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Witzigmann, Dominik and Grossen, Philip and Quintavalle, Cristina and Lanzafame, Manuela and Schenk, Susanne H. and Tran, Xue-Ting and Englinger, Bernhard and Hauswirth, Patrick and Grünig, David and van Schoonhoven, Sushilla and Krähenbühl, Stephan and Terracciano, Luigi M. and Berger, Walter and Piscuoglio, Salvatore and Quagliata, Luca and Rommelaere, Jean and Nüesch, Jürg P. F. and Huwyler, Jörg. (2021) Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma. Journal of Controlled Release, 334. pp. 138-152.

Chander, Nisha and Morstein, Johannes and Bolten, Jan S. and Shemet, Andrej and Cullis, Pieter R. and Trauner, Dirk and Witzigmann, Dominik. (2021) Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release. Small, 17 (21). e2008198.

Einfalt, Tomaz and Garni, Martina and Witzigmann, Dominik and Sieber, Sandro and Baltisberger, Niklaus and Huwyler, Jörg and Meier, Wolfgang and Palivan, Cornelia. (2020) Bioinspired Molecular Factories with Architecture and In Vivo Functionalities as Cell Mimics. Advanced Science, 7 (4). p. 1901923.

Sedighi, Mahsa and Rahimi, Fereshteh and Shahbazi, Mohammad-Ali and Rezayan, Ali Hossein and Kettiger, Helene and Einfalt, Tomaz and Huwyler, Jörg and Witzigmann, Dominik. (2020) Controlled Tyrosine Kinase Inhibitor Delivery to Liver Cancer Cells by Gate-Capped Mesoporous Silica Nanoparticles. ACS Applied Bio Materials, 3 (1). pp. 239-251.

Liu, Juan and Craciun, Ioana and Belluati, Andrea and Wu, Dalin and Sieber, Sandro and Einfalt, Tomaz and Witzigmann, Dominik and Chami, Mohamed and Huwyler, Jörg and Palivan, Cornelia G.. (2020) DNA-directed arrangement of soft synthetic compartments and their behavior in vitro and in vivo. Nanoscale, 12 (17). pp. 9786-9799.

Buck, Jonas and Mueller, Dennis and Mettal, Ute and Ackermann, Miriam and Grisch-Chan, Hiu Man and Thöny, Beat and Zumbuehl, Andreas and Huwyler, Jörg and Witzigmann, Dominik. (2020) Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids. ACS Omega, 5 (38). pp. 24724-24732.

Sedighi, Mahsa and Sieber, Sandro and Rahimi, Fereshteh and Shahbazi, Mohammad-Ali and Rezayan, Ali Hossein and Huwyler, Jörg and Witzigmann, Dominik. (2019) Rapid optimization of liposome characteristics using a combined microfluidics and design-of-experiment approach. Drug delivery and translational research, 9 (1). pp. 404-413.

Sieber, Sandro and Grossen, Philip and Uhl, Philipp and Detampel, Pascal and Mier, Walter and Witzigmann, Dominik and Huwyler, Jörg. (2019) Zebrafish as a predictive screening model to assess macrophage clearance of liposomes in vivo. Nanomedicine: nanotechnology, biology and medicine, 17. pp. 82-93.

Sieber, Sandro and Grossen, Philip and Bussmann, Jeroen and Campbell, Frederick and Kros, Alexander and Witzigmann, Dominik and Huwyler, Jörg. (2019) Zebrafish as a preclinical in vivo screening model for nanomedicines. Advanced drug delivery reviews (151-152). pp. 152-168.

Buck, Jonas and Grossen, Philip and Cullis, Pieter R. and Huwyler, Jörg and Witzigmann, Dominik. (2019) Lipid-Based DNA Therapeutics - Hallmarks of Non-Viral Gene Delivery. ACS Nano, 13 (4). pp. 3754-3782.

Witzigmann, Dominik and Uhl, Philipp and Sieber, Sandro and Kaufman, Christina and Einfalt, Tomaz and Schöneweis, Katrin and Grossen, Philip and Buck, Jonas and Ni, Yi and Schenk, Susanne H. and Hussner, Janine and Meyer Zu Schwabedissen, Henriette E. and Québatte, Gabriela and Mier, Walter and Urban, Stephan and Huwyler, Jörg. (2019) Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide. eLife, 8. e42276.

Bleher, Stefan and Buck, Jonas and Muhl, Christian and Sieber, Sandro and Barnert, Sabine and Witzigmann, Dominik and Huwyler, Jörg and Braz, Matthias and Süss, Regine. (2019) Poly(Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes. Small, 15 (50). p. 1904716.

