Sugihara, Kaori and Chami, Mohamed and Derényi, Imre and Vörös, János and Zambelli, Tomaso. (2012) Directed self-assembly of lipid nanotubes from inverted hexagonal structures. ACS Nano, 6 (8). pp. 6626-6632.
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Official URL: https://edoc.unibas.ch/87963/
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Abstract
Conventional lipid-tube formation is based on either a tube phase of certain lipids or the shape transformation of lamellar structures by applying a point load. In the present study, lipid blocks in inverted hexagonal phase made of 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) were shown to protrude lipid nanotubes upon a fluid-dynamic flow on polyelectrolyte-functionalized surfaces in physiological buffer solution. The outer diameter of the tubes is 19.1 ± 4.5 nm and their lengths are up to several hundred micrometers. The method described enables the alignment and patterning of lipid nanotubes into various (including curvy) shapes with a microfluidic system.
| Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Structural Biology (Engel) 05 Faculty of Science > Departement Biozentrum > Services Biozentrum > BioEM Lab (Chami) |
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| UniBasel Contributors: | Chami, Mohamed |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | American Chemical Society |
| ISSN: | 1936-0851 |
| e-ISSN: | 1936-086X |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 09 Mar 2022 11:25 |
| Deposited On: | 09 Mar 2022 11:25 |
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