Cohort profile: The Swiss Transplant Cohort Study (STCS): A nationwide longitudinal cohort study of all solid organ recipients in Switzerland

Stampf, Susanne and Mueller, Nicolas J. and van Delden, Christian and Pascual, Manuel and Manuel, Oriol and Banz, Vanessa and Binet, Isabelle and De Geest, Sabina and Bochud, Pierre-Yves and Leichtle, Alexander and Schaub, Stefan and Steiger, Jürg and Koller, Michael and Swiss Transplant Cohort Study, and members of the Swiss Transplant Cohort Study, . (2021) Cohort profile: The Swiss Transplant Cohort Study (STCS): A nationwide longitudinal cohort study of all solid organ recipients in Switzerland. BMJ Open, 11 (12). e051176.

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Official URL: https://edoc.unibas.ch/85834/

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The Swiss Transplant Cohort Study (STCS) is a prospective multicentre cohort study which started to actively enrol study participants in May 2008. It takes advantage of combining data from all transplant programmes in one unique system to perform comprehensive nationwide reporting and to promote translational and clinical post-transplant outcome research in the framework of Swiss transplantation medicine.; Over 5500 solid organ transplant recipients have been enrolled in all six Swiss transplant centres by end of 2019, around three-quarter of them for kidney and liver transplants. Ninety-three per cent of all transplanted recipients have consented to study participation, almost all of them (99%) contributed to bio-sampling. The STCS genomic data set includes around 3000 patients.; Detailed clinical and laboratory data in high granularity as well as patient-reported outcomes from transplant recipients and activities in Switzerland are available in the last decade. Interdisciplinary contributions in diverse fields of transplantation medicine such as infectious diseases, genomics, oncology, immunology and psychosocial science have resulted in approximately 70 scientific papers getting published in peer-review journals so far.; The STCS will deepen its efforts in personalised medicine and digital epidemiology, and will also focus on allocation research and the use of causal inference methods to make complex matters in transplant medicine more understandable and transparent.
Faculties and Departments:03 Faculty of Medicine > Departement Public Health > Institut für Pflegewissenschaft
UniBasel Contributors:De Geest, Sabina M.
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:BMJ Publishing Group
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Apr 2022 15:23
Deposited On:01 Apr 2022 15:23

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