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Clustered cardiovascular disease risk among children aged 8-13 years from lower socioeconomic schools in Gqeberha, South Africa

Dolley, Danielle and Walter, Cheryl and du Randt, Rosa and Pühse, Uwe and Bosma, Jacob and Aerts, Ann and Adams, Larissa and Arnaiz, Patricia and Degen, Jan and Gall, Stefanie and Joubert, Nandi and Müller, Ivan and Nienhaber, Madeleine and Nqweniso, Felicitas and Seelig, Harald and Steinmann, Peter and Utzinger, Jürg and Gerber, Markus. (2022) Clustered cardiovascular disease risk among children aged 8-13 years from lower socioeconomic schools in Gqeberha, South Africa. BMJ Open Sport & Exercise Medicine, 8 (2). 8:e001336.

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Abstract

Objectives To determine the prevalence of individual cardiovascular disease (CVD) risk factors and clustered CVD risk among children attending schools in periurban areas of Gqeberha and to investigate the independent association between clustered CVD risk, moderate to vigorous physical activity (MVPA) and cardiorespiratory fitness (CRF). Methods Baseline data were collected in a cross-sectional analysis of 975 children aged 8-13 years. We measured the height, weight, waist circumference, blood pressure, fasting glucose, full lipid panel, 20 m shuttle run performance and accelerometry. The prevalence of individual risk factors was determined, and a clustered risk score (CRS) was constructed using principal component analysis. Children with an elevated CRS of 1 SD above the average CRS were considered 'at-risk'. Results We found 424 children (43.3%) having at least one elevated CVD risk factor: 27.7% elevated triglycerides, 20.7% depressed high-density lipoprotein cholesterol and 15.9% elevated total cholesterol. An elevated clustered risk was identified in 17% (n=104) of the sample; girls exhibited a significantly higher CRS >1 SD than boys (p=0.036). The estimated odds of an elevated clustered risk are doubled every 2 mL/kg/min decrease in VO 2 max (95% CI 1.66 to 3.12) or every 49 min reduction in MVPA (95% CI 27 to 224). Conclusion A relatively high prevalence of elevated individual and clustered CVD risk was identified. Our results have also confirmed the independent inverse association of the clustered CVD risk with physical activity and CRF. These indicate that increased levels of CRF or MVPA may aid in the prevention and reduction of elevated clustered CVD risk.
Faculties and Departments:03 Faculty of Medicine > Departement Sport, Bewegung und Gesundheit > Bereich Sportwissenschaft > Sportwissenschaften (Pühse)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Swiss Centre for International Health (SCIH) > Health Systems Support (Prytherch)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Health Impact Assessment (Utzinger)
UniBasel Contributors:Pühse, Uwe and Arnaiz Jimenez, Patricia and Degen, Jan and Joubert, Nandi and Müller, Ivan and Seelig, Harald and Gerber, Markus and Steinmann, Peter and Utzinger, Jürg
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:BMJ
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
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Last Modified:24 Nov 2022 04:10
Deposited On:09 Jul 2022 07:21

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