Knezevic, Melina and Heilmann, Michael and Piccini, GiovanniMaria and Tiefenbacher, Konrad. (2020) Overriding Intrinsic Reactivity in Aliphatic C-H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrate. Angewandte Chemie International Edition, 59 (30). pp. 12387-12391.
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Official URL: https://edoc.unibas.ch/81125/
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Abstract
The site‐selective C−H oxidation of unactivated positions in aliphatic ammonium chains poses a tremendous synthetic challenge, for which a solution has not yet been found. Here, we report the preferential oxidation of the strongly deactivated C3/C4 positions of aliphatic ammonium substrates by employing a novel supramolecular catalyst. This chimeric catalyst was synthesized by linking the well‐explored catalytic moiety Fe(pdp) to an alkyl ammonium binding molecular tweezer. The results highlight the vast potential of overriding the intrinsic reactivity in chemical reactions by guiding catalysis using supramolecular host structures that enable a precise orientation of the substrates.
Faculties and Departments: | 05 Faculty of Science > Departement Chemie 05 Faculty of Science > Departement Chemie > Chemie > Synthesis of Functional Modules (Tiefenbacher) |
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UniBasel Contributors: | Knezevic, Melina and Heilmann, Michael and Piccini, GiovanniMaria and Tiefenbacher, Konrad |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | Wiley |
ISSN: | 1433-7851 |
e-ISSN: | 1521-3773 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Language: | English |
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edoc DOI: | |
Last Modified: | 26 May 2021 01:30 |
Deposited On: | 16 Feb 2021 09:20 |
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