen-Houben, Dirk and Doblhoff, Otto and Schuster, Daniela and Odermatt, Alex. (2011) Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11?-hydroxysteroid dehydrogenase type 2. The journal of steroid biochemistry and molecular biology, Vol. 125, H. 1-2. pp. 129-142.

Gaware, Rawindra and Khunt, Rupesh and Czollner, Laszlo and Stanetty, Christian and Da Cunha, Thierry and Kratschmar, Denise V. and Odermatt, Alex and Kosma, Paul and Jordis, Ulrich and Classen-Houben, Dirk. (2011) Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors. Bioorganic & medicinal chemistry, Vol. 19, H. 6. pp. 1866-1880.

Rollinger, Judith M. and Kratschmar, Denise V. and Schuster, Daniela and Pfisterer, Petra H. and Gumy, Christel and Aubry, Evelyne M. and Brandstötter, Sarah and Stuppner, Hermann and Wolber, Gerhard and Odermatt, Alex. (2010) 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches. Bioorganic & medicinal chemistry, Vol. 18, H. 4. pp. 1507-1515.

Gumy, C. and Chandsawangbhuwana, C. and Dzyakanchuk, A. A. and Kratschmar, D. V. and Baker, M. E. and Odermatt, A.. (2008) Dibutyltin disrupts glucocorticoid receptor function and impairs glucocorticoid-induced suppression of cytokine production. PLoS ONE, Vol. 3, H. 10 , e3545.