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Brecht, Karin and Kirchhofer, Carla and Bouitbir, Jamal and Trapani, Francesca and Keiser, Jennifer and Krähenbühl, Stephan. (2019) Exogenous iron increases fasciocidal activity and hepatocellular toxicity of the synthetic endoperoxides OZ78 and MT04. International Journal of Molecular Sciences, 20 (19). p. 4880.


Bonifacio, Annalisa and Sanvee, Gerda M. and Brecht, Karin and Kratschmar, Denise V. and Odermatt, Alex and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91 (5). pp. 2223-2234.

Brecht, Karin and Riebel, Virginie and Couttet, Philippe and Paech, Franziska and Wolf, Armin and Chibout, Salah-Dine and Pognan, Francois and Krähenbühl, Stephan and Uteng, Marianne. (2017) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicology in Vitro, 40. pp. 55-65.


Maseneni, Swarna and Donzelli, Massimiliano and Brecht, Karin and Krähenbühl, Stephan. (2013) Toxicity of thienopyridines on human neutrophil granulocytes and lymphocytes. Toxicology, 308. pp. 11-19.

Zahno, Anja and Bouitbir, Jamal and Maseneni, Swarma and Lindinger, Peter W. and Brecht, Karin and Krähenbühl, Stephan. (2013) Hepatocellular toxicity of clopidogrel: Mechanisms and risk factors. Free radical biology and medicine, 65. pp. 208-216.


Maseneni, Swarna and Donzelli, Massimiliano and Taegtmeyer, A. B. and Brecht, Karin and Krähenbühl, Stephan. (2012) Toxicity of clopidogrel and ticlopidine on human myeloid progenitor cells: importance of metabolites. Toxicology, 299 (2-3). pp. 139-145.


Zahno, Anja and Brecht, Karin and Morand, Réjane and Maseneni, Swarna and Török, Michael and Lindinger, Peter W. and Krähenbühl, Stephan. (2011) The role of CYP3A4 in amiodarone-associated toxicity on HepG2 cells. Biochemical pharmacology, Vol. 81, Issue 3. pp. 432-441.

Mullen, Peter J. and Zahno, Anja and Lindinger, Peter and Maseneni, Swarma and Felser, Andrea and Krähenbühl, Stephan and Brecht, Karin. (2011) Susceptibility to simvastatin-induced toxicity is partly determined by mitochondrial respiration and phosphorylation state of Akt. Biochimica et biophysica acta, Vol. 1813, H. 12. pp. 2079-2087.


Mullen, Peter James and Lüscher, Barbara and Scharnagl, Hubert and Krähenbühl, Stephan and Brecht, Karin. (2010) Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy. Biochemical pharmacology, 79 (8). pp. 1200-1209.

Zahno, Anja and Brecht, Karin and Bodmer, Michael and Bur, Daniel and Tsakiris, Dimitrios A. and Krähenbühl, Stephan. (2010) Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. British journal of pharmacology, 161 (2). pp. 393-404.


Waldhauser, Katri M. and Brecht, Karin and Hebeisen, S. and Ha, H. R. and Konrad, D. and Bur, Daniel and Krähenbühl, Stephan. (2008) Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues. British journal of pharmacology, 155 (4). pp. 585-595.


Waldhauser, Katri and Török, Michael and Ha, Huy-Riem and Thomet, Urs and Konrad, Daniel and Brecht, Karin and Follath, Ferenc and Krahenbühl, Stephan. (2006) Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives. Journal of pharmacology and experimental therapeutics, 319 (3). pp. 1413-1423.

Kaufmann, Priska and Török, Michael and Zahno, Anja and Waldhauser, Katri and Brecht, Karin and Krähenbühl, Stephan. (2006) Toxicity of statins on rat skeletal muscle mitochondria. Cellular and Molecular Life Sciences, 63 (19-20). pp. 2415-2425.


Rudin, Markus and McSheehy, Paul M. J. and Allegrini, Peter R. and Rausch, Martin and Baumann, Diana and Becquet, Mike and Brecht, Karin and Brueggen, Josef and Ferretti, Stephane and Schaeffer, Fabienne and Schnell, Christian and Wood, Jeanette. (2005) PTK787/ZK222584, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor, reduces uptake of the contrast agent GdDOTA by murine orthotopic B16/BL6 melanoma tumours and inhibits their growth in vivo. NMR in Biomedicine, 18 (5). pp. 308-21..

Brecht , Karin and Simonen, Marjo and Kamke, M. and Heim, Jutta. (2005) Hematopoietic transcription factor GATA-2 promotes expression of alpha globin and cell death in FL5.12 cells. Apoptosis, 10 (5). pp. 1063-1078.

Brecht, Karin and Simonen, Marjo and Heim, Jutta. (2005) Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12. Apoptosis, 10 (5). pp. 1043-1062.


Brachat, Arndt and Pierrat, Benoit and Xynos, Alexandros and Brecht, Karin and Simonen, Marjo and Brüngger, Adrian and Heim, Jutta. (2002) A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis. Oncogene, 21 (54). pp. 8361-8371.