Saucy, A. and Ragettli, M. S. and Vienneau, D. and de Hoogh, K. and Tangermann, L. and Schaffer, B. and Wunderli, J. M. and Probst-Hensch, N. and Röösli, M.. (2021) The role of extreme temperature in cause-specific acute cardiovascular mortality in Switzerland: a case-crossover study. The science of the total environment, 790. p. 147958.
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Official URL: https://edoc.unibas.ch/89413/
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Abstract
Since the 2003 heatwave in Europe, evidence has been rapidly increasing on the association between extreme temperature and all-cause mortality. Little is known, however, about cause-specific cardiovascular mortality, effect modification by air pollution and aircraft noise, and which population groups are the most vulnerable to extreme temperature. We conducted a time-stratified case-crossover study in Zurich, Switzerland, including all adult cardiovascular deaths between 2000 and 2015 with precise individual exposure estimates at home location. We estimated the risk of 24,884 cardiovascular deaths associated with heat and cold using distributed non-linear lag models. We investigated potential effect modification of temperature-related mortality by fine particles, nitrogen dioxide, and night-time aircraft noise and performed stratified analyses across individual and social characteristics. We found increased risk of mortality for heat (odds ratio OR = 1.28 [95% confidence interval: 1.11-1.49] for 99th percentile of daily Tmean (24 degrees C) versus optimum temperature at 20 degrees C) and cold (OR = 1.15 [0.95-1.39], 5th percentile of daily Tmean (-3 degrees C) versus optimum temperature at 20 degrees C). Heat-related mortality was particularly strong for myocardial infarctions and hypertension related deaths, and among older women (>75 years). Analysis of effect modification also indicated that older women with lower socio-economic position and education are at higher risk for heat-related mortality. PM2.5 increased the risk of heat-related mortality for heart failure, but not all-cause cardiovascular mortality. This study provides useful information for preventing cause-specific cardiovascular temperature-related mortality in moderate climate zones comparable to Switzerland.
Faculties and Departments: | 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Exposome Science (Probst-Hensch) 03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Exposome Science (Probst-Hensch) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health Systems Research > Physical Hazards and Health (Röösli) |
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UniBasel Contributors: | Saucy, Apolline and de Hoogh, Kees and Vienneau, Danielle and Tangermann, Louise and Probst-Hensch, Nicole and Röösli, Martin and Ragettli, Martina |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
ISSN: | 0048-9697 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Language: | English |
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edoc DOI: | |
Last Modified: | 21 Dec 2022 10:35 |
Deposited On: | 21 Dec 2022 10:35 |
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