Einfalt, Tomaz and Witzigmann, Dominik and Edlinger, Christoph and Sieber, Sandro and Goers, Roland and Najer, Adrian and Spulber, Mariana and Onaca-Fischer, Ozana and Huwyler, Jörg and Palivan, Cornelia G.. (2018) Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment. Nature Communications, 9. p. 1127.

Sedighi, Mahsa and Rahimi, Fereshteh and Rezayan, Ali Hossein and Shahbazi, Mohammad-Ali and Witzigmann, Dominik and Huwyler, Jörg. (2018) Combined cerium oxide nanocapping and layer-by-layer coating of porous silicon containers for controlled drug release. Journal of Materials Science, 53. pp. 14975-14988.

Grossen, Philip and Witzigmann, Dominik and Sieber, Sandro and Huwyler, Jörg. (2017) PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application. Journal of Controlled Release, 260. pp. 46-60.

Kiene, Klara and Schenk, Susanne H. and Porta, Fabiola and Ernst, Alexandra and Witzigmann, Dominik and Grossen, Philip and Huwyler, Jörg. (2017) PDMS-b-PMOXA polymersomes for hepatocyte targeting and assessment of toxicity. European Journal of Pharmaceutics and Biopharmaceutics, 119. pp. 322-332.

Uhl, Philipp and Pantze, Silvia and Storck, Philip and Parmentier, Johannes and Witzigmann, Dominik and Hofhaus, Götz and Huwyler, Jörg and Mier, Walter and Fricker, Gert. (2017) Oral delivery of vancomycin by tetraether lipid liposomes. European Journal of Pharmaceutical Sciences, 108. pp. 111-118.

Gliesche, Daniel G. and Hussner, Janine and Witzigmann, Dominik and Porta, Fabiola and Glatter, Timo and Schmidt, Alexander and Huwyler, Jörg and Meyer Zu Schwabedissen, Henriette E.. (2016) Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries. Molecular Pharmaceutics, 13 (7). pp. 2290-2300.

Witzigmann, Dominik and Quagliata, Luca and Schenk, Susanne H. and Quintavalle, Cristina and Terracciano, Luigi M. and Huwyler, Jörg. (2016) Variable asialoglycoprotein-receptor 1 expression in liver disease: Implications for therapeutic intervention. Hepatology research , 46 (7). pp. 686-696.

Grossen, Philip and Québatte, Gabriela and Witzigmann, Dominik and Prescianotto-Baschong, Cristina and Dieu, Le-Ha and Huwyler, Jörg. (2016) Functionalized Solid-Sphere PEG-b-PCL Nanoparticles to Target Brain Capillary Endothelial Cells In Vitro. Journal of Nanomaterials, 2016. p. 7818501.

Witzigmann, Dominik and Detampel, Pascal and Porta, Fabiola and Huwyler, Jörg. (2016) Isolation of Multiantennary N-Glycans from Glycoproteins for Hepatocyte Specific Targeting via the Asialoglycoprotein Receptor. RSC Advances, 6. pp. 97636-97640.

Witzigmann, Dominik and Wu, Dalin and Schenk, Susanne H. and Balasubramanian, Vimalkumar and Meier, Wolfgang P. and Huwyler, Jörg . (2015) Biocompatible Polymer–Peptide Hybrid-Based DNA Nanoparticles for Gene Delivery. ACS Applied Materials and Interfaces, 7 (19). pp. 10446-10456.

Witzigmann, Dominik and Sieber, Sandro and Porta, Fabiola and Grossen, Philip and Bieri, Andrej and Strelnikova, Natalja and Pfohl, Thomas and Prescianotto-Baschong, Cristina and Huwyler, Jörg. (2015) Formation of lipid and polymer based gold nanohybrids using a nanoreactor approach. RSC Advances, 5 (91). pp. 74320-74328.

Detampel, Pascal and Witzigmann, Dominik and Krähenbühl, Stephan and Huwyler, Jörg. (2014) Hepatocyte targeting using pegylated asialofetuin-conjugated liposomes. Journal of drug targeting, Vol. 22, No. 3. pp. 232-241.

Book Section

Witzigmann, Dominik and Camblin, Marine and Huwyler, Jürg and Balasubramaniana, Vimalkumar. (2015) Nanomaterials: Therapeutic Applications. In: Encyclopedia of Biomedical Polymers and Polymer Biomaterials. New York, pp. 5364-5378.

Thesis

Witzigmann, Dominik. Hepatocyte-specific drug delivery using active targeted nanomedicines - evaluation of targeting strategies in vitro and in vivo. 2016, Doctoral Thesis, University of Basel, Faculty of Science.