edoc

Overriding Intrinsic Reactivity in Aliphatic C-H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrate

Knezevic, Melina and Heilmann, Michael and Piccini, GiovanniMaria and Tiefenbacher, Konrad. (2020) Overriding Intrinsic Reactivity in Aliphatic C-H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrate. Angewandte Chemie International Edition, 59 (30). pp. 12387-12391.

[img] PDF - Accepted Version
Restricted to Repository staff only until 26 May 2021.

575Kb

Official URL: https://edoc.unibas.ch/81125/

Downloads: Statistics Overview

Abstract

The site‐selective C−H oxidation of unactivated positions in aliphatic ammonium chains poses a tremendous synthetic challenge, for which a solution has not yet been found. Here, we report the preferential oxidation of the strongly deactivated C3/C4 positions of aliphatic ammonium substrates by employing a novel supramolecular catalyst. This chimeric catalyst was synthesized by linking the well‐explored catalytic moiety Fe(pdp) to an alkyl ammonium binding molecular tweezer. The results highlight the vast potential of overriding the intrinsic reactivity in chemical reactions by guiding catalysis using supramolecular host structures that enable a precise orientation of the substrates.
Faculties and Departments:05 Faculty of Science > Departement Chemie
05 Faculty of Science > Departement Chemie > Chemie > Synthesis of Functional Modules (Tiefenbacher)
UniBasel Contributors:Knezevic, Melina and Heilmann, Michael and Piccini, GiovanniMaria and Tiefenbacher, Konrad
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Wiley
ISSN:1433-7851
e-ISSN:1521-3773
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
edoc DOI:
Last Modified:02 Mar 2021 15:35
Deposited On:16 Feb 2021 09:20

Repository Staff Only: item control page