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Items where contributor is "Duthaler, Urs"

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2022

Becker, Anna M. and Holze, Friederike and Grandinetti, Tanja and Klaiber, Aaron and Toedtli, Vanja E. and Kolaczynska, Karolina E. and Duthaler, Urs and Varghese, Nimmy and Eckert, Anne and Grünblatt, Edna and Liechti, Matthias E.. (2022) Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects. Clinical Pharmacology & Therapeutics, 111 (4). pp. 886-895.

2021

Duthaler, Urs and Weber, Michael and Hofer, Lorenz and Chaccour, Carlos and Maia, Marta and Müller, Pie and Krähenbühl, Stephan and Hammann, Felix. (2021) The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes. PLoS Pathogens, 17 (3). e1009382.

Bachmann, Fabio and Duthaler, Urs and Meyer Zu Schwabedissen, Henriette E. and Puchkov, Maxim and Huwyler, Jörg and Haschke, Manuel and Krähenbühl, Stephan. (2021) Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2. Clinical Pharmacology and Therapeutics, 109 (6). pp. 1505-1516.

Blaser, Lea S. and Duthaler, Urs and Bouitbir, Jamal and Leuppi-Taegtmeyer, Anne B. and Liakoni, Evangelia and Dolf, Reto and Mayr, Michael and Drewe, Jürgen and Krähenbühl, Stephan and Haschke, Manuel. (2021) Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study. Frontiers in Pharmacology, 12. p. 620635.

2020

Roos, Noëmi Johanna and Duthaler, Urs and Bouitbir, Jamal and Krähenbühl, Stephan. (2020) The uricosuric benzbromarone disturbs the mitochondrial redox homeostasis and activates the NRF2 signaling pathway in HepG2 cells. Free radical biology and medicine, 152. pp. 216-226.

Panajatovic, Miljenko Valentin and Singh, François and Roos, Noëmi Johanna and Duthaler, Urs and Handschin, Christoph and Krähenbühl, Stephan and Bouitbir, Jamal. (2020) PGC-1α plays a pivotal role in simvastatin-induced exercise impairment in mice. Acta physiologica (Oxford, England), 228 (4). e13402.

2019

Malagnino, Vanessa and Duthaler, Urs and Seibert, Isabell and Krähenbühl, Stephan and Meyer Zu Schwabedissen, Henriette E.. (2019) OATP1B3-1B7 (LST-3TM12) Is a Drug Transporter That Affects Endoplasmic Reticulum Access and the Metabolism of Ezetimibe. Molecular Pharmacology, 96 (2). pp. 128-137.

Singh, François and Zoll, Joffrey and Duthaler, Urs and Charles, Anne-Laure and Panajatovic, Miljenko V. and Laverny, Gilles and McWilliams, Thomas G. and Metzger, Daniel and Geny, Bernard and Krähenbühl, Stephan and Bouitbir, Jamal. (2019) PGC-1β modulates statin-associated myotoxicity in mice. Archives of Toxicology, 93 (2). pp. 487-504.

2018

Grünig, David and Felser, Andrea and Duthaler, Urs and Bouitbir, Jamal and Krähenbühl, Stephan. (2018) Effect of the Catechol-O-Methyltransferase Inhibitors Tolcapone and Entacapone on Fatty Acid Metabolism in HepaRG Cells. Toxicological sciences, 164 (2). pp. 477-488.

Duthaler, Urs and Suenderhauf, Claudia and Karlsson, Mats O. and Hussner, Janine and Meyer Zu Schwabedissen, Henriette and Krähenbühl, Stephan and Hammann, Felix. (2018) Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers. British journal of clinical pharmacology, 85 (3). pp. 626-633.

Paech, Franziska and Abegg, Vanessa F. and Duthaler, Urs and Terracciano, Luigi and Bouitbir, Jamal and Krähenbühl, Stephan. (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology, 409. pp. 13-23.

2017

Duthaler, Urs and Berger, Benjamin and Erb, Stefan and Battegay, Manuel and Letang, Emilio and Gaugler, Stefan and Krähenbühl, Stephan and Haschke, Manuel. (2017) Automated high throughput analysis of antiretroviral drugs in dried blood spots. Journal of Mass Spectrometry, 52 (8). pp. 534-542.

Erb, S. and Letang, E. and Glass, T. R. and Natamatungiro, A. and Mnzava, D. and Mapesi, H. and Haschke, M. and Duthaler, U. and Berger, B. and Muri, L. and Bader, J. and Marzolini, C. and Elzi, L. and Klimkait, T. and Langewitz, W. and Battegay, M. and Kilombero Ulanga Antiretroviral Cohort study group, . (2017) Health care provider communication training in rural Tanzania empowers HIV-infected patients on antiretroviral therapy to discuss adherence problems. HIV medicine, 18 (9). pp. 623-634.

