Heule, Rahel and Celicanin, Zarko and Kozerke, Sebastian and Bieri, Oliver. (2018) Simultaneous multislice triple-echo steady-state (SMS-TESS): T1, T2, PD, and off-resonance mapping in the human brain. Magnetic Resonance in Medicine, 80 (3). pp. 1088-1100.
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Official URL: https://edoc.unibas.ch/94997/
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Abstract
Purpose : To investigate the ability of simultaneous multislice triple-echo steady-state (SMS- TESS) imaging to provide quantitative maps of multiple tissue parameters, i.e., longitudinal and transverse relaxation times (T 1 and T 2 ), proton density (PD), and off-resonance ( ∆ B 0 ), in the human brain at 3 T from a single scan. Methods : TESS acquisitions were performed in 2D mode to reduce motion sensitivity and accelerated by a simultaneous multislice excitation scheme (CAIPIRINHA) with SENSE reconstruction. SMS-acceleration factors (R) of 2 and 4 were evaluated. The in vitro and in vivo validation process included standard reference scans to analyze the accuracy of T 1 , T 2 , and B 0 estimates, as well as single-slice TESS measurements. Results : For R=2, the quantification of T 1 , T 2 , PD, and ∆ B 0 was overall reliable with marginal noise enhancement. T 1 and T 2 values were in good agreement with the reference measurements and single-slice TESS. For R=4, the agreement of B 0 with the standard reference was excellent and the determination of T 1 , T 2 , and PD was reproducible, however, increased variations in T 1 and T 2 values with respect to single-slice TESS were observed. Conclusion : SMS-TESS has shown potential to offer rapid simultaneous T 1 , T 2 , PD, and ∆ B 0 mapping of human brain tissues.
Faculties and Departments: | 03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Radiologische Physik (Bieri) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Radiologische Physik (Bieri) |
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UniBasel Contributors: | Bieri, Oliver |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | Wiley |
ISSN: | 0740-3194 |
e-ISSN: | 1522-2594 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Language: | English |
Identification Number: |
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edoc DOI: | |
Last Modified: | 20 Jun 2023 09:09 |
Deposited On: | 20 Jun 2023 09:09 |
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