Items where Author is "Flesch, Daniel"

2017

Flesch, Daniel and Cheung, Sun-Yee and Schmidt, Jurema and Gabler, Matthias and Heitel, Pascal and Kramer, Jan and Kaiser, Astrid and Hartmann, Markus and Lindner, Mara and Lüddens-Dämgen, Kerstin and Heering, Jan and Lamers, Christina and Lüddens, Hartmut and Wurglics, Mario and Proschak, Ewgenij and Schubert-Zsilavecz, Manfred and Merk, Daniel. (2017) Nonacidic Farnesoid X Receptor Modulators. Journal of Medicinal Chemistry, 60 (16). pp. 7199-7205.

2016

Lamers, Christina and Merk, Daniel and Gabler, Matthias and Flesch, Daniel and Kaiser, Astrid and Schubert-Zsilavecz, Manfred. (2016) SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound. Future medicinal chemistry, 8 (2). pp. 133-148.

2015

Merk, Daniel and Lamers, Christina and Weber, Julia and Flesch, Daniel and Gabler, Matthias and Proschak, Ewgenij and Schubert-Zsilavecz, Manfred. (2015) Anthranilic acid derivatives as nuclear receptor modulators--development of novel PPAR selective and dual PPAR/FXR ligands. Bioorganic & medicinal chemistry, 23 (3). pp. 499-514.

Flesch, Daniel and Ness, Julia and Lamers, Christina and Dehm, Friederike and Popella, Sven and Steri, Ramona and Ogorek, Isabella and Hieke, Martina and Dannhardt, Gerd and Werz, Oliver and Weggen, Sascha and Schubert-Zsilavecz, Manfred. (2015) SAR-studies of γ-secretase modulators with PPARγ-agonistic and 5-lipoxygenase-inhibitory activity for Alzheimer's disease. Bioorganic and Medicinal Chemistry Letters, 25 (4). pp. 841-846.

2014

Merk, Daniel and Gabler, Matthias and Gomez, Roberto Carrasco and Flesch, Daniel and Hanke, Thomas and Kaiser, Astrid and Lamers, Christina and Werz, Oliver and Schneider, Gisbert and Schubert-Zsilavecz, Manfred. (2014) Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR). Bioorganic & medicinal chemistry, 22 (8). pp. 2447-2460.

2013

Flesch, Daniel and Merk, Daniel and Lamers, Christina and Schubert-Zsilavecz, Manfred. (2013) Novel prostaglandin receptor modulators - part II: EP receptor modulators; a patent review (2002 - 2012). Expert opinion on therapeutic patents, 23 (2). pp. 233-267.

Lamers, Christina and Flesch, Daniel and Schubert-Zsilavecz, Manfred and Merk, Daniel. (2013) Novel prostaglandin receptor modulators: a patent review (2002 - 2012) - part I: non-EP receptor modulators. Expert opinion on therapeutic patents, 23 (1). pp. 47-77.