Ghatkesar, Murali K. and Barwich, V. and Braun, T. and Bredekamp, A. H. and Drechsler, U. and Despont, M. and Lang, H. P. and Hegner, M. and Gerber, C.. (2004) Real-time mass sensing by nanomechanical resonators in fluid. In: Proceedings of the IEEE Sensors 2004, 2. Piscataway, New Jersey, pp. 1060-1063.
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Official URL: https://edoc.unibas.ch/83889/
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Abstract
We have developed a sensitive method for real-time mass sensing in a fluid using a microfabricated array of nanomechanical cantilevers actuated at their resonance frequencies. The sensor platform consists of a streptavidin layer immobilised onto gold-coated cantilevers and interacts with biotin-labeled latex beads. The addition of mass involved with this process decreased the resonance frequency. By monitoring frequency spectra of higher harmonies we measured a mass sensitivity of 3.3 Hz/pg. Our data demonstrate that the sensitivity can be increased by operating the cantilever at higher harmonics.
Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Structural Biology & Biophysics > Structural Biology (Braun) |
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UniBasel Contributors: | Braun, Thomas |
Item Type: | Conference or Workshop Item, refereed |
Conference or workshop item Subtype: | Conference Paper |
Publisher: | IEEE |
ISBN: | 978-0-7803-8692-1 |
Note: | Publication type according to Uni Basel Research Database: Conference paper |
Identification Number: | |
Last Modified: | 14 Jul 2021 10:25 |
Deposited On: | 14 Jul 2021 10:25 |
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