Real-time mass sensing by nanomechanical resonators in fluid

Ghatkesar, Murali K. and Barwich, V. and Braun, T. and Bredekamp, A. H. and Drechsler, U. and Despont, M. and Lang, H. P. and Hegner, M. and Gerber, C.. (2004) Real-time mass sensing by nanomechanical resonators in fluid. In: Proceedings of the IEEE Sensors 2004, 2. Piscataway, New Jersey, pp. 1060-1063.

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Official URL: https://edoc.unibas.ch/83889/

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We have developed a sensitive method for real-time mass sensing in a fluid using a microfabricated array of nanomechanical cantilevers actuated at their resonance frequencies. The sensor platform consists of a streptavidin layer immobilised onto gold-coated cantilevers and interacts with biotin-labeled latex beads. The addition of mass involved with this process decreased the resonance frequency. By monitoring frequency spectra of higher harmonies we measured a mass sensitivity of 3.3 Hz/pg. Our data demonstrate that the sensitivity can be increased by operating the cantilever at higher harmonics.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Structural Biology & Biophysics > Structural Biology (Braun)
UniBasel Contributors:Braun, Thomas
Item Type:Conference or Workshop Item, refereed
Conference or workshop item Subtype:Conference Paper
Note:Publication type according to Uni Basel Research Database: Conference paper
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Last Modified:14 Jul 2021 10:25
Deposited On:14 Jul 2021 10:25

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