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Long-term exposure to traffic-related air pollution and diabetes: a systematic review and meta-analysis

Kutlar Joss, M. and Boogaard, H. and Samoli, E. and Patton, A. P. and Atkinson, R. and Brook, J. and Chang, H. and Haddad, P. and Hoek, G. and Kappeler, R. and Sagiv, S. and Smargiassi, A. and Szpiro, A. and Vienneau, D. and Weuve, J. and Lurmann, F. and Forastiere, F. and Hoffmann, B. H.. (2023) Long-term exposure to traffic-related air pollution and diabetes: a systematic review and meta-analysis. International journal of public health, 68. p. 1605718.

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Abstract

Objectives: We report results of a systematic review on the health effects of long-term traffic-related air pollution (TRAP) and diabetes in the adult population. Methods: An expert Panel appointed by the Health Effects Institute conducted this systematic review. We searched the PubMed and LUDOK databases for epidemiological studies from 1980 to July 2019. TRAP was defined based on a comprehensive protocol. Random-effects meta-analyses were performed. Confidence assessments were based on a modified Office for Health Assessment and Translation (OHAT) approach, complemented with a broader narrative synthesis. We extended our interpretation to include evidence published up to May 2022. Results: We considered 21 studies on diabetes. All meta-analytic estimates indicated higher diabetes risks with higher exposure. Exposure to NO(2) was associated with higher diabetes prevalence (RR 1.09; 95% CI: 1.02; 1.17 per 10 mug/m(3)), but less pronounced for diabetes incidence (RR 1.04; 95% CI: 0.96; 1.13 per 10 mug/m(3)). The overall confidence in the evidence was rated moderate, strengthened by the addition of 5 recently published studies. Conclusion: There was moderate evidence for an association of long-term TRAP exposure with diabetes.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health Systems Research > Physical Hazards and Health (Röösli)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health Systems Research > Environmental Exposure Modelling (Vienneau)
UniBasel Contributors:Kutlar Joss, Meltem and Kappeler, Ron and Vienneau, Danielle
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:1661-8556
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
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Last Modified:06 Jul 2023 09:26
Deposited On:06 Jul 2023 09:26

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