2016

Meister, Isabel and Leonidova, Anna and Kovač, Jana and Duthaler, Urs and Keiser, Jennifer and Huwyler, Jörg. (2016) Development and validation of an enantioselective LC-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in human plasma, blood and dried blood spots. Journal of pharmaceutical and biomedical analysis, 118. pp. 81-88.

Vanobberghen, Fiona and Penny, Melissa A. and Duthaler, Urs and Odermatt, Peter and Sayasone, Somphou and Keiser, Jennifer and Tarning, Joel. (2016) Population pharmacokinetic modeling of tribendimidine metabolites in opisthorchis viverrini-Infected adults. Antimicrobial agents and chemotherapy, 60 (10). pp. 5695-5704.

Sayasone, Somphou and Odermatt, Peter and Vonghachack, Youthanavanh and Xayavong, Syda and Senggnam, Kanpaseuth and Duthaler, Urs and Akkhavong, Kongsap and Hattendorf, Jan and Keiser, Jennifer. (2016) Efficacy and safety of tribendimidine against Opisthorchis viverrini : two randomised, parallel-group, single-blind, dose-ranging, phase 2 trials. Lancet Infectious Diseases, 16 (10). pp. 1145-1453.

Duthaler, Urs and Sayasone, Somphou and Vanobbergen, Fiona and Penny, Melissa A. and Odermatt, Peter and Huwyler, Jörg and Keiser, Jennifer. (2016) Single ascending dose pharmacokinetic study of tribendimidine in Opisthorchis viverrini-infected patients. Antimicrobial agents and chemotherapy, 60 (10). pp. 5705-5715.

Bouitbir, Jamal and Haegler, Patrizia and Singh, François and Joerin, Lorenz and Felser, Andrea and Duthaler, Urs and Krähenbühl, Stephan. (2016) Impaired Exercise Performance and Skeletal Muscle Mitochondrial Function in Rats with Secondary Carnitine Deficiency. Frontiers in Physiology, 7. p. 345.

2015

Duthaler, Urs and Keiser, Jennifer and Huwyler, Jörg. (2015) LC-MS/MS method for the determination of two metabolites of tribendimidine, deacylated amidantel and its acetylated metabolite in plasma, blood and dried blood spots. Journal of Pharmaceutical and Biomedical Analysis, 105. pp. 163-173.

2013

Ingram, Katrin and Duthaler, Urs and Vargas, Mireille and Ellis, William and Keiser, Jennifer. (2013) Disposition of mefloquine and enpiroline is highly influenced by a chronic Schistosoma mansoni infection. Antimicrobial agents and chemotherapy, Vol. 57, H. 9. pp. 4506-4511.

Meister, Isabel and Duthaler, Urs and Huwyler, Jörg and Rinaldi, Laura and Bosco, Antonio and Cringoli, Giuseppe and Keiser, Jennifer. (2013) Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with Fasciola hepatica in sheep. Veterinary parasitology, Vol. 198, H. 1-2. pp. 102-110.

2012

Duthaler, U. and Huwyler, J. and Rinaldi, L. and Cringoli, G. and Keiser, J.. (2012) Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with Fasciola hepatica. Veterinary parasitology, Vol. 186, H. 3-4. pp. 270-280.

Saric, J. and Want, E. J. and Duthaler, U. and Lewis, M. and Keiser, J. and Schockcor, J. P. and Ross, G. A. and Nicholson, J. K. and Holmes, E. and Tavares, M. F.. (2012) Systematic evaluation of extraction methods for multi-platform based metabotyping : application to the Fasciola hepatica metabolome. Analytical chemistry, Vol. 84, H. 16. pp. 6963-6972.

2011

Duthaler, Urs and Keiser, Jennifer and Huwyler, Jörg. (2011) Development and validation of a liquid chromatography and ion spray tandem mass spectrometry method for the quantification of artesunate, artemether, and their major metabolites dihydroartemisinin and dihydroartemisininglucuronide in sheep plasma. Journal of Mass Spectrometry, 46 (2). pp. 172-181.

2010

Keiser, Jennifer and Veneziano, Vincenzo and Rinaldi, Laura and Mezzino, Laura and Duthaler, Urs and Cringoli, Giuseppe. (2010) Anthelmintic activity of artesunate against Fasciola hepatica in naturally infected sheep. Research in Veterinary Science, Vol. 88, H. 1. pp. 107-110.

Duthaler, U. and Smith, T. A. and Keiser, J.. (2010) In vivo and in vitro sensitivity of Fasciola hepatica to combinations of triclabendazole and artesunate, artemether or OZ78. Antimicrobial agents and chemotherapy : AAC, Vol. 54, H. 11. pp. 4596-4604.

Duthaler, U. and Rinaldi, L. and Maurelli, M. P. and Vargas, M. and Utzinger, J. and Cringoli, G. and Keiser, J.. (2010) Fasciola hepatica: comparison of the sedimentation and FLOTAC techniques for the detection and quantification of faecal egg counts in rats. Experimental parasitology : EP, Vol. 126, H. 2. pp. 161-166.