Association of psychosocial factors with all-cause hospitalizations in patients with atrial fibrillation

Meyre, Pascal B. and Springer, Anne and Aeschbacher, Stefanie and Blum, Steffen and Rodondi, Nicolas and Beer, Juerg H. and Di Valentino, Marcello and Ammann, Peter and Blum, Manuel and Mathys, Rebecca and Meyer-Zürn, Christine and Bonati, Leo H. and Sticherling, Christian and Schwenkglenks, Matthias and Kühne, Michael and Conen, David and Osswald, Stefan and Swiss-AF investigators, . (2021) Association of psychosocial factors with all-cause hospitalizations in patients with atrial fibrillation. Clinical cardiology, 44 (1). pp. 51-57.

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A high burden of cardiovascular comorbidities puts patients with atrial fibrillation (AF) at high risk for hospitalizations, but the role of other factors is less clear.; To determine the relationship between psychosocial factors and the risk of unplanned hospitalizations in AF patients.; Prospective observational cohort study of 2378 patients aged 65 or older with previously diagnosed AF across 14 centers in Switzerland. Marital status and education level were defined as social factors, depression and health perception were psychological components. The pre-defined outcome was unplanned all-cause hospitalization.; During a median follow-up of 2.0 years, a total of 1713 hospitalizations occurred in 37% of patients. Compared to patients who were married, adjusted rate ratios (aRR) for all-cause hospitalizations were 1.28 (95% confidence interval [CI], 0.97-1.69) for singles, 1.31 (95%CI, 1.06-1.62) for divorced patients, and 1.02 (95%CI, 0.82-1.25) for widowed patients. The aRRs for all-cause hospitalizations across increasing quartiles of health perception were 1.0 (highest health perception), 1.15 (95%CI, 0.84-1.59), 1.25 (95%CI, 1.03-1.53), and 1.66 (95%CI, 1.34-2.07). No different hospitalization rates were observed in patients with a secondary or primary or less education as compared to patients with a college degree (aRR, 1.06; 95%CI, 0.91-1.23 and 1.05; 95%CI, 0.83-1.33, respectively). Presence of depression was not associated with higher hospitalization rates (aRR, 0.94; 95%CI, 0.68-1.29).; The findings suggest that psychosocial factors, including marital status and health perception, are strongly associated with the occurrence of hospitalizations in AF patients. Targeted psychosocial support interventions may help to avoid unnecessary hospitalizations.; ClinicalTrials.gov Identifier NCT02105844.
Faculties and Departments:03 Faculty of Medicine > Departement Public Health > Pharmazeutische Medizin ECPM > Pharmazeutische Medizin (Szucs)
UniBasel Contributors:Schwenkglenks, Matthias
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:31 Aug 2021 10:21
Deposited On:31 Aug 2021 10:21

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